Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Nectar
Collect Nectar points
Nectar
Collect Nectar points
Nectar
Collect Nectar points

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Santiago 5 Star Hotels

See all 707 Hotels in Santiago
W Santiago

W Santiago

Isidora Goyenechea 3000, Santiago
5.0 out of 5.0
4.3 out of 5 (189 reviews)
Great location and wonderful serviceNothing to fault - room, service & facilities perfect in every way possible.
  11 Oct 2017

£220

£220
InterContinental Santiago

InterContinental Santiago

Av. Vitacura 2885, Santiago
5.0 out of 5.0
3.7 out of 5 (162 reviews)
Nice hotel good location Booked last minute was very pleased for my short stay
  23 Jun 2017

£64

£64
Luciano K Hotel

Luciano K Hotel

Merced, 84, Santiago
5.0 out of 5.0
4.5 out of 5 (199 reviews)
Art Deco hotel. Clean, comfortable and centralGreat location in the centre of town. Clean comfortable and with lots of original art deco features. Especially the original lift. The first hotel in Chile with a lift.
  29 Jan 2018

£88

£88
Noi Vitacura

Noi Vitacura

Av. Nueva Costanera 3736, Santiago
5.0 out of 5.0
4.4 out of 5 (198 reviews)
Rooms just ok. Great location and some good views.The carpets in the rooms are very old and the decor is not special. The second floor was very noisy from the restaurant next door and from the guests coming into the hotel speaking loudly. The six floor facing the back street was fine. Great view to the mountains from the terrace and from some of ...
  22 Jan 2018

£164

£164
The Singular Santiago

The Singular Santiago

Merced 294, Santiago
5.0 out of 5.0
4.9 out of 5 (135 reviews)
Power OutageThe power went out in the area surrounding the hotel and they had an issue getting the generator to work. Staff was very helpful and keep things moving along as best as possible
  22 Jan 2018

£204

£204
Hotel Santiago

Hotel Santiago

Kennedy Avenue #4601, Santiago
5.0 out of 5.0
4.4 out of 5 (329 reviews)
It’s a nice place It’s a nice place, the building has good bones... change management from Hyatt to mandarin hotel... the place under Hyatt become tired look so new mandarin is doing a renovation to bring back the flash from early years this great building... when is completed will be incredibly now still a great ...
  18 Nov 2017

£156

£156
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

Calle El Alcalde 15, Santiago
5.0 out of 5.0
4.6 out of 5 (149 reviews)
city centre luxuryAfter a painfully slow check in (15 mins +) the staff were excellent.
  17 Feb 2018

£219

£219
Lastarria Boutique Hotel

Lastarria Boutique Hotel

Coronel Santiago Bueras 188, Santiago
5.0 out of 5.0
4.6 out of 5 (241 reviews)
Best Hotel in the Neighborhood This hotel is nice and comfortable. The reception is excellent and they are very kind, the room is clean, same as the bathroom. Our room has a small terrace and goes directly to the swimming pool, which is really amazing. The restaurant is pretty good, breakfast was buffet, small but with necessary ...
  22 Jan 2018

£116

£116
Sheraton Santiago Hotel and Convention Center

Sheraton Santiago Hotel and Convention Center

Ave Santa Maria 1742, Santiago
5.0 out of 5.0
3.9 out of 5 (107 reviews)
nice hotel, taxi drivers are thieveshotel really good, but hey should warn their guest not to take cabs , I got robbed 3 times in 4 days. when I got back to the hotel and told what happened they told me they all ready knew that it was something cab drivers often do, they change your money really fast and you don't even notice... just ...
  7 Nov 2017

£131

£131
Renaissance Santiago Hotel

Renaissance Santiago Hotel

Avenida Kennedy 4700, Santiago
5.0 out of 5.0
4.6 out of 5 (202 reviews)
All employees in the hotel are Very helpful and very considerate
  9 Feb 2018

£115

£115
Map

Pocket Guide: 5 Star Hotels in Santiago

Search for hotels in Santiago on Expedia.co.uk. You can easily find your hotels in Santiago using one of the methods below:

  • View our selection of featured hotels in Santiago
  • Use the map to find hotels in the Santiago neighborhood you prefer
  • Use the filters to see hotels in a specific area of Santiago, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Santiago
  • Enter your travel dates to view the best deals on hotels in Santiago - while they last

Recently booked Santiago hotels

Best Western Premier Marina Las Condes
4.5 out of 5.0
Last booking: 6 minutes ago
Apart Hotel B
4.0 out of 5.0
Last booking: 7 minutes ago
NH Collection Plaza Santiago
4.5 out of 5.0
Last booking: 1 hour ago
Hotel Plaza San Francisco
4.5 out of 5.0
Last booking: 1 hour ago
Plaza El Bosque San Sebastian
4.5 out of 5.0
Last booking: 4 hours ago
Hotel Fundador
3.5 out of 5.0
Last booking: 4 hours ago
Hyatt Place Santiago/Vitacura
3.5 out of 5.0
Last booking: 4 hours ago
Hotel Atton Las Condes
4.0 out of 5.0
Last booking: 4 hours ago
Santiago Marriott Hotel
5.0 out of 5.0
Last booking: 4 hours ago