Title: The 10 Best 5 Star Hotels in Santa Fe Island - 2025 Updated Prices | Expedia.co.uk [Santa Fe Island Travel Guide](https://expedia.co.uk/Santa-Fe-Island.dx6336630)[Hotels in Santa Fe Island](https://expedia.co.uk/Santa-Fe-Island-Hotels.d6336630.Travel-Guide-Hotels)[Holiday Rentals in Santa Fe Island](https://expedia.co.uk/Santa-Fe-Island-Holiday-Rentals.d6336630.Travel-Guide-HolidayRentals)[Flights to Santa Fe Island](https://expedia.co.uk/Cheap-Flights-To-Santa-Fe-Island.d6336630.Travel-Guide-Flights)[Santa Fe Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe-Island.d6336630.Car-Hire-Guide)[Santa Fe Island Holidays](https://expedia.co.uk/Santa-Fe-Island.d6336630.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/2/b409b6f186c01b1ddccd1e8276ed7b60.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jason Karas # Compare and book 5 Star hotels in Santa Fe Island, Galápagos ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Fe Island 5 Star Hotels Tonight [16 Oct - 17 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2025-10-16&endDate=2025-10-17&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [17 Oct - 18 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2025-10-17&endDate=2025-10-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Fe Island 5 Star Hotels ![BBQ/picnic Area](https://images.trvl-media.com/lodging/100000000/99530000/99523000/99522986/5d3c0d78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, pillow-top beds, minibar, individually furnished](https://images.trvl-media.com/lodging/100000000/99530000/99523000/99522986/41e363f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Condo, 3 Bedrooms | Private kitchen | Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/100000000/99530000/99523000/99522986/678f4a46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/100000000/99530000/99523000/99522986/0516fdcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galapagos and Beyond Puerto Ayora 10/10 Exceptional (6) "Great stay! The rooms, the service, the breakfast, everything was great. Definitely stay here" [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-And-Beyond.h99522986.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Fe Island. ![Finch Bay Galapagos Hotel](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Finch Bay Galapagos Hotel Barrio Punta Estrada, Puerto Ayora, Galapagos £393 19 Oct - 20 Oct 9.2/10 Wonderful! (87 reviews) [](https://expedia.co.uk/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) ![Hotel Cucuve](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/733c9cb5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Cucuve Charles Binford 083 y Ave Charles Darwin, Puerto Ayora £131 25 Oct - 26 Oct 9.8/10 Exceptional! (265 reviews) [](https://expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) ![Blu Galapagos Sustainable Waterfront Lodge](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/4a332d25_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Blu Galapagos Sustainable Waterfront Lodge Ave. Charles Darwin S/n Y Piquero, Puerto Ayora, Galapagos £129 29 Oct - 30 Oct 8.6/10 Excellent! (120 reviews) [](https://expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) Still don't see what you're looking for? [See all properties in Santa Fe Island.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=18%2F10%2F2025&endDate=19%2F10%2F2025®ionId=6336630&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=18%2F10%2F2025&endDate=19%2F10%2F2025®ionId=6336630&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=18%2F10%2F2025&endDate=19%2F10%2F2025®ionId=6336630&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=18%2F10%2F2025&endDate=19%2F10%2F2025®ionId=6336630&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=18%2F10%2F2025&endDate=19%2F10%2F2025®ionId=6336630&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=18%2F10%2F2025&endDate=19%2F10%2F2025®ionId=6336630&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Santa Fe Island Marvel at dense forests of prickly pear, pose for a photo next to a sunbathing sea lion and spot endemic iguanas and rats. [See all hotels in Santa Fe Island](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-31&endDate=2025-11-01&adults=2®ionId=6336630) ![](https://mediaim.expedia.com/destination/2/b409b6f186c01b1ddccd1e8276ed7b60.jpg?impolicy=fcrop&w=900&h=675&p=1&q=high) Photo by Jason Karas ## Top Santa Fe Island Hotel Reviews ## Find out more about Santa Fe Island ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in North Seymour Island](https://www.expedia.co.uk/4Star-North-Seymour-Island-Hotels.s40-0-d6336659.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Seymour Island](https://www.expedia.co.uk/5Star-North-Seymour-Island-Hotels.s50-0-d6336659.Travel-Guide-Filter-Hotels) - [Baltra Hotels](https://www.expedia.co.uk/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Bellavista Hotels](https://www.expedia.co.uk/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - [Hotels near Charles Darwin Research Station](https://www.expedia.co.uk/Charles-Darwin-Research-Station-Hotels.0-l6171312-0.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Beach-Hotels.0-0-d1371-tBeachHotels.Hotel-Filter-Destinations) - [Cheap Hotels in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Budget-Hotels.0-0-d1371-tBudgetHotels.Hotel-Filter-Destinations) - [Family-Friendly Hotels in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Family-Friendly-Hotel.0-0-d1371-tFamilyFriendlyHotel.Hotel-Filter-Destinations) - [Gay-Friendly Hotels in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Gay-Friendly-Hotel.0-0-d1371-tGayFriendlyHotel.Hotel-Filter-Destinations) - [Hotels with Babysitting Services in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Hotel-With-Babysitting-Services.0-0-d1371-thotelwithbabysittingservices.Hotel-Filter-Destinations) - [Hotels with Gym in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Hotel-With-Gym.0-0-d1371-thotelwithgym.Hotel-Filter-Destinations) - [Luxury Hotels in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Luxury-Hotel.0-0-d1371-tLuxuryHotel.Hotel-Filter-Destinations) - 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[Resorts in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotel-Resorts.d6053670-aaHotelResorts.Travel-Guide-Accommodation) - [Beach Resorts & in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Beach-Hotels.0-0-d6053670-tBeachHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Boutique-Hotel.0-0-d6053670-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Budget-Hotels.0-0-d6053670-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Family-Friendly-Hotel.0-0-d6053670-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels Suites in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Hotel-Suites.0-0-d6053670-thotelsuites.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Hotels-With-Smoking-Rooms.0-0-d6053670-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Luxury-Hotel.0-0-d6053670-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Marina Hotels in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Marina-Hotel.0-0-d6053670-tmarinahotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Pet-Friendly-Hotel.0-0-d6053670-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Spa-Hotels.0-0-d6053670-tSpaHotels.Travel-Guide-Filter-Hotels) - [Wedding Hotels in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels-Wedding-Hotel.0-0-d6053670-tWeddingHotel.Travel-Guide-Filter-Hotels) - [Santa Cruz Island Hotels](https://www.expedia.co.uk/Santa-Cruz-Island-Hotels.d6053670.Travel-Guide-Hotels) - [Lodges in Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island-Lodges.d6053670-aaLodges.Travel-Guide-Accommodation) - [Santa Rosa Hotels](https://www.expedia.co.uk/Santa-Rosa-Hotels.d6053725.Travel-Guide-Hotels) - [Hotels near Seymour](https://www.expedia.co.uk/Seymour-Airport-Hotels.0-aGPS-0.Travel-Guide-Filter-Hotels) - [Flights to Baltra](https://www.expedia.co.uk/Cheap-Flights-To-Baltra.d6223000.Travel-Guide-Flights) - [Flights to North Seymour Island](https://www.expedia.co.uk/Cheap-Flights-To-North-Seymour-Island.d6336659.Travel-Guide-Flights) - [Flights to Puerto Ayora](https://www.expedia.co.uk/Cheap-Flights-To-Puerto-Ayora.d602686.Travel-Guide-Flights) - [Flights to Puerto Baquerizo Moreno](https://www.expedia.co.uk/Cheap-Flights-To-Puerto-Baquerizo-Moreno.d6138894.Travel-Guide-Flights) - [Flights to Santa Cruz Island](https://www.expedia.co.uk/Cheap-Flights-To-Santa-Cruz-Island.d6053670.Travel-Guide-Flights) - [Flights to Seymour](https://www.expedia.co.uk/Cheap-Flights-To-Seymour.d6024439.Travel-Guide-Flights) - [Flights to Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Flights from Seymour](https://www.expedia.co.uk/lp/airports/gps/flights-from-seymour-airport) - [Flights from Bogotá (BOG) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/bog/scy/bogota-to-san-cristobal) - [Flights from Cartagena (CTG) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/ctg/gps/cartagena-to-isla-baltra) - [Flights from Edinburgh (EDI) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/edi/scy/edinburgh-to-san-cristobal) - [Flights from Isla Baltra (GPS) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/gps/scy/isla-baltra-to-san-cristobal) - [Flights from Guayaquil (GYE) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/gye/gps/guayaquil-to-isla-baltra) - [Flights from Guayaquil (GYE) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/gye/scy/guayaquil-to-san-cristobal) - [Flights from London (LGW) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/lgw/gps/london-to-isla-baltra) - [Flights from London (LGW) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/lgw/scy/london-to-san-cristobal) - [Flights from London (LHR) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/lhr/gps/london-to-isla-baltra) - [Flights from London (LHR) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/lhr/scy/london-to-san-cristobal) - [Flights from Manchester (MAN) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/man/gps/manchester-to-isla-baltra) - [Flights from Manchester (MAN) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/man/scy/manchester-to-san-cristobal) - [Flights from Mexico City (MEX) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/mex/scy/mexico-city-to-san-cristobal) - [Flights from Miami (MIA) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/mia/gps/miami-to-isla-baltra) - [Flights from Newcastle (NCL) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/ncl/scy/newcastle-to-san-cristobal) - [Flights from Oaxaca Intl. (OAX) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/oax/scy/oaxaca-intl-to-san-cristobal) - [Flights from Coca (OCC) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/occ/gps/coca-to-isla-baltra) - [Flights from Puerto Escondido (PXM) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/pxm/scy/puerto-escondido-to-san-cristobal) - [Flights from Santiago (SCL) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/scl/gps/santiago-to-isla-baltra) - [Flights from Quito (UIO) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/uio/gps/quito-to-isla-baltra) - [Flights from Quito (UIO) to San Cristobal (SCY)](https://www.expedia.co.uk/lp/flights/uio/scy/quito-to-san-cristobal) - [Baltra Holidays](https://www.expedia.co.uk/Baltra.d6223000.Holidays-City-Breaks) - [Charles Darwin Research Station](https://www.expedia.co.uk/Charles-Darwin-Research-Station-Galapagos.d6171312.Attraction) - [Visit El Cascajo](https://www.expedia.co.uk/El-Cascajo.dx6222749) - [Galápagos Holidays](https://www.expedia.co.uk/Galapagos.d1371.Holidays-City-Breaks) - [Visit Galápagos](https://www.expedia.co.uk/Galapagos.dx1371) - [Visit North Seymour Island](https://www.expedia.co.uk/North-Seymour-Island.dx6336659) - [Playa de los Alemanes](https://www.expedia.co.uk/Playa-De-Los-Alemanes-Puerto-Ayora.d553248625325955800.Attraction) - [Puerto Ayora Holidays](https://www.expedia.co.uk/Puerto-Ayora.d602686.Holidays-City-Breaks) - [Visit Puerto Ayora](https://www.expedia.co.uk/Puerto-Ayora.dx602686) - [Puerto Baquerizo Moreno Holidays](https://www.expedia.co.uk/Puerto-Baquerizo-Moreno.d6138894.Holidays-City-Breaks) - [Visit Puerto Baquerizo Moreno](https://www.expedia.co.uk/Puerto-Baquerizo-Moreno.dx6138894) - [Santa Cruz Island Holidays](https://www.expedia.co.uk/Santa-Cruz-Island.d6053670.Holidays-City-Breaks) - [Visit Santa Cruz Island](https://www.expedia.co.uk/Santa-Cruz-Island.dx6053670) - [Visit Santa Rosa](https://www.expedia.co.uk/Santa-Rosa.dx6053725) - [Tortuga Bay Beach](https://www.expedia.co.uk/Tortuga-Bay-Beach-Bella-Vista.d6171324.Attraction) - [Yoga Holiday Packages Santa Cruz Island](https://www.expedia.co.uk/lp/theme-holidays/yoga-holidays/6053670/Santa-Cruz-Island) - [Avis Rental Cars in North Seymour Island](https://www.expedia.co.uk/Avis-Car-Rentals-In-North-Seymour-Island.d6336659-c41.Car-Rental-Guide-Suppliers) - [Car hire Puerto Ayora](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Puerto-Ayora.d602686.Car-Hire-Guide) - [Car hire near Santa Cruz Island](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz-Island.d6053670.Car-Hire-Guide) - [Rental cars Seymour airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Seymour.d6024439.Car-Hire-Guide) - [Car hire near Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Car-Hire-Destinations) - [Greenmotion Rental Cars in North Seymour Island](https://www.expedia.co.uk/Greenmotion-Car-Rentals-In-North-Seymour-Island.d6336659-c1093.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in North Seymour Island](https://www.expedia.co.uk/Thrifty-Car-Rental-Car-Rentals-In-North-Seymour-Island.d6336659-c45.Car-Rental-Guide-Suppliers) - [Top Rent a Car Rental Cars in Santa Cruz Island](https://www.expedia.co.uk/Top-Rent-A-Car-Car-Rentals-In-Santa-Cruz-Island.d6053670-c1028.Car-Rental-Guide-Suppliers) - [Baltra Holiday Rentals](https://www.expedia.co.uk/Baltra-Holiday-Rentals.d6223000.Travel-Guide-HolidayRentals) - [Bellavista Holiday Rentals](https://www.expedia.co.uk/Bellavista-Holiday-Rentals.d6342722.Travel-Guide-HolidayRentals) - [Galápagos Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Holiday-Rental-Destinations) - [Santa Cruz Island Holiday Rentals](https://www.expedia.co.uk/Santa-Cruz-Island-Holiday-Rentals.d6053670.Travel-Guide-HolidayRentals) - [Santa Rosa Holiday Rentals](https://www.expedia.co.uk/Santa-Rosa-Holiday-Rentals.d6053725.Travel-Guide-HolidayRentals) - [Things to do in Baltra](https://www.expedia.co.uk/Things-To-Do-In-Baltra.d6223000.Travel-Guide-Activities) - [Things to do in Galápagos](https://www.expedia.co.uk/Things-To-Do-In-Galapagos.d1371.Travel-Guide-Activities) - [Things to do in North Seymour Island](https://www.expedia.co.uk/Things-To-Do-In-North-Seymour-Island.d6336659.Travel-Guide-Activities) - [Things to do in Puerto Ayora](https://www.expedia.co.uk/Things-To-Do-In-Puerto-Ayora.d602686.Travel-Guide-Activities) - [Things to do in Santa Cruz Island](https://www.expedia.co.uk/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)