Title: The 10 Best 5 Star Hotels in Jeffersonville - Clarksville - 2025 Updated Prices | Expedia.co.uk [Jeffersonville - Clarksville Travel Guide](https://expedia.co.uk/Jeffersonville-Clarksville.dx6059638)[Hotels in Jeffersonville - Clarksville](https://expedia.co.uk/Jeffersonville-Clarksville-Hotels.d6059638.Travel-Guide-Hotels)[Holiday Rentals in Jeffersonville - Clarksville](https://expedia.co.uk/Jeffersonville-Clarksville-Holiday-Rentals.d6059638.Travel-Guide-HolidayRentals)[Flights to Jeffersonville - Clarksville](https://expedia.co.uk/Cheap-Flights-To-Jeffersonville-Clarksville.d6059638.Travel-Guide-Flights)[Jeffersonville - Clarksville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Jeffersonville-Clarksville.d6059638.Car-Hire-Guide)[Jeffersonville - Clarksville Holidays](https://expedia.co.uk/Jeffersonville-Clarksville.d6059638.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/55a2a839cfa643987144c792847283db.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Jeffersonville - Clarksville, Indiana ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Jeffersonville - Clarksville 5 Star Hotels Tonight [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2025-10-12&endDate=2025-10-13&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2025-10-13&endDate=2025-10-14&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059638&startDate=2025-10-24&endDate=2025-10-26&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Jeffersonville - Clarksville 5 Star Hotels ![Street view](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/ef55443d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/00819013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/c8e026b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/102000000/101180000/101176500/101176472/56e486f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Louisville Bourbon Inn Old Louisville 10/10 Exceptional (18) "Absolutely the best B&B we have ever stayed with." £230 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Louisville-Hotels-Louisville-Bourbon-Inn.h101176472.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Jeffersonville-Clarksville-Hotels.s50-0-d6059638.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Jeffersonville-Clarksville-Hotels.s50-0-d6059638.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Jeffersonville - Clarksville. ![Galt House Hotel Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Galt House Hotel Trademark Collection by Wyndham 140 North Fourth Street, Louisville, KY £122 30 Oct - 31 Oct includes taxes & fees 8.8/10 Excellent! (3,657 reviews) [](https://expedia.co.uk/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Omni Louisville Hotel](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Omni Louisville Hotel 400 S. 2nd Street, Louisville, KY £175 25 Oct - 26 Oct includes taxes & fees 9.2/10 Wonderful! (1,634 reviews) [](https://expedia.co.uk/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Embassy Suites Louisville Downtown](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Embassy Suites Louisville Downtown 501 South Fourth Street, Louisville, KY £122 31 Oct - 1 Nov includes taxes & fees 8.8/10 Excellent! (1,021 reviews) [](https://expedia.co.uk/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) Still don't see what you're looking for? [See all properties in Jeffersonville - Clarksville.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6059638&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6059638&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6059638&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6059638&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6059638&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=13%2F10%2F2025&endDate=14%2F10%2F2025®ionId=6059638&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Jeffersonville - Clarksville and related destinations - Jeffersonville - Clarksville - Casper - Quad Cities - Youngstown - Macon Discover the family-friendly area of Jeffersonville - Clarksville—a scenic riverfront, entertainment choices and sights from Derby Dinner Playhouse to Falls of the Ohio State Park. [See all hotels in Jeffersonville - Clarksville](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27&adults=2®ionId=6059638) ![](https://mediaim.expedia.com/destination/1/55a2a839cfa643987144c792847283db.jpg?impolicy=fcrop&w=900&h=597&p=1&q=high) ## Top Jeffersonville - Clarksville Hotel Reviews ## Find out more about Jeffersonville - Clarksville ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Jeffersonville - Clarksville? > You'll find many different pricing options for 5-star hotels in Jeffersonville - Clarksville on Expedia. The amount you pay will depend on when you want to travel, length of your trip and other factors. Compare all of the available accommodation for your desired dates and use our pricing and other filters to find the ideal luxury stay. > > > > - Search for the lowest price per night from £122 ### What makes a hotel 5 stars in Jeffersonville - Clarksville? > From fine dining restaurants and all-day gyms to swimming pools and the finest bedding, the 5-star experience in Jeffersonville - Clarksville is all about indulgence and comfort. But it requires more than just upscale amenities to get a 5-star rating. Stays also have to provide superb guest-focused services like in-room beauty treatments, dry cleaning and laundry and 24-hour room service. ### Are there any 5-star all-inclusive resorts in Jeffersonville - Clarksville? > Use our filters to find a luxurious escape in Jeffersonville - Clarksville where everything you need is included in the price. Next, refine your results for resorts that have a rating of 5 stars and are described as "All inclusive." The first thing to look forward to at these stays? 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