Title: The 10 Best 4 Star Hotels in Santa Fe Island - 2026 Updated Prices | Expedia.co.uk [Santa Fe Island Travel Guide](https://expedia.co.uk/Santa-Fe-Island.dx6336630)[Hotels in Santa Fe Island](https://expedia.co.uk/Santa-Fe-Island-Hotels.d6336630.Travel-Guide-Hotels)[Holiday Rentals in Santa Fe Island](https://expedia.co.uk/Santa-Fe-Island-Holiday-Rentals.d6336630.Travel-Guide-HolidayRentals)[Flights to Santa Fe Island](https://expedia.co.uk/Cheap-Flights-To-Santa-Fe-Island.d6336630.Travel-Guide-Flights)[Santa Fe Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe-Island.d6336630.Car-Hire-Guide)[Santa Fe Island Holidays](https://expedia.co.uk/Santa-Fe-Island.d6336630.Holidays-City-Breaks) ![Seal lions 😍 #aquatrove](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Elizabeth Oates # Compare and book 4 Star hotels in Santa Fe Island, Galápagos - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Fe Island 4 Star Hotels Tonight [8 Jan - 9 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2026-01-08&endDate=2026-01-09&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2026-01-09&endDate=2026-01-10&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2026-01-09&endDate=2026-01-11&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6336630&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Fe Island 4-star hotels ![Exterior](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/62b50762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/9ffdbf3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/926c680e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Double Room | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1870000/1862600/1862515/w2236h1687x0y0-81876455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Finch Bay Galapagos Hotel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) Puerto Ayora 9.4/10 Exceptional (91) "Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan £444 31 Jan - 1 Feb [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Finch-Bay-Galapagos-Hotel.h1862515.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/0a441130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, Terrace | View from room](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/62a98993.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/3a29c8f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/3b7f0639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cucuve [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) Puerto Ayora 10/10 Exceptional (269) "Wonderful staff, beautiful room, delicious breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley £180 5 Feb - 6 Feb [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) ![Breakfast, dinner served; local and international cuisine, sea views ](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/f2307f3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double or Twin Room | View from room](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/f92aa86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/a685ce77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Duplex | View from room](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/5dea777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ikala Galapagos Hotel [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (128) "Great staff—very helpful. Nice room and good location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/d5ba3cfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/a854801f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Signature | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/f83773fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blu Galapagos Sustainable Waterfront Lodge [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) Puerto Ayora 8.8/10 Excellent (122) "Beautiful property " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) David £187 14 Jan - 15 Jan [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Standard Double or Twin Room, 1 Bedroom | Free minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/10000000/9800000/9794800/9794727/faf80253.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/10000000/9800000/9794800/9794727/f34c4f73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Free minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/10000000/9800000/9794800/9794727/a21927f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9800000/9794800/9794727/f4f162b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Santa Fe [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Santa-Fe.h9794727.Hotel-Information) Puerto Ayora 9.6/10 Exceptional (14) "Beautiful hotel, with amazing staff, and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven £158 10 Jan - 11 Jan [](https://www.expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Santa-Fe.h9794727.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Santa-Fe-Island-Hotels.s40-0-d6336630.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Santa-Fe-Island-Hotels.s40-0-d6336630.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Fe Island. ![Galapagos and Beyond](https://images.trvl-media.com/lodging/100000000/99530000/99523000/99522986/5d3c0d78_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Galapagos and Beyond Indefatigable entre Duncan & Juan Puerto Ayora Galapagos [Get rates](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=99522986&PinnedHotelID=99522986&HadPinnedHotel=true®ionId=6336630) 10/10 Exceptional! (9 reviews) [](https://expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-And-Beyond.h99522986.Hotel-Information) Still don't see what you're looking for? [See all properties in Santa Fe Island.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6336630&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6336630&star=40&star=40&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6336630&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6336630&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6336630&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=6336630&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Santa Fe Island Marvel at dense forests of prickly pear, pose for a photo next to a sunbathing sea lion and spot endemic iguanas and rats. [See all hotels in Santa Fe Island](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-23&endDate=2026-01-24&adults=2®ionId=6336630) ![Seal lions 😍 #aquatrove](https://images.trvl-media.com/place/739209696364867584/ee8e9092-8f66-41b4-85f2-83b0747d957f.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) Photo by Elizabeth Oates ## Top Santa Fe Island Hotel Reviews ![Ikala Galapagos Hotel](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/ecbf00ed_y.jpg) ### Ikala Galapagos Hotel 10/10 Excellent "Great staff—very helpful. Nice room and good location." [](https://expedia.co.uk/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information) ![Blu Galapagos Sustainable Waterfront Lodge](https://images.trvl-media.com/lodging/3000000/2060000/2057800/2057779/92acdc7e_y.jpg) ### Blu Galapagos Sustainable Waterfront Lodge 10/10 Excellent "Beautiful property " [](https://expedia.co.uk/Puerto-Ayora-Hotels-Galapagos-Habitat-By-Eco-Luxury-Group.h2057779.Hotel-Information) ![Hotel Cucuve](https://images.trvl-media.com/lodging/14000000/13150000/13147200/13147131/733c9cb5_y.jpg) ### Hotel Cucuve 10/10 Excellent "Best place we stayed at in Ecuador. Clean, friendly and affordable. " [](https://expedia.co.uk/Puerto-Ayora-Hotels-Hotel-Cucuve.h13147131.Hotel-Information) ## Find out more about Santa Fe Island ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in Santa Fe Island? > - Search for the lowest price from £158 ### What's the difference between 5-star and 4-star hotels in Santa Fe Island? ### Does Santa Fe Island have any 4-star all-inclusive resorts? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in North Seymour Island ](https://www.expedia.co.uk/4Star-North-Seymour-Island-Hotels.s40-0-d6336659.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Seymour Island ](https://www.expedia.co.uk/5Star-North-Seymour-Island-Hotels.s50-0-d6336659.Travel-Guide-Filter-Hotels) - [Baltra Hotels ](https://www.expedia.co.uk/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Bellavista Hotels ](https://www.expedia.co.uk/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - 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(OAX) to San Cristobal (SCY) ](https://www.expedia.co.uk/lp/flights/oax/scy/oaxaca-intl-to-san-cristobal) - [Flights from Coca (OCC) to Isla Baltra (GPS) ](https://www.expedia.co.uk/lp/flights/occ/gps/coca-to-isla-baltra) - [Flights from Puerto Escondido (PXM) to San Cristobal (SCY) ](https://www.expedia.co.uk/lp/flights/pxm/scy/puerto-escondido-to-san-cristobal) - [Flights from Santiago (SCL) to Isla Baltra (GPS) ](https://www.expedia.co.uk/lp/flights/scl/gps/santiago-to-isla-baltra) - [Flights from Quito (UIO) to Isla Baltra (GPS) ](https://www.expedia.co.uk/lp/flights/uio/gps/quito-to-isla-baltra) - [Flights from Quito (UIO) to San Cristobal (SCY) ](https://www.expedia.co.uk/lp/flights/uio/scy/quito-to-san-cristobal) - [Baltra Holidays ](https://www.expedia.co.uk/Baltra.d6223000.Holidays-City-Breaks) - [Charles Darwin Research Station ](https://www.expedia.co.uk/Charles-Darwin-Research-Station-Galapagos.d6171312.Attraction) - [Visit El Cascajo ](https://www.expedia.co.uk/El-Cascajo.dx6222749) - [Galápagos Holidays ](https://www.expedia.co.uk/Galapagos.d1371.Holidays-City-Breaks) - [Visit Galápagos ](https://www.expedia.co.uk/Galapagos.dx1371) - [Visit North Seymour Island ](https://www.expedia.co.uk/North-Seymour-Island.dx6336659) - [Playa de los Alemanes ](https://www.expedia.co.uk/Playa-De-Los-Alemanes-Puerto-Ayora.d553248625325955800.Attraction) - [Puerto Ayora Holidays ](https://www.expedia.co.uk/Puerto-Ayora.d602686.Holidays-City-Breaks) - [Visit Puerto Ayora ](https://www.expedia.co.uk/Puerto-Ayora.dx602686) - [Puerto Baquerizo Moreno Holidays ](https://www.expedia.co.uk/Puerto-Baquerizo-Moreno.d6138894.Holidays-City-Breaks) - [Visit Puerto Baquerizo Moreno ](https://www.expedia.co.uk/Puerto-Baquerizo-Moreno.dx6138894) - [Santa Cruz Island Holidays ](https://www.expedia.co.uk/Santa-Cruz-Island.d6053670.Holidays-City-Breaks) - [Visit Santa Cruz Island ](https://www.expedia.co.uk/Santa-Cruz-Island.dx6053670) - [Visit Santa Rosa ](https://www.expedia.co.uk/Santa-Rosa.dx6053725) - [Tortuga Bay Beach ](https://www.expedia.co.uk/Tortuga-Bay-Beach-Bella-Vista.d6171324.Attraction) - [Yoga Holiday Packages Santa Cruz Island ](https://www.expedia.co.uk/lp/theme-holidays/yoga-holidays/6053670/Santa-Cruz-Island) - [Avis Rental Cars in North Seymour Island ](https://www.expedia.co.uk/Avis-Car-Rentals-In-North-Seymour-Island.d6336659-c41.Car-Rental-Guide-Suppliers) - [Car hire Puerto Ayora ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Puerto-Ayora.d602686.Car-Hire-Guide) - [Car hire near Santa Cruz Island ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz-Island.d6053670.Car-Hire-Guide) - [Rental cars Seymour airport ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Seymour.d6024439.Car-Hire-Guide) - [Car hire near Galápagos ](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Car-Hire-Destinations) - [Greenmotion Rental Cars in North Seymour Island ](https://www.expedia.co.uk/Greenmotion-Car-Rentals-In-North-Seymour-Island.d6336659-c1093.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in North Seymour Island ](https://www.expedia.co.uk/Thrifty-Car-Rental-Car-Rentals-In-North-Seymour-Island.d6336659-c45.Car-Rental-Guide-Suppliers) - [Top Rent a Car Rental Cars in Santa Cruz Island ](https://www.expedia.co.uk/Top-Rent-A-Car-Car-Rentals-In-Santa-Cruz-Island.d6053670-c1028.Car-Rental-Guide-Suppliers) - [Baltra Holiday Rentals ](https://www.expedia.co.uk/Baltra-Holiday-Rentals.d6223000.Travel-Guide-HolidayRentals) - [Bellavista Holiday Rentals ](https://www.expedia.co.uk/Bellavista-Holiday-Rentals.d6342722.Travel-Guide-HolidayRentals) - [Galápagos Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Holiday-Rental-Destinations) - [Santa Cruz Island Holiday Rentals ](https://www.expedia.co.uk/Santa-Cruz-Island-Holiday-Rentals.d6053670.Travel-Guide-HolidayRentals) - [Santa Rosa Holiday Rentals ](https://www.expedia.co.uk/Santa-Rosa-Holiday-Rentals.d6053725.Travel-Guide-HolidayRentals) - [Things to do in Baltra ](https://www.expedia.co.uk/Things-To-Do-In-Baltra.d6223000.Travel-Guide-Activities) - [Things to do in Galápagos ](https://www.expedia.co.uk/Things-To-Do-In-Galapagos.d1371.Travel-Guide-Activities) - [Things to do in North Seymour Island ](https://www.expedia.co.uk/Things-To-Do-In-North-Seymour-Island.d6336659.Travel-Guide-Activities) - [Things to do in Puerto Ayora ](https://www.expedia.co.uk/Things-To-Do-In-Puerto-Ayora.d602686.Travel-Guide-Activities) - [Things to do in Santa Cruz Island ](https://www.expedia.co.uk/Things-To-Do-In-Santa-Cruz-Island.d6053670.Travel-Guide-Activities)