Beginning of main content

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured San Luis Obispo 4 Star Hotels

See all 504 Hotels in San Luis Obispo
Madonna Inn

Madonna Inn

100 Madonna Road, San Luis Obispo
4.0 out of 5.0
4.2 out of 5 (1,192 reviews)
Large comfortable roomThe room was very good. The restaurant was horrible. Food was inferior and overpriced. Worst service I have ever experienced.
  13 Dec 2017

£150

£150
Historic Santa Maria Inn

Historic Santa Maria Inn

801 S Broadway, Santa Maria
4.0 out of 5.0
4.1 out of 5 (1,800 reviews)
Nothing went wrong over three days, which is saying a lot.
  13 Dec 2017

£60

£60
SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

2241 Price Street, Pismo Beach
4.0 out of 5.0
4.4 out of 5 (2,087 reviews)
Hotel on the beach!Beautiful hotel grounds, even though under construction. Right on the beach and a shower to rinse off! The room was comfortable for our family, 2 adults and 2 kids, but the sounds at night were bothersome. You could hear people running in the hallways and above our room, very disturbing when trying ...
  13 Dec 2017

£103

£103
Radisson Hotel Santa Maria

Radisson Hotel Santa Maria

3455 Skyway Dr, Santa Maria
4.0 out of 5.0
4.2 out of 5 (1,112 reviews)
Large roomsHotel is decent condition, comfortable and secure. Staff is friendly and proficient. Decent value for money
  16 Dec 2017

£78

£78
Inn at the Pier

Inn at the Pier

601 Cypress Street, Pismo Beach
4.5 out of 5.0
3.2 out of 5 (9 reviews)
Weekend Getaway!Booked the hotel without knowing the actual location and what a surprise that was. The hotel is located next to the Pier, top floor is overlooking the ocean, you are close to everything within a walking distance. And, not the last the hotel is brand new so everything is as new & modern as it can ...
  4 Dec 2017

£101

£101
La Bellasera Hotel And Suites

La Bellasera Hotel And Suites

206 Alexa Ct, Paso Robles
4.5 out of 5.0
4.5 out of 5 (946 reviews)
Lovely hotel in Paso RoblesThe hotel is very modern and clean. The restaurant is good, and the staff are courteous and easy to locate when needed. My only complaint, and it is minor, is that the floor in our room vibrated when the furnace was on. As long as we were in the bed, we couldn't feel it, but walking around, it was ...
  6 Dec 2017

£130

£130
Avila Lighthouse Suites

Avila Lighthouse Suites

550 Front St, Avila Beach
4.0 out of 5.0
4.6 out of 5 (647 reviews)
Great one night getawayOur night at Avila Light House Suites would have been perfect for our anniversary weekend, if the pool and hot tub were open. Apparently they were being renovated. The staff was able to upgrade our room to an ocean view suite! It was a great trade!
  11 Dec 2017

£129

£129
Inn At Morro Bay

Inn At Morro Bay

60 State Park Rd, Morro Bay
4.0 out of 5.0
3.7 out of 5 (2,031 reviews)
Very nice Hotel We have wanted to stay at this hotel for many years. We had a very nice room that looked over the pool. Nice little patio of the room. Easy walk to the marsh to bird watch and eat at the Bayside Cafe. We would stay there again.
  15 Dec 2017

£48

£48
Comfort Inn Downtown - Morro Bay

Comfort Inn Downtown - Morro Bay

590 Morro Ave, Morro Bay
4.0 out of 5.0
4.2 out of 5 (561 reviews)
New, fresh, clean, very nice staff, nice breakfast (included), affordable
  9 Dec 2017

£60

£60
Avila La Fonda Hotel

Avila La Fonda Hotel

101 San Miguel St, Avila Beach
4.5 out of 5.0
4.7 out of 5 (637 reviews)
Make Time to Enjoy La Fonda's HospitalityTucked away just a block from the beach and busy storefront, is one of Avilla's shining gems.. The La Fonda Hotel welcomes guests with all the warmth of a long-awaited home coming. Upon entering the spacious lobby of the Spanish-style hotel, you are immediately welcomed by staff that are friendly ...
  16 Dec 2017

£127

£127
Map

Pocket Guide: 4 Star Hotels in San Luis Obispo

Search for hotels in San Luis Obispo on Expedia.co.uk. You can easily find your hotels in San Luis Obispo using one of the methods below:

  • View our selection of featured hotels in San Luis Obispo
  • Use the map to find hotels in the San Luis Obispo neighborhood you prefer
  • Use the filters to see hotels in a specific area of San Luis Obispo, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in San Luis Obispo
  • Enter your travel dates to view the best deals on hotels in San Luis Obispo - while they last

Recently booked San Luis Obispo hotels

Embassy Suites by Hilton San Luis Obispo
3.5 out of 5.0
Last booking: 1 minute ago
Avenue Inn Downtown San Luis Obispo
3.0 out of 5.0
Last booking: 3 minutes ago
Paso Robles Inn
3.5 out of 5.0
Last booking: 14 minutes ago
Best Western Plus Black Oak
3.5 out of 5.0
Last booking: 28 minutes ago
Aloha Inn
2.5 out of 5.0
Last booking: 33 minutes ago
La Serena Inn
3.0 out of 5.0
Last booking: 34 minutes ago
Allegretto Vineyard Resort Paso Robles
5.0 out of 5.0
Last booking: 44 minutes ago
Cottage Inn By The Sea
3.5 out of 5.0
Last booking: 54 minutes ago
Best Western San Marcos Inn
3.0 out of 5.0
Last booking: 56 minutes ago