A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

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Check availability on Key Largo 4 Star Hotels

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

Our top choices for Key Largo 4-star hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.2 out of 10, Wonderful, (1,557 reviews)
"Beautiful property, great room, perfect location. Staff were amazing and very nice clean property! Restaurant was excellent"
Canada
William Dean
The price is £214
includes taxes & fees
2 Nov - 3 Nov
Reefhouse Resort & Marina
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.8 out of 10, Excellent, (1,200 reviews)
"Very relaxing the beach was nice and pretty from that side of the property clean rooms staff was nice and helpful they made the stay enjoyable"
United States
Damion
The price is £250
includes taxes & fees
12 Nov - 13 Nov
Baker's Cay Resort Key Largo, Curio Collection by Hilton
An aerial view of a resort with a large pool, palm trees, and a beach.

3. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
9.0 out of 10, Wonderful, (1,002 reviews)
"Everything was amazing!!! Beautiful hotel and great location."
United States
Jorge
The price is £262
includes taxes & fees
29 Nov - 30 Nov
Playa Largo Resort & Spa, Autograph Collection
A sunset over a body of water with clouds.

4. Condo in the Keys

Condo in the Keys
4.0 star property
Tavernier
8.2 out of 10, Very good, (17 reviews)
"Love the location "
United States
Angela
Condo in the Keys
A beachside patio with outdoor seating, palm trees, and a view of the marina.

5. Key Largo Condo - Community Pool, Marina & Beach!

Key Largo Condo - Community Pool, Marina & Beach!
4.0 star property
Key Largo
Key Largo Condo - Community Pool, Marina & Beach!
Balcony

6. The Sanctuary Islet by Florida Keys Luxury Rentals

The Sanctuary Islet by Florida Keys Luxury Rentals
4.0 star property
Key Largo
The Sanctuary Islet by Florida Keys Luxury Rentals
Exterior

7. Lime Key by Florida Keys Luxury Rentals

Lime Key by Florida Keys Luxury Rentals
4.0 star property
Buccaneer Point
Lime Key by Florida Keys Luxury Rentals
Pool

8. Coral Palm's Estate by Florida Keys Luxury Rentals

Coral Palm's Estate by Florida Keys Luxury Rentals
4.0 star property
Key Largo
Coral Palm's Estate by Florida Keys Luxury Rentals
Pool

9. Cukoos Nest by Florida Keys Luxury Rentals

Cukoos Nest by Florida Keys Luxury Rentals
4.0 star property
Winston Waterways
Cukoos Nest by Florida Keys Luxury Rentals
Pool

10. Bay Beach by Florida Keys Luxury Rentals

Bay Beach by Florida Keys Luxury Rentals
4.0 star property
Key Largo
Bay Beach by Florida Keys Luxury Rentals
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Learn more about Key Largo

The underwater paradise of John Pennekamp Coral Reef State Park offers the best snorkelling visibility before noon. Dive among colourful fish at America's first undersea park, then feast on fresh-caught grouper at waterfront restaurants where locals gather.

See all hotels in Key Largo
A wooden pier extending into calm waters, lined with palm trees and beach chairs.

Top Key Largo Hotel Reviews

Find out more about Key Largo

Frequently asked questions

What are the best 4-star hotels in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a 4-star hotel in Key Largo that's a favourite among Expedia guests. Concierge services and a resort are just a couple of its amenities. Travellers also love Bakers Cay Resort Key Largo, Curio Collection by Hilton. From private picnic options to a terrace, it offers conveniences that cater to every aspect of your enjoyment and relaxation.
How much does it cost to stay in a 4-star hotel in Key Largo?
With Expedia's sort and search filters, bagging a terrific deal on a 4-star hotel in Key Largo just got simpler. Start by keying in your chosen arrival date and length of your stay. Then list the results by price and choose a property that best matches your budget and style.

  • Search for the lowest price from £214

What's the difference between 5-star and 4-star hotels in Key Largo?
Give yourself the luxury treatment during your Key Largo holiday by checking in to a 4-star hotel. As well as featuring upscale accommodation, these properties are usually packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go above and beyond to make your trip an even more lavish and special one. 24-hour front desk, elegant furnishings and world-class dining are a few of the first-rate conveniences and services you'll likely be able to enjoy.