Does Big Pine Key have any 4-star all-inclusive resorts?

Finding your dream holiday in Big Pine Key is as easy as entering your travel dates and clicking on our "All inclusive" filter. Stay and play where just about everything is already taken care of like your accommodation, meals and activities, or go for a standard 4-star resort in or around this top destination.

Are there any 4-star casino hotels in Big Pine Key?

Shuffle between your room and the blackjack table with ease by using our handy filters to find 4-star casino hotels in and around Big Pine Key. Celebrating with someone special? Narrow your search further by choosing amenities with that wow-factor, like a view or hot tub.

The 10 Best 4 Star Hotels in Big Pine Key - 2026 Updated Prices

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Our top choices for Big Pine Key 4-star hotels

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Marathon

Kenier

includes taxes & fees

8 Jun - 9 Jun

Tranquility Bay Beachfront Hotel and Resort

Marathon

maybelis

includes taxes & fees

22 Jun - 23 Jun

Grassy Flats Resort & Beach Club

Marathon

Shonlyn

includes taxes & fees

3 Jun - 4 Jun

The Reef at Marathon, Florida Keys

Marathon

Ricardo

Marlin Bay Resort & Marina

Marathon

Chardell

Luxury Villa, 3 Bedrooms, Balcony, Overwater | Terrace/patio

Waterfront Luxury Villa

Marathon Shores

Indigo Reef Marina Pet Friendly Homes by Pack and Relax

Marathon

Indigo Reef Marina Homes Close to Boat Slip by Pack and Relax

Marathon Shores

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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Big Pine Key.

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL

£245

30 Jun - 1 Jul

includes taxes & fees

9.2/10 Wonderful! (1,163 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Big Pine Key

Snorkel crystal-clear waters teeming with colourful fish, then spot adorable Key deer at the National Key Deer Refuge. Unwind on pristine beaches like Calusa or Sandspur, where soft sand meets turquoise waves.

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Top Big Pine Key Hotel Reviews

Tranquility Bay Beachfront Hotel and Resort

8/10 Good

"The property location view is beautiful that is what you pay for, we stayed in the 2 bedroom villas and they are well past their prime and in need of a major update, everything is old, outdated and rundown. The adult pool needs new umbrellas ours broke while laying under it, things in the villa didn’t work and seemed like everything f was from the originally opening date but, too much to list just know that going in. The sunset views are stellar but, we won’t be back until it’s renovated."

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

6/10 Okay

"The location was okay, but not any place we'd revisit. There's a pool in the main lobby area and another that is where the rooms are. That one doesn't have pool service and this is the first resort that we've been to that doesn't have towels available at the pool. Unknowingly to us, there were towels in the cabinet but we never opened that. They have a coffee/snack bar that I was told closed at 11. I was really looking forward to an iced coffee and just thought it was strange that the hours weren't longer."

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Frequently asked questions

What are the best 4-star hotels in Big Pine Key?

Create unforgettable holiday memories in Big Pine Key at Little Palm Island Resort & Spa - A Noble House Resort. A favourite with our guests, this 4-star hotel offers loads of conveniences for a relaxing and comfortable stay.

How much does it cost to stay in a 4-star hotel in Big Pine Key?

To find a 4-star hotel in Big Pine Key that fits your budget, use Expedia's handy filters. Take a look at the available options during your holiday dates and use our pricing filter to set your limit. You can also list your results by the most budget-friendly stay first.

Search for the lowest price from £245

What's the difference between 5-star and 4-star hotels in Big Pine Key?

Treat yourself to luxury living during your Big Pine Key getaway by checking in to a 4-star hotel. As well as featuring upscale accommodation, these retreats are usually packed with amenities like large beds, complimentary bathrobes and plenty more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and unforgettable one. 24-hour concierge assistance, elegant furnishings and world-class dining are only the start of the exclusive services and conveniences you'll likely have access to.

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Our top choices for Big Pine Key 4-star hotels

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton