All Hotels by Independent in Sikeston - 2026 Updated Prices

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Top Sikeston Hotel Reviews

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent

"Excellent staff! Clean rooms!"

Hampton Inn Sikeston

8/10 Good

"Fast checking in and out. Very friendly staff and abundant complimentary breakfast. Spacious room and we liked having a walk in shower. There was plenty of green space to walk our small dog. The only complaint we had is that when we sat on the sofa, the cushion covers came off. They did not zip securely over the cushion anymore."

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Top Sikeston Hotel Reviews

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Sikeston, MO

Fairfield Inn & Suites by Marriott Sikeston

Hampton Inn Sikeston

Best Western Plus Sikeston I-55

Comfort Inn & Suites Sikeston I-55

Search Hotels by Independent in Sikeston

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Top Sikeston Hotel Reviews

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG