Santa Cruz Holidays

Book a Hotel + Flight or Car together to unlock savings

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    Save up to £195 when you book a flight and hotel together*
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Your Santa Cruz Holiday

Make organising your next getaway a breeze with a Santa Cruz holiday package. Whether it's history, nature or something else entirely that lures you here, our packages will help you experience the best of it. Planning an itinerary for your trip to Santa Cruz? Start with well-known cities like Colinas del Urubo, Samaipata and San Jose de Chiquitos. When it's time to stop dreaming and start packing, Expedia will help turn your Santa Cruz holiday into a reality.

Top destinations in Santa Cruz

San Lorenzo Cathedral showing a garden
FlightsFlightsHotelsHotels

Santa Cruz

Santa Cruz

Santa Cruz Essential Information

Language
Spanish
Currency
Bolivian bolivianos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Viru Viru Intl. Airport (VVI)
Top Sights
Santa Cruz Zoo, Amboró National Park and Lomas de Arena Regional Park

Our pick of the best Santa Cruz Hotel Deals

TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa Cruz
4 out of 5
Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz
Enjoy free Wi-Fi, breakfast (surcharge) and a fitness centre.
9.2/10 Wonderful! (76 reviews)
"We didn’t arrive until 5:00am and they kept our room available for our late arrival. Staff was A ! Highly recommend and will stay there again."

Reviewed on 12 May 2024

TRYP by Wyndham Santa Cruz
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
Enjoy free parking, a full-service spa and a rooftop terrace. Our guests praise the property condition in their reviews.
8.8/10 Excellent! (147 reviews)
"Clean comfortable room and beds. Nice fitness center. Small pool and hot tub could be hotter. Munimal vegan options at restaurant but lots of other places nearby."

Reviewed on 17 Apr 2024

Marriott Santa Cruz de la Sierra Hotel
Camino Real Hotel
Camino Real Hotel
4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
Book a stay at this luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ...
8.6/10 Excellent! (327 reviews)
Excelente!!!
"Excelente hotel, muy confortable. Lo único malo es que no se puede desayunar con la ropa que saldrás al trabajo, hay mucho olor a comida en el restaurante y se queda en la ropa."

Reviewed on 18 Apr 2024

Camino Real Hotel
See all 217 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Holidays

All Inclusive Holidays

Beach Holidays

Beach Holidays

Family Friendly Holidays

Family Friendly Holidays

Frequently asked questions

How much does a Santa Cruz travel package cost?
Handcraft your Santa Cruz package from just . Choose from any combination of hotels, flights and rental cars to craft the escape you’ve been dreaming of. Don’t forget to add on some activities and experiences!
If I'm not able to travel, can I cancel my Santa Cruz travel package?
Yes, you can. We realise even the best-laid plans can go awry, so we’re happy to help if you need to make changes to your Santa Cruz travel package. You may be able to cancel or change your itinerary at no cost if you’ve booked within 24 hours. Your hotel, airline or car rental company may charge you a fee if your booking was made more than 24 hours ago. Take a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the nitty-gritty on change fees.
How do I get a cheap travel package to Santa Cruz?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 air carriers and 1,000,000 hotels worldwide, your Santa Cruz travel package can be customized exactly to suit your travel style. With all those extra dollars, why not include a few exciting tours and experiences? It’s an easy way to unlock even more savings. Your dream getaway to Santa Cruz is much closer than you thought!
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Yes, we do. Expedia has joined forces with online lender Klarna to help you conveniently pay for your holiday in instalments. Simply pick the payment plan that works for you during checkout and take away the stress of budgeting for your trip. Make sure you bundle your flights, hotel and car hire with Expedia to get the biggest bang for your buck. Consider these flexible payment options below:

  • Pay monthly holidays: Escape on that dream holiday sooner with Klarna’s convenient monthly instalment plans. If paying a little each month works for you, choose this option during the checkout process.
  • Pay in instalments holidays: Into the idea of paying off your holiday in multiple transactions? Consider this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: Clicking the “book now” button is much easier with this payment option. Put down a small deposit on your booking and then start packing your suitcase.

What are the top hotels in Santa Cruz?
Camino Real Hotel and Sun Hotel know how to make their guests feel at home in Samaipata. If you also plan to stay in San Jose de Chiquitos, check out Camino Real Hotel and Sun Hotel. Both are popular with travellers.
How far in advance should I book my Santa Cruz holiday?
It’s tricky picking the ideal time for airfares, but we usually say the earlier, the better. Most international journeys on Expedia become available to compare up to 12 months in advance. If you’re booking last minute, fear not. Bargain prices occasionally appear within a few weeks of departure dates.
What does an Expedia Santa Cruz travel package include?
From flights and hotels to car rentals, Expedia can help you create a Santa Cruz package that’s ideal for you. Holidaying for a while? Look into a hotel, rental car and flight bundle. If you’re taking a quick break, a hotel and airfare deal could suit you better. Activities can also be added after you’ve booked. Our travel packages make it easy to plan and save.
What should I know before booking a Santa Cruz travel package?
A travel package can be more affordable than individually booking all you need for your trip. For example, combine your flights, hotels and rental cars and save a pretty penny. No matter your holiday goals, you’re bound to find a package to suit your budget.
Can I choose my airline with a Santa Cruz Expedia travel package?
Yes, you sure can. We have more than 550 airline partners globally, so pick the carrier that suits your travel preferences.

Discover the most popular places to visit in Santa Cruz

Image for Plaza 24 de Septiembre

Plaza 24 de Septiembre

The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.

Plaza 24 de Septiembre
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San Lorenzo Cathedral

One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.

San Lorenzo Cathedral
Image for Ventura Mall

Ventura Mall

4/5(1 review)

During your visit to Santa Cruz, you can enjoy retail therapy at Ventura Mall. Make some time to visit the cathedral while you're in the area.

Ventura Mall

Unmissable things to do in Santa Cruz

Image for Entrance To Our World

Entrance To Our World

£7
Per adult
Entrance To Our World
Image for Uyuni Salt Flat Experience for 4 Days

Uyuni Salt Flat Experience for 4 Days

£554
Per adult
Uyuni Salt Flat Experience for 4 Days
Image for Santa Cruz de la Sierra Self Guided Sherlock Murder Mystery Game

Santa Cruz de la Sierra Self Guided Sherlock Murder Mystery Game

£17
Per adult
Santa Cruz de la Sierra Self Guided Sherlock Murder Mystery Game
See all activities in Santa Cruz

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.