£424 Cheap Flights from Knoxville (TYS) to San Francisco (SFO)

Book with confidence

Compare flights from Knoxville to San Francisco easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Knoxville to San Francisco. Operating between them flights per day, 1 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from McGhee Tyson to San Francisco Intl..

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.

Grab a great deal on your flight from McGhee Tyson (TYS) to San Francisco Intl. (SFO)

The easiest way to view the best deals on flights from Knoxville to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from McGhee Tyson to San Francisco Intl. start at just £708 and range up to £961.

To find an even better deal, try

• being flexible on your dates – midweek flights can be cheaper
• looking for other airports near Knoxville and San Francisco
• booking your flight during November, the cheapest month on this route
• varying your flight times – early morning and late at night are sometimes cheaper

Why you should book your Knoxville to San Francisco flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from McGhee Tyson to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.

Frequently Asked Questions

How much is a flight from TYS to San Francisco Airport?

Round-trip tickets between Knoxville Airport and SFO start from £708. This price is based on fares advertised within the last 7 days on Expedia for flights departing within the next year — make your booking ASAP to avoid missing out. Prices and availability are subject to change. Additional terms apply.

Do I need to pay a cancellation fee if I cancel my flight from Knoxville Airport to San Francisco Intl. Airport (SFO)?

The majority of flights can be conveniently cancelled online, but whether or not you are charged a fee depends on your airline. If you do have to cancel your holiday, follow the easy instructions in the Customer Service Portal.

How do I find cheap flights from TYS to SFO that have flexible change policies?

Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for McGhee Tyson Airport (TYS) to San Francisco Intl. Airport (SFO) flights, you'll see a "no change fees" filter for you to select.

How far is the flight from TYS to San Francisco Airport?

The flight distance from Alcoa to San Francisco is 3,400 kilometres. Bring a drink, some snacks and an interesting book to read. Keep yourself entertained and the hours will zip by.

Which airlines fly direct from Knoxville Airport to San Francisco Airport?

There are no direct flights, so you'll have to make at least one stop between McGhee Tyson Airport (TYS) and San Francisco Airport. Take advantage of the layover time to stretch your legs and grab a coffee.

Are TYS to San Francisco Airport flight tickets cheaper when they're purchased at the last minute?

It is possible to get an awesome last-minute deal from TYS to San Francisco Intl. Airport (SFO), but it's also possible to miss out altogether! As many airlines release prices up to 12 months in advance, it's worth keeping an eye on fares early and being ready to book when you see a bargain. Expedia compares air carrier prices and updates flight deals frequently, so you can rest assured you're always seeing the latest offers.