Title: £458 Cheap Flights from Santiago to Brussels (SCL to BRU) - Expedia.co.uk ![](https://images.trvl-media.com/place/178241/ccd70fac-089f-4243-91b3-72fd772c4d15.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_flights_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £458 Cheap Flights from Santiago (SCL) to Brussels (BRU) [View £458 flight on Thu, 6 Nov 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:457.50&airProductToken=AQplCjAIyYQBEgMxMTgY0lggjBgopa78AjCYtPwCOFFAAFgBagVOT0JBR3IIUU9ONE5PQjcKMQjJhAESAzU5NxiMGCChpAEo5bX8AjD2tvwCOFFAAVgBagVOT0JBR3IIUU9ONE5PQjcSCggBEAEYASoCQkEYASIECAEQASgCKAMwDQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Santiago Intl. Airport (SCL) to Brussels Airport (BRU) - ![Iberia](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:bru,departure:15/10/2025TANYT&leg2=from:bru,to:scl,departure:22/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) - ![British Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_BA.svg) British Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:bru,departure:15/10/2025TANYT&leg2=from:bru,to:scl,departure:22/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"BA"}}]) - ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:bru,departure:15/10/2025TANYT&leg2=from:bru,to:scl,departure:22/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:bru,departure:15/10/2025TANYT&leg2=from:bru,to:scl,departure:22/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:bru,departure:15/10/2025TANYT&leg2=from:bru,to:scl,departure:22/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:bru,departure:15/10/2025TANYT&leg2=from:bru,to:scl,departure:22/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Air Canada](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AC.svg) Air Canada [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:bru,departure:15/10/2025TANYT&leg2=from:bru,to:scl,departure:22/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AC"}}]) - ## Plan, book, fly with confidence - ### Be in the know Get alerts if flight prices drop or rise\* - ### Book smarter Save up to 25% on select hotels after you book a flight\* - ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Santiago (SCL) to Brussels (BRU) Prices were available within the past 7 days and start at £458 for one-way flights and £648 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £648 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:647.30&airProductToken=AQplCjAIyYQBEgMxMTgY0lggjBgopa78AjCYtPwCOEFAAFgBagVCQVNJQ3IIQU9ONE5RQjcKMQjJhAESAzU5NxiMGCChpAEo5bX8AjD2tvwCOEFAAVgBagVCQVNJQ3IIQU9ONE5RQjcKZQoxCMmEARIDNjAwGKGkASCMGCjmmf4CMPea_gI4QUAAWAFqBUJBU0lDcghBT040TlFCNwowCMmEARIDMTE3GIwYINJYKOOd_gIwhKT-AjhBQAFYAWoFQkFTSUNyCEFPTjROUUI3EgoIAhABGAIqAklCGAEiBAgBEAEoAigDKAQwDQ) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £654 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:653.30&airProductToken=AQplCjAIyYQBEgMxMTgY0lggjBgopa78AjCYtPwCOEFAAFgBagVCQVNJQ3IIQU9ONE5RQjcKMQjJhAESAzYwMxiMGCChpAEo_rr8AjCPvPwCOEFAAVgBagVCQVNJQ3IIQU9ONE5RQjcKZQoxCMmEARIDNjAwGKGkASCMGCjmmf4CMPea_gI4QUAAWAFqBUJBU0lDcghBT040TlFCNwowCMmEARIDMTE3GIwYINJYKOOd_gIwhKT-AjhBQAFYAWoFQkFTSUNyCEFPTjROUUI3EgoIAhABGAIqAklCGAEiBAgBEAEoAigDKAQwDQ) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £737 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:736.30&airProductToken=AQpnCjEIyYQBEgMxMTgY0lggjBgopa78AjCYtPwCOEFAAFgBagZPUFRJTUFyCEFPTjROUU03CjIIyYQBEgM1OTcYjBggoaQBKOW1_AIw9rb8AjhBQAFYAWoGT1BUSU1BcghBT040TlFNNwpnCjIIyYQBEgM2MDAYoaQBIIwYKOaZ_gIw95r-AjhBQABYAWoGT1BUSU1BcghBT040TlFNNwoxCMmEARIDMTE3GIwYINJYKOOd_gIwhKT-AjhBQAFYAWoGT1BUSU1BcghBT040TlFNNxIKCAEQARgBKgJJQhgBIgQIARABKAIoAygEMA0) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £743 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:742.30&airProductToken=AQpnCjEIyYQBEgMxMTgY0lggjBgopa78AjCYtPwCOEFAAFgBagZPUFRJTUFyCEFPTjROUU03CjIIyYQBEgM2MDMYjBggoaQBKP66_AIwj7z8AjhBQAFYAWoGT1BUSU1BcghBT040TlFNNwpnCjIIyYQBEgM2MDAYoaQBIIwYKOaZ_gIw95r-AjhBQABYAWoGT1BUSU1BcghBT040TlFNNwoxCMmEARIDMTE3GIwYINJYKOOd_gIwhKT-AjhBQAFYAWoGT1BUSU1BcghBT040TlFNNxIKCAEQARgBKgJJQhgBIgQIARABKAIoAygEMA0) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £810 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:809.40&airProductToken=AQplCjAIyYQBEgMxMTgY0lggjBgopa78AjCYtPwCOEFAAFgBagVCQVNJQ3IIQU9ONE5RQjcKMQjJhAESAzU5NxiMGCChpAEo5bX8AjD2tvwCOEFAAVgBagVCQVNJQ3IIQU9ONE5RQjcKmgEKMgjCggESAzM5MRihpAEg64kBKMiZ_gIwk5r-AjhOQABYAWoFTk9CQUdyCE5OTDBOUUI3CjEIwoIBEgM0NjgY64kBIIwYKOOa_gIw-Zv-AjhOQAFYAWoFTk9CQUdyCE5OTDBOUUI3CjEIwoIBEgQ0Mjg5GIwYINJYKOOd_gIwhKT-AjhOQAFYAWoFTk9CQUdyCE5OTDBOUUI3EgoIARABGAEqAklCGAEiBAgBEAEoAigDKAQwAQ) ![Iberia](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/IB.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £811 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:810.30&airProductToken=AQphCi4IyYQBEgMxMTgY0lggjBgopa78AjCYtPwCOE9AAFgBagNCQUdyCE9PTjROUU03Ci8IyYQBEgM1OTcYjBggoaQBKOW1_AIw9rb8AjhPQAFYAWoDQkFHcghPT040TlFNNwphCi8IyYQBEgM2MDAYoaQBIIwYKOaZ_gIw95r-AjhPQABYAWoDQkFHcghPT040TlFNNwouCMmEARIDMTE3GIwYINJYKOOd_gIwhKT-AjhPQAFYAWoDQkFHcghPT040TlFNNxIKCAEQARgBKgJCQRgBIgQIARABKAIoAzAN) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £815 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:814.30&airProductToken=AQpjCi8IwoIBEgMyNTAY0lgg64kBKIKu_AIw3rT8AjhPQABYAWoDQkFHcghPREwwTlFNNwowCMKCARIDMzk2GOuJASChpAEoi7r8AjDWuvwCOE9AAVgBagNCQUdyCE9ETDBOUU03CmEKLwjJhAESAzYwMBihpAEgjBgo5pn-AjD3mv4COE9AAFgBagNCQUdyCE9PTjROUU03Ci4IyYQBEgMxMTcYjBgg0lgo453-AjCEpP4COE9AAVgBagNCQUdyCE9PTjROUU03EgoIARABGAEqAkJBGAEiBAgBEAEoAigDMA0) ![Air Canada](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AC.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £825 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:824.40&airProductToken=AQqgAQo0CMGGARIEMjkxMxjSWCDBMyjzqPwCMOWr_AI4TEAAWAFqCFNUQU5EQVJEcghMTEEzNUFURwoyCMGGARICOTkYwTMgmF0oqK38AjCpsPwCOExAAVgBaghTVEFOREFSRHIITExBMzVBVEcKNAjBhgESAzgzMhiYXSChpAEo8bH8AjCatfwCOExAAVgBaghTVEFOREFSRHIITExBMzVBVEcKoAEKNAjBhgESAzgzMxihpAEgmF0onJf-AjDtmv4COExAAFgBaghTVEFOREFSRHIITExBMzVBVEcKMgjBhgESAjk4GJhdIMEzKIag_gIwjKP-AjhMQAFYAWoIU1RBTkRBUkRyCExMQTM1QVRHCjQIwYYBEgQyOTEyGMEzINJYKP-j_gIw7Kb-AjhMQAFYAWoIU1RBTkRBUkRyCExMQTM1QVRHEgoIAhABGAIqAkFDGAEiBAgBEAEoAigDKAQwAQ) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £897 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:896.20&airProductToken=AQpoCjEIy5gBEgM3MDIY0lgggJMBKIeu_AIwjbb8AjhSQABYAWoFTElHSFRyCFJSTEZCSExBCjMIy5gBEgQxNzA3GICTASChpAEo07v8AjCAvPwCOExAAVgBagVMSUdIVHIIUlJMRkJITEESCggBEAEYASoCS0wYASIECAEQASgCKAMoBDAB) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Thu, 6 Nov - Thu, 27 Nov SCL Santiago BRU Brussels £925 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:SCL,to:BRU,departure:06/11/2025TANYT&leg2=from:BRU,to:SCL,departure:27/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:924.70&airProductToken=AQqUAQouCMyCARIDNjMyGNJYIKakASjvsPwCMN-y_AI4UUAAWAFqAlNMcghRRVRTTFc4QgowCMyCARIEODA4NBimpAEg64kBKKCz_AIwzbj8AjhRQAFYAWoCU0xyCFFFVFNMVzhCCjAI05wBEgQyMDk2GOuJASChpAEorrr8AjD0uvwCOFRAAVgBagJTTHIIUUVUU0xXOEISCggBEAEYASoCTEEYASIECAEQASgCKAQoBjAB) ## Frequently asked questions ### How much is a flight from SCL to Brussels - National Airport (BRU)? > The lowest price advertised for a round-trip journey from Nuevo Pudahuel Airport to BRU is £648. But you better act fast. This figure is based on fares available within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Santiago International Airport to BRU? > Most flights can be conveniently cancelled online, but whether or not you are charged a fee depends on your airline. If you do have to cancel your break, follow the instructions in the [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033). ### How do I find cheap flights from Nuevo Pudahuel Airport to BRU that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Santiago International Airport to BRU flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from Nuevo Pudahuel Airport to BRU? > The distance is around 11,900 kilometres, so fill your carry-on bag with everything you need to make your journey comfortable. Wondering what to take on board your Santiago to Zaventem flight? A travel pillow, earplugs and a sleep mask are a few essentials. ### Which airlines fly direct from SCL to BRU? > If you want to travel straight from Santiago International Airport to BRU, you'll need to book a flight with one or more stops. Unfortunately, there are no airlines that fly directly on this route. ### Are Santiago International Airport to BRU flight tickets cheaper when they're purchased at the last minute? > Flight prices from Nuevo Pudahuel Airport to Brussels - National Airport (BRU) are available up to a year prior to departure on Expedia. And although you may occasionally pick up great last-minute deal, it's not something you should bank on. Also, booking your flights well in advance means you'll have more options — and you can avoid ending up with the dreaded middle seat! We're always updating our fares to bring you the best bargains, so keep checking in for all the latest specials. ## Travel information | Origin airport | Arturo Merino Benitez | | --- | --- | | Destination airport | Brussels - National | | Return price | £647 | | Distance | 11834 km | ## Book with confidence ### Compare flights from Santiago to Brussels easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Santiago to Brussels. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Brussels - National in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Arturo Merino Benitez to Brussels - National.   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Arturo Merino Benitez (SCL) to Brussels - National (BRU) The easiest way to view the best deals on flights from Santiago to Brussels today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Arturo Merino Benitez to Brussels - National start at just £648 and range up to £925.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Santiago and Brussels - booking your flight during November, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Santiago to Brussels flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Arturo Merino Benitez to Brussels - National for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in Everberg](https://www.expedia.co.uk/4Star-Everberg-Hotels.s40-0-d6349543.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Zaventem](https://www.expedia.co.uk/5Star-Zaventem-Hotels.s50-0-d5191.Travel-Guide-Filter-Hotels) - [Bertem Hotels](https://www.expedia.co.uk/Bertem-Hotels.d6274795.Travel-Guide-Hotels) - [Cheap Hotels in Brussels](https://www.expedia.co.uk/Brussels-Hotels-Budget-Hotels.0-0-d178241-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Brussels](https://www.expedia.co.uk/Brussels-Hotels-Family-Friendly-Hotel.0-0-d178241-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Brussels Hotels](https://www.expedia.co.uk/Brussels-Hotels.d178241.Travel-Guide-Hotels) - [Buken Hotels](https://www.expedia.co.uk/Buken-Hotels.d6349620.Travel-Guide-Hotels) - 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[Things to do in Zaventem](https://www.expedia.co.uk/Things-To-Do-In-Zaventem.d5191.Travel-Guide-Activities) \*Available to Expedia members.