Title: Best Serviced Apartments in St. Charles 2026 | Expedia.co.uk [Hotels in St. Charles](https://expedia.co.uk/St-Charles-Hotels.d183431.Travel-Guide-Hotels)[Holiday Rentals in St. Charles](https://expedia.co.uk/St-Charles-Holiday-Rentals.d183431.Travel-Guide-HolidayRentals)[St. Charles Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-St-Charles.d183431.Car-Hire-Guide)[St. Charles Holidays](https://expedia.co.uk/St-Charles.d183431.Holidays-City-Breaks) ![St. Charles is a rural Community in South East Minnesota](https://images.trvl-media.com/place/183431/30533b3b-ce9f-42e7-b976-83514176ce7e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/183431/30533b3b-ce9f-42e7-b976-83514176ce7e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=183431&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [8 May - 10 May](https://www.expedia.co.uk/Hotel-Search?regionId=183431&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [5 Jun - 7 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=183431&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [3 Jul - 5 Jul](https://www.expedia.co.uk/Hotel-Search?regionId=183431&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for St. Charles apartments ![Smart TV](https://images.trvl-media.com/lodging/101000000/100160000/100154500/100154466/5936a429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/101000000/100160000/100154500/100154466/ca7a11da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100160000/100154500/100154466/92d1dfac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100160000/100154500/100154466/37bff302.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Big River Inn - 3 bedroom apartment in Alma [](https://www.expedia.co.uk/Alma-Hotels-River-View-Apartment-In-Alma-Atop-The-Big-River-Theatre-Free-Concert-Tickets.h100154466.Hotel-Information) Alma 8.8/10 Excellent (15 reviews) "Great place in the heart of Alma" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin B. £193 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Alma-Hotels-River-View-Apartment-In-Alma-Atop-The-Big-River-Theatre-Free-Concert-Tickets.h100154466.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/74000000/73530000/73529000/73528917/8cb5d594.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73530000/73529000/73528917/925c8acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/74000000/73530000/73529000/73528917/12ad9234.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/74000000/73530000/73529000/73528917/w4030h2532x0y0-b2e7da55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hygge House // A Cozy Guest House 15 min from Downtown [](https://www.expedia.co.uk/Rochester-Hotels-The-Hygge-House-A-Cozy-Guest-House-15-Min-From-Downtown.h73528917.Hotel-Information) Rochester 10/10 Exceptional (19 reviews) "Very clean and cozy spot. Stayed here to take my husband to Mayo and the drive was really easy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mady F. £223 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Rochester-Hotels-The-Hygge-House-A-Cozy-Guest-House-15-Min-From-Downtown.h73528917.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/10e83a4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/da041c63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/63c8ec1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101430000/101428100/101428059/5ce804eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic! [](https://www.expedia.co.uk/Rochester-Hotels-2-Bedroom-Oasis-5-Minutes-To-Mayo-Clinic.h101428059.Hotel-Information) Rochester 9.6/10 Exceptional (27 reviews) "This was a very clean and cozy property." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela O. £162 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Rochester-Hotels-2-Bedroom-Oasis-5-Minutes-To-Mayo-Clinic.h101428059.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/13771477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/1cb15748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/f6e66ebc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/57000000/56500000/56499100/56499019/364d4839.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers! [](https://www.expedia.co.uk/Rochester-Hotels-Studio-Suite-Free-Breakfast-Shared-Pool-Hot-Tub-Great-For-Business-Travelers.h56499019.Hotel-Information) Rochester 8.6/10 Excellent (4 reviews) "Very nice and convenient stay. Everything we needed and extremely well maintained room and kitchen. Loved it and the responsiveness out our hosts!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick H. £127 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Studio-Suite-Free-Breakfast-Shared-Pool-Hot-Tub-Great-For-Business-Travelers.h56499019.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/127000000/126430000/126429200/126429186/c8d7b8d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/127000000/126430000/126429200/126429186/1500ebf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![WiFi, bed sheets](https://images.trvl-media.com/lodging/127000000/126430000/126429200/126429186/536705ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/127000000/126430000/126429200/126429186/afb4e709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Valley Farm Apartment [](https://www.expedia.co.uk/Spring-Valley-Hotels-Valley-Farm-Apartment.h126429186.Hotel-Information) Spring Valley £127 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Spring-Valley-Hotels-Valley-Farm-Apartment.h126429186.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/c10ebe66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/2a592498.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/18f935fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/102000000/101170000/101161700/101161628/62dcfb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Restful Haven-5 Minutes to Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-5-Star-Restful-Haven-5-Minutes-To-Mayo-Clinic.h101161628.Hotel-Information) Rochester 10/10 Exceptional (9 reviews) "It was amazing stay, it was very comfy, welcoming and definitely something we would book again!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica Z. £217 includes taxes & fees 18 Mar - 19 Mar [](https://www.expedia.co.uk/Rochester-Hotels-5-Star-Restful-Haven-5-Minutes-To-Mayo-Clinic.h101161628.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/112000000/111290000/111284700/111284608/26025d59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111290000/111284700/111284608/c10914f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111290000/111284700/111284608/c22c98da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111290000/111284700/111284608/48fb1f69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom apartment in delightful Rochester with WiFi, AC [](https://www.expedia.co.uk/Rochester-Hotels-Charming-2-Bedroom-Apartment-In-Delightful-Rochester-With-WiFi.h111284608.Hotel-Information) Meadow Park 10/10 Exceptional (1 review) "Quiet, clean and in a friendly neighborhood. Staying there took some of the stress out of my Mayo Clinic visits. I always worry about my follow-up visits, but a good quiet place to stay helps me let that go." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria L E. £153 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Charming-2-Bedroom-Apartment-In-Delightful-Rochester-With-WiFi.h111284608.Hotel-Information) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/103000000/102170000/102161300/102161201/d5eba066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102170000/102161300/102161201/4d110927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102170000/102161300/102161201/e6f79fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/103000000/102170000/102161300/102161201/923b3799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The June // A one bedroom basement apartment, 3 mi to Mayo Clinic [](https://www.expedia.co.uk/Rochester-Hotels-The-June-A-One-Bedroom-Basement-Apartment.h102161201.Hotel-Information) Rochester 10/10 Exceptional (5 reviews) "This place was quiet, comfortable, well-stocked, and incredibly close to everything we were looking for. The hosts were great communicators, and accessing the place was a snap." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Josh P. £147 includes taxes & fees 18 Mar - 19 Mar [](https://www.expedia.co.uk/Rochester-Hotels-The-June-A-One-Bedroom-Basement-Apartment.h102161201.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/110000000/109300000/109297600/109297589/19ca23fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109300000/109297600/109297589/b54f44a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/110000000/109300000/109297600/109297589/67d4bcb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109300000/109297600/109297589/86ca9a78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Gwen // Charming 2-bedroom upstairs apartment in quiet duplex [](https://www.expedia.co.uk/Rochester-Hotels-The-Gwen-Charming-2-Bedroom-Upstairs-Apartment-In-Quiet-Duplex.h109297589.Hotel-Information) Rochester 9.6/10 Exceptional (4 reviews) "We loved staying at the Gwen! It’s located in a quiet neighborhood. We really appreciate the panoramic views out the windows in the cozy living room. The king beds were awesome and it’s so nice to be able to bring our pup!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Haley W. £218 includes taxes & fees 19 Mar - 20 Mar [](https://www.expedia.co.uk/Rochester-Hotels-The-Gwen-Charming-2-Bedroom-Upstairs-Apartment-In-Quiet-Duplex.h109297589.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/95000000/94900000/94898000/94897917/w508h683x258y0-95b6295b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/95000000/94900000/94898000/94897917/w902h683x61y0-66330067.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/95000000/94900000/94898000/94897917/28ed5186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/95000000/94900000/94898000/94897917/w903h683x60y0-0828c3f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private 2BR Entire Main Floor Unit Step to Mayo Clinic 518A [](https://www.expedia.co.uk/Rochester-Hotels-Next-To-Mayo-Clinic-518A.h94897917.Hotel-Information) Historic Southwest 9.8/10 Exceptional (25 reviews) "It was a perfect place for us to stay when going back & forth to Mayo. So well stocked, clean, comfortable and great communication with host. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherie T. £191 includes taxes & fees 14 Mar - 15 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Next-To-Mayo-Clinic-518A.h94897917.Hotel-Information) ![Two-Bedroom Apartment - Mobility Accessible/Non-Smoking | In-room safe, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/8523d385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/fa38f94a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/4cb3352e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/14000000/13180000/13173700/13173672/a8a8ab63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Broadway Plaza, Trademark Collection by Wyndham [](https://www.expedia.co.uk/Rochester-Hotels-Broadway-Plaza.h13173672.Hotel-Information) Downtown Rochester 9.2/10 Wonderful (174 reviews) "As always excellent staff, clean and comfortable rooms. Great central location. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Anita £154 includes taxes & fees 21 Mar - 22 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Broadway-Plaza.h13173672.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/122000000/121280000/121274700/121274625/090906e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/122000000/121280000/121274700/121274625/4296c205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/122000000/121280000/121274700/121274625/5e140052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121280000/121274700/121274625/d8495507.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Large and Rare 1-Bedroom Retreat with Gym, Bar, Pool & More –Pet-FriendlyOptions [](https://www.expedia.co.uk/Rochester-Hotels-Charming-1-Bedroom-Apartment-With-Fitness-Room-And-Kitchen-In-Lovely-Rochester.h121274625.Hotel-Information) Rochester £131 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Charming-1-Bedroom-Apartment-With-Fitness-Room-And-Kitchen-In-Lovely-Rochester.h121274625.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/57000000/56500000/56499000/56498935/f8464f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/57000000/56500000/56499000/56498935/f957f53a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/57000000/56500000/56499000/56498935/2058ca05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/57000000/56500000/56499000/56498935/ad1f7007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Free Breakfast. Pool & Hot Tub. Close to Mayo Clinic! Great for Business Travelers! [](https://www.expedia.co.uk/Rochester-Hotels-Free-Breakfast-Pool-Hot-Tub-Close-To-Mayo-Clinic-Great-For-Business-Travelers.h56498935.Hotel-Information) Rochester £120 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Free-Breakfast-Pool-Hot-Tub-Close-To-Mayo-Clinic-Great-For-Business-Travelers.h56498935.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/57000000/56500000/56499000/56498983/004bf825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player, offices](https://images.trvl-media.com/lodging/57000000/56500000/56499000/56498983/c6251052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/57000000/56500000/56499000/56498983/ed1e80b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/57000000/56500000/56499000/56498983/b09accd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio Suite | Free Breakfast + Pool & Hot Tub + Near Mayo Clinic! [](https://www.expedia.co.uk/Rochester-Hotels-Studio-Suite-Free-Breakfast-Pool-Hot-Tub-Near-Mayo-Clinic.h56498983.Hotel-Information) Rochester £119 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Rochester-Hotels-Studio-Suite-Free-Breakfast-Pool-Hot-Tub-Near-Mayo-Clinic.h56498983.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-27&endDate=2026-03-28®ionId=183431&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AA_SPRING_PROMO_183431) ## Find holiday rentals that suit your style Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America®ionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=CABIN) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America®ionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=VACATION_HOME) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America®ionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=APART_HOTEL) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America®ionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=COTTAGE) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America®ionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=APARTMENT) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America®ionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=VILLA) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Minnesota%2C+United+States+of+America®ionId=183431&latLong=44.000105%2C-92.052806&adults=2&startDate=2026-06-11&d1=2026-06-11&endDate=2026-06-14&d2=2026-06-14&lodging=CONDO) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSt-Charles-Apartments.d183431-aaApartments.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSt-Charles-Apartments.d183431-aaApartments.Travel-Guide-Accommodation) ## Top St. Charles Hotel Reviews ![Home2 Suites by Hilton Rochester Mayo Clinic Area](https://images.trvl-media.com/lodging/24000000/23520000/23512700/23512633/444e106b_y.jpg) ### Home2 Suites by Hilton Rochester Mayo Clinic Area 2/10 Terrible "The air conditioner let in air from outside. Thwre was a breeze about 10 mph and it blew in theoughb the ac and whistled all night long no sleep" [](https://expedia.co.uk/Rochester-Hotels-Home2-Suites-By-Hilton-Rochester-Mayo-Clinic-Area.h23512633.Hotel-Information) ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/404886d5_y.jpg) ### Aspen Suites 10/10 Excellent "Thé room was clean. Staff was nice. Super convenient location, and evening social was nice." [](https://expedia.co.uk/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Good place to stay " [](https://expedia.co.uk/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Hyatt House Rochester/Mayo Clinic Area](https://images.trvl-media.com/lodging/57000000/56840000/56833100/56833067/369065b1_y.jpg) ### Hyatt House Rochester/Mayo Clinic Area 10/10 Excellent "Staff is so kind and the location is do close. " [](https://expedia.co.uk/Rochester-Hotels-Hyatt-House-RochesterMayo-Clinic.h56833067.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "The room was clean and quiet. " [](https://expedia.co.uk/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/1062bbaa_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Not enought words of how wonderful my stay was! Thank you!" [](https://expedia.co.uk/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/c73455d9_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "Rooms were clean, plenty of tasty breakfast options, staff members were very nice, pool and hot tub area were clean and warm." [](https://expedia.co.uk/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 10/10 Excellent "Very nice place to stay at and very close to the mayo clinic " [](https://expedia.co.uk/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/edb11216_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 10/10 Excellent "breakfast is awesome- staff is very friendly and understanding of Mayo Clinic's goings on!!" [](https://expedia.co.uk/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ## Find out more about St. Charles ## St. Charles Apartments information | Number of reviews | 109 | | ----------------- | ------------- | | Accommodation | 78 Apartments | | Lowest Price | £106 | | Highest Price | £223 | ## Frequently asked questions ### What's it like to stay at an apartment in St. Charles? ### Are you thinking about an apartment instead of a traditional hotel? ### What's a favourite apartment for my stay in St. Charles? ### What can I expect from the weather in St. Charles? ### What should I see in St. Charles? ### What's the best way to get to and around St. Charles? ## Explore a world of travel with Expedia - More ways to book - [Book Apartments in St. Charles on Expedia.com ](https://www.expedia.com/St-Charles-Apartments.d183431-aaApartments.Travel-Guide-Accommodation)