Agathonisi Holidays from £332

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Your Agathonisi Holiday

Entertainment, history, art and more … It's all waiting for you with a Agathonisi holiday package. And with the ability to easily customise your city getaway, you know it'll be one that's tough to forget. Fill your trip to Agathonisi with tours of its big-ticket attractions. First stop? Make it Tsankári. A few quick clicks is all it takes to craft a customised Agathonisi holiday on Expedia.

Top Agathonisi Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
So Nice Hotel

So Nice Hotel

Save 100% on your flight
£332
per person
28 Sept - 5 Oct
found 24 hours ago
Return flight included
London (STN) to Samos (SMI)
9.4/10 Exceptional! (31 reviews)
I'm a young lady travelling alone and was a bit nervous about finding the right place to stay in Samos, but So Nice Hotel exceeded my expectations! Here are some of the things I appreciated about my stay: -I had some questions and booking adjustments to make with them before I arrived, and their responses were quick and helpful. -They were kind enough a taxi to receive me at the airport which followed through even after a last-minute layover. -The room was clean and tidy with a small kitchen that made it possible to cook simple meals with ingredients from the market just a few minutes walk away. -The hotel is a small building operated by just a few people, all who were welcoming and kind. -The room had air conditioning! -Just down the road there are lots of shops and restaurants with beach access and sitting areas that are either complimentary or accessible for a small charge. (Tortuga was my favorite place right on the beach and Green Zone which is just across from the beach was my favorite place overall). -I felt totally safe and was confident that the So Nice staff would be willing to help me with any confusion or complications I may have. If I ever return to Samos, this place would be my first choice!

Reviewed on 1 Aug 2025

Hydrele Beach Hotel

Hydrele Beach Hotel

£530
per person
28 Sept - 5 Oct
found 24 hours ago
Return flight included
London (STN) to Samos (SMI)
8.2/10 Very good! (69 reviews)
Huge ocean view room with two bathrooms. Very professional and polite staff.

Reviewed on 16 Aug 2026

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

£733
per person
26 Sept - 1 Oct
found 19 hours ago
Return flight included
London (LON) to Samos (SMI)
No reviews
Doryssa Boutique Hotel

Doryssa Boutique Hotel

£632
per person
28 Sept - 5 Oct
found 24 hours ago
Return flight included
London (STN) to Samos (SMI)
8.8/10 Excellent! (26 reviews)
The staff really make this hotel. Attentive, friendly and an absolute joy. Thank you for an amazing stay!

Reviewed on 30 Jul 2026

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

£684
per person
28 Sept - 5 Oct
found 24 hours ago
Return flight included
London (STN) to Samos (SMI)
9.4/10 Exceptional! (108 reviews)
Inner architecture is not good, rooms are good and clean, staff are really nice and helpful. I bought sea view room but it was not that much sea view it was more like concrete view, Beach and pool side are quite nice Breakfast was very good

Reviewed on 13 Aug 2026

Agathonisi Essential Information

Language
Greek
Currency
Euros
Local Welcome
Ya su
Local Goodbye
Yiá sou
Closest Airport
Samos Intl. Airport (SMI)
Max Temp Winter
13ºC
Max Temp Summer
27ºC

Top hotels in Agathonisi

Casa Cook Samos

Casa Cook Samos

Potokaki, Pythagorion Samos
Fully refundableReserve now, pay when you stay
£274
24 Sept - 25 Sept
includes taxes & fees
9.6/10 Exceptional! (133 reviews)
"Great hotel in a beautiful location! The beach is really the highlight! Beach view rooms are def the ones to pick. Breakfast has room for improvement."

Reviewed on 25 Aug 2026

Casa Cook Samos
Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

Pythagorion Samos Samos Island
£177
30 Aug - 31 Aug
includes taxes & fees
9.4/10 Exceptional! (108 reviews)
"Inner architecture is not good, rooms are good and clean, staff are really nice and helpful. I bought sea view room but it was not that much sea view it was more like concrete view, Beach and pool side are quite nice Breakfast was very good"

Reviewed on 13 Aug 2026

Proteas Blu Resort - Adults Only
Hydrele Beach Hotel

Hydrele Beach Hotel

Potokaki beach, Pythagorion Samos Samos island
£122
10 Sept - 11 Sept
includes taxes & fees
8.2/10 Very good! (69 reviews)
"Huge ocean view room with two bathrooms. Very professional and polite staff."

Reviewed on 16 Aug 2026

Hydrele Beach Hotel
See all 158 properties in Agathonisi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Agathonisi attractions

Pálos

Why not spend a lazy afternoon at Pálos during your trip to Agathonisi?
See properties

Spiliá

Why not spend a lazy afternoon at Spiliá during your trip to Agathonisi?
See properties

Tsankári

Why not spend a lazy afternoon at Tsankári during your trip to Agathonisi?
See properties

Vathý Pigádi

Why not spend a lazy afternoon at Vathý Pigádi during your trip to Agathonisi?
See properties

Gadourólakkos

Why not spend a lazy afternoon at Gadourólakkos during your trip to Agathonisi?
See properties

Frequently asked questions

Why should I book my Agathonisi holiday with Expedia?
With exceptional-value airfares, car hire and accommodation choices all in one place, Expedia makes arranging your Agathonisi getaway a cinch. Plus, we can help you bundle your bookings into a package holiday so you can save even more. Pick from amazing escapes, add your flights and/or a car hire (and maybe also some exciting activities!) and get incredible prices. Want to change your plans? Expedia has a flexible cancellation policy for many bookings. To learn more, visit our Customer Service Portal link.
When is the best time of year to holiday in Agathonisi?
Agathonisi can get very busy in January, May and July, so if you want to steer clear of the crowds, pack your bags for February, October and December. With average daytime temperatures of 11ºC, January is the coolest period in Agathonisi. The warmest time of year is July, when you can expect average temperatures of 26ºC during the day. Whatever the weather conditions, you'll discover plenty of things to keep you entertained here.
What is the top hotel for my holiday in Agathonisi?
Offering plenty of amenities and home comforts, Hotel Plaza will make the perfect base for your Agathonisi getaway.
How do I get a cheap holiday to Agathonisi?
Browse and lock in everything all in one place with our Agathonisi holidays. We have incredible bargains on flights, hotels, tours and more that'll keep your credit card happy and your adventurous spirit alive. And, with more than 400 air carriers and 321,000 properties around the globe to choose from, there are endless opportunities to mix and match as you want. Learn more about how you can save money on your next holiday when you bundle your flight and hotel bookings with Expedia.
What should I do on my Agathonisi holiday?
Make sure your next holiday in Agathonisi is a memorable one by checking out its leading attractions. Tsankári, Vathý Pigádi, Pálos and Spiliá are some of the things you should see while you're in the area.
What is the best area to stay in when on holiday in Agathonisi?
Agathonisi has a number of fascinating places to explore, such as Tsankári. Stay someplace nearby and make sightseeing easier.
Do I need a visa for my Agathonisi holiday?
Official government websites will have all the information you need on visa requirements, application procedures and any supporting documentation. Your nationality and reason for visiting, whether it be for work or pleasure, will determine if you need a visa for Agathonisi. Also be sure that your passport is up to date and has a minimum of six months validity remaining beyond your planned date of return. Finalise all your travel planning well ahead of time to avoid any nasty last-minute surprises.
What should I wear on my Agathonisi holiday?
Think about the types of activities you'll be doing during your Agathonisi trip and travel with pieces that you can mix and match. For fashion inspiration or even information on dress codes, browse style blogs or social media accounts. Pack appropriately by looking up the local weather conditions in Agathonisi. July brings the warmest temperatures, with daily averages of 26ºC, while January days average 11ºC, making it the coolest month.
What does an Expedia Agathonisi holiday include?
Much of that is up to you. Simply choose from a variety of Agathonisi bundles, such as a hire car, flight and hotel. You can also book a flight and a hotel, or a flight and a car hire. Once you've made your booking, add on the fun stuff like activities and experiences. Whatever your ideal Agathonisi holiday looks like, you're sure to save! Enjoy the flexibility and freedom to plan your holiday the way you want with Expedia.
Does Expedia offer Book Now, Pay Later Agathonisi holidays?
Expedia has partnered with online lender Klarna to make your next trip easier on your wallet. Paying in instalments means you can spread the costs of your next dream escape, leaving you with more money to spend while you're away. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Check out these flexible payment options:
  • Pay monthly holidays: If paying in multiple transactions sounds right for you, Klarna offers just that! Paying in multiple instalments will make that dream holiday possible.
  • No-deposit holidays: When you spot an awesome deal but your budget doesn't quite cover it yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to lock it in.
Can I choose my airline with an Agathonisi Expedia holiday?
Yes — that's the beauty of an Expedia package. You get to choose. We have access to more than 400 partner airlines all over the world, so you have lots of choice when planning your Agathonisi escape.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.