Title: Cayos Zapatilla Adventure Holidays 2026 | Expedia.co.uk ![](https://images.trvl-media.com/place/6246124/962b07b0-9b6f-43f9-a3da-ab98125d9cc6.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Cayos Zapatilla Adventure Holidays ## Book a Adventure Hotel + Flight or Car together to unlock savings Photo by Isa - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top flight + Adventure hotel deals in Cayos Zapatilla Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista £538 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) The room was clean, the staff was very polite/ friendly. Any concerns or requests were dealt with and the time spent was without an issue. Reviewed on 21 Dec 2025 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo £678 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Everything was great, food, service location. But the bed was abit lumpy. Reviewed on 22 Dec 2025 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco £661 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Big rooms, excellent food choices Reviewed on 20 Dec 2025 ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dreams Playa Bonita Panama - All Inclusive £811 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 7.4/10 Good! (1,002 reviews) Beautiful and luxurious Reviewed on 21 Dec 2025 ![Riande Aeropuerto Hotel & Casino](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Riande Aeropuerto Hotel & Casino £567 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 8.6/10 Excellent! (1,884 reviews) The room was impeccable, staff was awesome and very professional!!! Reviewed on 21 Dec 2025 Don't see what you're looking for? See all available trips from Quito to Cayos Zapatilla [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-22/2026-01-29/?FromAirport=UIO&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Adventure holidays in Cayos Zapatilla Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista £538 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) The room was clean, the staff was very polite/ friendly. Any concerns or requests were dealt with and the time spent was without an issue. Reviewed on 21 Dec 2025 ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Waldorf Astoria Panama Bella Vista £682 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 9/10 Wonderful! (1,001 reviews) Our room’s water heater was not working. We called and the technician came and said the water heater was not large enough. They hadn’t replace the water heater in our room. I don’t know why they put us in that room when the water heater wasn’t fully working. they said the rooms were sold out. The room was not vacuumed. They were peanuts on the carpet since we arrived. They were never picked up. We were in the hotel for six nights the gym. The carpet was super dusty and they were pieces of paper they weren’t picked up for days I complained about the gym that it’s not clean enough. They said it’s because it’s gonna be remodeled. This hotel should not be called at Waldorf Astoria. The people tried to be helpful, but nothing was done. I wouldn’t stay there again. Reviewed on 13 Dec 2025 ![The Westin Playa Bonita Panama](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Westin Playa Bonita Panama £733 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 8/10 Very Good! (1,000 reviews) Great place and location, excellent food choices! Reviewed on 20 Dec 2025 Don't see what you're looking for? See all available trips from Quito to Cayos Zapatilla [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-22/2026-01-29/?FromAirport=UIO&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Adventure holidays in Cayos Zapatilla Price found within the past 48 hours. Click for updated prices. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Riu Plaza Panama Bella Vista £538 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 9/10 Wonderful! (4,515 reviews) The room was clean, the staff was very polite/ friendly. Any concerns or requests were dealt with and the time spent was without an issue. Reviewed on 21 Dec 2025 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo £678 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) Everything was great, food, service location. But the bed was abit lumpy. Reviewed on 22 Dec 2025 ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco £661 per person 26 Jan - 29 Jan found 5 hours ago Return flight included Quito (UIO) to Panama City (PTY) 8.4/10 Very Good! (1,204 reviews) Big rooms, excellent food choices Reviewed on 20 Dec 2025 Don't see what you're looking for? See all available trips from Quito to Cayos Zapatilla [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-22/2026-01-29/?FromAirport=UIO&Destination=PAC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## More holidays you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holiday packages](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## More Holiday Ideas [Flights to Cayos Zapatilla ](https://expedia.co.uk/Cheap-Flights-To-Cayos-Zapatilla.d6286134.Travel-Guide-Flights)[ Cayos Zapatilla Hotels ](https://expedia.co.uk/Cayos-Zapatilla-Hotels.d6286134.Travel-Guide-Hotels)[ Cayos Zapatilla Holiday Rentals ](https://expedia.co.uk/Cayos-Zapatilla-Holiday-Rentals.d6286134.Travel-Guide-HolidayRentals)[ Cayos Zapatilla Car Hire ](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Cayos-Zapatilla.d6286134.Car-Hire-Guide)[ Cayos Zapatilla Holidays ](https://expedia.co.uk/Cayos-Zapatilla.d6286134.Holidays-City-Breaks) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app