Southeast Missouri Adventure Holidays

Book a Adventure Hotel + Flight or Car together to unlock savings

Photo by JG Morris
  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Top Adventure Southeast Missouri Hotels

Hampton Inn Farmington

Hampton Inn Farmington

2.5 out of 5
850 Valley Creek Dr Farmington MO
  • 2 hours drive from Mark Twain National Forest
Stay at this hotel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
8.8/10 Excellent! (551 reviews)
My mattress was broke and they didn't fix it. I asked for a replacement or to be switched to a diffrent room. They said they didn't have one available. I then got back to my room the second night and they texted me at 11:48 and said they could swith rooms after I was already asleep in the floor for ...

Reviewed on 1 May 2026

Hampton Inn Farmington
Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection

2.5 out of 5
4245 Hunt Rd Farmington MO
  • 2 hours drive from Mark Twain National Forest
Stay at this golf hotel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (619 reviews)
Clean and nice staff

Reviewed on 6 May 2026

Crown Pointe Lodge, BW Signature Collection
Echo Bluff State Park

Echo Bluff State Park

2.5 out of 5
34489 Echo Bluff Dr Eminence MO
  • 43 min drive from Mark Twain National Forest
Stay at this business-friendly hotel in Eminence. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Echo Bluff State Park and Current ...
9.4/10 Exceptional! (249 reviews)
Property was clean, quiet and beautiful. The restaurant is not worth it what so ever. 18$ nachos with 3 little chunks of chicken and a couple pieces of jalepeno. We decided after that to not order entrees. Our room was clean and very cozy. Staff was extremely nice.

Reviewed on 9 May 2026

Echo Bluff State Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More holidays you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.