Title: Panama Canal Zone Adults Only Holidays 2025/2026 | Expedia.co.uk ![](https://images.trvl-media.com/place/6222968/39ce6d2b-8d2b-450a-ae23-c66141215f6c.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Panama Canal Zone Adults Only Holidays ## Book a Adults Only Hotel + Flight or Car together to unlock savings Stay added Flight added Car - Economy - Premium economy - Business class - First class Leaving from Going to Dates Travellers ## Room 1 Adults ChildrenAges 2 to 17 InfantsYounger than 2 I only need accommodation for part of my trip - ## Plan, book, travel with confidence ### Better together Save up to £335 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Packages with flights are ATOL protected ## Top flight + Adults Only hotel deals in Panama Canal Zone Price found within the past 48 hours. Click for updated prices. ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco £810 per person 24 Dec - 29 Dec found 1 day ago Return flight included Port of Spain (POS) to Panama City (PTY) 8.4/10 Very Good! (1,127 reviews) Absolutely amazing property. 10/10 recommendations from me. Worth the stay. Reviewed on 15 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=91995575&paandie=true&HotelClass=40&dealMarker=yuypA8-xtriqmYgFhS2JQeTAtNhsJpTnbO43VtS8wJyaH297QfS9YKtZICqsjCvn) ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo Save 100% on your flight £1,154 per person 24 Dec - 29 Dec found 1 day ago Return flight included Port of Spain (POS) to Panama City (PTY) 9/10 Wonderful! (1,005 reviews) perfect location and city. Only comment is the supervisor, a short gentleman, is very aggressive and rude. Shoutout to Barbara, Rene and Jose. Reviewed on 21 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=15683502&paandie=true&HotelClass=40&dealMarker=q5c9I7v4G9PbtUuIK1vwcDZTeuDnrhiiNR0kN8c8mS0ih0rSj9xzUXTtsaSK8QrS) ![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Mallet by Wynwood House Casco Viejo Save 100% on your flight £1,375 per person 24 Dec - 29 Dec found 1 day ago Return flight included Port of Spain (POS) to Panama City (PTY) 9.8/10 Exceptional! (24 reviews) It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. Reviewed on 23 Jul 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=99778891&paandie=true&HotelClass=40&dealMarker=q5c9I7v4G9PbtUuIK1vwcDZTeuDnrhiiNR0kN8c8mS2Gk4d0K9l1B1BE5JchzE4f) ![Bristol Panama, a Registry Collection Hotel](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Bristol Panama, a Registry Collection Hotel Bella Vista £906 per person 24 Dec - 29 Dec found 1 day ago Return flight included Port of Spain (POS) to Panama City (PTY) 9.2/10 Wonderful! (1,008 reviews) Excelent atention to detail, recomended stay. Reviewed on 20 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=69638&paandie=true&HotelClass=40&dealMarker=yuypA8-xtriqmYgFhS2JQejrcnSr36sD_G7-usrfLPDpGmGCncq3bQShNsbWMBaX) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dreams Playa Bonita Panama - All Inclusive £1,493 per person 24 Dec - 29 Dec found 1 day ago Return flight included Port of Spain (POS) to Panama City (PTY) 7.4/10 Good! (1,006 reviews) Property and amenities were outdated with little effort to overcome those deficiencies through outstanding customer service. Options outside of costly renovations can and should be a part of the brand marketing and customer experience. Reviewed on 21 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=12445554&paandie=true&HotelClass=40&dealMarker=nK8J24UqA97-ssyMBUQjSNkTLwbYXBcfX_NZPTUsuwPdnf3OBMfWO4hytpGYV8ak) Don't see what you're looking for? See all available trips from Port of Spain to Panama Canal Zone [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2025-11-22/2025-11-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Adults Only holidays in Panama Canal Zone Price found within the past 48 hours. Click for updated prices. ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Waldorf Astoria Panama Bella Vista £901 per person 24 Dec - 29 Dec found 1 day ago Return flight included Port of Spain (POS) to Panama City (PTY) 9/10 Wonderful! (1,001 reviews) Absolutely fantastic experience. Beautiful property, wonderful staff, great food. Exceptional Reviewed on 17 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=4952056&paandie=true&HotelClass=50&dealMarker=yuypA8-xtriqmYgFhS2JQejrcnSr36sD_G7-usrfLPDJxgAYFEsRW-c_TnVxJIKf) ![Bristol Panama, a Registry Collection Hotel](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Bristol Panama, a Registry Collection Hotel Bella Vista £906 per person 24 Dec - 29 Dec found 1 day ago Return flight included Port of Spain (POS) to Panama City (PTY) 9.2/10 Wonderful! (1,008 reviews) Excelent atention to detail, recomended stay. Reviewed on 20 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=69638&paandie=true&HotelClass=50&dealMarker=yuypA8-xtriqmYgFhS2JQejrcnSr36sD_G7-usrfLPDpGmGCncq3bQShNsbWMBaX) ![The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz £1,052 per person 24 Dec - 29 Dec found 1 day ago Return flight included Port of Spain (POS) to Panama City (PTY) 9.6/10 Exceptional! (618 reviews) The staff were fantastic. The service was great. Reviewed on 13 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-24/2025-12-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=20958573&paandie=true&HotelClass=50&dealMarker=nK8J24UqA97-ssyMBUQjSAR2BkX11l6kOARv9kkZQkSPmycfOUVvWt9IuYqkLJZ3) Don't see what you're looking for? See all available trips from Port of Spain to Panama Canal Zone [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2025-11-22/2025-11-29/?FromAirport=POS&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## More holidays you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holiday packages](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## More Holiday Ideas [Flights to Panama Canal Zone](https://expedia.co.uk/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Hotels](https://expedia.co.uk/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Panama Canal Zone Holiday Rentals](https://expedia.co.uk/Panama-Canal-Zone-Holiday-Rentals.d6222968.Travel-Guide-HolidayRentals)[Panama Canal Zone Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-Canal-Zone.d6222968.Car-Hire-Guide)[Panama Canal Zone Holidays](https://expedia.co.uk/Panama-Canal-Zone.d6222968.Holidays-City-Breaks) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)