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£116 Cheap Flights from Knoxville (TYS) to Tampa (TPA)

View £116 flight on Tue, 6 Oct 2026Opens in a new window

Popular airlines from Alcoa - Knoxville Airport (TYS) to Tampa Intl. Airport (TPA)

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Cheap Flights from Knoxville (TYS) to Tampa (TPA)

Prices were available within the past 7 days and start at £116 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) cost?
You can find one-way and return flights from TYS to TPA with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when TYS to TPA ticket fares go up or down.
What is the cheapest month to fly from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
May is typically the cheapest month to fly from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.), with average return fares around £253. May often sees lower prices as it falls outside peak holiday seasons, making it a great time to find deals. Other cheap months to fly from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) include February and August.
Which airlines fly direct from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
Only one airline offers direct flights from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.). Southwest Airlines operates 7 direct flights from McGhee Tyson to Tampa Intl. every week.
What is the cheapest airline that flies from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
Frontier Airlines is one of the cheapest airlines offering connecting return flights, with tickets starting from around £133. Southwest Airlines is one of the cheapest airlines offering nonstop return flights from McGhee Tyson (TYS) to Tampa Intl. (TPA), with tickets starting from around £236 for flights that can be booked for departure within the next year. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
To find a cheap flight from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
The best airline to fly with from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) will differ from traveler to traveler. If you like to fly early, Southwest Airlines offers early morning flights. If price is the most important factor, Southwest Airlines typically offers the lowest fares. Delta offers the most daily flights from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
The best time to fly from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) is typically May or August. These months offer a great balance, with prices around £253 for a return flight. While these might be the cheapest months, you'll still find plenty of flight options to suit your schedule. This information is Helping you plan your trip with both good fares and excellent flight schedules in mind.
How many flights per day from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
There are approximately 49 connecting flights per day from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.). Some common connection points include Hartsfield-Jackson Atlanta Intl. (ATL), Charlotte-Douglas Intl. (CLT), and O'Hare Intl. (ORD).
What is the earliest flight from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
The earliest flight from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) typically departs around 5:00 AM local time. This service is operated by American Airlines and is seasonal, active in March and April. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
You'll typically find the most flights from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) on a Sunday, with around 30 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include American Airlines, Delta, and United. Sundays offer notably more flight options compared to other days of the week, so if flexibility allows, this could be a great day to fly.
What are the most popular departure times for flights from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
The most popular departure times for flights from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) are in the early morning, from 6am to 9am. Many major carriers, including American Airlines, Delta and Southwest Airlines, offer flights during this window. Many travellers prefer these times as it allows them to arrive at their destination early in the day, giving them more time to enjoy their trip.
How long does it take to fly from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
A non-stop flight from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) typically takes around 1 hour 48 minutes, covering a distance of about 880 kilometers. If you opt for a flight with one stop, your journey will usually be longer, taking around 5 hours 48 minutes. Flights with two or more stops will extend your travel time further, typically to about 9 hours 18 minutes. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your trip.
Can you fly business or first class from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
Yes, you can fly business class or first class between TYS and TPA. You can fly business class with Frontier Airlines and Delta.First class cabins are available on United, Delta, and American Airlines.
How do I earn miles on a Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) flight with Expedia?
It's easy to earn miles on a Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Tampa, FL (TPA) from Knoxville, TN (TYS)?
If you're planning to travel to Tampa from McGhee Tyson (TYS), you can fly directly into Tampa Intl. (TPA). Some flights may connect through major hubs like Nashville Intl. (BNA), Washington Dulles Intl. (IAD), or Baltimore Washington Intl. Thurgood Marshall (BWI) before reaching Tampa. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) at the last minute?
Typically, booking a last minute flight from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) flight and hotel package?
Securing a Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.)?
If you booked your Knoxville, TN (TYS-McGhee Tyson) to Tampa, FL (TPA-Tampa Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
McGhee Tyson
Destination airport
Tampa Intl.
Distance
875 km

Book with confidence

Compare flights from Knoxville to Tampa easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Knoxville to Tampa. Operating between them flights per day, 2 airlines cover the route. And fly direct, getting you to Tampa Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from McGhee Tyson to Tampa Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from McGhee Tyson (TYS) to Tampa Intl. (TPA)

The easiest way to view the best deals on flights from Knoxville to Tampa today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from McGhee Tyson to Tampa Intl. start at just and range up to .  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Knoxville and Tampa
  • booking your flight during , the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Knoxville to Tampa flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from McGhee Tyson to Tampa Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Knoxville to Tampa easily and book with confidence
*Available to Expedia members.