£159 Cheap Flights from Syracuse (SYR) to San Francisco (SFO)

View £159 flight on Fri, 29 May 2026Opens in a new window

Popular airlines from Hancock Intl. Airport (SYR) to San Francisco International Airport (SFO)

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Cheap Flights from Syracuse (SYR) to San Francisco (SFO)

Prices were available within the past 7 days and start at £159 for one-way flights and £288 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, 29 May - Tue, 2 Jun
SYR
Syracuse
SFO
San Francisco
£288 Return, found 4 days ago
£288
Return
found 4 days ago
Select Delta flight, departing Fri, 29 May from Syracuse to San Francisco, returning Tue, 2 Jun, priced at £288 found 4 days ago
Delta
Fri, 29 May - Mon, 8 Jun
SYR
Syracuse
SFO
San Francisco
£302 Return, found 4 days ago
£302
Return
found 4 days ago
Select Delta flight, departing Fri, 29 May from Syracuse to San Francisco, returning Mon, 8 Jun, priced at £302 found 4 days ago
Delta
Mon, 1 Jun - Tue, 2 Jun
SYR
Syracuse
SFO
San Francisco
£317 Return, found 4 days ago
£317
Return
found 4 days ago
Select Delta flight, departing Mon, 1 Jun from Syracuse to San Francisco, returning Tue, 2 Jun, priced at £317 found 4 days ago
JetBlue Airways
Fri, 29 May - Sat, 6 Jun
SYR
Syracuse
SFO
San Francisco
£323 Return, found 4 days ago
£323
Return
found 4 days ago
Select JetBlue Airways flight, departing Fri, 29 May from Syracuse to San Francisco, returning Sat, 6 Jun, priced at £323 found 4 days ago
Delta
Wed, 27 May - Sat, 6 Jun
SYR
Syracuse
SFO
San Francisco
£328 Return, found 4 days ago
£328
Return
found 4 days ago
Select Delta flight, departing Wed, 27 May from Syracuse to San Francisco, returning Sat, 6 Jun, priced at £328 found 4 days ago
American Airlines
Fri, 29 May - Sun, 31 May
SYR
Syracuse
SFO
San Francisco
£329 Return, found 4 days ago
£329
Return
found 4 days ago
Select American Airlines flight, departing Fri, 29 May from Syracuse to San Francisco, returning Sun, 31 May, priced at £329 found 4 days ago
American Airlines
Fri, 29 May - Sun, 31 May
SYR
Syracuse
SFO
San Francisco
£344 Return, found 4 days ago
£344
Return
found 4 days ago
Select American Airlines flight, departing Fri, 29 May from Syracuse to San Francisco, returning Sun, 31 May, priced at £344 found 4 days ago
JetBlue Airways
Tue, 26 May - Sat, 6 Jun
SYR
Syracuse
SFO
San Francisco
£346 Return, found 4 days ago
£346
Return
found 4 days ago
Select JetBlue Airways flight, departing Tue, 26 May from Syracuse to San Francisco, returning Sat, 6 Jun, priced at £346 found 4 days ago
United
Tue, 26 May - Mon, 8 Jun
SYR
Syracuse
SFO
San Francisco
£369 Return, found 4 days ago
£369
Return
found 4 days ago
Select United flight, departing Tue, 26 May from Syracuse to San Francisco, returning Mon, 8 Jun, priced at £369 found 4 days ago
Alaska Airlines
Fri, 29 May - Sun, 31 May
SYR
Syracuse
SFO
San Francisco
£388 Return, found 4 days ago
£388
Return
found 4 days ago
Select Alaska Airlines flight, departing Fri, 29 May from Syracuse to San Francisco, returning Sun, 31 May, priced at £388 found 4 days ago

Frequently asked questions

What is the cheapest month to fly from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
January is typically the cheapest month to fly from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.), with average return fares of approximately £263. This is about 23% lower than the average price throughout the past year. January often sees lower prices because it falls after the busy holiday travel season, when demand for flights tends to decrease. Other cheap months to fly from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) include September and October.
How do I find cheap flights from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
To find a cheap flight from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The best time to fly from Syracuse, NY (SYR-Hancock Intl.) (SYR) to San Francisco, CA (SFO-San Francisco Intl.) (SFO) for a good value is typically January or September. Based on booking data from the past year, you can expect average return flight prices around £263 during these months. While we don't have specific popularity data for this route, these months often offer a balance of lower prices and reasonable flight availability, allowing you to plan your trip without breaking the bank.
How many flights per day from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
There are approximately 45 connecting flights per day from Syracuse, NY (SYR-Hancock Intl.) (SYR) to San Francisco, CA (SFO-San Francisco Intl.) (SFO). Some common connection points include O'Hare Intl. (ORD), Washington Dulles Intl. (IAD), and Detroit Metropolitan Wayne County (DTW).
What is the earliest flight from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The earliest flight from Syracuse, NY (SYR-Hancock Intl.) (SYR) to San Francisco, CA (SFO-San Francisco Intl.) (SFO) typically departs at approximately 5:00 AM local time. This is a seasonal service active in November, operated by American Airlines. An early departure like this can help you maximise your time in San Francisco. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
If you're flying from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.), you'll typically find the most flights on a Monday, with around 33 flights available. This gives you a good selection of options to choose from. Major airlines on this route include United Airlines, American Airlines, and Delta Air Lines. Flight schedules are consistent throughout the week, so you'll have plenty of options regardless of your travel day.
What are the most popular departure times for flights from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The most popular departure times for flights from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) are in the morning, between 6am and 9am. About 37% of passengers prefer this time. Many major carriers, including United Airlines, American Airlines and Delta Air Lines, offer flights during this window. This timing works well because you can get an early start to your travel day and arrive in San Francisco with plenty of time to settle in.
How long does it take to fly from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
Flying from SYR to SFO with a connection usually takes about 10 hours, traveling roughly 2,434 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
Select the "Business class" and "First class" filters when looking for SYR to SFO flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight with Expedia?
It's easy to earn miles on a Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Francisco from Hancock Intl. (SYR)?
From Hancock Intl. (SYR), you can fly directly into San Francisco Intl. (SFO) to reach San Francisco. Some flights may connect through major hubs like O'Hare Intl. (ORD), Ronald Reagan Washington National (DCA), Denver Intl. (DEN) before reaching San Francisco. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) at the last minute?
Typically, booking a last minute flight from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package?
Securing a Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
If you booked your Syracuse, NY (SYR-Hancock Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Hancock Intl.
Destination airport
San Francisco Intl.
Return price
£288
Distance
3894 km

Book with confidence

Compare flights from Syracuse to San Francisco easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Syracuse to San Francisco. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Hancock Intl. to San Francisco Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Hancock Intl. (SYR) to San Francisco Intl. (SFO)

The easiest way to view the best deals on flights from Syracuse to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Hancock Intl. to San Francisco Intl. start at just £288 and range up to £388.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Syracuse and San Francisco
  • booking your flight during May, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Syracuse to San Francisco flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Hancock Intl. to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Syracuse to San Francisco easily and book with confidence

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*Available to Expedia members.