Title: £463 Cheap Flights from Santiago to Lyon (SCL to LYS) - Expedia.co.uk ![](https://images.trvl-media.com/place/6180797/83e09277-fd3a-4f49-b5bf-b664a870ce2f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6180797/83e09277-fd3a-4f49-b5bf-b664a870ce2f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £463 Cheap Flights from Santiago (SCL) to Lyon (LYS) [View £463 flight on Sat, 21 Feb 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:SCL,to:LYS,departure:21/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:462.40&airProductToken=AQqSAQouCMyCARIDNjA3GNJYIKakASiI5oUDMPPnhQM4TkAAWAFqAlNMcghOTEVTTFo2QgovCMyCARIEODA3NhimpAEgjBgoj_GFAzDs9YUDOE5AAVgBagJTTHIITkxFU0xaNkIKLwjMggESBDE4MzkYjBggi5YBKLb4hQMwpPmFAzhOQAFYAWoCU0xyCE5MRVNMWjZCEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Santiago Intl. Airport (SCL) to Saint-Exupery Airport (LYS) - ![British Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_BA.svg) British Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:lys,departure:02/10/2025TANYT&leg2=from:lys,to:scl,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"BA"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:lys,departure:02/10/2025TANYT&leg2=from:lys,to:scl,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:lys,departure:02/10/2025TANYT&leg2=from:lys,to:scl,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:lys,departure:02/10/2025TANYT&leg2=from:lys,to:scl,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:lys,departure:02/10/2025TANYT&leg2=from:lys,to:scl,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:lys,departure:02/10/2025TANYT&leg2=from:lys,to:scl,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![Iberia](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_IB.svg) Iberia [](https://www.expedia.co.uk/Flights-Search?leg1=from:scl,to:lys,departure:02/10/2025TANYT&leg2=from:lys,to:scl,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"IB"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Santiago (SCL) to Lyon (LYS) Prices were available within the past 7 days and start at £463 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ## Travel information | Origin airport | Arturo Merino Benitez | | --- | --- | | Destination airport | Saint-Exupery | | Distance | 11560 km | ## Book with confidence ### Compare flights from Santiago to Lyon easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Santiago to Lyon. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Saint-Exupery in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Arturo Merino Benitez to Saint-Exupery.   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Arturo Merino Benitez (SCL) to Saint-Exupery (LYS) The easiest way to view the best deals on flights from Santiago to Lyon today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Arturo Merino Benitez to Saint-Exupery start at just and range up to .   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Santiago and Lyon - booking your flight during , the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Santiago to Lyon flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Arturo Merino Benitez to Saint-Exupery for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. 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