---
title: "£461 Cheap Flights from Panama City to Johannesburg (PTY to JNB) - Expedia.co.uk"
description: "Reserve one-way or return flights from Panama City to Johannesburg with no change fee on selected flights. Earn your airline miles on top of our rewards! Get 2026 flight deals for now!"
canonical: "https://www.expedia.co.uk/lp/flights/pty/jnb/panama-city-to-johannesburg"
language: en-GB
market: GB
currency: GBP
prices_as_of: 2026-11-13T19:15:24Z
---

# £461 Cheap Flights from Panama City (PTY) to Johannesburg (JNB)
![A road with two large water towers and trees in the background.](https://images.trvl-media.com/place/4345418/5c037d86-90c0-47c3-8dc5-ba2d1b8b8306.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

[View £461 flight on Mon, 30 Nov 2026](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:30/11/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:460.80&airProductToken=AQptCjUIy5gBEgM3NTgY78QBIICTASiRyp4DMILPngM4R0AAWAFqCExJR0hUQkFHcghHUkwwQkhSQQo0CMuYARIDNTkxGICTASCpCyjm2Z4DMPDengM4R0ABWAFqCExJR0hUQkFHcghHUkwwQkhSQRIKCAEQARgBKgJLTBgBIgQIARABKAIoAygEMAE6JGY5MWIwZTIyLTMzNjktNGI4Zi04ZWZhLTdmOWE1YjgzY2E5YQ)

## Popular airlines from Tocumen Intl. Airport (PTY) to O.R. Tambo Intl. Airport (JNB)

[Turkish Airlines](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:27/11/2026TANYT&leg2=from:JNB,to:PTY,departure:04/12/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TK"}}])

[Lufthansa](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:27/11/2026TANYT&leg2=from:JNB,to:PTY,departure:04/12/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LH"}}])

[Air France](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:27/11/2026TANYT&leg2=from:JNB,to:PTY,departure:04/12/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}])

[KLM](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:27/11/2026TANYT&leg2=from:JNB,to:PTY,departure:04/12/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}])

[United](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:27/11/2026TANYT&leg2=from:JNB,to:PTY,departure:04/12/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}])

[Delta](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:27/11/2026TANYT&leg2=from:JNB,to:PTY,departure:04/12/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}])

[Qatar Airways](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:27/11/2026TANYT&leg2=from:JNB,to:PTY,departure:04/12/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"QR"}}])

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## Cheap Flights from Panama City to Johannesburg (PTY-JNB)

Prices were available within the past 7 days and start at £461 for one-way flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

One way

[Select KLM flight, departing Mon, 30 Nov from Panama City to Johannesburg, priced at £461 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:30/11/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:460.80&airProductToken=AQptCjUIy5gBEgM3NTgY78QBIICTASiRyp4DMILPngM4R0AAWAFqCExJR0hUQkFHcghHUkwwQkhSQQo0CMuYARIDNTkxGICTASCpCyjm2Z4DMPDengM4R0ABWAFqCExJR0hUQkFHcghHUkwwQkhSQRIKCAEQARgBKgJLTBgBIgQIARABKAIoAygEMAE6JGY5MWIwZTIyLTMzNjktNGI4Zi04ZWZhLTdmOWE1YjgzY2E5YQ)

PTY · JNB · From £461 · One way

[Select KLM flight, departing Mon, 30 Nov from Panama City to Johannesburg, priced at £520 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:30/11/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:519.60&airProductToken=AQpvCjYIy5gBEgM3NTgY78QBIICTASiRyp4DMILPngM4R0AAWAFqCVNUQU5EQVJEM3IIR1JMMEJISkEKNQjLmAESAzU5MRiAkwEgqQso5tmeAzDw3p4DOEdAAVgBaglTVEFOREFSRDNyCEdSTDBCSEpBEgoIARABGAEqAktMGAEiBAgBEAEoAigDKAQwATokZjkxYjBlMjItMzM2OS00YjhmLThlZmEtN2Y5YTViODNjYTlh)

PTY · JNB · From £520 · One way

[Select United flight, departing Fri, 29 Jan from Panama City to Johannesburg, priced at £527 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:29/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:526.10&airProductToken=AQqtAQpACNWCARIENzE3MRjvxAEgrhwolOijAzDm6qMDOFZAAFgBagdFQ09OT01ZcghWTkQ3MFBOQ3oKCMOaARIENzE3MQo0CNWCARIEMTY3NxiuHCDEjQEoxuyjAzDS7aMDOFZAAVgBagdFQ09OT01ZcghWTkQ3MFBOQwozCNWCARIDMTg4GMSNASCpCyiO7qMDMIP1owM4VkABWAFqB0VDT05PTVlyCFZORDcwUE5DEgoIARABGAEqAlVBGAEiBAgBEAEoAigDKAQwATokY2U0YzYwMDYtODhjNS00NDliLTk4ZDgtMzgxYjhhYjUzMWMz)

PTY · JNB · From £527 · One way

[Select Air Europa flight, departing Sun, 29 Nov from Panama City to Johannesburg, priced at £669 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:29/11/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:668.40&airProductToken=AQpeCi0I1bABEgI1NhjvxAEgjBgolsCeAzDVxJ4DOFpAAFgBagRMSVRFcgZaWVlPMkwKLQjVsAESAzE1NxiMGCCpCyjLyZ4DMKjOngM4WkABWAFqBExJVEVyBlpZWU8yTBIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE6JDg3ZTUxNmY2LWU1YzctNDZkZS05YzhhLTA4NDk0YzUwZDZlMA)

PTY · JNB · From £669 · One way

[Select Air Europa flight, departing Thu, 28 Jan from Panama City to Johannesburg, priced at £791 Found 6 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:28/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:790.40&airProductToken=AQpeCi0I1bABEgI1NhjvxAEgjBgoluOjAzDV56MDOFRAAFgBagRMSVRFcgZUTFlPN0wKLQjVsAESAzE1NxiMGCCpCyjL7KMDMKjxowM4VEABWAFqBExJVEVyBlRMWU83TBIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE6JDM2MjhmNTg4LTJiYTUtNDNlMC1hMGYwLTQ0MmY5YjVkNWQyMA)

PTY · JNB · From £791 · One way

[Select Air Europa flight, departing Thu, 28 Jan from Panama City to Johannesburg, priced at £830 Found 6 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:28/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:829.90&airProductToken=AQpmCjEI1bABEgI1NhjvxAEgjBgoluOjAzDV56MDOFRAAFgBaghTVEFOREFSRHIGVExZTzdTCjEI1bABEgMxNTcYjBggqQsoy-yjAzCo8aMDOFRAAVgBaghTVEFOREFSRHIGVExZTzdTEgoIARABGAEqAlVYGAEiBAgBEAEoAigDKAQwATokMzYyOGY1ODgtMmJhNS00M2UwLWEwZjAtNDQyZjliNWQ1ZDIw)

PTY · JNB · From £830 · One way

[Select Air Europa flight, departing Thu, 28 Jan from Panama City to Johannesburg, priced at £894 Found 6 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:28/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:893.10&airProductToken=AQpeCi0I1bABEgI1NhjvxAEgjBgoluOjAzDV56MDOFRAAFgBagRGTEVYcgZUTFlPN0gKLQjVsAESAzE1NxiMGCCpCyjL7KMDMKjxowM4VEABWAFqBEZMRVhyBlRMWU83SBIKCAEQARgBKgJVWBgBIgQIARABKAIoAygEMAE6JDM2MjhmNTg4LTJiYTUtNDNlMC1hMGYwLTQ0MmY5YjVkNWQyMA)

PTY · JNB · From £894 · One way

[Select Copa flight, departing Thu, 28 Jan from Panama City to Johannesburg, priced at £1,033 Found 6 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:28/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1032.50&airProductToken=AQqBAQoqCMOaARIDNzAxGO%5FEASCmpAEo1t6jAzD24aMDOFdAAFgBcgdISFhPV0JSCikIxagBEgM1MDcYpqQBIOAYKI7kowMw3umjAzhIQAFYAXIHSEhYT1dCUgooCMWoARIDODU5GOAYIKkLKM7rowMwk-6jAzhIQAFYAXIHSEhYT1dCUhIKCAEQARgBKgJFVBgBIgQIARABKAIoAygEMAE6JDM2MjhmNTg4LTJiYTUtNDNlMC1hMGYwLTQ0MmY5YjVkNWQyMA)

PTY · JNB · From £1,033 · One way

[Select Turkish Airlines flight, departing Thu, 28 Jan from Panama City to Johannesburg, priced at £1,038 Found 6 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:28/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1037.70&airProductToken=AQpaCiwI1JYBEgM4MDEY78QBIMicASj24aMDMPPnowM4VEAAWAFqAkNMcgVUVkNMTwoqCNSWARICMzgYyJwBIKkLKOnsowMwvPGjAzhUQAFYAWoCQ0xyBVRWQ0xPEgoIARABGAEqAlRLGAEiBAgBEAEoAigDKAQwATokMzYyOGY1ODgtMmJhNS00M2UwLWEwZjAtNDQyZjliNWQ1ZDIw)

PTY · JNB · From £1,038 · One way

[Select Copa flight, departing Mon, 15 Feb from Panama City to Johannesburg, priced at £1,039 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:15/02/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1038.90&airProductToken=AQqBAQoqCMOaARIDNzAxGO%5FEASCmpAEolqmlAzC2rKUDOFdAAFgBcgdISFhPV0JSCikIxagBEgM1MDcYpqQBIOAYKM6upQMwnrSlAzhIQAFYAXIHSEhYT1dCUgooCMWoARIDODU5GOAYIKkLKI62pQMw07ilAzhIQAFYAXIHSEhYT1dCUhIKCAEQARgBKgJFVBgBIgQIARABKAIoAygEMAE6JGVjM2Q5M2QzLTlhMTAtNDM3NS1hYWQ2LTZhYjhhZjQ3MjBiNw)

PTY · JNB · From £1,039 · One way

[Select Copa flight, departing Mon, 25 Jan from Panama City to Johannesburg, priced at £1,043 Found 3 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:25/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1042.40&airProductToken=AQqBAQoqCMOaARIDNzAxGO%5FEASCmpAEo9ryjAzCWwKMDOE9AAFgBcgdISFhPV0JSCikIxagBEgM1MDcYpqQBIOAYKK7CowMw%5FsejAzhIQAFYAXIHSEhYT1dCUgooCMWoARIDODU5GOAYIKkLKO7JowMws8yjAzhIQAFYAXIHSEhYT1dCUhIKCAEQARgBKgJFVBgBIgQIARABKAIoAygEMAE6JDA4ODgxOWM2LTY3YWYtNDIyOS04YjlkLWIzOGQ5Y2Y0NWMzMA)

PTY · JNB · From £1,043 · One way

[Select Turkish Airlines flight, departing Fri, 29 Jan from Panama City to Johannesburg, priced at £1,043 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:29/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1042.90&airProductToken=AQpbCiwI1JYBEgM5MDQY78QBIMicASjU7qMDMNH0owM4VEAAWAFqAkNMcgVUVkNMTworCNSWARIDMjQyGMicASCpCyi2%5FaMDMImCpAM4VEABWAFqAkNMcgVUVkNMTxIKCAEQARgBKgJUSxgBIgQIARABKAIoAygEMAE6JGNlNGM2MDA2LTg4YzUtNDQ5Yi05OGQ4LTM4MWI4YWI1MzFjMw)

PTY · JNB · From £1,043 · One way

[Select Turkish Airlines flight, departing Mon, 25 Jan from Panama City to Johannesburg, priced at £1,048 Found 3 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:25/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1047.50&airProductToken=AQpbCiwI1JYBEgM5MDQY78QBIMicASjUwaMDMNHHowM4VEAAWAFqAkNMcgVUVkNMTworCNSWARIDMjQyGMicASCpCyi20KMDMInVowM4VEABWAFqAkNMcgVUVkNMTxIKCAEQARgBKgJUSxgBIgQIARABKAIoAygEMAE6JDA4ODgxOWM2LTY3YWYtNDIyOS04YjlkLWIzOGQ5Y2Y0NWMzMA)

PTY · JNB · From £1,048 · One way

[Select Turkish Airlines flight, departing Thu, 28 Jan from Panama City to Johannesburg, priced at £1,070 Found 6 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:28/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1069.80&airProductToken=AQpaCiwI1JYBEgM4MDEY78QBIMicASj24aMDMPPnowM4VEAAWAFqAkxHcgVUVkxHTwoqCNSWARICMzgYyJwBIKkLKOnsowMwvPGjAzhUQAFYAWoCTEdyBVRWTEdPEgoIARABGAEqAlRLGAEiBAgBEAEoAigDKAQwATokMzYyOGY1ODgtMmJhNS00M2UwLWEwZjAtNDQyZjliNWQ1ZDIw)

PTY · JNB · From £1,070 · One way

[Select Copa flight, departing Thu, 28 Jan from Panama City to Johannesburg, priced at £1,072 Found 6 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:28/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1071.30&airProductToken=AQqaAQoyCMOaARIDNDE1GO%5FEASDBMyjT3qMDMLXfowM4RUAAWAFqCFNUQU5EQVJEcgZSTFlPN1MKMQjVsAESAzE5NBjBMyCMGCib46MDMNrnowM4UkABWAFqCFNUQU5EQVJEcgZSTFlPN1MKMQjVsAESAzE1NxiMGCCpCyjL7KMDMKjxowM4UkABWAFqCFNUQU5EQVJEcgZSTFlPN1MSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDABOiQzNjI4ZjU4OC0yYmE1LTQzZTAtYTBmMC00NDJmOWI1ZDVkMjA)

PTY · JNB · From £1,072 · One way

[Select Turkish Airlines flight, departing Fri, 30 Apr from Panama City to Johannesburg, priced at £1,075 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:30/04/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1075.00&airProductToken=AQpbCiwI1JYBEgM4MDAY78QBIMicASjL7asDMM3zqwM4VEAAWAFqAkxHcgVUVkxHTworCNSWARIDMjQyGMicASCpCyi0%5FasDMPiBrAM4VEABWAFqAkxHcgVUVkxHTxIKCAEQARgBKgJUSxgBIgQIARABKAIoAygEMAE6JDlmMDQzZWQ1LWNiZDQtNGVhMy05NjM0LWFjODRmYjY3ZDBlOA)

PTY · JNB · From £1,075 · One way

[Select Air France flight, departing Wed, 10 Feb from Panama City to Johannesburg, priced at £1,262 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:10/02/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1261.30&airProductToken=AQprCjQIwYwBEgM0NzUY78QBIOIwKPL1pAMwyvqkAzhUQABYAWoITElHSFRCQUdyCFRSU0ZCQlJBCjMIwYwBEgM5OTAY4jAgqQso4f6kAzD1g6UDOFRAAVgBaghMSUdIVEJBR3IIVFJTRkJCUkESCggBEAEYASoCQUYYASIECAEQASgCKAMoBDABOiRiYTk1MjgzOS1kNGNmLTQ1ZTMtODE5Yy1jOTM3YWUwNTkwYzg)

PTY · JNB · From £1,262 · One way

[Select Iberia flight, departing Wed, 10 Feb from Panama City to Johannesburg, priced at £1,305 Found 1 day ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:10/02/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1304.40&airProductToken=AQq3AQozCMmEARIDMjU4GO%5FEASCMGCiH9KQDMOT4pAM4VkAAWAFqB0NPTUZPUlRyCFZETDBOT1UzCj8IyYQBEgQ2MjI2GIwYIMM7KPz6pAMw%5Ff2kAzhWQAFYAWoHQ09NRk9SVHIIVkRMME5PVTN6CgjRpAESBDYyMjYKPwjJhAESBDYxNTUYwzsgqQso1%5F6kAzDQgqUDOFZAAVgBagdDT01GT1JUcghWREwwTk9VM3oKCNGkARIENjE1NRIKCAEQARgBKgJJQhgBIgQIARABKAIoAygEMAE6JGJhOTUyODM5LWQ0Y2YtNDVlMy04MTljLWM5MzdhZTA1OTBjOA)

PTY · JNB · From £1,305 · One way

[Select Qatar Airways flight, departing Thu, 28 Jan from Panama City to Johannesburg, priced at £1,356 Found 6 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:28/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:1355.70&airProductToken=AQq0AQpDCNGkARIEMjQ5MBjvxAEgjAIo7t-jAzCq4aMDOFZAAFgBagpFQ09OVkVOSUVOcghWTFI1UjFTSXoKCMGCARIEMjQ5MAo1CNGkARIDNzc4GIwCIMM7KI%5FiowMwvuijAzhWQAFYAWoKRUNPTlZFTklFTnIIVkxSNVIxU0kKNgjRpAESBDEzNjMYwzsgqQsosuyjAzCw8KMDOFZAAVgBagpFQ09OVkVOSUVOcghWTFI1UjFTSRIKCAEQARgBKgJRUhgBIgQIARABKAIoAygEMAE6JDM2MjhmNTg4LTJiYTUtNDNlMC1hMGYwLTQ0MmY5YjVkNWQyMA)

PTY · JNB · From £1,356 · One way

[Select Lufthansa flight, departing Fri, 8 Jan from Panama City to Johannesburg, priced at £4,302 Found 3 days ago](https://www.expedia.co.uk/Flights-Search?leg1=from:PTY,to:JNB,departure:08/01/2027TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:4301.90&airProductToken=AQqYAQo6CMyQARIENTQ4MRjvxAEgwTMo3YCiAzDIgaIDOFlAAFgBagdFQ09GTEVYcgJZMXoKCMOaARIENTQ4MQosCMyQARIDNTQzGMEzIKUEKP-CogMw%5F4eiAzhZQAFYAWoHRUNPRkxFWHICWTEKLAjMkAESAzU3MhilBCCpCyjsiqIDMOyPogM4WUABWAFqB0VDT0ZMRVhyAlkxEgoIARABGAEqAkxIGAEiBAgBEAEoAigDKAQwATokODI3MzUwZGItNjU1NC00Y2VkLTk2NTgtNWE3NjBiNjgzYjI1)

PTY · JNB · From £4,302 · One way

## Book with confidence

### Compare flights from Panama City to Johannesburg easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Panama City to Johannesburg. Operating between them flights per day, 9 airlines cover the route. And fly direct, getting you to O.R. Tambo Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tocumen Intl. to O.R. Tambo Intl..

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.

#### Grab a great deal on your flight from Tocumen Intl. (PTY) to O.R. Tambo Intl. (JNB)

The easiest way to view the best deals on flights from Panama City to Johannesburg today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tocumen Intl. to O.R. Tambo Intl. start at just and range up to .

To find an even better deal, try

- being flexible on your dates – midweek flights can be cheaper
- looking for other airports near Panama City and Johannesburg
- booking your flight during , the cheapest month on this route
- varying your flight times – early morning and late at night are sometimes cheaper

#### Why you should book your Panama City to Johannesburg flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tocumen Intl. to O.R. Tambo Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.

## Frequently Asked Questions

### How much does a flight from Panama City (PTY) to Johannesburg (JNB) cost?

You can find one-way and return flights from Panama City (PTY) to Johannesburg (JNB) with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when PTY to JNB ticket fares go up or down.

### What is the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

The cheapest months to fly from PTY to JNB are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.

### Which airlines fly direct from Panama City (PTY) to Johannesburg (JNB)?

Enter PTY to JNB and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

### What is the cheapest airline that flies from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

Avianca is one of the cheapest airlines offering connecting return flights from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.), with tickets starting from around £1913 for flights that can be booked for departure within the next year. These flights typically include a layover in El Dorado Intl. (BOG). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.

### How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up [Price Tracking](https://www.expedia.co.uk/why/price-tracking) and receive alerts when fares go up or down.

### What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.

### How many flights per day from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

There are around 16 connecting flights per day from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.). Some common connection points include Adolfo Suarez Madrid-Barajas (MAD), Schiphol (AMS), and George Bush Intercontinental (IAH).

### What is the earliest flight from Panama City (PTY) to Johannesburg (JNB)?

Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from Panama City (PTY) to Johannesburg (JNB). To compare more early flights, use the "Early Morning" and "Morning" filters in your search.

### What day of the week has the most flights from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

You'll generally find the most flights from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) on a Monday, with around 32 flights available. This gives you a good selection of options for your journey. Major airlines on this route include Copa, American Airlines, and United. Flight schedules are fairly consistent throughout the week, with only a slight variation in the number of flights on other days.

### What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) are between 9am and 12pm. Many major carriers, including United and Copa, offer flights during this window. Many travellers prefer this time as it allows for a morning departure, giving you a full day to settle in at your destination.

### How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

A flight from PTY to JNB with a layover takes around 22 hours 20 minutes, with the route covering approximately 12,204 kilometers. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

### Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

Yes, you can fly business class between PTY and JNB. Airlines that offer business class service on this route include:

\* Turkish Airlines
\* KLM
\* Air France
\* Air Europa
\* Delta
\* American Airlines

### How do I earn miles on a Panama City (PTY) to Johannesburg (JNB) flight with Expedia?

It's easy to earn miles on a Panama City (PTY) to Johannesburg (JNB) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of [One Key™](https://www.expedia.co.uk/welcome-one-key), you can also earn OneKeyCash™\* on top of your airline miles when you book with Expedia.

\*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

### Is it cheaper to buy a plane ticket from Panama City (PTY) to Johannesburg (JNB) at the last minute?

Typically, booking a last minute flight from Panama City (PTY) to Johannesburg (JNB) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

### Is it cheaper to book a Panama City (PTY) to Johannesburg (JNB) flight and hotel package?

Securing a Panama City (PTY) to Johannesburg (JNB) [flight and hotel package](https://www.expedia.co.uk/johannesburg.d6051471.holidays-city-breaks) is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

### Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.)?

If you booked your Panama City (PTY-Tocumen Intl.) to Johannesburg (JNB-O.R. Tambo Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in [your itinerary](https://www.expedia.co.uk/trips) or confirmation email. Or, head to our [Customer Service portal](https://www.expedia.co.uk/helpcenter/) if you'd like more information.

## Travel information

| Origin airport      | Tocumen Intl. Airport                                                                                             |
| ------------------- | ----------------------------------------------------------------------------------------------------------------- |
| Destination airport | O.R. Tambo Intl. Airport                                                                                          |
| Distance            | 7,581 miles away                                                                                                  |
| Airlines serving    | Turkish Airlines, Lufthansa, Air France, KLM, United, Delta, Qatar Airways, Air Europa, American Airlines, Iberia |
| Popular airline     | Turkish Airlines                                                                                                  |
| Return price        | £461                                                                                                              |

## Explore a world of travel with Expedia

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\*Available to Expedia members.

## Other language versions

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  en-US: https://www.expedia.com/lp/flights/pty/jnb/panama-city-to-johannesburg
  ar: https://www.expedia.sa/lp/flights/pty/jnb/panama-city-to-johannesburg
  es: https://www.expedia.com/es/lp/vuelos/pty/jnb/panama-a-johannesburgo
  en-CA: https://www.expedia.ca/lp/flights/pty/jnb/panama-city-to-johannesburg
```