Title: £513 Cheap Flights from Yaounde to Johannesburg (NSI to JNB) - Expedia.co.uk ![](https://images.trvl-media.com/place/6051471/f8638339-de97-4674-86e9-4e3632bbc2b3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6051471/f8638339-de97-4674-86e9-4e3632bbc2b3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £513 Cheap Flights from Yaounde (NSI) to Johannesburg (JNB) [View £513 flight on Sun, 21 Sept 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:513.00&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Yaounde (NSI-Nsimalen Intl.) to O.R. Tambo Intl. Airport (JNB) - ![Ethiopian Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_ET.svg) Ethiopian Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:nsi,to:jnb,departure:02/10/2025TANYT&leg2=from:jnb,to:nsi,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"ET"}}]) - ![Turkish Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TK.svg) Turkish Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:nsi,to:jnb,departure:02/10/2025TANYT&leg2=from:jnb,to:nsi,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TK"}}]) - ![ASKY](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KP.svg) ASKY [](https://www.expedia.co.uk/Flights-Search?leg1=from:nsi,to:jnb,departure:02/10/2025TANYT&leg2=from:jnb,to:nsi,departure:09/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KP"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Yaounde (NSI) to Johannesburg (JNB) Prices were available within the past 7 days and start at £513 for one-way flights and £884 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Ethiopian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/ET.gif) Sat, 13 Dec - Sat, 3 Jan NSI Yaoundé JNB Johannesburg £884 Return found 1 hour ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:13/12/2025TANYT&leg2=from:JNB,to:NSI,departure:03/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:883.06&airProductToken=AQpQCiYIxagBEgM5NTUYzUQg4Bgonsz_AjCzz_8COExAAFgBcgVMRVNDTQomCMWoARIDODU5GOAYIKkLKM7Q_wIwk9P_AjhMQAFYAXIFTEVTQ00KUAomCMWoARIDODU4GKkLIOAYKIy9gQMw27-BAzhMQABYAXIFTEVTQ00KJgjFqAESAzkyNRjgGCDNRCitwYEDMMLEgQM4TEABWAFyBUxFU0NNEgoIARABGAEqAkVUGAEiBAgBEAEoAigEKAYwAQ) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Fri, 26 Sept NSI Yaoundé JNB Johannesburg £885 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:26/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:884.90&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![Ethiopian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/ET.gif) Sun, 21 Sept - Fri, 26 Sept NSI Yaoundé JNB Johannesburg £928 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:26/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:927.30&airProductToken=AQpQCiYIxagBEgM5MjUYzUQg4Bgo3qf4AjDTqfgCOEtAAFgBcgVLRUVDTQomCMWoARIDODU5GOAYIKkLKO6q-AIws634AjhLQAFYAXIFS0VFQ00KUAomCMWoARIDODU4GKkLIOAYKKLj-AIw8eX4AjhLQABYAXIFS0VFQ00KJgjFqAESAzk1NRjgGCDNRCjN5_gCMMLp-AI4S0ABWAFyBUtFRUNNEgoIARABGAEqAkVUGAEiBAgBEAEoAigEKAYwAQ) ![Ethiopian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/ET.gif) Tue, 30 Sept - Wed, 1 Oct NSI Yaoundé JNB Johannesburg £975 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:30/09/2025TANYT&leg2=from:JNB,to:NSI,departure:01/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:974.04&airProductToken=AQpQCiYIxagBEgM5NTUYzUQg4Bgo3ov5AjDzjvkCOExAAFgBcgVMRVNDTQomCMWoARIDODU5GOAYIKkLKI6Q-QIw05L5AjhMQAFYAXIFTEVTQ00KUAomCMWoARIDODU4GKkLIOAYKMKb-QIwkZ75AjhNQABYAXIFTUVFQ00KJgjFqAESAzk1NRjgGCDNRCjtn_kCMOKh-QI4TUABWAFyBU1FRUNNEgoIARABGAEqAkVUGAEiBAgBEAEoAigEKAYwAQ) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,031 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1030.90&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,074 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1074.00&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Fri, 26 Sept NSI Yaoundé JNB Johannesburg £1,097 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:26/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1097.00&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,143 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1143.00&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,150 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1150.00&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Fri, 26 Sept NSI Yaoundé JNB Johannesburg £1,170 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:26/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1170.00&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,245 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1244.60&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![Ethiopian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/ET.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,260 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1259.30&airProductToken=AQpQCiYIxagBEgM5MjUYzUQg4Bgo3qf4AjDTqfgCOFNAAFgBcgVTUlRDTQomCMWoARIDODU5GOAYIKkLKO6q-AIws634AjhTQAFYAXIFU1JUQ00KUAomCMWoARIDODU4GKkLIOAYKMLu-AIwkfH4AjhTQABYAXIFU1JUQ00KJgjFqAESAzkyNRjgGCDNRCjt8vgCMIL2-AI4U0ABWAFyBVNSVENNEgoIARABGAEqAkVUGAEiBAgBEAEoAigEKAYwAQ) ![Ethiopian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/ET.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,269 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1268.30&airProductToken=AQpQCiYIxagBEgM5MjUYzUQg4Bgo3qf4AjDTqfgCOEtAAFgBcgVLT1dDTQomCMWoARIDODU5GOAYIKkLKO6q-AIws634AjhLQAFYAXIFS09XQ00SCggBEAEYASoCRVQYASIECAEQASgCKAQoBjAB) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,271 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1271.00&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,289 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1288.70&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![Ethiopian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/ET.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,363 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1362.90&airProductToken=AQpQCiYIxagBEgM5MjUYzUQg4Bgo3qf4AjDTqfgCOEtAAFgBcgVLT1dDTQomCMWoARIDODU5GOAYIKkLKO6q-AIws634AjhLQAFYAXIFS09XQ00SCggBEAEYASoCRVQYASIECAEQASgCKAQoBjAB) ![ASKY](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KP.gif) Sun, 21 Sept - Sat, 27 Sept NSI Yaoundé JNB Johannesburg £1,373 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:27/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1372.60&airProductToken=AQpYCioIy6ABEgI2ORjNRCCrsQEo4qT4AjCqpvgCOFZAAFgBagJQWHIFVlBYT1cKKgjLoAESAjc0GKuxASCpCyjop_gCMM2r-AI4VkABWAFqAlBYcgVWUFhPVxIKCAEQARgBKgJLUBgBIgQIARABKAIoBCgGMAE) ![Turkish Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TK.gif) Sun, 21 Sept - Fri, 26 Sept NSI Yaoundé JNB Johannesburg £1,738 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:NSI,to:JNB,departure:21/09/2025TANYT&leg2=from:JNB,to:NSI,departure:26/09/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1737.90&airProductToken=AQpZCisI1JYBEgM2NjgYzUQgyJwBKJOi-AIwy6X4AjhZQABYAWoCRlhyBVlMQk9XCioI1JYBEgI0MhjInAEgqQso-qv4AjDDsPgCOFlAAVgBagJGWHIFWUxCT1cSCggBEAEYASoCVEsYASIECAEQASgCKAQoBjAB) ## Travel information | Origin airport | Nsimalen Intl. | | --- | --- | | Destination airport | O.R. Tambo Intl. | | Airlines serving | Ethiopian Airlines, Turkish Airlines | | Return price | £883 | | Distance | 3751 km | ## Book with confidence ### Compare flights from Yaounde to Johannesburg easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Yaounde to Johannesburg. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to O.R. Tambo Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Nsimalen Intl. to O.R. Tambo Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Nsimalen Intl. (NSI) to O.R. Tambo Intl. (JNB) The easiest way to view the best deals on flights from Yaounde to Johannesburg today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Nsimalen Intl. to O.R. Tambo Intl. start at just £884 and range up to £1,738.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Yaounde and Johannesburg - booking your flight during December, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Yaounde to Johannesburg flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Nsimalen Intl. to O.R. Tambo Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. 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