A historic plaza with a fountain, trees, and a building with arches.

£156 Cheap Flights from Mexico City (MEX) to Santo Domingo (SDQ)

View £156 flight on Fri, 1 Jan 2027Opens in a new window

Popular airlines from Benito Juarez International Airport (MEX) to Las Americas Intl. Airport (SDQ)

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Cheap Flights from Mexico City (MEX) to Santo Domingo (SDQ)

Prices were available within the past 7 days and start at £156 for one-way flights and £322 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Thu, 3 Dec - Wed, 9 Dec
MEX
Mexico City
SDQ
Santo Domingo
£322 Return, found 3 days ago
£322
Return
found 3 days ago
Select Aeromexico flight, departing Thu, 3 Dec from Mexico City to Santo Domingo, returning Wed, 9 Dec, priced at £322 found 3 days ago
Copa
Thu, 29 Oct - Tue, 3 Nov
MEX
Mexico City
SDQ
Santo Domingo
£357 Return, found 4 days ago
£357
Return
found 4 days ago
Select Copa flight, departing Thu, 29 Oct from Mexico City to Santo Domingo, returning Tue, 3 Nov, priced at £357 found 4 days ago
avianca
Thu, 3 Dec - Wed, 9 Dec
MEX
Mexico City
SDQ
Santo Domingo
£388 Return, found 3 days ago
£388
Return
found 3 days ago
Select avianca flight, departing Thu, 3 Dec from Mexico City to Santo Domingo, returning Wed, 9 Dec, priced at £388 found 3 days ago
American Airlines
Mon, 7 Sept - Wed, 9 Sept
MEX
Mexico City
SDQ
Santo Domingo
£807 Return, found 7 hours ago
£807
Return
found 7 hours ago
Select American Airlines flight, departing Mon, 7 Sept from Mexico City to Santo Domingo, returning Wed, 9 Sept, priced at £807 found 7 hours ago
Delta
Sun, 6 Sept - Tue, 8 Sept
MEX
Mexico City
SDQ
Santo Domingo
£1,177 Return, found 7 hours ago
£1,177
Return
found 7 hours ago
Select Delta flight, departing Sun, 6 Sept from Mexico City to Santo Domingo, returning Tue, 8 Sept, priced at £1,177 found 7 hours ago
United
Tue, 1 Sept - Thu, 3 Sept
MEX
Mexico City
SDQ
Santo Domingo
£1,354 Return, found 5 days ago
£1,354
Return
found 5 days ago
Select United flight, departing Tue, 1 Sept from Mexico City to Santo Domingo, returning Thu, 3 Sept, priced at £1,354 found 5 days ago

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city centre is 22 minutes. Flights from £388
SDQ
Las Americas Intl.
Cheapest
Average driving time to city centre22 min
Flights from £388

Find the cheapest month to fly from Mexico City (MEX) to Santo Domingo (SDQ)

September is typically the cheapest month to fly

From £203 - £341 per traveller.

Frequently asked questions

How much does a flight from Mexico City (MEX-Mexico City Intl.) to Santo Domingo (SDQ-Las Americas Intl.) cost?
You can find one-way and return flights from MEX to SDQ with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when MEX to SDQ ticket fares go up or down.
What is the cheapest month to fly from Mexico City (MEX-Mexico City Intl.) to Santo Domingo (SDQ-Las Americas Intl.)?
The cheapest months to fly from MEX to SDQ are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Mexico City (MEX) to Santo Domingo (SDQ)?
Enter MEX to SDQ and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Mexico City (MEX) to Santo Domingo (SDQ)?
To find a cheap flight from Mexico City (MEX) to Santo Domingo (SDQ), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Mexico City (MEX-Mexico City Intl.) to Santo Domingo (SDQ-Las Americas Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Mexico City (MEX) to Santo Domingo (SDQ)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from Mexico City (MEX) to Santo Domingo (SDQ). To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from Mexico City (MEX-Mexico City Intl.) to Santo Domingo (SDQ-Las Americas Intl.)?
Direct flights from MEX to SDQ usually take about 4 hours 20 minutes, traveling roughly 3,092 kilometers. If you opt for a connecting flight, expect to add around 15 hours 30 minutes to your journey. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mexico City (MEX) to Santo Domingo (SDQ)?
Select the "Business class" and "First class" filters when looking for Mexico City (MEX) to Santo Domingo (SDQ) flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Mexico City (MEX) to Santo Domingo (SDQ) flight with Expedia?
It's easy to earn miles on a Mexico City (MEX) to Santo Domingo (SDQ) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
Is it cheaper to buy a plane ticket from Mexico City (MEX) to Santo Domingo (SDQ) at the last minute?
Typically, booking a last minute flight from Mexico City (MEX) to Santo Domingo (SDQ) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mexico City (MEX) to Santo Domingo (SDQ) flight and hotel package?
Securing a Mexico City (MEX) to Santo Domingo (SDQ) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mexico City (MEX) to Santo Domingo (SDQ)?
If you booked your Mexico City (MEX) to Santo Domingo (SDQ) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mexico City Intl.
Destination airport
Las Americas Intl.
Roundtrip price
£322
Distance
3073 km
Average flight time
4 hours 31 mins

Book with confidence

Compare flights from Mexico City to Santo Domingo easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Mexico City to Santo Domingo. Operating between them flights per day, 17 airlines cover the route. And fly direct, getting you to Las Americas Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Mexico City Intl. to Las Americas Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Mexico City Intl. (MEX) to Las Americas Intl. (SDQ)

The easiest way to view the best deals on flights from Mexico City to Santo Domingo today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Mexico City Intl. to Las Americas Intl. start at just £322 and range up to £1,354.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Mexico City and Santo Domingo
  • booking your flight during December, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Mexico City to Santo Domingo flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Mexico City Intl. to Las Americas Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from Mexico City to Santo Domingo easily and book with confidence

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