£267 Cheap Flights from Florence (FLR) to San Francisco (SFO)

View £267 flight on Thu, 20 Nov 2025Opens in a new window

Popular airlines from Peretola Airport (FLR) to San Francisco International Airport (SFO)

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 25% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Florence (FLR) to San Francisco (SFO)

Prices were available within the past 7 days and start at £267 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Find the cheapest month to fly from Florence (FLR) to San Francisco (SFO)

March is typically the cheapest month to fly

From £381 - £674 per traveller.

Graph displaying average flight prices per month

Flight from Florence to San Francisco route information
Origin airport
Peretola
Destination airport
San Francisco Intl.
Distance
9769 km

Compare flights from Florence to San Francisco easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from Florence to San Francisco. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Peretola to San Francisco Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Peretola (FLR) to San Francisco Intl. (SFO)

The easiest way to view the best deals on flights from Florence to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Peretola to San Francisco Intl. start at just and range up to .  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near Florence and San Francisco
  • booking your flight during , the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your Florence to San Francisco flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Peretola to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Frequently asked questions

How much is a flight from Peretola Airport (FLR) to SFO?
Based on fares offered within the last 7 days on Expedia for flights departing within the next year, round-trip journeys from FLR to SFO start from . Book ASAP to secure the best price for your journey. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Amerigo Vespucci Airport to San Francisco Intl. Airport (SFO)?
This differs from airline to airline, as each has its own set of terms and conditions. Visit the Customer Service Portal, where there are easy instructions on how to cancel online.
How do I find cheap flights from Amerigo Vespucci Airport to SFO that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Amerigo Vespucci Airport to SFO flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Amerigo Vespucci Airport to San Francisco Intl. Airport (SFO)?
With around 9,800 kilometres separating Florence and San Francisco, your flight will be a long one. Pack wisely and make your trip more comfortable. Little things like an extra pair of socks and a quality travel pillow should be in your hand luggage.
Which airlines fly direct from Amerigo Vespucci Airport to San Francisco Intl. Airport (SFO)?
Flying directly between Amerigo Vespucci Airport and San Francisco Intl. Airport (SFO) isn't possible at the moment. However, you'll still be able to find a flight to San Francisco with at least one stop.
Are Peretola Airport (FLR) to San Francisco Intl. Airport (SFO) flight tickets cheaper when they're purchased at the last minute?
It is possible to pick up great last-minute deals from Amerigo Vespucci Airport to San Francisco Airport, but it can also be hit-or-miss. As many airlines release prices up to a year in advance, it's worthwhile keeping an eye on fares early and being ready to pounce when you see a bargain. Expedia compares carrier prices and updates flight deals all the time, so you can rest assured you're always getting the latest offers.

Explore a world of travel with Expedia

*Available to Expedia members.