Beginning of main content

Family-Friendly Hotels in Tenderloin, San Francisco

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Tenderloin Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Tenderloin Family-Friendly Hotels

See all 617 Hotels in Tenderloin
COVA Hotel

COVA Hotel

655 Ellis Street, San Francisco
3.0 out of 5.0
3.6 out of 5 (431 reviews)
Comfortable and clean. Great ratio Quality/PriceClean rooms, comfortable stay, good breakfast. Very helpful and courteous staff. Great location.
  15 Jul 2017

£118

£118
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (1,522 reviews)
Excellent Location Clean rooms excellent location in UNion Square, nice & clean rooms. It can be good for vacation or business
  23 Jul 2017

£142

£142
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,537 reviews)
Old fashioned serviceVery convenient for Union Square although on the wrong side of the tracks ! Staff were very friendly and accommodating.
  24 Jul 2017

£150

£150
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
4.0 out of 5.0
3.9 out of 5 (2,914 reviews)
UnionesqueGreat rate for a great location-expect to walk. Hotel has multiple amenities that allow guests to seek comfort. The heated pool and spa helped a great deal after our daily journeys each day. Two adults and two female preteens-exceeded expectations. An added plus was staff checking to see how our ...
  23 Jul 2017

£192

£192
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

55 Cyril Magnin St, San Francisco
4.0 out of 5.0
4.2 out of 5 (4,269 reviews)
SF love and memories My wife and I come every year to SF and stay at Parc 55. This has been for the past 10 years. Love the location, hotel, staff and the room with a view of the city and bay. Glad they have refrigerators in the rooms! Recommendations: offer water stations, and offer free continental breakfast including ...
  23 Jul 2017

£164

£164
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,719 reviews)
great hotelNot our first stay at this wonderful hotel. Upgraded to a corner suite by the front desk crew, beautiful room. Had an electrical shirt that caused both bathrooms lights to fail. It corrected itself and we informed housekeeping. Housekeeping left a note that the problem was remedied, unfortunately, ...
  23 Jul 2017

£179

£179
King George Hotel

King George Hotel

334 Mason Street, San Francisco
3.0 out of 5.0
3.9 out of 5 (1,339 reviews)
Hidden fees, watch out!I book a room for my wife and son, and the hotel gave only one beed for all of us, even thouhg i have requested two beds The options: cacel the reservation and look for another hotel or pay for and extra fee 0f $40 per nigth in order to have to beeds..... what a rip off and costumer service level ...
  14 Jul 2017

£174

£174
Phoenix Hotel, a Joie de Vivre Boutique Hotel

Phoenix Hotel, a Joie de Vivre Boutique Hotel

601 Eddy St, San Francisco
2.5 out of 5.0
4.0 out of 5 (226 reviews)
Friendly Hotel Close to Interesting ThingsMy little girl and I take stay-cations here. It's a relaxed, friendly hotel with a rock and roll vibe. Nearby are the Asian Art Musuem, the Tenderloin Museum, the Main Library, five playgrounds, a farmers market a couple times a week, art galleries and many good restaurants.
  7 Jul 2017

£160

£160
Alexis Park Hotel

Alexis Park Hotel

825 Polk Street, San Francisco
2.0 out of 5.0
3.2 out of 5 (297 reviews)
Clean, updated rooms; helpful staffRooms were very clean and modern, beds were comfy, and A/C worked well. Keurig in the room was nice but the hair dryer was old and didn't blow out much air. The staff were excellent and friendly. Only downfall for the location; high homeless population in the area. I wouldn't walk alone in the area ...
  18 Jul 2017

£107

£107
Regency Inn

Regency Inn

587 Eddy St, San Francisco
2.0 out of 5.0
3.0 out of 5 (2 reviews)
Clean and Convenient Nice, clean large room and convenient. It would have been nice to have access to ice since they do not offer refrigerators. (I think the ice machine was broken but that issue should have lasted a day and it was not available the whole weekend.) My only words of caution are that there are a lot of ...
  17 Jul 2017

£114

£114
Map

Recently booked Tenderloin hotels

Hotel Metropolis
3.0 out of 5.0
Last booking: 6 minutes ago
Hilton San Francisco Union Square
4.0 out of 5.0
Last booking: 27 minutes ago
Clift
4.0 out of 5.0
Last booking: 30 minutes ago
King George Hotel
3.0 out of 5.0
Last booking: 1 hour ago
Parc 55 San Francisco - A Hilton Hotel
4.0 out of 5.0
Last booking: 1 hour ago
Hotel EPIK
3.5 out of 5.0
Last booking: 1 hour ago
Monarch Hotel
2.0 out of 5.0
Last booking: 1 hour ago
Alexis Park Hotel
2.0 out of 5.0
Last booking: 4 hours ago
Axiom Hotel San Francisco
4.0 out of 5.0
Last booking: 7 hours ago

Pocket Guide: Family-Friendly Hotels in Tenderloin

Search for hotels in Tenderloin on Expedia. You can easily find your hotels in Tenderloin using one of the methods below:

  • View our selection of featured hotels in Tenderloin
  • Use the map to find hotels in the Tenderloin neighborhood you prefer
  • Use the filters to see hotels in a specific area of Tenderloin, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Tenderloin
  • Enter your travel dates to view the best deals on hotels in Tenderloin - while they last