Title: The Best Hotels Closest to St. Lucie Medical Center in Port Saint Lucie - 2026 Updated Prices | Expedia.co.uk [St. Lucie Medical Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-St-Lucie-Medical-Center.d624555985155076096.Car-Hire-Guide)[St. Lucie Medical Center Holidays](https://expedia.co.uk/St-Lucie-Medical-Center-Sandhill-Crossing.d624555985155076096.Attraction) ![Palm Tree outside in the serenity garden. ](https://images.trvl-media.com/place/624555985155076096/d6ed917d-2eb7-4f8c-8e45-b341d24fd26e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Dean Moore ![](https://images.trvl-media.com/place/624555985155076096/d6ed917d-2eb7-4f8c-8e45-b341d24fd26e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [9 Feb - 10 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624555985155076096&startDate=2026-02-09&endDate=2026-02-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Feb - 11 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624555985155076096&startDate=2026-02-10&endDate=2026-02-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624555985155076096&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624555985155076096&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for St. Lucie Medical Center hotels ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/8400/8340/f9ddae07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/10000/8400/8340/d59107b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | 1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/10000/8400/8340/9a474b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8400/8340/074d5a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Port St. Lucie by IHG [](https://www.expedia.co.uk/Vero-Beach-Hotels-Holiday-Inn-Port-St-Lucie.h8340.Hotel-Information) Sandhill Crossing, 0.6 mi from St. Lucie Medical Center 6.8/10 (1,002 reviews) "The Staff was great very accommodating so friendly Hotel needs a refresh " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary £151 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Holiday-Inn-Port-St-Lucie.h8340.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/2089c3c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/8119d700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/4f12be86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/f818595e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Port St. Lucie [](https://www.expedia.co.uk/Vero-Beach-Hotels-Best-Western-Port-St-Lucie.h13549.Hotel-Information) 2.7 mi from St. Lucie Medical Center 8.6/10 Excellent (1,003 reviews) "Room was clean and breakfast was good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mario S £132 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Best-Western-Port-St-Lucie.h13549.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251411/b5b9c84e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251411/850cdb1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251411/fcf4ab57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251411/b461d934.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Stuart [](https://www.expedia.co.uk/Vero-Beach-Hotels-Home2-Suites-By-Hilton-Stuart.h48251411.Hotel-Information) 4.9 mi from St. Lucie Medical Center 9.4/10 Exceptional (625 reviews) "Very spacious room and tasty breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £144 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Home2-Suites-By-Hilton-Stuart.h48251411.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2220000/2212000/2211950/e8cf9efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2220000/2212000/2211950/76e06ec5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/3000000/2220000/2212000/2211950/e7c933d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/3000000/2220000/2212000/2211950/b8849de9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Stuart-North [](https://www.expedia.co.uk/Vero-Beach-Hotels-Hampton-Inn-Suites-Stuart-North.h2211950.Hotel-Information) 5.1 mi from St. Lucie Medical Center 8.8/10 Excellent (1,007 reviews) "Great service and breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clara £165 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Vero-Beach-Hotels-Hampton-Inn-Suites-Stuart-North.h2211950.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/13000000/12630000/12621700/12621664/02855d43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch TV with cable channels](https://images.trvl-media.com/lodging/13000000/12630000/12621700/12621664/26143826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/13000000/12630000/12621700/12621664/e782cde6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch TV with cable channels](https://images.trvl-media.com/lodging/13000000/12630000/12621700/12621664/57813b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Colorado Inn [](https://www.expedia.co.uk/Vero-Beach-Hotels-Old-Colorado-Inn.h12621664.Hotel-Information) 6.7 mi from St. Lucie Medical Center 9.8/10 Exceptional (693 reviews) "Beautiful spacious room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kellie [](https://www.expedia.co.uk/Vero-Beach-Hotels-Old-Colorado-Inn.h12621664.Hotel-Information) ![Room, 2 Queen Beds, Balcony, Ocean View | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/10000/9939/ba328d59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/1000000/10000/10000/9939/4513dc1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/10000/9939/ab6982c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/10000/9939/82ce7db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lucie [](https://www.expedia.co.uk/Jensen-Beach-Hotels-The-Lucie.h9939.Hotel-Information) 5.9 mi from St. Lucie Medical Center 9.0/10 Wonderful (1,010 reviews) "Steve was great and room with ocean side view was very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diego £197 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Jensen-Beach-Hotels-The-Lucie.h9939.Hotel-Information) ![Breakfast, lunch, dinner served; beach views ](https://images.trvl-media.com/lodging/18000000/17160000/17151300/17151251/2178a78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/18000000/17160000/17151300/17151251/049c70bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17160000/17151300/17151251/4daef4a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17160000/17151300/17151251/4856807c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hutchinson Shores Resort & Spa [](https://www.expedia.co.uk/Vero-Beach-Hotels-Hutchinson-Shores-Resort-Spa.h17151251.Hotel-Information) 6.6 mi from St. Lucie Medical Center 9.4/10 Exceptional (1,003 reviews) "Beautiful beach property and excellent staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) robin £294 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Hutchinson-Shores-Resort-Spa.h17151251.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/25200/25124/54987058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/25200/25124/c66a12ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25124/14a90e45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/25200/25124/cce346c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Fort Pierce Midtown [](https://www.expedia.co.uk/Vero-Beach-Hotels-Days-Inn-By-Wyndham-Fort-Pierce-Midtown.h25124.Hotel-Information) 8.4 mi from St. Lucie Medical Center 6.8/10 (1,003 reviews) "Checkin was easy and front desk lady was professional " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Betsy £74 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Days-Inn-By-Wyndham-Fort-Pierce-Midtown.h25124.Hotel-Information) ![On the beach](https://images.trvl-media.com/lodging/73000000/72130000/72125600/72125542/2fc9e759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/73000000/72130000/72125600/72125542/e434ce76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/73000000/72130000/72125600/72125542/9cb00068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LED TV](https://images.trvl-media.com/lodging/73000000/72130000/72125600/72125542/3268d9fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vistana Beach Club [](https://www.expedia.co.uk/Jensen-Beach-Hotels-Vistana-Beach-Club.h72125542.Hotel-Information) 5.7 mi from St. Lucie Medical Center 9.2/10 Wonderful (123 reviews) "Modern, spotless accomodations, very friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) S £328 includes taxes & fees 4 Mar - 5 Mar [](https://www.expedia.co.uk/Jensen-Beach-Hotels-Vistana-Beach-Club.h72125542.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/300000/296100/296064/a0b7ffaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/300000/296100/296064/e0670c8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/296100/296064/966601fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/300000/296100/296064/c2e50f36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mainstay Suites at PGA Village [](https://www.expedia.co.uk/Vero-Beach-Hotels-Mainstay-Suites-At-PGA-Village.h296064.Hotel-Information) 8 mi from St. Lucie Medical Center 6.4/10 (867 reviews) "Always nice place good stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) susan £84 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Mainstay-Suites-At-PGA-Village.h296064.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/79000000/78120000/78119400/78119323/8b9b027f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/79000000/78120000/78119400/78119323/c2db3138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, free WiFi](https://images.trvl-media.com/lodging/79000000/78120000/78119400/78119323/cacc19f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/79000000/78120000/78119400/78119323/c057f564.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Port St. Lucie Tradition [](https://www.expedia.co.uk/Port-Saint-Lucie-Hotels-Tru-By-Hilton-Port-St-Lucie.h78119323.Hotel-Information) Traditions, 8.4 mi from St. Lucie Medical Center 9.2/10 Wonderful (797 reviews) "Good place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor £141 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Port-Saint-Lucie-Hotels-Tru-By-Hilton-Port-St-Lucie.h78119323.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/20000/19950/8c515b21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/20000/19950/e2922ee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Courtyard View | View from room](https://images.trvl-media.com/lodging/1000000/20000/20000/19950/aa33a252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/20000/19950/62144dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Downtown Stuart [](https://www.expedia.co.uk/Vero-Beach-Hotels-Best-Western-Downtown-Stuart.h19950.Hotel-Information) 7.5 mi from St. Lucie Medical Center 8.6/10 Excellent (1,006 reviews) "Everything was great, good breakfast too" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ana £147 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Best-Western-Downtown-Stuart.h19950.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/90000000/89180000/89176800/89176717/d27101dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe 1-Bedroom Two Double w/ Kitchen & Sofa Bed | Living room | 42-inch Smart TV with satellite channels, TV, Netflix](https://images.trvl-media.com/lodging/90000000/89180000/89176800/89176717/5659dcfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe 1-Bedroom King w/ Kitchen & Sofa Bed | Living area | 42-inch Smart TV with satellite channels, TV, Netflix](https://images.trvl-media.com/lodging/90000000/89180000/89176800/89176717/5fc60725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Ground Floor 1-Bedroom King w/ Kitchen & Sofa Bed | Terrace/patio](https://images.trvl-media.com/lodging/90000000/89180000/89176800/89176717/1a2b452e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverwatch Apartments by Lowkl [](https://www.expedia.co.uk/Jensen-Beach-Hotels-Riverwatch.h89176717.Hotel-Information) 6.2 mi from St. Lucie Medical Center 8.8/10 Excellent (176 reviews) "Great place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alfred £145 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Jensen-Beach-Hotels-Riverwatch.h89176717.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/870000/860400/860330/98722c9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/870000/860400/860330/8fdf5ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/860400/860330/7d0a569c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/870000/860400/860330/3a172b14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Port St. Lucie, West [](https://www.expedia.co.uk/Vero-Beach-Hotels-Hampton-Inn-Suites-Port-St-Lucie.h860330.Hotel-Information) 7.1 mi from St. Lucie Medical Center 9.0/10 Wonderful (1,009 reviews) "Room was spacious and clean, staff were great breakfast was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eddie £182 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Hampton-Inn-Suites-Port-St-Lucie.h860330.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/3000000/2340000/2333500/2333441/f9a80b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2340000/2333500/2333441/442d069b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2340000/2333500/2333441/085f58a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2340000/2333500/2333441/58b0c350.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Port St. Lucie [](https://www.expedia.co.uk/Vero-Beach-Hotels-Residence-Inn-By-Marriott-Port-St-Lucie.h2333441.Hotel-Information) 7.3 mi from St. Lucie Medical Center 9.0/10 Wonderful (1,001 reviews) "It was really nice stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vishal £230 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Residence-Inn-By-Marriott-Port-St-Lucie.h2333441.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/45000000/44270000/44267500/44267426/6a2d603a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/45000000/44270000/44267500/44267426/e9463251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/45000000/44270000/44267500/44267426/1275409e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/45000000/44270000/44267500/44267426/4f155301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Stuart - Hutchinson Island [](https://www.expedia.co.uk/Vero-Beach-Hotels-Comfort-Suites-Stuart-Hutchinson-Island.h44267426.Hotel-Information) 9.7 mi from St. Lucie Medical Center 9.6/10 Exceptional (1,014 reviews) "The hotel was spotless! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cindy £166 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Comfort-Suites-Stuart-Hutchinson-Island.h44267426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102000/101904/79ea3410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/110000/102000/101904/02b6ac04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/110000/102000/101904/e8bda46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/102000/101904/6445c0d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites Port St. Lucie [](https://www.expedia.co.uk/Vero-Beach-Hotels-SpringHill-Suites-Port-St-Lucie.h101904.Hotel-Information) Saint Lucie West, 7.3 mi from St. Lucie Medical Center 8.6/10 Excellent (1,006 reviews) " Room was clean and the staff very accommodating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £184 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-SpringHill-Suites-Port-St-Lucie.h101904.Hotel-Information) ![Superior Suite, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/27800/27738/ff1f1518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/30000/27800/27738/bb3816d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/27800/27738/1ba2dbb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27800/27738/87c40947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Stuart [](https://www.expedia.co.uk/Vero-Beach-Hotels-Days-Inn-By-Wyndham-Stuart.h27738.Hotel-Information) 7.5 mi from St. Lucie Medical Center 6.6/10 (1,007 reviews) "Staff was fast, efficient, and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £111 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Days-Inn-By-Wyndham-Stuart.h27738.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/68000000/67580000/67573600/67573501/30bfb5cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/68000000/67580000/67573600/67573501/024242b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/68000000/67580000/67573600/67573501/4af6785e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/68000000/67580000/67573600/67573501/cd07c8cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Port St. Lucie Tradition [](https://www.expedia.co.uk/Vero-Beach-Hotels-Courtyard-By-Marriott-Port-St-Lucie-Tradition.h67573501.Hotel-Information) Traditions, 8.4 mi from St. Lucie Medical Center 9.4/10 Exceptional (507 reviews) "Great hotel and staff is friendly and kind " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lilett £217 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-Courtyard-By-Marriott-Port-St-Lucie-Tradition.h67573501.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/43000000/42070000/42061500/42061470/f7c914bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/43000000/42070000/42061500/42061470/f65e38ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42070000/42061500/42061470/2e6098b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/43000000/42070000/42061500/42061470/171e4ced.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Port St. Lucie I-95 [](https://www.expedia.co.uk/Vero-Beach-Hotels-TownePlace-Suites-By-Marriott-Port-St-Lucie-I-95.h42061470.Hotel-Information) Traditions, 8.4 mi from St. Lucie Medical Center 9.4/10 Exceptional (1,005 reviews) "Clean hotel and comfortable rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kippi £207 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Vero-Beach-Hotels-TownePlace-Suites-By-Marriott-Port-St-Lucie-I-95.h42061470.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-23&endDate=2026-02-24®ionId=624555985155076096&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to St. Lucie Medical Center | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/8400/8340/f9ddae07.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Port St. Lucie by IHG | 3.0 star property | 6.81,002 reviews | View | | | | | | | ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/2089c3c4.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Best Western Port St. Lucie | 2.5 star property | 8.6Excellent1,003 reviews | View | | | | | | | ![Property grounds](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251411/b5b9c84e.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Home2 Suites by Hilton Stuart | 3.0 star property | 9.4Exceptional625 reviews | View | | | | | | | ![Property amenity](https://images.trvl-media.com/lodging/3000000/2220000/2212000/2211950/e8cf9efd.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Stuart-North | 2.5 star property | 8.8Excellent1,007 reviews | View | | | | | | | ![Interior detail](https://images.trvl-media.com/lodging/13000000/12630000/12621700/12621664/02855d43.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Old Colorado Inn | 3.5 star property | 9.8Exceptional693 reviews | View | | | | | | ## Top St. Lucie Medical Center Hotel Reviews ![Paradise Palms 2](https://images.trvl-media.com/lodging/100000000/99690000/99687800/99687737/w507h683x259y0-1616323b_y.jpg) ### Paradise Palms 2 10/10 Excellent "WE stay at VRBO rentals often. I can tell you that he is an extraordinary, kind, attentive host. The house was immaculate. We had a very comfortable one month's stay. Our host, Neil, pointed out an osprey nest and we were big fans (geeks) of daily bird watching. The neighborhood was lovely. There was a dog in the house behind ours and we occasionally hurt a little bit of barking but nothing annoying. One of the great things in this home was an entire coffee bar, actually kind of a breakfast bar because there was oatmeal provided as well as a variety of coffee, tea, hot chocolate and even popcorn. In one of the closets there was a variety of games which was nice to have. Check in and check out was easy. We would definitely stay again. Very grateful to spend the entire month of January in this lovely home." [](https://expedia.co.uk/Port-Saint-Lucie-Hotels-Paradise-Palms-2.h99687737.Hotel-Information) ![Best Western Port St. Lucie](https://images.trvl-media.com/lodging/1000000/20000/13600/13549/0302e69f_y.jpg) ### Best Western Port St. Lucie 10/10 Excellent "Everything was clean and the breakfast was good . " [](https://expedia.co.uk/Vero-Beach-Hotels-Best-Western-Port-St-Lucie.h13549.Hotel-Information) ![Charming 3-bedroom house with AC, fitness room, WiFi in Port St. Lucie](https://images.trvl-media.com/lodging/110000000/109460000/109459800/109459771/af40ca67_y.jpg) ### Charming 3-bedroom house with AC, fitness room, WiFi in Port St. Lucie 10/10 Excellent "Great experience " [](https://expedia.co.uk/Charming-3-Bedroom-House-With-AC.h109459771.Hotel-Information) ![Holiday Inn Port St. Lucie by IHG](https://images.trvl-media.com/lodging/1000000/10000/8400/8340/e6e4b7d2_y.jpg) ### Holiday Inn Port St. Lucie by IHG 10/10 Excellent "Perfect " [](https://expedia.co.uk/Vero-Beach-Hotels-Holiday-Inn-Port-St-Lucie.h8340.Hotel-Information) ![Private Heated Pool, Tropical Breezes from the Ocean, Only 10 Minutes to Beach!](https://images.trvl-media.com/lodging/20000000/19080000/19070900/19070853/a3b11efc_y.jpg) ### Private Heated Pool, Tropical Breezes from the Ocean, Only 10 Minutes to Beach! 10/10 Excellent "We absolutely enjoyed our stay and were totally satisfied with the home. The host defiantly responded quickly to any questions we had, and the home was well stocked with supplies and even a little something extra for us as guests. " [](https://expedia.co.uk/Vero-Beach-Hotels-Private-Heated-Pool.h19070853.Hotel-Information) ![voco Sandpiper All Inclusive Resort by IHG](https://images.trvl-media.com/lodging/1000000/910000/908100/908079/45b19f4d_y.jpg) ### voco Sandpiper All Inclusive Resort by IHG 10/10 Excellent "Everyone went above and beyond Rooms are spacious and the meals are delicious 😋 " [](https://expedia.co.uk/Port-Saint-Lucie-Hotels-Voco-Sandpiper-All-Inclusive-Resort-By-IHG.h908079.Hotel-Information) ![Relaxing 2BR Home with Office + Garden - 10 Min to Beach & Family Friendly](https://images.trvl-media.com/lodging/118000000/117650000/117642900/117642899/6c992047_y.jpg) ### Relaxing 2BR Home with Office + Garden - 10 Min to Beach & Family Friendly 10/10 Excellent "Awesome all around. " [](https://expedia.co.uk/Port-Saint-Lucie-Hotels-Relaxing-2BR-Home-With-Office-Garden-10-Min-To-Beach-Family-Friendly.h117642899.Hotel-Information) ![Sandhill House Port St. Lucie, Sandhill House Port St. Lucie - A family retreat near Jensen Beach](https://images.trvl-media.com/lodging/97000000/96170000/96162500/96162405/82b5d2c2_y.jpg) ### Sandhill House Port St. Lucie, Sandhill House Port St. Lucie - A family retreat near Jensen Beach 10/10 Excellent "Everything was clean and in good repair. Very quiet and comfortable." [](https://expedia.co.uk/Port-Saint-Lucie-Hotels-Sandhill-House-Port-St-Lucie-A-Family-Retreat-Only-Minutes-To-Jensen-Beach.h96162405.Hotel-Information) ![Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie](https://images.trvl-media.com/lodging/113000000/112540000/112538400/112538329/757b0425_y.jpg) ### Charming 3 bedroom & 2 Bathroom house with AC & WiFi in delightful Port St Lucie 10/10 Excellent "The property was just as advertised. It was just what we needed." [](https://expedia.co.uk/Port-Saint-Lucie-Hotels-Charming-3-Bedroom-2-Bathroom-House-With-AC-WiFi-In-Delightful-Port-St-Lucie.h112538329.Hotel-Information) ## Hotels near other St. Lucie Medical Center attractions ![Drone photography of Veterans Memorial Park in Oldsmar, Florida, a waterside park featuring a memorial, a bocce court, fitness equipment, trails, and a gazebo in Tampa Bay](https://images.trvl-media.com/place/553248621587339617/ce9cf026-434e-4dec-bedf-7f22373f116d.jpg) ### Veterans Memorial Park 4.2/5 (62 reviews) You can find out about the history of Port Saint Lucie when you stop by Veterans Memorial Park. Stroll along the beautiful beaches or attend a sporting event in this culturally rich area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621587339617) ![View over Fort Pierce Inlet State Park on the Treasure Coast of Florida in St. Lucie County ](https://images.trvl-media.com/place/553248621533115897/e589795a-1532-4da7-945b-e523fa6e1895.jpg) ### St Lucie Inlet State Park 4.5/5 (15 reviews) Find out about the history of Jensen Beach with a stop at St Lucie Inlet State Park. Wander through the beautiful beaches and waterfront in this culturally rich area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621533115897) ![River Park Marina in Port St Lucie](https://images.trvl-media.com/place/553248621587339619/14d4ec9f-578b-4e12-9cb1-2d1ffa28607d.jpg) ### River Park Marina River Park Marina is just one of the places to see in Port Saint Lucie, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or attend a sporting event in this culturally rich area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621587339619) ### The Saints at Port St. Lucie Golf Course 4.1/5 (75 reviews) Enjoy a round of golf in Port Saint Lucie at The Saints at Port St. Lucie Golf Course. Wander through the waterfront and beautiful beaches in this culturally rich area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6321264) ### Port St. Lucie Botanical Gardens 4.2/5 (114 reviews) Explore the lovely green spaces of Port St. Lucie Botanical Gardens and enjoy the golf courses in Port Saint Lucie. Amble around this family-friendly area's waterfront or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532653123) ### Walton Scrub Preserve Explore the great outdoors at Walton Scrub Preserve, a lovely green space in Fort Pierce. Amble around this culturally rich area's beautiful beaches or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621587477394) ### Eagle Marsh Golf Club 4.3/5 (8 reviews) Enjoy a round of golf in Jensen Beach at Eagle Marsh Golf Club. Wander through the beautiful beaches and waterfront in this culturally rich area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621587477405) ## Frequently asked questions ### What's the area like around St. Lucie Medical Center? ### Where is the best place to stay close to St. Lucie Medical Center? ### How many hotels should I expect to find close to St. Lucie Medical Center? ### If I need to cancel the hotel reservation for my stay near St. Lucie Medical Center, will I receive a refund? ### What can I see and do near St. Lucie Medical Center?