The Best Hotels Closest to St. Louis Science Center in St. Louis - 2026 Updated Prices

A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

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Our top choices for St. Louis Science Center hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A snack and treat display with various products, including chips and beverages, in a store setting.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

1. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 0.6 mi from St. Louis Science Center

Jennifer

£123

includes taxes & fees

5 Oct - 6 Oct

A lobby with a reception desk, seating area, and a bicycle in the background.

A spacious dining area with multiple tables and chairs, a kitchen area, and a flat-screen TV mounted on the wall.

2. Drury Inn & Suites St. Louis Forest Park

1.3 mi from St. Louis Science Center

Robert

£131

includes taxes & fees

12 Oct - 13 Oct

A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

A modern hotel lobby with a marble reception desk, a bar area, and a seating space.

A hotel with a modern facade, large windows, and a sign reading "AC HOTEL CENTRAL WEST END".

A modern living room with a fireplace, comfortable seating, and a large TV.

3. AC Hotel St. Louis Central West End

Central West End, 1.1 mi from St. Louis Science Center

Molly

£128

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio area with seating, planters, and a grill.

A spacious lobby with a modern design, featuring a seating area with sofas and armchairs, a reception desk, and a large window providing a view of the interior.

A modern hotel lobby with grey sofas, a coffee table, and a reception desk.

A building with a sign that reads "element by Westin" on a brick wall.

4. Element by Marriott St. Louis Midtown

Midtown, 1.7 mi from St. Louis Science Center

Heather

£116

includes taxes & fees

15 Oct - 16 Oct

An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

A hotel with a covered outdoor seating area, a parking lot, and a sign for a restaurant.

A modern cafe interior with a bar area, seating, and a menu board.

A modern bar area with a long counter, bar stools, and a television mounted on the wall.

5. Hotel Indigo St Louis - Central West End by IHG

Central West End, 1.1 mi from St. Louis Science Center

Lydia

£128

includes taxes & fees

4 Oct - 5 Oct

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

A spacious lobby with grey sofas, wooden coffee tables, and potted plants.

A building with a brick facade, a covered entrance, and a tree adorned with string lights.

A spacious dining area with marble tables and chairs, a kitchen in the background, and a modern ceiling design.

6. The West End

Central West End, 1.4 mi from St. Louis Science Center

Deborah

£79

includes taxes & fees

7 Oct - 8 Oct

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

A hotel room with a bed, a pink sofa, a small table, and a chair. There is a window with a view of a building.

A hotel coffee shop with a coffee machine, mugs, and a buffet area.

A compact kitchen with a stainless steel microwave, a sink, and a coffee maker.

7. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 0.5 mi from St. Louis Science Center

paullita jeanne

£137

includes taxes & fees

4 Oct - 5 Oct

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

A spacious lobby with leather sofas, a patterned rug, and a reception desk.

A modern living room with a flat-screen TV, a sofa, a coffee table, and a kitchen area with a refrigerator and cabinets.

A modern kitchen with wooden cabinets, a central island, and a wall display of packaged goods.

8. DoubleTree by Hilton St. Louis Forest Park

Central West End, 0.8 mi from St. Louis Science Center

Kevin

£135

includes taxes & fees

12 Oct - 13 Oct

A spacious foyer with a grand staircase, a piano, and a large rug.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.

A hallway with wooden doors, a wall-mounted tree decoration, a small table with a plant, and a painting.

9. White House at Grand Central

1.8 mi from St. Louis Science Center

Triman

£96

includes taxes & fees

4 Oct - 5 Oct

A bedroom with a large bed, a mirror, and a vanity with shelves.

A wall with a large, abstract mirror design.

A room with a grand piano, a round table with a red and white tablecloth, and a statue of a robed figure.

A modern bedroom with a large bed, a sitting area with a sofa and chairs, a vanity with a mirror, and a ceiling fan.

10. Central West End B&B

Central West End, 1.9 mi from St. Louis Science Center

Stacee

£145

includes taxes & fees

10 Oct - 11 Oct

A hotel room with two beds, a chair, a desk, and a large window.

A conference room with a floral carpet, tables with chairs, and a large orange pendant light.

A reception desk with a sign reading "Forest Park Hotel" and a clock on the wall.

A lobby with seating areas, a reception desk, and a view through glass doors.

11. Forest Park Hotel by MDR

The Hill, 1.1 mi from St. Louis Science Center

Janice

£72

includes taxes & fees

28 Oct - 29 Oct

A hotel room with a desk, a television, a bed, a mirror, and a coffee maker.

A Red Roof Plus hotel lobby with two leather chairs, a coffee station, and a sign indicating free Wi-Fi in all rooms.

A Red Roof Plus hotel with a stone facade, a parking lot, and a covered outdoor area.

A reception area with a counter, a clock, and a sign indicating free Wi-Fi availability.

12. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

The Hill, 1.1 mi from St. Louis Science Center

Sean

£67

includes taxes & fees

25 Oct - 26 Oct

A room with a green armchair, a round table, a lamp, and a mirror on the wall.

A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

A two-story building with a dark entrance, large windows, and a brick facade.

A bar area with a neon sign, a lamp, and various food and drink items.

13. Truitt Hotel

Lafayette Square, 3.1 mi from St. Louis Science Center

Gabrielle

£154

includes taxes & fees

30 Sept - 1 Oct

A rooftop terrace with wicker furniture, offering a city view.

A modern hotel lobby with a bar area, seating arrangements, and a large chandelier.

A spacious lobby with a blue sofa, a glass coffee table, and a chandelier.

A lobby with seating areas, a chandelier, and a large pillar.

14. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 4.4 mi from St. Louis Science Center

Salvatore

£119

includes taxes & fees

8 Oct - 9 Oct

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A spa bath with a sign indicating a capacity of 8 persons.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

15. Drury Plaza Hotel St. Louis Brentwood

4 mi from St. Louis Science Center

Janell

£122

includes taxes & fees

4 Oct - 5 Oct

A log cabin with a stone chimney, wooden deck, and a staircase leading to the entrance.

A rustic wooden bed with a quilt, a chair, and a view of the outdoors through a door.

A stone fireplace with a wooden mantel, surrounded by rustic decor and a wooden ceiling.

A rustic wooden interior with a wooden bench displaying various animal carvings and a stone wall.

16. The Lodge at Grant's Trail

6.3 mi from St. Louis Science Center

Patricia

£151

includes taxes & fees

12 Oct - 13 Oct

A modern hotel lobby with a glass facade, seating area, and a staircase.

A couple relaxing by a window overlooking a bridge and water.

A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

17. Four Seasons Hotel St Louis

4.7 mi from St. Louis Science Center

Nicole

£331

includes taxes & fees

12 Oct - 13 Oct

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

A hotel room with a four-poster bed, a dining table with chairs, a bedside table with lamps, and a floral-patterned rug.

A hallway with a chandelier, a dining table with chairs, and a vase of flowers.

A wooden table set for a meal under a tent with string lights, surrounded by chairs on a grassy area.

18. Grand Center Inn

2.2 mi from St. Louis Science Center

Leon and Janis

£150

includes taxes & fees

7 Oct - 8 Oct

An outdoor patio with a fire pit, seating, and a building in the background.

A Courtyard by Marriott hotel with a modern facade, multiple floors, and a well-lit entrance.

A modern bar area with a wooden counter, a beverage dispenser, and a menu board.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

19. Courtyard by Marriott St. Louis Brentwood

3.4 mi from St. Louis Science Center

Aaron

£109

includes taxes & fees

11 Oct - 12 Oct

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

A modern lounge area with a stone wall, a flat-screen TV, a fireplace, and comfortable seating.

A modern living room with a fireplace, a large forest-themed painting, and a cozy seating area with a sofa and a coffee table.

A modern dining area with multiple tables and chairs, a counter, and pendant lighting.

20. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 3.1 mi from St. Louis Science Center

James

£112

includes taxes & fees

7 Oct - 8 Oct

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Compare popular hotels close to St. Louis Science Center

Property	Property class	Guest rating
Hampton Inn & Suites St. Louis at Forest Park	9.4 Exceptional 1,006 reviews	View
Drury Inn & Suites St. Louis Forest Park	9.4 Exceptional 1,018 reviews	View
AC Hotel St. Louis Central West End	9.0 Wonderful 852 reviews	View
Element by Marriott St. Louis Midtown	8.8 Excellent 829 reviews	View
Hotel Indigo St Louis - Central West End by IHG	8.8 Excellent 1,005 reviews	View

Top St. Louis Science Center Hotel Reviews

Hampton Inn & Suites St. Louis at Forest Park

8/10 Good

"Great stay! Clean, safe hotel in a great location. Helpful staff and good breakfast! We'll stay again!!"

Cielo Casa on “The Hill” Walkable and mins away from, BJC, SLU, Downtown + more

10/10 Excellent

"We loved our stay! This home had everything we needed, including a private fenced-in yard. The location was perfect—within walking distance of The Hill and just a quick drive to the Arch and Forest Park. The home was comfortable, convenient, and in a great location. We would definitely stay here again!"

Forest Park Hotel by MDR

8/10 Good

"I was only there to sleep and did not use any of the amenities. The noise from the highway and the trains was louder than at most hotels I have stayed at."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"Relaxing night unwinding on rooftop bar."

The West End

8/10 Good

"It was a comfortable quiet room. Didn't care for the shower. TV didn't allow access to many channels. Not sure why. But for the most part enjoyed our stay."

DoubleTree by Hilton St. Louis Forest Park

8/10 Good

"Safe surroundings and ambiance. Access to restaurant from Lobby convenient. The bathroom was not completely clean specifically the bathtub. The rest of the room was great"

beautiful small house

10/10 Excellent

"The house was very nice and super clean and had everything you need and the neighborhood was super quiet. Maria was extremely nice and was very prompt on assisting us with any questions we had. The house is also located with everything close by and only 11 mins from downtown St. Louis. I will definitely stay again next time im in the area. And will definitely suggest to anyone i know headed to the area. Much better than any hotel. BIG THANKS MARIA."

4BR Near Forest Park Zoo & Missouri Botanical Garden | Free Parking | STL

10/10 Excellent

"We had a wonderful time. We were here for a wedding at the Wild Carrot and a pre wedding picnic at Tower Grove park so the location is perfect. We walked to the Science Center. Beds were comfortable and plentiful. I loved having plenty of towels available for all of us. The kitchen had all the dishes, etc that we needed. Everything was clean and inviting. If we are ever back in St. Louis, we certainly would choose this house again. Thank you for helping make our stay comfortable!"

Casa Esma on The Hill - Luxury Couples Retreat w/ Private Hot Tub

10/10 Excellent

"Centralized location with plenty of room and a fenced yard for your furry friends. Close to the hill and walking distance to some amazing restaurants. Host was very responsive and had plenty of ideas for our first visit to the area. Quick drive to the arch and downtown as well union Station and other attractions."

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.

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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

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A gazebo with columns and a dome roof, surrounded by a pond and greenery.

Pagoda Circle

As one of the cornerstones of Forest Park for about a century, this grassy island and its bandstand offer an excellent concert spot.

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A theater stage with a variety of neon signs advertising different businesses.

The Muny Theater

8.6/10 (7 reviews)

You can get tickets for a performance at The Muny Theater during your trip to St. Louis. Amble around the area's lush forest or attend a sporting event.

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Highlands Golf & Tennis Center

Catch an event at Highlands Golf & Tennis Center during your trip to St. Louis. Experience the area's entertainment choices or attend a baseball game.

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Atomic Cowboy

Atomic Cowboy is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

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Atomic by Jamo

Atomic by Jamo is just one of the places to see in St. Louis, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around St. Louis Science Center?

St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, take a look at the 72 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near St. Louis Science Center?

Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good choices within a short distance include Home2 Suites by Hilton St. Louis/Forest Park and DoubleTree by Hilton St. Louis Forest Park.

How many hotels should I expect to find close to St. Louis Science Center?

Expedia has 72 hotels and other accommodation options within a mile from St. Louis Science Center.

If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals near St. Louis Science Center.

What can I see and do near St. Louis Science Center?

Cathedral Basilica of St. Louis, St. Louis Art Museum and City Museum feature captivating exhibits. St. Louis Union Station, Jewel Box and Sheldon Concert Hall are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater and Powell Symphony Hall.

Search Hotels Near St. Louis Science Center, St. Louis

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Our top choices for St. Louis Science Center hotels

1. Hampton Inn & Suites St. Louis at Forest Park

2. Drury Inn & Suites St. Louis Forest Park

3. AC Hotel St. Louis Central West End

4. Element by Marriott St. Louis Midtown

5. Hotel Indigo St Louis - Central West End by IHG

6. The West End

7. Home2 Suites by Hilton St. Louis/Forest Park

8. DoubleTree by Hilton St. Louis Forest Park

9. White House at Grand Central

10. Central West End B&B

11. Forest Park Hotel by MDR

12. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave

13. Truitt Hotel

14. Drury Plaza Hotel St. Louis at the Arch

15. Drury Plaza Hotel St. Louis Brentwood

16. The Lodge at Grant's Trail

17. Four Seasons Hotel St Louis

18. Grand Center Inn

19. Courtyard by Marriott St. Louis Brentwood

20. Fairfield Inn & Suites by Marriott St. Louis Downtown

Compare popular hotels close to St. Louis Science Center

Top St. Louis Science Center Hotel Reviews

Hampton Inn & Suites St. Louis at Forest Park

Cielo Casa on “The Hill” Walkable and mins away from, BJC, SLU, Downtown + more

Forest Park Hotel by MDR

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

The West End

DoubleTree by Hilton St. Louis Forest Park

beautiful small house

4BR Near Forest Park Zoo & Missouri Botanical Garden | Free Parking | STL

Casa Esma on The Hill - Luxury Couples Retreat w/ Private Hot Tub

Other attractions near St. Louis Science Center

Jewel Box

Forest Park

Pagoda Circle

The Muny Theater

Highlands Golf & Tennis Center

Atomic Cowboy

Atomic by Jamo

Frequently asked questions