Title: Hotels in St. Ann, MO - Best St. Ann Hotels from £52 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in St. Ann](https://expedia.co.uk/St-Ann-Holiday-Rentals.d7051.Travel-Guide-HolidayRentals)[St. Ann Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-St-Ann.d7051.Car-Hire-Guide)[St. Ann Holidays](https://expedia.co.uk/St-Ann.d7051.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in St. Ann, MO from £52 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in St. Ann Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&lodging=APART_HOTEL) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&travelerType=family_friendly) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&lodging=APARTMENT) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&amenities=PETS) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&lodging=COTTAGE) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&lodging=CONDO) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&amenities=WATER_PARK) Villa [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&lodging=VILLA) ## Check prices for these dates Tonight [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=7051&startDate=2026-01-11&endDate=2026-01-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=7051&startDate=2026-01-12&endDate=2026-01-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=7051&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=7051&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for St. Ann hotels ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/e043dfbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/f94bc4e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/8337bebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/4f4ebed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham St. Louis Airport [](https://www.expedia.co.uk/St-Louis-Hotels-Wingate-By-Wyndham-St-Louis-Airport.h18172.Hotel-Information) St. Ann 9.2/10 Wonderful (1,505 reviews) "Pleasant atmosphere and very clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon Fohey £95 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Wingate-By-Wyndham-St-Louis-Airport.h18172.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Refrigerator & Microwave | Desk, blackout curtains, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/30c70db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/68c9f9ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/1ed98bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Airport [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) St. Ann 9.4/10 Exceptional (2,780 reviews) "Staff was great and breakfast and lobby was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheila £79 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/65a6e602.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/e4de4f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/22ea7c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency St. Louis at The Arch [](https://www.expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) Downtown St. Louis 8.4/10 Very good (4,042 reviews) "The staff was great and everything was clean. The breakfast was delicious and our room had an Arch view! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jordan £110 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/45000000/44010000/44005400/44005380/f0d9e7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/45000000/44010000/44005400/44005380/4694740e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/45000000/44010000/44005400/44005380/fd79d4c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/45000000/44010000/44005400/44005380/f4a32958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott St. Louis Downtown [](https://www.expedia.co.uk/St-Louis-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Louis-Downtown.h44005380.Hotel-Information) Downtown West 9.2/10 Wonderful (1,001 reviews) "Room was great! Staff were nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Delaney £95 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/St-Louis-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Louis-Downtown.h44005380.Hotel-Information) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/d9447723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/28e7b062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/82394016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/b1700171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites O'Fallon MO - Technology Drive [](https://www.expedia.co.uk/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information) O'Fallon 9.0/10 Wonderful (1,005 reviews) "Very good place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jasur £68 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information) ![Indoor pool, open 6:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/1be78cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/ee08c8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/f9a1bbed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/e72c213d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Louis-Downtown (At the Gateway Arch) [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Gateway-Arch-Downtown.h22520.Hotel-Information) Downtown St. Louis 8.8/10 Excellent (1,215 reviews) "Staff was great and the hotel was in a good location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Candi £85 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Gateway-Arch-Downtown.h22520.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/aab55c71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with cable channels, TV, pay films](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/d4863c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/59eb7f83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/6c45fcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Pennywell St. Louis at the Arch [](https://www.expedia.co.uk/St-Louis-Hotels-Hilton-St-Louis-Downtown-At-The-Arch.h1152198.Hotel-Information) Downtown St. Louis 8.8/10 Excellent (1,024 reviews) "Beautiful hotel, very clean. Dinner at restaurant was subpar. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa £94 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Hilton-St-Louis-Downtown-At-The-Arch.h1152198.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/50700/50618/d9039e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50700/50618/2fe11ed8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/60000/50700/50618/2cee3072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/60000/50700/50618/637eb874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Select St. Louis Airport [](https://www.expedia.co.uk/St-Louis-Hotels-Best-Western-Plus-St-Louis-Airport-Hotel.h50618.Hotel-Information) Woodson Terrace 9.2/10 Wonderful (1,001 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leon £106 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Best-Western-Plus-St-Louis-Airport-Hotel.h50618.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41500/41474/90e658d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41474/60f81807.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41500/41474/3d25ebf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41474/bd8d8775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Airport [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Airport.h41474.Hotel-Information) Edmundson 9.2/10 Wonderful (1,113 reviews) "Clean room, nice staff, great happy hour and breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeannette £93 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Airport.h41474.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/b53f4594.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/aadfb5be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking | Living area | LCD TV](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/49aae62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/c9087452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) Fenton 8.0/10 Very good (1,071 reviews) "Rooms were good qnd clean, beds were comfortable and staff was very nice and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel £73 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15900/15877/fb5db61c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15900/15877/c7d7e20e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15900/15877/e883a2bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/15900/15877/51002e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Convention Center [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Convention-Center.h15877.Hotel-Information) Downtown St. Louis 9.0/10 Wonderful (1,070 reviews) "The staff was great, the amenities were fantastic, and it was close to everything we needed! 10/10 stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dena £82 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Convention-Center.h15877.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/3e253a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/7320679c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/115e2f73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel [](https://www.expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) Downtown St. Louis 8.8/10 Excellent (1,190 reviews) "Wonderful stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £86 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d41360b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/721547ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/4e0535c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Refrigerator & Microwave | Living area | 50-inch flat-screen TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/929e2f03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton St. Louis Downtown [](https://www.expedia.co.uk/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information) Downtown St. Louis 8.8/10 Excellent (1,272 reviews) "Very cool hotel, rooms were clean and nice design, the food at the bar/restaurant was fantastic!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cullin £97 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports bar](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/e91217d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/a7d1479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool, open 10:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clayton Plaza Hotel & Extended Stay [](https://www.expedia.co.uk/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) Clayton 8.8/10 Excellent (3,068 reviews) "Great stay‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Calvin £82 includes taxes & fees 24 Jan - 25 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/37000000/36350000/36342700/36342606/d5bd0f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/37000000/36350000/36342700/36342606/b8d5dcb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/37000000/36350000/36342700/36342606/e1240ff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/37000000/36350000/36342700/36342606/e7617ff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott St. Louis Brentwood [](https://www.expedia.co.uk/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-Brentwood.h36342606.Hotel-Information) Richmond Heights 9.4/10 Exceptional (848 reviews) "We always enjoy our stay here nice clean and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dominique £100 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-Brentwood.h36342606.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/1d22ac52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/68b7c425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/15695a25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Queen Accessible Roll In Shower, Non Smoking | Blackout curtains, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/7c7fdb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Charles St. Peters [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information) St. Charles 8.0/10 Very good (1,006 reviews) "Great location and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather £77 includes taxes & fees 5 Feb - 6 Feb [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/69d580ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/199cb80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/e5c2fe9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/3b98f0e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel St. Louis Chesterfield [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) Chesterfield 9.6/10 Exceptional (1,051 reviews) "Absolutely amazing stay very nice play our family stays there every time very kid friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew £112 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/254f5b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/ad6cce96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/0b058bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, St. Charles Historic District [](https://www.expedia.co.uk/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) St. Charles Historic District 9.4/10 Exceptional (1,006 reviews) "We had a great stay in a beautiful area. The staff were friendly, and Kay at the front desk was so kind and welcoming!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Audrey £96 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/w2897h2195x0y8-cdf51e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/996a216e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/1004381f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/150f8d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonrise Hotel [](https://www.expedia.co.uk/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) Delmar Loop 9.0/10 Wonderful (1,925 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward £116 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/460000/459100/459083/38c972e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/460000/459100/459083/7456ba66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/460000/459100/459083/454352f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/460000/459100/459083/f1d7472f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casino Queen Hotel [](https://www.expedia.co.uk/St-Louis-Hotels-Casino-Queen-Hotel.h459083.Hotel-Information) East St. Louis 7.6/10 Good (1,987 reviews) "Yes it was a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suzy £73 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Casino-Queen-Hotel.h459083.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-26&endDate=2026-01-27®ionId=7051&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSt-Ann-Hotels.d7051.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSt-Ann-Hotels.d7051.Travel-Guide-Hotels) ## Top St. Ann Hotel Reviews ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg) ### Ameristar Casino Resort and Spa 10/10 Excellent "Everything was beautiful from the hotel staff to the room. It was great." [](https://expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "Great except for the breakfast. Eggs were rubbery, bone in the sausage, orange was dry." [](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 10/10 Excellent "Wonderful stay" [](https://expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg) ### 21C Museum Hotel St Louis 10/10 Excellent "Good vibe" [](https://expedia.co.uk/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg) ### The Wildwood Hotel 10/10 Excellent "We enjoyed our stay! Close to skiing and tubing. Lots of restaurants close. Kids loves the small swimming pool" [](https://expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg) ### Pear Tree Inn St. Louis Airport 10/10 Excellent "Staff and clean" [](https://expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![DoubleTree by Hilton St. Louis Forest Park](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/3f93ad2e_y.jpg) ### DoubleTree by Hilton St. Louis Forest Park 10/10 Excellent "Hdhsjs" [](https://expedia.co.uk/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) ![Hampton Inn St. Louis-Downtown (At the Gateway Arch)](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/w3837h2560x0y0-a6354f1b_y.jpg) ### Hampton Inn St. Louis-Downtown (At the Gateway Arch) 10/10 Excellent "Awesome location to the Gateway National Arch, Economy Museum, and dome. Loved the friendly staff! The building was very secure and safe feeling with my family in the city. The breakfast area is very well kept and kept stocked well. " [](https://expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Gateway-Arch-Downtown.h22520.Hotel-Information) ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd_y.jpg) ### Clayton Plaza Hotel & Extended Stay 10/10 Excellent "The room was very cozy and welcoming. The staff was great and friendly from checking in to the breakfast host to checking out." [](https://expedia.co.uk/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ## More cheap stays in St. Ann ![Relax Inn Saint Charles ](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/3d3bc786_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Relax Inn Saint Charles 3800 Harry S Truman Blvd St. Charles MO £52 18 Jan - 19 Jan includes taxes & fees 6.6/10 (999 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information) ![Motel 6 Hazelwood, MO](https://images.trvl-media.com/lodging/1000000/10000/500/457/82f143a9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Hazelwood, MO 5781 Campus Ct Hazelwood MO £55 1 Feb - 2 Feb includes taxes & fees 8.4/10 Very Good! (1,664 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Motel-6-Hazelwood.h457.Hotel-Information) ![Americas Best Value Inn & Suites St. Louis, St. Charles Inn](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/c17520b0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Americas Best Value Inn & Suites St. Louis, St. Charles Inn 1310 Bass Pro Drive St. Charles MO £61 13 Jan - 14 Jan includes taxes & fees 5.6/10 (1,007 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Americas-Best-Value-Inn-Suites-St-Louis.h68132.Hotel-Information) ![Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave ](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/3904d866_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 5823 Wilson Avenue St. Louis MO £66 15 Jan - 16 Jan includes taxes & fees 5.8/10 (1,002 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Red-Roof-Inn-PLUS-St-Louis-Forest-Park-Hampton-Ave.h24411.Hotel-Information) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn St. Louis Airport 10810 Pear Tree Ln St. Ann MO £79 16 Jan - 17 Jan includes taxes & fees 9.2/10 Wonderful! (2,762 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Hampton Inn St. Louis-Downtown (At the Gateway Arch)](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/w3837h2560x0y0-a6354f1b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn St. Louis-Downtown (At the Gateway Arch) 333 Washington Ave St. Louis MO £85 18 Jan - 19 Jan includes taxes & fees 8.6/10 Excellent! (1,210 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Gateway-Arch-Downtown.h22520.Hotel-Information) ## Frequently asked questions ### Where is the best place for a stay in St. Ann? ### What are some of the best holiday rentals that St. Ann has to offer? ### If I need to cancel my hotel reservation in St. Ann, will I receive a refund? ### What's the best accommodation for a budget-friendly stay in St. Ann? ### What's the best family accommodation in St. Ann? ### What is the top LGBTQ-friendly place to stay in St. Ann? ### What's the best dog-friendly accommodation option in St. Ann? ### What are some accommodation options with pools in St. Ann? ### How is it to stay in St. Ann? ### What should I see while I'm in St. Ann? ### What's the seasonal weather like in St. Ann? ## Explore a world of travel with Expedia - Accommodation - Flights - Cars - More ways to book - [Berkeley Hotels ](https://www.expedia.co.uk/Berkeley-St-Louis-Hotels.0-n6272-0.Travel-Guide-Filter-Hotels) - 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