Title: Top-Rated Hotels in St. Ann, Missouri 2026 | Expedia.co.uk [Holiday Rentals in St. Ann](https://expedia.co.uk/St-Ann-Holiday-Rentals.d7051.Travel-Guide-HolidayRentals)[St. Ann Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-St-Ann.d7051.Car-Hire-Guide)[St. Ann Holidays](https://expedia.co.uk/St-Ann.d7051.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in St. Ann Spa [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=SPA_ON_SITE) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=APARTMENT) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=HOT_TUB) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&amenities=PETS) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=CONDO) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Ann%2C+Missouri%2C+United+States+of+America®ionId=7051&latLong=38.730938%2C-90.388962&adults=2&startDate=2026-03-12&d1=2026-03-12&endDate=2026-03-14&d2=2026-03-14&lodging=COTTAGE) ## Check prices for these dates Tonight [26 Feb - 27 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=7051&startDate=2026-02-26&endDate=2026-02-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Feb - 28 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=7051&startDate=2026-02-27&endDate=2026-02-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=7051&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=7051&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for St. Ann hotels ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Desk, blackout curtains, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/30c70db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/68c9f9ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/4d0e3d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Airport [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) St. Ann 9.4/10 Exceptional (2,829 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandy £78 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/e043dfbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/4f4ebed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/8337bebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/370f73f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham St. Louis Airport [](https://www.expedia.co.uk/St-Louis-Hotels-Wingate-By-Wyndham-St-Louis-Airport.h18172.Hotel-Information) St. Ann 9.2/10 Wonderful (1,529 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra £89 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Wingate-By-Wyndham-St-Louis-Airport.h18172.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted bathtub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/66ab3de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/9fbd251c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wildwood Hotel [](https://www.expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) Wildwood 9.2/10 Wonderful (1,622 reviews) "Clean room and great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawn £76 includes taxes & fees 17 Mar - 18 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/415/b788e069.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/10000/500/415/24576741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/500/415/a17b50b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/500/415/6e3c31b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western St. Louis-Kirkwood Route 66 [](https://www.expedia.co.uk/St-Louis-Hotels-Best-Western-Kirkwood-Inn.h415.Hotel-Information) Kirkwood 8.4/10 Very good (1,412 reviews) "Room, breakfast and location are all good. We stayed here three days for hidden valley ski, I don't regret the choice:)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Xiongyu £77 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Best-Western-Kirkwood-Inn.h415.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/07ad5898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/b11945d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/9c480f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3870000/3861200/3861101/ccd5355f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Arnold [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Arnold.h3861101.Hotel-Information) Arnold 9.6/10 Exceptional (1,000 reviews) "Everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rilyn £107 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Arnold.h3861101.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/79d56802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/7f62e770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/25e461ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/7efb516b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel St. Louis St. Charles [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information) St. Charles 9.6/10 Exceptional (1,001 reviews) "Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John Christopher £113 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/220000/215200/215149/345278af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/220000/215200/215149/58454332.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/220000/215200/215149/f64cb47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/215200/215149/aad2ff4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta Simply Suites St Louis Earth City [](https://www.expedia.co.uk/St-Louis-Hotels-Sonesta-Simply-Suites-St-Louis-Earth-Cty.h215149.Hotel-Information) Earth City 8.8/10 Excellent (839 reviews) "The rooms were spotless and the staff was great would definitley recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trish £79 includes taxes & fees 18 Mar - 19 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Sonesta-Simply-Suites-St-Louis-Earth-Cty.h215149.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/26900/26898/05d3d451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26900/26898/5a02998b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26900/26898/1f50c457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/26900/26898/2fb0ddf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn St Louis SW - Route 66 by IHG [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-St-Louis-SW-Route-66.h26898.Hotel-Information) St. Louis 9.0/10 Wonderful (433 reviews) "Clean hotel and lots to do." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Paige £103 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-St-Louis-SW-Route-66.h26898.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/d33a8d98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/64e96650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/26078d49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/5c9c1d9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Arnold [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Arnold.h40112.Hotel-Information) Arnold 9.4/10 Exceptional (1,001 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin £77 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Arnold.h40112.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/70b128db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/4519749c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/d825c5c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/w2880h1936x0y0-34b8c827.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ameristar Casino Resort and Spa [](https://www.expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) St. Charles 8.4/10 Very good (1,001 reviews) "The room was great. I enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wanda £160 includes taxes & fees 9 Mar - 10 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/540000/531400/531329/18dd5677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/540000/531400/531329/3dd1ec30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/540000/531400/531329/67b22cca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/540000/531400/531329/f62d518a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Parkway Hotel [](https://www.expedia.co.uk/Collinsville-Hotels-Best-Western-Plus-Parkway-Hotel.h531329.Hotel-Information) Alton 8.2/10 Very good (1,002 reviews) "Nice room, good location. Helpful staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimra £70 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Collinsville-Hotels-Best-Western-Plus-Parkway-Hotel.h531329.Hotel-Information) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/07f8c63c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/5cdbca92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/c98607b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/f94e59bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites O'Fallon MO - Technology Drive [](https://www.expedia.co.uk/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information) O'Fallon 9.0/10 Wonderful (1,000 reviews) "Friendly staff, clean room, comfy bed, excellent breakfast buffet." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy £69 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/254f5b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/0036679a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/ad6cce96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, St. Charles Historic District [](https://www.expedia.co.uk/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) St. Charles Historic District 9.4/10 Exceptional (1,002 reviews) "Wonderful place staff awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chad £97 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/3e0ca2c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/b0c1520e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/dbfe312f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1210000/1206500/1206489/c06ddb8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express St. Louis West - O'Fallon by IHG [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-West-OFallon.h1206489.Hotel-Information) O'Fallon 8.6/10 Excellent (873 reviews) "Service, cleanliness and breakfast were all very agreeable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £76 includes taxes & fees 12 Mar - 13 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-West-OFallon.h1206489.Hotel-Information) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/550000/546400/546395/e29c4bca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/550000/546400/546395/9f625b0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/550000/546400/546395/1bfa886b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/550000/546400/546395/9bd5c64a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham St Louis Route 66 [](https://www.expedia.co.uk/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-St-Louis-Route-66.h546395.Hotel-Information) St. Louis 8.2/10 Very good (1,012 reviews) "Great location for getting past the city and close to interstate " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) barbara £89 includes taxes & fees 4 Mar - 5 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-St-Louis-Route-66.h546395.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/69d580ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/3b98f0e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/199cb80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/fee9b391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel St. Louis Chesterfield [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) Chesterfield 9.6/10 Exceptional (1,078 reviews) "The staff was super nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy £111 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/68bc6d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/0c7d61f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/c689fe3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/cf4e5d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis St. Peters [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-St-Peters.h41453.Hotel-Information) St. Peters 9.4/10 Exceptional (1,001 reviews) "Comfortable room. Quiet even though next to interstate. Excellent food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Geo £93 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-St-Peters.h41453.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/027f4cb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/0dec5b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/27bb4b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/45f37dd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn St. Louis - Creve Coeur by IHG [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-St-Louis-Creve-Coeur.h38967650.Hotel-Information) St. Louis 8.8/10 Excellent (362 reviews) "Very nice employees." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £88 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-St-Louis-Creve-Coeur.h38967650.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/a81cbeae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/95983c36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 23 per person)](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/a4621b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/879431a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance St. Louis Airport Hotel [](https://www.expedia.co.uk/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) Berkeley 8.4/10 Very good (1,069 reviews) "Everything was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JOHN £110 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/6093d918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/b493e570.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/897465ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/159a98ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites St Charles - St Louis [](https://www.expedia.co.uk/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information) St. Charles 8.4/10 Very good (1,006 reviews) "Great hotel for the money" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jere £78 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-12&endDate=2026-03-13®ionId=7051&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_SPRING_PROMO_7051) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSt-Ann-Hotels.d7051.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSt-Ann-Hotels.d7051.Travel-Guide-Hotels) ## Top St. Ann Hotel Reviews ![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/78b2a688_y.jpg) ### Drury Plaza Hotel St. Louis at the Arch 10/10 Excellent "The staff was very courteous! Amazing accommodations and a perfect experience." [](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton 10/10 Excellent "Wonderful hotel and staff" [](https://expedia.co.uk/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 10/10 Excellent "Great service, and the room was perfect." [](https://expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "The room appeared nice and clean! We ended up getting a suite…..for our particular purposes in a difficult season of life, it was a God ordained gift in every way! 🙏 Just what we needed for our 3 night stay! Thank you for your great service and good breakfasts! " [](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg) ### Pear Tree Inn St. Louis Airport 10/10 Excellent "Quick check-in, clean room, very friendly staff" [](https://expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Wingate by Wyndham St. Louis Airport](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/f94bc4e7_y.jpg) ### Wingate by Wyndham St. Louis Airport 10/10 Excellent "Clean room and the location " [](https://expedia.co.uk/St-Louis-Hotels-Wingate-By-Wyndham-St-Louis-Airport.h18172.Hotel-Information) ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg) ### The Wildwood Hotel 10/10 Excellent "Everything was great" [](https://expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Drury Inn & Suites St. Louis Union Station](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4_y.jpg) ### Drury Inn & Suites St. Louis Union Station 10/10 Excellent "All staff were so friendly!" [](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Courtyard by Marriott St. Louis Downtown/Convention Center](https://images.trvl-media.com/lodging/1000000/850000/848500/848402/b44eefea_y.jpg) ### Courtyard by Marriott St. Louis Downtown/Convention Center 10/10 Excellent "All of the staff were super friendly." [](https://expedia.co.uk/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-DowntownConvention-Center.h848402.Hotel-Information) ## More cheap stays in St. Ann ![Relax Inn Saint Charles ](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/3d3bc786_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Relax Inn Saint Charles 3800 Harry S Truman Blvd St. Charles MO £52 1 Mar - 2 Mar includes taxes & fees 6.8/10 (1,001 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information) ![Motel 6 Hazelwood, MO](https://images.trvl-media.com/lodging/1000000/10000/500/457/82f143a9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Hazelwood, MO 5781 Campus Ct Hazelwood MO £54 12 Mar - 13 Mar includes taxes & fees 8.4/10 Very Good! (1,792 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Motel-6-Hazelwood.h457.Hotel-Information) ![Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave ](https://images.trvl-media.com/lodging/1000000/30000/24500/24411/3904d866_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 5823 Wilson Avenue St. Louis MO £70 2 Mar - 3 Mar includes taxes & fees 5.8/10 (1,003 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Red-Roof-Inn-PLUS-St-Louis-Forest-Park-Hampton-Ave.h24411.Hotel-Information) ![Americas Best Value Inn & Suites St. Louis, St. Charles Inn](https://images.trvl-media.com/lodging/1000000/70000/68200/68132/c17520b0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Americas Best Value Inn & Suites St. Louis, St. Charles Inn 1310 Bass Pro Drive St. Charles MO £77 2 Mar - 3 Mar includes taxes & fees 5.8/10 (1,009 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Americas-Best-Value-Inn-Suites-St-Louis.h68132.Hotel-Information) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn St. Louis Airport 10810 Pear Tree Ln St. Ann MO £78 5 Mar - 6 Mar includes taxes & fees 9.4/10 Exceptional! (2,829 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Hampton Inn St. Louis-Downtown (At the Gateway Arch)](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/w3837h2560x0y0-a6354f1b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn St. Louis-Downtown (At the Gateway Arch) 333 Washington Ave St. Louis MO £92 8 Mar - 9 Mar includes taxes & fees 8.8/10 Excellent! (1,230 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Gateway-Arch-Downtown.h22520.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in St Ann? > This area is primarily commercial, featuring a good selection of hotels, restaurants, and shops clustered around the major road networks. It's a practical choice for travellers who value convenience and easy navigation, especially if arriving by car or needing quick access to the wider St. Louis metropolitan area. You'll find most services you need within a short drive. > > > For solo travellers or business visitors, staying near this intersection is particularly suitable. The hotels in this vicinity often provide amenities like complimentary breakfast, high-speed internet, and sometimes even high-end fitness equipment, suiting those who appreciate efficiency and comfort during their stay. ### What are the best hotels in St Ann that travellers recommend? > The Pear Tree Inn St. Louis Airport has an outstanding 9.4 rating. Guests frequently praise the friendly and helpful staff, the comfortable and clean rooms, and the great breakfast. Its convenient location and free, easy parking are also highly valued by visitors. Free airport transportation is provided, along with off-street and accessible parking options. > > > Another highly recommended option is the Wingate by Wyndham St. Louis Airport, which has a 9.2 rating. This hotel is commended for its friendly and helpful staff, comfortable and clean rooms, and great breakfast. It offers a 24-hour airport shuttle, free airport transportation, and complimentary self-parking. ### What are the best family hotels in St Ann? > The Wingate by Wyndham St. Louis Airport, with an impressive 9.2 rating, offers a variety of amenities great for families, including sofa beds, complimentary cribs, and connecting rooms. Guests frequently praise the friendly and helpful staff, comfortable and clean rooms, and the great breakfast. The hotel also provides free WiFi, complimentary airport transportation, and free self-parking for added convenience. > > > Another highly-rated option is the Pear Tree Inn St. Louis Airport, which boasts a 9.4 rating. This hotel provides free cribs for families, complimentary breakfast and buffet breakfast, as well as free self-parking. Guests often highlight the friendly and helpful staff, comfortable and clean rooms, and the great breakfast. Free WiFi and complimentary airport transportation are also provided. ### What hotels in St Ann offer free breakfast? > The Pear Tree Inn St. Louis Airport, with an outstanding 9.4 rating, provides a free buffet breakfast daily. Guests frequently highlight the friendly and helpful staff, comfortable and clean rooms, and the convenient location. It also offers free Wi-Fi, free self-parking, and complimentary airport transportation. > > > Another excellent option is the Wingate by Wyndham St. Louis Airport, rated 9.2\. This hotel offers a free continental breakfast daily, along with free Wi-Fi, free self-parking, and a 24-hour airport shuttle. Travellers often praise the friendly staff, comfortable rooms, and the great breakfast. Both hotels are conveniently located near the Blacks in Flight Mural. ### What are the top pet-friendly hotels in St Ann? > The Pear Tree Inn St. Louis Airport, with a 9.4 rating, warmly welcomes both dogs and cats. Guests frequently praise the friendly and helpful staff, comfortable and clean rooms, and the great complimentary buffet breakfast. Its convenient location and free, easy parking are also highly valued by travellers. > > > Another excellent choice is the Wingate by Wyndham St. Louis Airport, rated 9.2\. This hotel also permits both dogs and cats and offers a range of convenient amenities, including free WiFi, complimentary toiletries, and a free crib upon request. For those travelling by air, a 24-hour free airport shuttle and free self-parking are provided. Guests consistently highlight the friendly and helpful staff, comfortable rooms, and great complimentary continental breakfast. ### What are the best budget hotels in St Ann? > The Wingate by Wyndham St. Louis Airport, with a 9.2 rating, offers comfortable and clean rooms along with a complimentary continental breakfast. Guests appreciate the free airport transportation, available 24 hours, and the convenience of free WiFi and self-parking. The hotel is also located just 0.6 km from the Blacks in Flight Mural. > > > Another highly-rated option is the Pear Tree Inn St. Louis Airport, which has an impressive 9.4 rating. This hotel provides a complimentary buffet breakfast, free WiFi, and free self-parking. Like the Wingate, it also offers free airport transportation and is conveniently located 0.6 km from the Blacks in Flight Mural. ### What hotels are near St. Louis, MO (STL-Lambert-St. Louis Intl.)? > This highly-rated hotel, with a 9.4 review score, is exceptionally convenient as it is located just 0.6 km from St. Louis, MO (STL-Lambert-St. Louis Intl.). Guests frequently praise the friendly and helpful staff, as well as the comfortable and clean rooms. The hotel offers a complimentary buffet breakfast and free Wi-Fi, along with free airport transportation, making it ideal for travellers. Free self-parking is also available, which guests find easy and convenient. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a St. Ann hotel booking with Expedia? ### How much is the nightly rate at a St. Ann hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Cars - More ways to book - [Berkeley Hotels ](https://www.expedia.co.uk/Berkeley-St-Louis-Hotels.0-n6272-0.Travel-Guide-Filter-Hotels) - [Bridgeton Hotels ](https://www.expedia.co.uk/Bridgeton-Hotels.d7043.Travel-Guide-Hotels) - [Castle Point Hotels ](https://www.expedia.co.uk/Castle-Point-Hotels.d6351830.Travel-Guide-Hotels) - [Clayton Hotels ](https://www.expedia.co.uk/Clayton-St-Louis-Hotels.0-n6058846-0.Travel-Guide-Filter-Hotels) - [Creve Coeur Hotels ](https://www.expedia.co.uk/Creve-Coeur-St-Louis-Hotels.0-n7717-0.Travel-Guide-Filter-Hotels) - [Downtown Clayton Hotels ](https://www.expedia.co.uk/Downtown-Clayton-St-Louis-Hotels.0-n553248635976477194-0.Travel-Guide-Filter-Hotels) - 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