
Southern Arizona Holidays from £745
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Your Southern Arizona Holiday
Set off on your next big adventure with a Southern Arizona holiday package, and leave knowing all the details are taken care of. And with the ability to customise your escape, you know it'll be one to remember! Begin your trip to Southern Arizona with a few nights in Tucson visiting popular sights like Tucson Mall and Pima Air and Space Museum. Yuma is another city that lures travellers from near and far. Lutes Casino and Yuma Territorial Prison State Historic Park are two of the leading places to see in this destination. Expedia has everything you need for organising your Southern Arizona holiday. From flights and hotels, to activities and more, we're here to help you curate a travel experience like no other.
Top Southern Arizona Flight + Hotel Deals

Westgate Painted Mountain Golf Resort
Reviewed on 27 Aug 2025

Hyatt Vacation Club at Pinon Pointe, Sedona
Reviewed on 27 Aug 2025

Arabella Hotel Sedona
Reviewed on 28 Aug 2025


Villas At Poco Diablo
Reviewed on 28 Aug 2025
Where to stay in Southern Arizona

Catalina Foothills
If you're spending some time in Catalina Foothills, St. Phillips Plaza and La Encantada are top sights worth seeing.
Southern Arizona Holiday Packages
Both the heart of the Old West and a secret home to the Cold War’s nuclear activity, this unique Arizonan area offers intriguing desert landscape.
Just north of the Mexican border, Southern Arizona is a region rich in human history. Inhabited since pre-Columbian times, the area has provided homes for Native American tribes, cowboys, miners and nuclear missile technicians in the last two centuries. Visit the region to discover its wealth of museums and galleries, historic towns and varied landscapes. From the cactus-studded deserts to the strange rock formations of the low-lying Chiricahua Mountains, Southern Arizona is an area of exceptional natural beauty.
Base your travels in Southern Arizona from TucsonOpens in a new window, the state’s second-largest city. Here find all the modern amenities of an international city alongside 35 historic precincts. Ride Tucson’s famous streetcar to discover the city’s major attractions, including St. Augustine CathedralOpens in a new window and the Tucson Museum of ArtOpens in a new window. Find both in Downtown TucsonOpens in a new window, alongside hip restaurants, fashionable bars and excellent shopping opportunities.
Take a daytrip from the city to explore the surrounding area. Drive 30 minutes south to reach the Titan Missile MuseumOpens in a new window, a fascinating relic of the Cold War era. Take a guided tour of the former nuclear missile site to see a 103-foot-long (30-metre) Titan II missile.
Located on two sites on either side of Tucson, Saguaro National ParkOpens in a new window is one of Southern Arizona’s most idyllic natural destinations. Named after an enormous cactus, the national park features plants that draw most visitors. Capture photographs of spectacular desert sunsets before returning to the city. While summer has extreme heat at the peak of the day, winter in the desert offers milder days.
Mining was once the major industry of Southern Arizona. Visit Bisbee to see its picturesque main street and remnants of the Old West. Take a trip down into the Copper Queen Mine.
Southern Arizona is served by the Tucson International Airport as well as bus and train services. Rent a car for the freedom to explore its natural landscapes. Find accommodation in Tucson and the smaller towns of the region.
Southern Arizona Essential Information
Language | English |
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Currency | U.S dollars |
Closest Airport | Sky Harbour Intl. Airport (PHX) |
Top hotels in Southern Arizona

3 Palms Tucson North Foothills
Reviewed on 25 Aug 2025

Hotel McCoy - Art, Coffee, Beer, Wine

La Quinta Inn & Suites by Wyndham Tucson Airport
Popular places to visit

Saguaro National Park
Hike, bike or drive through fields and forests containing one of the most recognized cactus plants in the world.

Pima Air and Space Museum
One of the largest aviation museums in the world houses aircraft and spacecraft from the 1920s to the present.

O.K. Corral
You can browse the exhibits at O.K. Corral, a museum with a story of its own, during your travels to Tombstone. Discover the area's desert landscape and seek out the horse riding.
What to do in Southern Arizona

Phoenix: Self-Drive ATV/UTV Rental in the Sonoran Desert

Spa-Quality On Demand Massage - Phoenix/Scottsdale
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.