Title: The Best Hotels Closest to South Texas Medical Center in San Antonio - 2026 Updated Prices | Expedia.co.uk [South Texas Medical Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Texas-Medical-Center.d6193120.Car-Hire-Guide)[South Texas Medical Center Holidays](https://expedia.co.uk/South-Texas-Medical-Center-Medical-Center-District.d6193120.Attraction) ![SanAntonio_SouthTexasMedicalCenter_6193120_01](https://images.trvl-media.com/place/6193120/6208bc73-d0ab-4fda-b1af-d2c1bae086ed.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6193120/6208bc73-d0ab-4fda-b1af-d2c1bae086ed.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [27 Mar - 28 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6193120&startDate=2026-03-27&endDate=2026-03-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6193120&startDate=2026-03-28&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6193120&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6193120&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for South Texas Medical Center hotels ![Lobby](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/1c416f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/0a8f490a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/52bae0c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, free cots/infant beds](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/0716970b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott San Antonio Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information) Medical Center District, 0.6 mi from South Texas Medical Center 9.0/10 Wonderful (1,001 reviews) "clean room staff was very friendly, breakfast was amazing!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Drew £86 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Antonio-Medical-Center.h68847371.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/1e7b2c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/2045bf85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/db09d138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, pay films](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/f47c7eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Medical Center San Antonio [](https://www.expedia.co.uk/San-Antonio-Hotels-Courtyard-By-Marriott-Medical-Center-San-Antonio.h12556.Hotel-Information) Medical Center District, 0.8 mi from South Texas Medical Center 8.8/10 Excellent (1,000 reviews) "Clean, helpful staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edna £87 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Courtyard-By-Marriott-Medical-Center-San-Antonio.h12556.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/86df295b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/8e301658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/0e1dc134.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/e4545fb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites San Antonio Northwest Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Drury-Inn-Suites-San-Antonio-Northwest-Medical-Center.h59226.Hotel-Information) Medical Center District, 1.8 mi from South Texas Medical Center 9.2/10 Wonderful (1,289 reviews) "Had a great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARY £80 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Drury-Inn-Suites-San-Antonio-Northwest-Medical-Center.h59226.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/3b4d6808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/d85458fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/ded9f09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW [](https://www.expedia.co.uk/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) Medical Center District, 1.5 mi from South Texas Medical Center 8.4/10 Very good (3,237 reviews) "Clean room, comfortable beds, awesome breakfast. The stay was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) VERNA £79 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/9628dbca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/4918a4df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/fea7afce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/ea511f30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson [](https://www.expedia.co.uk/San-Antonio-Hotels-Welcome-Inn-San-Antonio-Medical-Center.h28102.Hotel-Information) Medical Center District, 0.6 mi from South Texas Medical Center 7.2/10 Good (1,000 reviews) "Room was spotless and bed was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela £56 includes taxes & fees 15 Apr - 16 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Welcome-Inn-San-Antonio-Medical-Center.h28102.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/1b117ba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Deluxe Suite | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/3d551d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 Queen Deluxe Suites | Bathroom | Combined shower/bathtub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/d7b70ede.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/97000000/96190000/96182100/96182039/82bbe653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Atria Inn & Suites [](https://www.expedia.co.uk/San-Antonio-Hotels-9727-Fredericksburg-Rd.h96182039.Hotel-Information) Medical Center District, 1.4 mi from South Texas Medical Center 7.6/10 Good (284 reviews) "Yes .staff really nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jamar £39 includes taxes & fees 27 Apr - 28 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-9727-Fredericksburg-Rd.h96182039.Hotel-Information) ![Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/cfce1826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/0d622081.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/15001725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/84000000/83410000/83406000/83405963/e2843e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 San Antonio, Tx - Northwest Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Studio-6-San-Antonio.h83405963.Hotel-Information) Medical Center District, 1.7 mi from South Texas Medical Center 7.4/10 Good (262 reviews) "This Hotel is well lit and we felt safe. The staff was outstanding during check in and check out! Room was very clean. We had a very comfortable stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gilbert £39 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Studio-6-San-Antonio.h83405963.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/41551429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/e974d0cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/6d7e3cbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/700000/692600/692534/a061f3de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Inn & Suites Medical Center San Antonio [](https://www.expedia.co.uk/San-Antonio-Hotels-OYO-Inn-Suites-Medical-Center-San-Antonio.h692534.Hotel-Information) Medical Center District, 1.9 mi from South Texas Medical Center 7.2/10 Good (229 reviews) "Staff was courteous and professional and the room is nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £54 includes taxes & fees 10 Apr - 11 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-OYO-Inn-Suites-Medical-Center-San-Antonio.h692534.Hotel-Information) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/c7a8846b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/60308f28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/45eebc93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/10b53b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Extended Stay - San Antonio, TX - Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Studio-6-San-Antonio.h50914.Hotel-Information) Medical Center District, 0.8 mi from South Texas Medical Center 6.8/10 (847 reviews) "Good place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) fidel £39 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Studio-6-San-Antonio.h50914.Hotel-Information) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/63a40a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/ca8040db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/e79204bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/39b28cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, San Antonio Medical Center, TX [](https://www.expedia.co.uk/San-Antonio-Hotels-Country-Inn-Suites-By-Radisson.h11744297.Hotel-Information) Medical Center District, 1.6 mi from South Texas Medical Center 6.8/10 (1,002 reviews) "A good hotel choice. Had a good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelsey £53 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Country-Inn-Suites-By-Radisson.h11744297.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/1000000/20000/14200/14170/60f5286e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/14200/14170/4b7bbf8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/20000/14200/14170/1d33dc79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/14200/14170/4a569e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Antonio, TX - Fiesta Trails [](https://www.expedia.co.uk/San-Antonio-Hotels-Motel-6-San-Antonio.h14170.Hotel-Information) 1.8 mi from South Texas Medical Center 6.6/10 (990 reviews) "I like is a clean hotel. The a/c worked nocely." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juana £43 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Motel-6-San-Antonio.h14170.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/c1974da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/ff104fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/a8e3513c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50600/50555/a69289e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Antonio, TX - Northwest Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Motel-6-San-Antonio.h50555.Hotel-Information) Medical Center District, 1.7 mi from South Texas Medical Center 6.0/10 (999 reviews) "Room was clean, beds comfortable, staff extremely friendly and helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen £42 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Motel-6-San-Antonio.h50555.Hotel-Information) ![Basic Room, 1 King Bed, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/53fea236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room, Multiple Beds, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/42431698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/52d716c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/76000000/75220000/75211700/75211602/00bf65b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Flex Studios [](https://www.expedia.co.uk/San-Antonio-Hotels-Flex-Studios.h75211602.Hotel-Information) Medical Center District, 1.7 mi from South Texas Medical Center 6.0/10 (515 reviews) "It was a comfortable stay. No roaches or bed bugs at affordable prices " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) FrankR £37 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Flex-Studios.h75211602.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/aa83e7de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/004315aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/e0b99e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/243881ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Antonio Marriott Northwest Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-San-Antonio-Marriott-Northwest.h4192.Hotel-Information) Medical Center District, 2 mi from South Texas Medical Center 8.6/10 Excellent (1,004 reviews) "Perfect place to stay comfy and clean delicious food good staff thank you much." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iris Grisell £95 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-San-Antonio-Marriott-Northwest.h4192.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/ba68f6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/32f5e634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/c57c3f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/40500/40467/f6e7b585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott San Antonio Medical Center/NW [](https://www.expedia.co.uk/San-Antonio-Hotels-SpringHill-Suites-By-Marriott-San-Antonio-Medical-CenterNW.h40467.Hotel-Information) 2 mi from South Texas Medical Center 8.8/10 Excellent (1,000 reviews) "Room were nice clean and neat also bed are comfortable. It was close to hospital and many restaurants close by . Staff was very nice and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catalina £87 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-SpringHill-Suites-By-Marriott-San-Antonio-Medical-CenterNW.h40467.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/41800/41734/cb7f797a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch flat-screen TV with cable channels, TV, pay films](https://images.trvl-media.com/lodging/1000000/50000/41800/41734/f26b581c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch flat-screen TV with cable channels, TV, pay films](https://images.trvl-media.com/lodging/1000000/50000/41800/41734/94060d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/41800/41734/8cb01bdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place San Antonio-Northwest/Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Hyatt-Place-San-Antonio-NorthwestMedical-Center.h41734.Hotel-Information) 2.1 mi from South Texas Medical Center 8.4/10 Very good (1,002 reviews) "Our stay was very amazing! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariana £75 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Hyatt-Place-San-Antonio-NorthwestMedical-Center.h41734.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/40800/40748/7a3cf3bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40748/a5f8996e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/50000/40800/40748/950b6923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40748/2a521daf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton San Antonio Northwest [](https://www.expedia.co.uk/San-Antonio-Hotels-Homewood-Suites-By-Hilton-San-Antonio-Northwest.h40748.Hotel-Information) 2 mi from South Texas Medical Center 8.4/10 Very good (1,000 reviews) "Good location, cleanliness was just ok, especially the bathroom. Breakfast was mediocre. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £101 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Homewood-Suites-By-Hilton-San-Antonio-Northwest.h40748.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/340000/330600/330588/e9167f57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/1000000/340000/330600/330588/185e087f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/340000/330600/330588/90cf9a46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/340000/330600/330588/bb8de4fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta ES Suites San Antonio Northwest - Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Sonesta-ES-Suites-San-Antonio-Northwest.h330588.Hotel-Information) 2 mi from South Texas Medical Center 8.2/10 Very good (1,003 reviews) "Best place to stay with family " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia £64 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Sonesta-ES-Suites-San-Antonio-Northwest.h330588.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723234/cb2e2e16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723234/8bdbdcb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723234/950bbe90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723234/c7d4fb16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott San Antonio Northwest [](https://www.expedia.co.uk/San-Antonio-Hotels-TownePlace-Suites-By-Marriott-San-Antonio-Northwest.h1723234.Hotel-Information) 2.3 mi from South Texas Medical Center 8.2/10 Very good (1,001 reviews) "Always a pleasure to visit this hotel when I come to visit family" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Svetlana £76 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-TownePlace-Suites-By-Marriott-San-Antonio-Northwest.h1723234.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2600000/2595600/2595553/ebbc7a98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2600000/2595600/2595553/c6564ec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2600000/2595600/2595553/f7bffcb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2600000/2595600/2595553/6fffa329.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites San Antonio Northwest/Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Hampton-Inn-Suites-San-Antonio-NorthwestMedical-Center.h2595553.Hotel-Information) Northwest Side, 2.6 mi from South Texas Medical Center 8.4/10 Very good (1,078 reviews) "Everything was pleasant and clean and breakfast was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tommy C. £62 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Hampton-Inn-Suites-San-Antonio-NorthwestMedical-Center.h2595553.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-10&endDate=2026-04-11®ionId=6193120&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to South Texas Medical Center | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Lobby](https://images.trvl-media.com/lodging/69000000/68850000/68847400/68847371/1c416f1a.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Fairfield Inn & Suites by Marriott San Antonio Medical Center | 3.0 star property | 9.0Wonderful1,001 reviews | View | | | | | | | ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12600/12556/1e7b2c4d.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Courtyard by Marriott Medical Center San Antonio | 3.0 star property | 8.8Excellent1,000 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/86df295b.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Drury Inn & Suites San Antonio Northwest Medical Center | 3.0 star property | 9.2Wonderful1,289 reviews | View | | | | | | | ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/3b4d6808.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW | 3.0 star property | 8.4Very good3,237 reviews | View | | | | | | | ![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/28200/28102/9628dbca.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Park Inn by Radisson | 2.0 star property | 7.2Good1,000 reviews | View | | | | | | ## Top South Texas Medical Center Hotel Reviews ![San Antonio Marriott Northwest Medical Center](https://images.trvl-media.com/lodging/1000000/10000/4200/4192/aa83e7de_y.jpg) ### San Antonio Marriott Northwest Medical Center 10/10 Excellent "Bar was out of some items pools was clean and nice" [](https://expedia.co.uk/San-Antonio-Hotels-San-Antonio-Marriott-Northwest.h4192.Hotel-Information) ![Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a5ac356f_y.jpg) ### Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG 10/10 Excellent "Spacious room for my family of 4 which included a 2 year old and 7 year old. Room was nice and cold, we had no issues. They even let us check out an hour later to give my family a little more time. Recommend!" [](https://expedia.co.uk/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information) ![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/3b4d6808_y.jpg) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW 10/10 Excellent "We've stayed here several times over the past 10 years and it's a very good hotel for the price. Clean rooms, well kept bathroom, adequate breakfast. It's in a good location close to the medical center. We will keep it as our primary choice in the area " [](https://expedia.co.uk/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) ![Drury Inn & Suites San Antonio Northwest Medical Center](https://images.trvl-media.com/lodging/1000000/60000/59300/59226/86df295b_y.jpg) ### Drury Inn & Suites San Antonio Northwest Medical Center 10/10 Excellent "Our stay at the Drury was fantastic. Starting with Lisa at the front desk. She was so friendly and helpful. She explained the parking, finding our room, snd all details of happy hour and breakfast. The staff for the HHsnd breakfast were also very friendly and attentive. The room was spotless and very comfortable. We are so happy to finally find a hotel of this quality and so affordable." [](https://expedia.co.uk/San-Antonio-Hotels-Drury-Inn-Suites-San-Antonio-Northwest-Medical-Center.h59226.Hotel-Information) ![The Westin San Antonio North](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6_y.jpg) ### The Westin San Antonio North 6/10 Okay "Very very old , not too clean . The bedding had a strong strong scent of bleach I guess that’s ok to ensure they are clean but not very appealing. The Rio was extremely dark no good lighting at all. Very inconvenient that you had to use your room key for the elevator to work. Give 2 out of 5 stars would not stay again for that price ." [](https://expedia.co.uk/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information) ![Sonesta ES Suites San Antonio Northwest - Medical Center](https://images.trvl-media.com/lodging/1000000/340000/330600/330588/e9167f57_y.jpg) ### Sonesta ES Suites San Antonio Northwest - Medical Center 10/10 Excellent "Terrible place to stay. Our carpet was filthy. There was a terrible smell of sewer. Our shower had mold and hair on the drain. When I sat on the chair there were screws poking out from it. Will never stay here again." [](https://expedia.co.uk/San-Antonio-Hotels-Sonesta-ES-Suites-San-Antonio-Northwest.h330588.Hotel-Information) ![Hyatt Place San Antonio-Northwest/Medical Center](https://images.trvl-media.com/lodging/1000000/50000/41800/41734/cb7f797a_y.jpg) ### Hyatt Place San Antonio-Northwest/Medical Center 8/10 Good "Breakfast menu was ok. The omelette was cold. " [](https://expedia.co.uk/San-Antonio-Hotels-Hyatt-Place-San-Antonio-NorthwestMedical-Center.h41734.Hotel-Information) ![Studio 6 San Antonio, TX - Medical Center](https://images.trvl-media.com/lodging/1000000/60000/51000/50914/c7a8846b_y.jpg) ### Studio 6 San Antonio, TX - Medical Center 8/10 Good "Very good location , clean rooms" [](https://expedia.co.uk/San-Antonio-Hotels-Studio-6-San-Antonio.h50914.Hotel-Information) ![Country Inn & Suites by Radisson, San Antonio Medical Center, TX](https://images.trvl-media.com/lodging/12000000/11750000/11744300/11744297/63a40a4f_y.jpg) ### Country Inn & Suites by Radisson, San Antonio Medical Center, TX 2/10 Terrible "I had never stayed here before and I never will again. The room had filthy carpet, there was mold in the shower stall and there was hair on the drain. There was a hole in the bathroom wall over the door that was patched with toilet paper. When we got back from dinner there was a terrible sewer smell in the lobby and it smelled just as bad in our room on the second floor. We tried calling the front desk from the phone in our room and from the cell phone and no one ever answered. By this time it was almost 11 and we were too tired to try to find another place to go. The outside was littered with soft drink bottles and paper. I don’t recommend this place at all. " [](https://expedia.co.uk/San-Antonio-Hotels-Country-Inn-Suites-By-Radisson.h11744297.Hotel-Information) ## Hotels near other South Texas Medical Center attractions ### Cinemark San Antonio 16 You can take time to visit Cinemark San Antonio 16 during your travels to San Antonio. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941654161276207104) ### USAA Corporate Office Headquarters USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621593511346) ### First Unitarian Universalist Church First Unitarian Universalist Church is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Amble around this family-friendly area's riverfront or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532643654) ### Wonderland of the Americas Mall You can enjoy retail therapy at Wonderland of the Americas Mall during your trip to San Antonio. Stroll along the riverfront in this family-friendly area or seek out the cycling trails. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6127197) ### Dellview Park After visiting Dellview Park, make a plan to see the other sights and activities in San Antonio. Amble around this family-friendly area's riverfront or experience its great live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6229159) ### Regal Huebner Oaks You can take time to visit Regal Huebner Oaks during your travels to San Antonio. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941653986642092032) ### Huebner Oaks You can find the perfect gifts to bring home at Huebner Oaks during your stay in San Antonio. Discover the great live music in this romantic area or seek out the cycling trails. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6230811) ### Crystal Ice Palace Catch an event at Crystal Ice Palace and enjoy other activities in San Antonio such as cycling.Amble around this family-friendly area's riverfront or experience its great live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532643385) ## Frequently asked questions ### What's the area like around South Texas Medical Center? ### What's the best hotel to stay close to South Texas Medical Center? ### How many hotels should I expect to find close to South Texas Medical Center? ### If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund? ### What can I see and do near South Texas Medical Center?