Title: TOP Hotels near Museums in South San Diego, CA for 2025 | Expedia.co.uk [South San Diego Travel Guide](https://expedia.co.uk/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.co.uk/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Holiday Rentals in South San Diego](https://expedia.co.uk/South-San-Diego-Holiday-Rentals.d553248632063518562.Travel-Guide-HolidayRentals)[Flights to South San Diego](https://expedia.co.uk/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.co.uk/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-San-Diego.d553248632063518562.Car-Hire-Guide)[South San Diego Holidays](https://expedia.co.uk/South-San-Diego.d553248632063518562.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/1577a5f9f9b33dbc18377fc367dd66b8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels near Museums in South San Diego ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South San Diego Hotels near Museums Tonight [16 Oct - 17 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-10-16&endDate=2025-10-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [17 Oct - 18 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-10-17&endDate=2025-10-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South San Diego Hotels near Museums ![Smart TV, video games, books, music library](https://images.trvl-media.com/lodging/120000000/119570000/119567700/119567642/65b4f5d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/120000000/119570000/119567700/119567642/39df1a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, video games, books, music library](https://images.trvl-media.com/lodging/120000000/119570000/119567700/119567642/e03cc39f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/120000000/119570000/119567700/119567642/6788954b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious-Gate-Ranch-KingBed-1600 sqft 3Beds/1.5Bth Spring Valley £240 includes taxes & fees 22 Oct - 23 Oct [](https://www.expedia.co.uk/Spring-Valley-Hotels-Spacious-Gate-Ranch.h119567642.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-31&endDate=2025-11-01®ionId=553248632063518562&adults=2&location_highlights_explore=museums&sort=RECOMMENDED&openPlayBack=true) ## Top South San Diego Hotel Reviews ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Great" [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![The Sofia Hotel](//images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Excellent downtown location. Convenient to The convention center, little Italy and many restaurants. " [](https://expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Best Western Inn & Suites San Diego – Zoo/SeaWorld Area ](//images.trvl-media.com/lodging/1000000/50000/40800/40745/a5f33771_y.jpg) ### Best Western Inn & Suites San Diego – Zoo/SeaWorld Area 10/10 Excellent "Check in very easy, excellent customer service " [](https://expedia.co.uk/San-Diego-Hotels-Comfort-Inn-Suites-San-Diego-Zoo-SeaWorld-Area.h40745.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Great Service " [](https://expedia.co.uk/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![San Diego Marriott La Jolla](//images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Clean and friendly" [](https://expedia.co.uk/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Clean room, Staff Friendly" [](https://expedia.co.uk/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Clean room polite staff" [](https://expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Clean rooms, nice staff etc.." [](https://expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Staff was super friendly, room and propert was clean. Great experience!" 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[Flights to San Ysidro](https://www.expedia.co.uk/Cheap-Flights-To-San-Ysidro.d8380.Travel-Guide-Flights) - [Flights from San Ysidro](https://www.expedia.co.uk/lp/flights/8380/flights-from-san-ysidro) - [Visit Otay](https://www.expedia.co.uk/Chula-Vista-Otay.dx177685) - [Chula Vista Holidays](https://www.expedia.co.uk/Chula-Vista.d7442.Holidays-City-Breaks) - [Visit Chula Vista](https://www.expedia.co.uk/Chula-Vista.dx7442) - [Visit Ocean View Hills](https://www.expedia.co.uk/San-Diego-Ocean-View-Hills.dx553248635976008220) - [Visit Otay Mesa West](https://www.expedia.co.uk/San-Diego-Otay-Mesa-West.dx553248625809641010) - [Visit San Ysidro](https://www.expedia.co.uk/San-Ysidro.dx8380) - [Car hire Chula Vista](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Chula-Vista.d7442.Car-Hire-Guide) - [Car hire San Ysidro](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Ysidro.d8380.Car-Hire-Guide) - [Chula Vista Holiday Rentals](https://www.expedia.co.uk/Chula-Vista-Holiday-Rentals.d7442.Travel-Guide-HolidayRentals) - [Things to do in Chula Vista](https://www.expedia.co.uk/Things-To-Do-In-Chula-Vista.d7442.Travel-Guide-Activities)