Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured South of Market Independent Hotels

See all 658 Hotels in South of Market
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.1 out of 5 (3,187 reviews)
Fantastic historic property with a Grand lobby Fantastic historic property with Grand Lobby filled with marble, massive wood details and massive d … - 

£140

£140
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,814 reviews)
A short stat in San Fran CBD Well located across from union square, excellent facilities including fitness centre, quiet rooms a … - 

£164

£164
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,612 reviews)
Nice hotel! This place was absolutely beautiful on the inside and out. We were informed however that they are r … - 

£175

£175
Hotel Zoe San Francisco

Hotel Zoe San Francisco

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,358 reviews)
holiday lovely stay here. Place spotless, doors opened for you, nothing too much trouble. Staff lovely.Ate … - 

£186

£186
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,268 reviews)
ambiance good We're happy even it was a short stay, we get to lounge outside the hotel comfortably, less noise, c … - 

£168

£168
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.0 out of 5.0
4.5 out of 5 (2,129 reviews)
Everyhing was nice. Only issue was with the internet connection. - 

£103

£103
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,753 reviews)
Excellent service great location near everything Will stay again. - 

£153

£153
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,054 reviews)
Very nice hotel, clean room and friendly staff. The hotel is very nice and clean. Staff is helpful and friendly. Several restaurants on the propert … - 

£321

£321
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (879 reviews)
The Zephyr is a nice hotel in a central location Booked though Expedia and had a trouble-free experience for 5 nights in a two-bed nice room on 2nd … - 

£180

£180
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,912 reviews)
Good hotel close to the wharf. Breakfast was excellent - 

£234

£234
Map

Recently booked South of Market hotels

Civic Center Motor Inn
2.0 out of 5.0
Last booking: 1 hour ago
Hotel Whitcomb
3.5 out of 5.0
Last booking: 3 hours ago
Americas Best Value Inn & Suites SoMa
2.0 out of 5.0
Last booking: 3 hours ago
Best Western Plus Americania
3.0 out of 5.0
Last booking: 3 hours ago
W San Francisco
4.0 out of 5.0
Last booking: 4 hours ago
Four Seasons Hotel San Francisco
5.0 out of 5.0
Last booking: 4 hours ago
InterContinental San Francisco
4.5 out of 5.0
Last booking: 4 hours ago
Desmond Hotel
2.5 out of 5.0
Last booking: 4 hours ago
Hampton Inn San Francisco Downtown/Convention Center
3.0 out of 5.0
Last booking: 5 hours ago

Pocket Guide: Independent Hotels in South of Market

Search for hotels in South of Market on Expedia. You can easily find your hotels in South of Market using one of the methods below:

  • View our selection of featured hotels in South of Market
  • Use the map to find hotels in the South of Market neighborhood you prefer
  • Use the filters to see hotels in a specific area of South of Market, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in South of Market
  • Enter your travel dates to view the best deals on hotels in South of Market - while they last