Santiago Este Holidays from £526
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top Santiago Este Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá
San Francisco
£631
per person
22 Dec - 26 Dec
found 11 hours ago
Return flight included
Georgetown (GEO) to Panama City (PTY)
8.4/10 Very good! (1,693 reviews)
loved my family suite !!! very spacious and cute ! awesome views… the pool was such a vibe even on the days it did rain the bar was still open. great location in the city
Reviewed on 27 Sept 2026
Top hotels in Santiago Este
Hotel Mykonos Panama
Panamerican Highway Nuevo Santiago Veraguas
Fully refundableReserve now, pay when you stay
£69
5 Oct - 6 Oct
includes taxes & fees
Hotel Gran David
Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
£64
29 Sept - 30 Sept
includes taxes & fees
HOTEL VISTA LAGO
Rincón Largo La Pena Santiago de Veraguas
Fully refundableReserve now, pay when you stay
£64
29 Sept - 30 Sept
includes taxes & fees
9.4/10 Exceptional! (126 reviews)
"Todo perfecto"
Reviewed on 19 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
