Title: The Best Hotels Closest to Santa Fe Depot Museum in Gainesville - 2026 Updated Prices | Expedia.co.uk [Gainesville Travel Guide](https://expedia.co.uk/Gainesville.dx6058890)[Holiday Rentals in Gainesville](https://expedia.co.uk/Gainesville-Holiday-Rentals.d6058890.Travel-Guide-HolidayRentals)[Santa Fe Depot Museum Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe-Depot-Museum.d6218928.Car-Hire-Guide)[Santa Fe Depot Museum Holidays](https://expedia.co.uk/Santa-Fe-Depot-Museum-Gainesville.d6218928.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [7 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6218928&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [8 Feb - 9 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6218928&startDate=2026-02-08&endDate=2026-02-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6218928&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6218928&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Santa Fe Depot Museum hotels ![Seasonal outdoor pool, open 7:00 AM to 11:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/41000000/40210000/40201500/40201485/c7f7cef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/41000000/40210000/40201500/40201485/2855f760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/41000000/40210000/40201500/40201485/7d4e506a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/41000000/40210000/40201500/40201485/2a2a3939.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lancaster Manor B&B [](https://www.expedia.co.uk/Gainesville-Hotels-The-Lancaster-Manor-Bed-And-Breakfast.h40201485.Hotel-Information) 0.5 mi from Santa Fe Depot Museum 10/10 Exceptional (92 reviews) "I wish I could give 10 stars. Every thing there was top of the line. Host treat you like family, full service bed and breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MICHAEL £165 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-The-Lancaster-Manor-Bed-And-Breakfast.h40201485.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/37000000/36970000/36969900/36969803/755bceca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/37000000/36970000/36969900/36969803/2efb6ba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/37000000/36970000/36969900/36969803/2dbb1d08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/37000000/36970000/36969900/36969803/3da59b17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Gainesville I-35 [](https://www.expedia.co.uk/Gainesville-Hotels-Fairfield-Inn-Suites-By-Marriott-Gainesville-I-35.h36969803.Hotel-Information) 1.1 mi from Santa Fe Depot Museum 8.8/10 Excellent (1,003 reviews) "We loved staying here. The room was very clean - and the staff was super welcoming and friendly. 10/10 recommend!!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maryelle £74 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Gainesville-Hotels-Fairfield-Inn-Suites-By-Marriott-Gainesville-I-35.h36969803.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/920000/914500/914425/6c14726b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/920000/914500/914425/04cf4410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/920000/914500/914425/69672f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/920000/914500/914425/1a648eb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Gainesville by IHG [](https://www.expedia.co.uk/Gainesville-Hotels-Holiday-Inn-Express-Hotel-Suites-Gainesville.h914425.Hotel-Information) 0.7 mi from Santa Fe Depot Museum 7.8/10 Good (1,004 reviews) "Excellent room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £72 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Holiday-Inn-Express-Hotel-Suites-Gainesville.h914425.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/16400/16393/64da6a9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16400/16393/d2893b5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16400/16393/902faa90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/16400/16393/00acce81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Days-Inn-By-Wyndham-Gainesville.h16393.Hotel-Information) 1.5 mi from Santa Fe Depot Museum 7.6/10 Good (1,002 reviews) "Clean room staff friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jim £55 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Gainesville-Hotels-Days-Inn-By-Wyndham-Gainesville.h16393.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/930000/922300/922204/45302e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/930000/922300/922204/b7eb2045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/930000/922300/922204/6560adf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/930000/922300/922204/a550def9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Gainesville TX [](https://www.expedia.co.uk/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville-TX.h922204.Hotel-Information) 1.7 mi from Santa Fe Depot Museum 7.2/10 Good (1,012 reviews) "Great place for the money " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lesmar £52 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Super-8-By-Wyndham-Gainesville-TX.h922204.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1650000/1641200/1641171/69064f0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1650000/1641200/1641171/305faba9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1650000/1641200/1641171/03597c39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1650000/1641200/1641171/bfe693ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Comfort-Suites-Gainesville.h1641171.Hotel-Information) 1.6 mi from Santa Fe Depot Museum 6.6/10 (1,008 reviews) "Everything about this place was awesome! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £57 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Gainesville-Hotels-Comfort-Suites-Gainesville.h1641171.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1130000/1123900/1123885/9c332979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1130000/1123900/1123885/d6f99afe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1130000/1123900/1123885/84c52fc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/2000000/1130000/1123900/1123885/497dd7ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Host Motel Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Budget-Host-Motel-Gainesville.h1123885.Hotel-Information) 1.7 mi from Santa Fe Depot Museum 6.6/10 (503 reviews) "Nice quiet clean place for the price cant beat it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawn £46 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Budget-Host-Motel-Gainesville.h1123885.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/14100/14044/ae26153d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/20000/14100/14044/66658fb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14100/14044/b60f8e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14100/14044/82be8e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Quality-Inn-Gainesville.h14044.Hotel-Information) 0.5 mi from Santa Fe Depot Museum 6.0/10 (1,002 reviews) "Rooms were good, service was excellent, all and all a good experience." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martin Rodriguez £45 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Quality-Inn-Gainesville.h14044.Hotel-Information) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101050000/101045200/101045112/cc6b7c22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101050000/101045200/101045112/3460efb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101050000/101045200/101045112/9bb79e1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101050000/101045200/101045112/0bbda746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suburban Studios Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Suburban-Studios-Gainesville.h101045112.Hotel-Information) 0.6 mi from Santa Fe Depot Museum 6.0/10 (194 reviews) "Good place to stay Many options in the area too eat" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £32 includes taxes & fees 9 Mar - 10 Mar [](https://www.expedia.co.uk/Gainesville-Hotels-Suburban-Studios-Gainesville.h101045112.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23000/22901/a5c5e05f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/23000/22901/w1507h1200x0y3-7e9aa5eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/30000/23000/22901/w1512h1196x0y2-e37fa87f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23000/22901/b94b677f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loyalty Inn Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Loyalty-Inn-Gainesville.h22901.Hotel-Information) 1.8 mi from Santa Fe Depot Museum 5.6/10 (684 reviews) "Staff is great and room was clean . " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Veronica £40 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Gainesville-Hotels-Loyalty-Inn-Gainesville.h22901.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/51000000/50920000/50916200/50916118/5a47ad26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/51000000/50920000/50916200/50916118/bdc1f314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/51000000/50920000/50916200/50916118/09cd4d65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/51000000/50920000/50916200/50916118/6d0937f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-Hampton-Inn-Suites-Gainesville.h50916118.Hotel-Information) 4 mi from Santa Fe Depot Museum 8.6/10 Excellent (1,008 reviews) "Nice place to stay clean rooms and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy £68 includes taxes & fees 9 Mar - 10 Mar [](https://www.expedia.co.uk/Gainesville-Hotels-Hampton-Inn-Suites-Gainesville.h50916118.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1760000/1753000/1752905/aa02f5b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1760000/1753000/1752905/31d36eb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Premium bedding, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1760000/1753000/1752905/1d005d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1760000/1753000/1752905/9ec5d632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Gainesville.h1752905.Hotel-Information) 4.2 mi from Santa Fe Depot Museum 8.0/10 Very good (1,000 reviews) "3rd time we have stayed here Great service, great staff… that is the reason we always come back.." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) louie and cinda £73 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/Gainesville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Gainesville.h1752905.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1620000/1618700/1618601/c8df272f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1620000/1618700/1618601/1dee01c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1620000/1618700/1618601/a6434de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1620000/1618700/1618601/e70c22bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lindsay Inn [](https://www.expedia.co.uk/Gainesville-Hotels-Lindsay-Inn.h1618601.Hotel-Information) 4.9 mi from Santa Fe Depot Museum 8.2/10 Very good (780 reviews) "Staff was great and the room was clean and very comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kerry £48 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-Lindsay-Inn.h1618601.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227691/0c57eed6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227691/d7b92d7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, Internet](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227691/w3837h2556x3y4-97e1e957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227691/w3836h2556x4y4-b0f5ef72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Red River Inn & Suites [](https://www.expedia.co.uk/Ardmore-Hotels-Best-Western-Red-River-Inn-Suites.h2227691.Hotel-Information) 8.6 mi from Santa Fe Depot Museum 9.0/10 Wonderful (1,033 reviews) "The staff there was wonderful" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) GERMAN £79 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Ardmore-Hotels-Best-Western-Red-River-Inn-Suites.h2227691.Hotel-Information) ![20-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/74000000/73360000/73356200/73356106/ea7c84b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/74000000/73360000/73356200/73356106/2698724f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/74000000/73360000/73356200/73356106/a19bdaec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/74000000/73360000/73356200/73356106/37f92c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Towering Oaks Event & Retreat Center [](https://www.expedia.co.uk/Valley-View-Hotels-Towering-Oaks-Event-Retreat-Center.h73356106.Hotel-Information) 9.6 mi from Santa Fe Depot Museum 9.8/10 Exceptional (33 reviews) "The accommodations and amenities were great. Mike and his mother were professional & accommodating and made us feel welcome. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Delana £128 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Valley-View-Hotels-Towering-Oaks-Event-Retreat-Center.h73356106.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5800000/5797900/5797801/d21d446e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5800000/5797900/5797801/e335c7f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/6000000/5800000/5797900/5797801/440dad7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5800000/5797900/5797801/05e5203a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red River Inn And Suites [](https://www.expedia.co.uk/Ardmore-Hotels-Red-River-Inn-And-Suites.h5797801.Hotel-Information) 8.6 mi from Santa Fe Depot Museum 7.4/10 Good (1,129 reviews) "room was clean staff super friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Petrox £93 includes taxes & fees 11 Mar - 12 Mar [](https://www.expedia.co.uk/Ardmore-Hotels-Red-River-Inn-And-Suites.h5797801.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2310000/2304700/2304673/a2d9663a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2310000/2304700/2304673/3cffda28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2310000/2304700/2304673/c98cb1ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2310000/2304700/2304673/10a2a877.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hotel Valley View TX, I-35 [](https://www.expedia.co.uk/Gainesville-Hotels-OYO-Hotel-Valley-View-TX-US-77.h2304673.Hotel-Information) 10.2 mi from Santa Fe Depot Museum 8.0/10 Very good (505 reviews) "The hotel was conveniently located to a venue we were attending a wedding and seeing friends. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patty £64 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Gainesville-Hotels-OYO-Hotel-Valley-View-TX-US-77.h2304673.Hotel-Information) ![Gift shop](https://images.trvl-media.com/lodging/123000000/122230000/122222100/122222090/567b038b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Gainesville [](https://www.expedia.co.uk/Gainesville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Gainesville.h122222090.Hotel-Information) 3.5 mi from Santa Fe Depot Museum [](https://www.expedia.co.uk/Gainesville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Gainesville.h122222090.Hotel-Information) ![Tranquility | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119380000/119373900/119373859/74312efe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/120000000/119380000/119373900/119373859/e806fca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools](https://images.trvl-media.com/lodging/120000000/119380000/119373900/119373859/bd78e292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s play area – outdoor](https://images.trvl-media.com/lodging/120000000/119380000/119373900/119373859/4985fa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oak Meadow Ranch [](https://www.expedia.co.uk/Valley-View-Hotels-Oak-Meadow-Ranch.h119373859.Hotel-Information) 9.3 mi from Santa Fe Depot Museum £178 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Valley-View-Hotels-Oak-Meadow-Ranch.h119373859.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-22&endDate=2026-02-23®ionId=6218928&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Santa Fe Depot Museum | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Seasonal outdoor pool, open 7:00 AM to 11:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/41000000/40210000/40201500/40201485/c7f7cef7.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)The Lancaster Manor B&B | 3.5 star property | 10.0Exceptional92 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/37000000/36970000/36969900/36969803/755bceca.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Fairfield Inn & Suites by Marriott Gainesville I-35 | 2.5 star property | 8.8Excellent1,003 reviews | View | | | | | | | ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/920000/914500/914425/6c14726b.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express Hotel & Suites Gainesville by IHG | 2.5 star property | 7.8Good1,004 reviews | View | | | | | | | ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/16400/16393/64da6a9e.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Days Inn by Wyndham Gainesville | 2.5 star property | 7.6Good1,002 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/1000000/930000/922300/922204/45302e01.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Super 8 by Wyndham Gainesville TX | 2.0 star property | 7.2Good1,012 reviews | View | | | | | | ## Top Santa Fe Depot Museum Hotel Reviews ![The Lancaster Manor B&B](https://images.trvl-media.com/lodging/41000000/40210000/40201500/40201485/4b2ea04c_y.jpg) ### The Lancaster Manor B&B 10/10 Excellent "Clean room, Great Brownies, Great Biscuits, Great Banana Nut bread. Loved the breakfast and Connie and John were so welcoming. Reserve the Rose room as it is the best room in the house. " [](https://expedia.co.uk/Gainesville-Hotels-The-Lancaster-Manor-Bed-And-Breakfast.h40201485.Hotel-Information) ![Best Western Red River Inn & Suites](https://images.trvl-media.com/lodging/3000000/2230000/2227700/2227691/93ace492_y.jpg) ### Best Western Red River Inn & Suites 10/10 Excellent "Rooms clean n smelled good.rest room cleaned well stocked.. " [](https://expedia.co.uk/Ardmore-Hotels-Best-Western-Red-River-Inn-Suites.h2227691.Hotel-Information) ![Red River Inn And Suites](https://images.trvl-media.com/lodging/6000000/5800000/5797900/5797801/28674795_y.jpg) ### Red River Inn And Suites 10/10 Excellent "Clean rooms " [](https://expedia.co.uk/Ardmore-Hotels-Red-River-Inn-And-Suites.h5797801.Hotel-Information) ![Suburban Studios Gainesville](https://images.trvl-media.com/lodging/102000000/101050000/101045200/101045112/9bb79e1e_y.jpg) ### Suburban Studios Gainesville 10/10 Excellent "Room was clean " [](https://expedia.co.uk/Gainesville-Hotels-Suburban-Studios-Gainesville.h101045112.Hotel-Information) ![Lindsay Inn](https://images.trvl-media.com/lodging/2000000/1620000/1618700/1618601/c8df272f_y.jpg) ### Lindsay Inn 10/10 Excellent "Nice clean comfortable room. Easy check-in and out. A little out of the way but in a good way. Quiet and comfortable. " [](https://expedia.co.uk/Gainesville-Hotels-Lindsay-Inn.h1618601.Hotel-Information) ![Loyalty Inn Gainesville](https://images.trvl-media.com/lodging/1000000/30000/23000/22901/a5c5e05f_y.jpg) ### Loyalty Inn Gainesville 10/10 Excellent "Staff is great and room was clean . " [](https://expedia.co.uk/Gainesville-Hotels-Loyalty-Inn-Gainesville.h22901.Hotel-Information) ![OYO Hotel Valley View TX, I-35](https://images.trvl-media.com/lodging/3000000/2310000/2304700/2304673/33d2ea6c_y.jpg) ### OYO Hotel Valley View TX, I-35 10/10 Excellent "The hotel was conveniently located to a venue we were attending a wedding and seeing friends. " [](https://expedia.co.uk/Gainesville-Hotels-OYO-Hotel-Valley-View-TX-US-77.h2304673.Hotel-Information) ## Hotels near other Santa Fe Depot Museum attractions ### Cooke County Courthouse 3.8/5 (15 reviews) After visiting Cooke County Courthouse, make a plan to see the other sights and activities in Gainesville. While you're in the area, find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6277689) ### Depot Park Depot Park is just one of the places to see in Gainesville, so why not enjoy the other things to explore during your travels? While in this family-friendly area, find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=875845101669322752) ### Butterfield Stage Players 3.5/5 (15 reviews) You can enjoy a show at Butterfield Stage Players during your stay in Gainesville. While you're in the area, find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6218908) ### State Theater 4.2/5 (5 reviews) You can enjoy a show at State Theater during your stay in Gainesville. While you're in the area, find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6218931) ### Morton Museum 3.5/5 (11 reviews) You can spend time studying the exhibits at Morton Museum during your trip to Gainesville. While you're in the area, find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6218925) ### Tom Thumb Park After visiting Tom Thumb Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=875846429822967808) ### Jaycee Park After visiting Jaycee Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=875843927299858432) ### Gainesville War Memorial 4.0/5 (25 reviews) Find out about the history of Gainesville with a stop at Gainesville War Memorial. While you're in the area, find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6218935) ## Frequently asked questions ### What's the area like around Santa Fe Depot Museum? ### What's the best place to stay near Santa Fe Depot Museum? ### How many hotels are there near Santa Fe Depot Museum? ### If I need to cancel the hotel reservation for my stay near Santa Fe Depot Museum, will I receive a refund? ### What can I see and do near Santa Fe Depot Museum?