Title: The Best Hotels Closest to San Sebastiano in Milan - 2026 Updated Prices | Expedia.co.uk

[Milan Centre Travel Guide](https://expedia.co.uk/Milan-Milan-Centre.dx6049534)[San Sebastiano Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Sebastiano.d553248621532507514.Car-Hire-Guide)[San Sebastiano Holidays](https://expedia.co.uk/San-Sebastiano-Milan-Centre.d553248621532507514.Attraction)

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## Check prices for these dates

Tonight

[12 Feb - 13 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532507514&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[13 Feb - 14 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532507514&startDate=2026-02-13&endDate=2026-02-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532507514&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532507514&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Property class

## Our top choices for San Sebastiano hotels

![Front of property](https://images.trvl-media.com/lodging/118000000/117770000/117760200/117760105/4876fdc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Balcony | Private kitchen | Fridge, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/118000000/117770000/117760200/117760105/9b0dea48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Balcony | Living area](https://images.trvl-media.com/lodging/118000000/117770000/117760200/117760105/2770dff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Balcony | Desk, free WiFi](https://images.trvl-media.com/lodging/118000000/117770000/117760200/117760105/78641a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Oriana Homèl Milano

[](https://www.expedia.co.uk/Milan-Hotels-Oriana-Homel-Milano.h117760105.Hotel-Information)

Centro Storico, < 0.1 mi from San Sebastiano

10/10

Exceptional

(48 reviews)

"Perfect stay!"

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Martin

£142

includes taxes & fees

15 Feb - 16 Feb

[](https://www.expedia.co.uk/Milan-Hotels-Oriana-Homel-Milano.h117760105.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19600/19524/a4783d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double or Twin Room, Non Smoking | Hypo-allergenic bedding, down duvets, free minibar items, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/19600/19524/7894c6cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast buffet](https://images.trvl-media.com/lodging/1000000/20000/19600/19524/9962a4ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double or Twin Room, Non Smoking | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/19600/19524/eeffd72f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Spadari Al Duomo

[](https://www.expedia.co.uk/Milan-Hotels-Hotel-Spadari-Al-Duomo.h19524.Hotel-Information)

Centro Storico, 0.1 mi from San Sebastiano

9.8/10

Exceptional

(650 reviews)

"Excelente place to stay everything is walkable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ramon

£366

includes taxes & fees

2 Mar - 3 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Hotel-Spadari-Al-Duomo.h19524.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/2000000/1080000/1074600/1074523/fb754da7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/2000000/1080000/1074600/1074523/725bace7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room, Terrace | Premium bedding, free minibar, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1080000/1074600/1074523/ab993337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1080000/1074600/1074523/d73dcf2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Gran Duca Di York

[](https://www.expedia.co.uk/Milan-Hotels-Hotel-Gran-Duca-Di-York.h1074523.Hotel-Information)

Centro Storico, 0.1 mi from San Sebastiano

9.6/10

Exceptional

(555 reviews)

"Staff,Location and breakfast excellent. Old Italian house/Villa.Rooms with terrace very comfortable but not modern."

![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg)

Alon

£245

includes taxes & fees

1 Mar - 2 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Hotel-Gran-Duca-Di-York.h1074523.Hotel-Information)

![Standard Room | Premium bedding, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/122000000/121300000/121293400/121293332/e3850982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer](https://images.trvl-media.com/lodging/122000000/121300000/121293400/121293332/1a6190e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/122000000/121300000/121293400/121293332/416b483f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer](https://images.trvl-media.com/lodging/122000000/121300000/121293400/121293332/81589da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### MAZZINI SUITES

[](https://www.expedia.co.uk/Milan-Hotels-MAZZINI-SUITES.h121293332.Hotel-Information)

Centro Storico, 0.1 mi from San Sebastiano

8.4/10

Very good

(7 reviews)

"La habitación muy amplia, la ubicación inmejorable a escasos 200 metros de la Plaza Duomo, muy buenas conexiones de parada de taxi y metro y el personal muy atento, un acierto si quieres alojarte en el centro."

![Spain](https://a.travel-assets.com/egds/marks/flags/es.svg)

Ana Belen Aguilar

£177

includes taxes & fees

26 Feb - 27 Feb

[](https://www.expedia.co.uk/Milan-Hotels-MAZZINI-SUITES.h121293332.Hotel-Information)

![Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/105000000/104020000/104016200/104016142/5747c18e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free toiletries, hair dryer, slippers, bidet](https://images.trvl-media.com/lodging/105000000/104020000/104016200/104016142/c4f3a9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/105000000/104020000/104016200/104016142/726e4fef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![42-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/105000000/104020000/104016200/104016142/3da1f64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AF Duomo - Milano Luxury Suites

[](https://www.expedia.co.uk/Milan-Hotels-AF-Duomo.h104016142.Hotel-Information)

Centro Storico, 0.2 mi from San Sebastiano

9.8/10

Exceptional

(30 reviews)

"Amazing view!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

£485

includes taxes & fees

23 Feb - 24 Feb

[](https://www.expedia.co.uk/Milan-Hotels-AF-Duomo.h104016142.Hotel-Information)

![Deluxe Condo | 1 bedroom, individually decorated, individually furnished](https://images.trvl-media.com/lodging/97000000/96880000/96875400/96875355/21433780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lift](https://images.trvl-media.com/lodging/97000000/96880000/96875400/96875355/f4ae37dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/97000000/96880000/96875400/96875355/cbf1c58f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Condo | View from room](https://images.trvl-media.com/lodging/97000000/96880000/96875400/96875355/3e143edd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### notaMi - Cinque Vie Top Floor City Center

[](https://www.expedia.co.uk/Milan-Hotels-NotaMI-Cinque-Vie-Top-Floor-CityCentre.h96875355.Hotel-Information)

0.3 mi from San Sebastiano

9.8/10

Exceptional

(16 reviews)

"Had a lovely stay with my daughter, walking distance to everything!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Kristina

[](https://www.expedia.co.uk/Milan-Hotels-NotaMI-Cinque-Vie-Top-Floor-CityCentre.h96875355.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/4c03a9c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/951b1f31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double or Twin Room | 1 bedroom, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/6a52e6b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Buffet](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/cd7161ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Room Mate Collection Giulia, Milan

[](https://www.expedia.co.uk/Milan-Hotels-Room-Mate-Giulia.h13318091.Hotel-Information)

Centro Storico, 0.3 mi from San Sebastiano

9.6/10

Exceptional

(1,000 reviews)

"Staff were above and beyond!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth

£325

includes taxes & fees

5 Mar - 6 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Room-Mate-Giulia.h13318091.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/93f73a57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exclusive Double or Twin Room, Balcony, City View | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/7f1b44c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/910dd1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/bfb680b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Square Milano Duomo - Preferred Hotels & Resorts

[](https://www.expedia.co.uk/Milan-Hotels-The-Square-Milano-Duomo-Preferred-Hotels-Resorts.h9385755.Hotel-Information)

Centro Storico, 0.2 mi from San Sebastiano

9.2/10

Wonderful

(1,008 reviews)

"Great location. Room with balcony was a good size and spotlessly clean. Good selection of food for breakfast. All staff were extremely helpful and friendly"

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Deborah-Ann

£239

includes taxes & fees

2 Mar - 3 Mar

[](https://www.expedia.co.uk/Milan-Hotels-The-Square-Milano-Duomo-Preferred-Hotels-Resorts.h9385755.Hotel-Information)

![Lunch and dinner served, Argentinean cuisine](https://images.trvl-media.com/lodging/42000000/41500000/41495300/41495232/97ff99b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Double Room, Terrace | Terrace/patio](https://images.trvl-media.com/lodging/42000000/41500000/41495300/41495232/388046ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/42000000/41500000/41495300/41495232/668ff1c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room | Down duvets, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/42000000/41500000/41495300/41495232/b85d34ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Speronari Suites

[](https://www.expedia.co.uk/Milan-Hotels-Speronari-Suites.h41495232.Hotel-Information)

Centro Storico, 0.1 mi from San Sebastiano

9.4/10

Exceptional

(212 reviews)

"Great location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bruce

£287

includes taxes & fees

2 Mar - 3 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Speronari-Suites.h41495232.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/10000000/9110000/9107300/9107202/a047a76c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/10000000/9110000/9107300/9107202/0db8d39d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/10000000/9110000/9107300/9107202/16255a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/10000000/9110000/9107300/9107202/d200f2d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Santa Marta Suites

[](https://www.expedia.co.uk/Milan-Hotels-Santa-Marta-Suites.h9107202.Hotel-Information)

Centro Storico, 0.1 mi from San Sebastiano

9.4/10

Exceptional

(136 reviews)

"Amazing location, amazing staff! The hotel has 5 floors, each with a suite and a hotel style room. The top floor has a terrace with views of the city. We walked everywhere during our stay. The front desk staff was fantastic, as was the restaurant. Thank you so much for a great first trip to Milano!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brittany

[](https://www.expedia.co.uk/Milan-Hotels-Santa-Marta-Suites.h9107202.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/749558de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Studio, 1 Bedroom (Via dei Piatti 4) | Terrace/patio](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/a4cc8746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![43-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/35ef0a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/34c68267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Milan Retreats Duomo

[](https://www.expedia.co.uk/Milan-Hotels-Milan-Retreats-Duomo.h44236363.Hotel-Information)

Centro Storico, 0.1 mi from San Sebastiano

9.2/10

Wonderful

(718 reviews)

"Excellent Hotel, nice room, clean. There is a great breakfast /lunch place called Monti Lab directly across the hotel, excellent coffee and pastry and very friendly, "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yan

£164

includes taxes & fees

23 Feb - 24 Feb

[](https://www.expedia.co.uk/Milan-Hotels-Milan-Retreats-Duomo.h44236363.Hotel-Information)

![Deluxe Room, 1 King Bed | 1 bedroom, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/100000000/99640000/99638000/99637953/f6b2a78c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite | Living area | 30-inch TV with digital channels, heated floors](https://images.trvl-media.com/lodging/100000000/99640000/99638000/99637953/327b0fea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/100000000/99640000/99638000/99637953/ca3c21cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/100000000/99640000/99638000/99637953/ed8fd180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Brivio

[](https://www.expedia.co.uk/Milan-Hotels-Casa-Brivio.h99637953.Hotel-Information)

Centro Storico, 0.2 mi from San Sebastiano

9.6/10

Exceptional

(35 reviews)

"Memorable stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nabeel

£287

includes taxes & fees

1 Mar - 2 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Casa-Brivio.h99637953.Hotel-Information)

![Deluxe Double Room, Balcony, City View | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/7000000/6450000/6443200/6443123/98ea8480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Kitchenette | Living area | Flat-screen TV, first-run films](https://images.trvl-media.com/lodging/7000000/6450000/6443200/6443123/5836f8e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, 1 Double Bed, City View (Large) | Room amenity](https://images.trvl-media.com/lodging/7000000/6450000/6443200/6443123/bdc36d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, Kitchenette | Living area | Flat-screen TV, first-run films](https://images.trvl-media.com/lodging/7000000/6450000/6443200/6443123/c3da95ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury Suite Milano Duomo

[](https://www.expedia.co.uk/Milan-Hotels-Luxury-Suite-Milano-Duomo.h6443123.Hotel-Information)

Centro Storico, 0.2 mi from San Sebastiano

9.4/10

Exceptional

(234 reviews)

"Beds were very comfortable, location was awesome "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nadia

£254

includes taxes & fees

5 Mar - 6 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Luxury-Suite-Milano-Duomo.h6443123.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665804/0fe68448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665804/22328428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665804/b2416364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665804/3684db43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Touring Club Milan, A Radisson Collection Hotel

[](https://www.expedia.co.uk/Milan-Hotels-Radisson-Collection-Palazzo-Touring-Club.h64665804.Hotel-Information)

Centro Storico, 0.2 mi from San Sebastiano

9.4/10

Exceptional

(196 reviews)

"All our stay was great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rodrigo

£386

includes taxes & fees

2 Mar - 3 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Radisson-Collection-Palazzo-Touring-Club.h64665804.Hotel-Information)

![Exclusive Apartment, 2 Bedrooms, City View (Via Santa Maria Valle 1) | Terrace/patio](https://images.trvl-media.com/lodging/12000000/11580000/11570600/11570532/681008f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Royal Apartment, 3 Bedrooms, City View (Via Santa Maria Valle 7) | Premium bedding, down duvets, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/12000000/11580000/11570600/11570532/7344002a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11580000/11570600/11570532/7e46886d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, 3 Bedrooms (8 People - Via delle Asole 2) | View from room](https://images.trvl-media.com/lodging/12000000/11580000/11570600/11570532/e54ca520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Heart Milan Apartments - San Sepolcro Duomo

[](https://www.expedia.co.uk/Milan-Hotels-Heart-Milan-Apartments-Duomo.h11570532.Hotel-Information)

Centro Storico, < 0.1 mi from San Sebastiano

9.2/10

Wonderful

(517 reviews)

"Beautiful place, amazing location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andre

£170

includes taxes & fees

2 Mar - 3 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Heart-Milan-Apartments-Duomo.h11570532.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/43000000/42250000/42246100/42246071/w5755h3835x5y5-93f455a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/43000000/42250000/42246100/42246071/w5757h3835x0y5-eb981d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Down duvets, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/43000000/42250000/42246100/42246071/e840d46a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Studio Suite (Junior Queen/Two Twin Beds Suite) | Down duvets, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/43000000/42250000/42246100/42246071/efdfea6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Matilde Boutique Hotel, WorldHotels Elite

[](https://www.expedia.co.uk/Milan-Hotels-Matilde-Boutique-Hotel.h42246071.Hotel-Information)

Centro Storico, 0.1 mi from San Sebastiano

9.2/10

Wonderful

(149 reviews)

"staff is great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

eric

£432

includes taxes & fees

13 Feb - 14 Feb

[](https://www.expedia.co.uk/Milan-Hotels-Matilde-Boutique-Hotel.h42246071.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/49000000/48710000/48703800/48703782/0e038214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down duvets, memory-foam beds, free minibar](https://images.trvl-media.com/lodging/49000000/48710000/48703800/48703782/6999ab1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![48-inch flat-screen TV with cable channels](https://images.trvl-media.com/lodging/49000000/48710000/48703800/48703782/b4abee28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony](https://images.trvl-media.com/lodging/49000000/48710000/48703800/48703782/740b5894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ODSweet Duomo Milano Hotel

[](https://www.expedia.co.uk/Milan-Hotels-ODSweet-Duomo-Milano-Hotel.h48703782.Hotel-Information)

Centro Storico, 0.2 mi from San Sebastiano

9.2/10

Wonderful

(173 reviews)

"Great location with a nice rooftop. Great room and great staff. I recommend it. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

VICTOR

£310

includes taxes & fees

11 Mar - 12 Mar

[](https://www.expedia.co.uk/Milan-Hotels-ODSweet-Duomo-Milano-Hotel.h48703782.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/13000000/12540000/12539500/12539421/e99c31f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (EUR 9.9 per person)](https://images.trvl-media.com/lodging/13000000/12540000/12539500/12539421/a76f81d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, individually furnished](https://images.trvl-media.com/lodging/13000000/12540000/12539500/12539421/4d647b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/13000000/12540000/12539500/12539421/557385f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ostello Bello Milano Duomo

[](https://www.expedia.co.uk/Milan-Hotels-Ostello-Bello.h12539421.Hotel-Information)

0.3 mi from San Sebastiano

9.4/10

Exceptional

(256 reviews)

"Everything was perfect. Awesome location. Friendly staff, would definitely stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Youbi

£154

includes taxes & fees

15 Feb - 16 Feb

[](https://www.expedia.co.uk/Milan-Hotels-Ostello-Bello.h12539421.Hotel-Information)

![Design Double Room, 1 King Bed | Bathroom | Free toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/19000000/18430000/18420600/18420593/42c368d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18430000/18420600/18420593/b1e40d95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/19000000/18430000/18420600/18420593/2d4ef41d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/19000000/18430000/18420600/18420593/968a9d43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Street Milano Duomo | a Design Boutique Hotel

[](https://www.expedia.co.uk/Milan-Hotels-The-Street-Milano-Duomo-A-Design-Boutique-Hotel.h18420593.Hotel-Information)

Centro Storico, 0.4 mi from San Sebastiano

9.4/10

Exceptional

(315 reviews)

"Great location for all activities "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Line

£270

includes taxes & fees

2 Mar - 3 Mar

[](https://www.expedia.co.uk/Milan-Hotels-The-Street-Milano-Duomo-A-Design-Boutique-Hotel.h18420593.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/23000000/22610000/22607300/22607293/38b107cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/23000000/22610000/22607300/22607293/8f994a30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/23000000/22610000/22607300/22607293/50596b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/23000000/22610000/22607300/22607293/3aa3f9bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Brera Apartments in City Center

[](https://www.expedia.co.uk/Milan-Hotels-Brera-Apartments-In-Nerino.h22607293.Hotel-Information)

Centro Storico, 0.1 mi from San Sebastiano

9.2/10

Wonderful

(31 reviews)

"We really enjoyed our stay. It was in a great location with so many restaurants and shopping nearby along with historical sites."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Leann

£195

includes taxes & fees

3 Mar - 4 Mar

[](https://www.expedia.co.uk/Milan-Hotels-Brera-Apartments-In-Nerino.h22607293.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27&regionId=553248621532507514&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top San Sebastiano Hotel Reviews

![ibis Milano Centro](https://images.trvl-media.com/lodging/1000000/910000/905600/905544/476f9bbe_y.jpg)

### ibis Milano Centro

10/10 Excellent

"Clean room and friendly staff! The chocolate scones at the breakfast buffet were also delicious. Great stay!"

[](https://expedia.co.uk/Milan-Hotels-Ibis-Milano-Centro.h905544.Hotel-Information)

![Milan Retreats Duomo](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/a9bcddf2_y.jpg)

### Milan Retreats Duomo

10/10 Excellent

"The rooms were clean, very well located. Staff is friendly. The address mentioned is that of the main office not the actual apartment which is only a 6 minutes walk. Nonetheless, the apartment has a very good location. "

[](https://expedia.co.uk/Milan-Hotels-Milan-Retreats-Duomo.h44236363.Hotel-Information)

![Uptown Palace](https://images.trvl-media.com/lodging/5000000/4260000/4251500/4251429/1e6f0aee_y.jpg)

### Uptown Palace

10/10 Excellent

"Great staff, clean room, great amenities. 1 drawback: the freshener spray is too strong in the room"

[](https://expedia.co.uk/Milan-Hotels-Uptown-Palace.h4251429.Hotel-Information)

![The Square Milano Duomo - Preferred Hotels & Resorts](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/ed764b1e_y.jpg)

### The Square Milano Duomo - Preferred Hotels & Resorts

10/10 Excellent

"⭐️⭐️⭐️⭐️⭐️ The Square Milano Duomo Hotel is a fantastic place to stay in Milan. The rooms are spacious and very comfortable, with a great mattress that made for an excellent night’s sleep. The location is unbeatable—just a 5-minute walk to the Duomo and close to all the main attractions, great restaurants, and the fashion district. The reception staff was friendly and helpful, providing excellent service throughout our stay. Everything was convenient and well-organized. I would definitely stay here again. Highly recommended!"

[](https://expedia.co.uk/Milan-Hotels-The-Square-Milano-Duomo-Preferred-Hotels-Resorts.h9385755.Hotel-Information)

![Room Mate Collection Giulia, Milan](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/b60d5ff3_y.jpg)

### Room Mate Collection Giulia, Milan

10/10 Excellent

"Staff were above and beyond!"

[](https://expedia.co.uk/Milan-Hotels-Room-Mate-Giulia.h13318091.Hotel-Information)

![Hotel Brunelleschi](https://images.trvl-media.com/lodging/1000000/20000/14300/14220/d215030e_y.jpg)

### Hotel Brunelleschi

10/10 Excellent

"Location close to main areas. Big room with relaxation areas as well. Clean and great breakfast options. Restaurant in the hotel was great as well."

[](https://expedia.co.uk/Milan-Hotels-Hotel-Brunelleschi.h14220.Hotel-Information)

![The Corner Duomo Hotel](https://images.trvl-media.com/lodging/42000000/41960000/41955800/41955718/a39e68a9_y.jpg)

### The Corner Duomo Hotel

10/10 Excellent

"Everything was great and Great location "

[](https://expedia.co.uk/Milan-Hotels-The-Corner-Duomo-Milano.h41955718.Hotel-Information)

![QC room Milano Porta Romana](https://images.trvl-media.com/lodging/114000000/113330000/113326000/113325923/9a914f72_y.jpg)

### QC room Milano Porta Romana

10/10 Excellent

"Modern, unique hotel. Very clean and stylish. Nice rooms. Lovely staff. "

[](https://expedia.co.uk/Milan-Hotels-QC-Room-Milano.h113325923.Hotel-Information)

![Hotel Rio](https://images.trvl-media.com/lodging/18000000/17750000/17748900/17748884/c25bfe5f_y.jpg)

### Hotel Rio

10/10 Excellent

"Really enjoyed my mini-break at The Rio. Small, but perfectly formed! Nice warm, clean room with excellent shower & . Smashing breakfast. Staff nice & friendly - even got me some milk to take to bed! Look forward to returning! "

[](https://expedia.co.uk/Milan-Hotels-Hotel-Rio.h17748884.Hotel-Information)

## Hotels near other San Sebastiano attractions

### Biblioteca Ambrosiana

One of Europe’s first public libraries is home to Leonardo da Vinci’s Codex Atlanticus, which is housed alongside a huge book and art collection.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6077526)

### Via Torino

During your visit to Milan, you can browse for the perfect souvenirs at Via Torino. Make time to visit the area's stunning cathedral or simply enjoy its charming cafes. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6216999)

### Chiesa di San Sepolcro

Chiesa di San Sepolcro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Discover the area's acclaimed art galleries and stunning cathedral. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532507515)

### Chiesa di Sant'Alessandro in Zebedia

Chiesa di Sant'Alessandro in Zebedia is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's shops or stunning cathedral to your travel plans. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532506989)

### Chiesa Santa Maria Presso di San Satiro

Chiesa Santa Maria Presso di San Satiro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's stunning cathedral or shops to your travel plans. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6077542)

### Museo Mangini Bonomi

You can study the exhibits at Museo Mangini Bonomi, a museum with a storied past, during your holiday in Milan. Experience the area's fascinating museums and acclaimed art galleries. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532507512)

### Casa Ferrario

You can study the exhibits at Casa Ferrario, a museum with a storied past, during your trip to Milan. Discover the area's acclaimed art galleries and stunning cathedral. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532507506)

### Church of San Giorgio al Palazzo

Church of San Giorgio al Palazzo is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Discover the area's acclaimed art galleries and shops. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532506040)

## Frequently asked questions

### What's the area like around San Sebastiano?

### What's the best place to stay near San Sebastiano?

### How many hotels will I be able to find close to San Sebastiano?

### If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund?

### What can I see and do near San Sebastiano?

### How can I get to San Sebastiano?