Title: The Best Hotels Closest to San Sebastiano in Milan - 2026 Updated Prices | Expedia.co.uk [Milan Centre Travel Guide](https://expedia.co.uk/Milan-Milan-Centre.dx6049534)[San Sebastiano Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Sebastiano.d553248621532507514.Car-Hire-Guide)[San Sebastiano Holidays](https://expedia.co.uk/San-Sebastiano-Milan-Centre.d553248621532507514.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [1 Apr - 2 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532507514&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [2 Apr - 3 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532507514&startDate=2026-04-02&endDate=2026-04-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532507514&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532507514&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for San Sebastiano hotels ![Front of property](https://images.trvl-media.com/lodging/118000000/117770000/117760200/117760105/4876fdc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/118000000/117770000/117760200/117760105/63a31c67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Balcony | Desk, free WiFi](https://images.trvl-media.com/lodging/118000000/117770000/117760200/117760105/78641a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Balcony | Private kitchen | Fridge, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/118000000/117770000/117760200/117760105/9b0dea48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oriana Homèl Milano [](https://www.expedia.co.uk/Milan-Hotels-Oriana-Homel-Milano.h117760105.Hotel-Information) Centro Storico, < 0.1 mi from San Sebastiano 10/10 Exceptional (57 reviews) "Great room and staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenny £190 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Milan-Hotels-Oriana-Homel-Milano.h117760105.Hotel-Information) ![Superior Apartment, 3 Bedrooms, Balcony , Via Cannobio 12 | Balcony](https://images.trvl-media.com/lodging/111000000/110600000/110594000/110593982/e0f40339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment, 1 Queen Bed with Sofa Bed, Patio, Via dell'Unione 7 | Living area](https://images.trvl-media.com/lodging/111000000/110600000/110594000/110593982/e7d36c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Elite Apartment, 2 Bedrooms, Balcony (Piazza Erculea 5) | Living area](https://images.trvl-media.com/lodging/111000000/110600000/110594000/110593982/b01c059c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment, 1 Queen Bed with Sofa Bed, Patio, Via dell'Unione 7 | Living area](https://images.trvl-media.com/lodging/111000000/110600000/110594000/110593982/b96d5161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart Milan Apartments Duomo Missori [](https://www.expedia.co.uk/Milan-Hotels-Heart-Milan-Apartments-Duomo-Missori.h110593982.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 10/10 Exceptional (17 reviews) "Great stay! Looking for a place to stay during olympics that would be comfortable and not off the charts. This was it -- lots of space for two people - would work for 3 or 4\. Excellent location - 5 mins from Duomo. Lots of terrific restaurants in Missori and Duomo area. Heart Milan service was excellent! Grazie!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £224 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Milan-Hotels-Heart-Milan-Apartments-Duomo-Missori.h110593982.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19600/19524/a4783d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 1 King Bed, Terrace | Hypo-allergenic bedding, down duvets, free minibar items, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/19600/19524/a760e18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double or Twin Room, Non Smoking | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/19600/19524/eeffd72f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double or Twin Room, Non Smoking | Hypo-allergenic bedding, down duvets, free minibar items, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/19600/19524/7894c6cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Spadari Al Duomo [](https://www.expedia.co.uk/Milan-Hotels-Hotel-Spadari-Al-Duomo.h19524.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 9.8/10 Exceptional (655 reviews) "Excelente place to stay everything is walkable" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramon £304 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-Hotel-Spadari-Al-Duomo.h19524.Hotel-Information) ![Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/105000000/104020000/104016200/104016142/5747c18e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, slippers, bidet](https://images.trvl-media.com/lodging/105000000/104020000/104016200/104016142/c4f3a9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/105000000/104020000/104016200/104016142/3da1f64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily cooked-to-order breakfast ](https://images.trvl-media.com/lodging/105000000/104020000/104016200/104016142/abd671c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AF Duomo - Milano Luxury Suites [](https://www.expedia.co.uk/Milan-Hotels-AF-Duomo.h104016142.Hotel-Information) Centro Storico, 0.2 mi from San Sebastiano 10/10 Exceptional (32 reviews) "Amazing view!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura £446 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Milan-Hotels-AF-Duomo.h104016142.Hotel-Information) ![Deluxe Room, 1 King Bed | 1 bedroom, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/100000000/99640000/99638000/99637953/f6b2a78c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99640000/99638000/99637953/4c114ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99640000/99638000/99637953/ed8fd180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite | Living area | 30-inch TV with digital channels, heated floors](https://images.trvl-media.com/lodging/100000000/99640000/99638000/99637953/327b0fea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Brivio [](https://www.expedia.co.uk/Milan-Hotels-Casa-Brivio.h99637953.Hotel-Information) Centro Storico, 0.2 mi from San Sebastiano 9.6/10 Exceptional (37 reviews) "Memorable stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nabeel £204 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-Casa-Brivio.h99637953.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/4c03a9c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Penthouse | Terrace/patio](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/03fdb5f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double or Twin Room | 1 bedroom, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/6a52e6b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/14000000/13320000/13318100/13318091/cd7161ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Room Mate Collection Giulia, Milan [](https://www.expedia.co.uk/Milan-Hotels-Room-Mate-Giulia.h13318091.Hotel-Information) Centro Storico, 0.3 mi from San Sebastiano 9.6/10 Exceptional (1,000 reviews) "Great rooms, great location and great staff. " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Jana £327 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/Milan-Hotels-Room-Mate-Giulia.h13318091.Hotel-Information) ![Down duvets, minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/42000000/41500000/41495300/41495232/e4f1a32f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/42000000/41500000/41495300/41495232/7caf9135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/42000000/41500000/41495300/41495232/668ff1c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Double Room, Terrace | Terrace/patio](https://images.trvl-media.com/lodging/42000000/41500000/41495300/41495232/388046ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Speronari Suites [](https://www.expedia.co.uk/Milan-Hotels-Speronari-Suites.h41495232.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 9.4/10 Exceptional (215 reviews) "The staff were wonderful and very helpful, the hotel is lovely and the location is ideal. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Regina £305 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-Speronari-Suites.h41495232.Hotel-Information) ![Exclusive Apartment, 2 Bedrooms, City View (Via Santa Maria Valle 1) | Terrace/patio](https://images.trvl-media.com/lodging/12000000/11580000/11570600/11570532/681008f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment, 2 Bedrooms (Via Giardino 1) | Living area | 65-inch flat-screen TV with digital channels, Netflix](https://images.trvl-media.com/lodging/12000000/11580000/11570600/11570532/4f3cd155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Royal Apartment, 3 Bedrooms, City View (Via Santa Maria Valle 7) | Premium bedding, down duvets, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/12000000/11580000/11570600/11570532/7344002a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment, 3 Bedrooms (8 People - Via delle Asole 2) | View from room](https://images.trvl-media.com/lodging/12000000/11580000/11570600/11570532/e54ca520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart Milan Apartments - San Sepolcro Duomo [](https://www.expedia.co.uk/Milan-Hotels-Heart-Milan-Apartments-Duomo.h11570532.Hotel-Information) Centro Storico, < 0.1 mi from San Sebastiano 9.2/10 Wonderful (525 reviews) "Was very central to a lot of activities. The apartment was clean and spacious and the staff was super friendly and helpful. Great for families or groups of friends. Totally recommend. I would go there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £153 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-Heart-Milan-Apartments-Duomo.h11570532.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/10000000/9110000/9107300/9107202/a047a76c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/10000000/9110000/9107300/9107202/d200f2d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/10000000/9110000/9107300/9107202/0053b8ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/10000000/9110000/9107300/9107202/16255a43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santa Marta Suites [](https://www.expedia.co.uk/Milan-Hotels-Santa-Marta-Suites.h9107202.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 9.4/10 Exceptional (137 reviews) "The staff was beyond helpful. The room was a bit run-down, but it was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alivia J [](https://www.expedia.co.uk/Milan-Hotels-Santa-Marta-Suites.h9107202.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87480000/87478100/87478064/a62247ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (EUR 15 per person)](https://images.trvl-media.com/lodging/88000000/87480000/87478100/87478064/b9fb8896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87480000/87478100/87478064/50f8b772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87480000/87478100/87478064/26e063d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santa Marta Suites [](https://www.expedia.co.uk/Milan-Hotels-SANTA-MARTA-SUITES.h87478064.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 9.2/10 Wonderful (168 reviews) "Hotel was close to main attractions but down a somewhat desolate side street. Room was way too hot and staff had a hard time correcting the temperature.eventually got it well enough to fall asleep. Otherwise very clean and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura £190 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Milan-Hotels-SANTA-MARTA-SUITES.h87478064.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/93f73a57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Double or Twin Room, Balcony, City View | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/7f1b44c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet breakfast on weekdays (EUR 30 per person)](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/964793c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9390000/9385800/9385755/910dd1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Square Milano Duomo - Preferred Hotels & Resorts [](https://www.expedia.co.uk/Milan-Hotels-The-Square-Milano-Duomo-Preferred-Hotels-Resorts.h9385755.Hotel-Information) Centro Storico, 0.2 mi from San Sebastiano 9.2/10 Wonderful (1,001 reviews) "Fantastic in everything from breakfast to room to location." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Terry £229 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-The-Square-Milano-Duomo-Preferred-Hotels-Resorts.h9385755.Hotel-Information) ![Standard Room | Premium bedding, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/122000000/121300000/121293400/121293332/e3850982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121300000/121293400/121293332/fdece1a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer](https://images.trvl-media.com/lodging/122000000/121300000/121293400/121293332/81589da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer](https://images.trvl-media.com/lodging/122000000/121300000/121293400/121293332/1a6190e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MAZZINI SUITES [](https://www.expedia.co.uk/Milan-Hotels-MAZZINI-SUITES.h121293332.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 9.2/10 Wonderful (18 reviews) "Suites were nice , excellent location with metro and shops nearby . Easy check-in and to check out at 3..30am and staff made it easy ." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sukhvinder £169 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Milan-Hotels-MAZZINI-SUITES.h121293332.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/100000000/99910000/99900500/99900463/a5f24706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Hot Tub | Private spa tub](https://images.trvl-media.com/lodging/100000000/99910000/99900500/99900463/670758bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Suite | 1 bedroom, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/100000000/99910000/99900500/99900463/881daf04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Suite | 1 bedroom, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/100000000/99910000/99900500/99900463/ebc03a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Prestige Boutique Homes Aparthotel Piazza Duomo View [](https://www.expedia.co.uk/Milan-Hotels-Prestige-Boutique-Homes-Pza-Duomo-View.h99900463.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 9.4/10 Exceptional (49 reviews) "The staff were phenomenal and very courteous. Checked in daily and asked if we needed anything. Location was perfect right next to the Metro and the Duomo. It was very convenient and accessible to shopping and activities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tara £287 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Milan-Hotels-Prestige-Boutique-Homes-Pza-Duomo-View.h99900463.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/749558de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/34c68267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![43-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/35ef0a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Studio, 1 Bedroom (Via dei Piatti 4) | Terrace/patio](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/a4cc8746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Milan Retreats Duomo [](https://www.expedia.co.uk/Milan-Hotels-Milan-Retreats-Duomo.h44236363.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 9.2/10 Wonderful (743 reviews) "Clean room and a great location. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Gregorio £134 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Milan-Hotels-Milan-Retreats-Duomo.h44236363.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42250000/42246100/42246071/w5755h3835x5y5-93f455a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/43000000/42250000/42246100/42246071/a911d525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/43000000/42250000/42246100/42246071/w5757h3835x0y5-eb981d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Studio Suite (Junior Queen/Two Twin Beds Suite) | Down duvets, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/43000000/42250000/42246100/42246071/efdfea6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Matilde Boutique Hotel, WorldHotels Elite [](https://www.expedia.co.uk/Milan-Hotels-Matilde-Boutique-Hotel.h42246071.Hotel-Information) Centro Storico, 0.1 mi from San Sebastiano 9.2/10 Wonderful (156 reviews) "Excellent stay…" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah G £345 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Milan-Hotels-Matilde-Boutique-Hotel.h42246071.Hotel-Information) ![Deluxe Double Room, Balcony, City View | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/7000000/6450000/6443200/6443123/98ea8480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Kitchenette | Living area | Flat-screen TV, first-run films](https://images.trvl-media.com/lodging/7000000/6450000/6443200/6443123/c3da95ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Kitchenette | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/7000000/6450000/6443200/6443123/9b897292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Kitchenette | Living area | Flat-screen TV, first-run films](https://images.trvl-media.com/lodging/7000000/6450000/6443200/6443123/5836f8e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Suite Milano Duomo [](https://www.expedia.co.uk/Milan-Hotels-Luxury-Suite-Milano-Duomo.h6443123.Hotel-Information) Centro Storico, 0.2 mi from San Sebastiano 9.4/10 Exceptional (237 reviews) "Beds were very comfortable, location was awesome " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nadia £230 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-Luxury-Suite-Milano-Duomo.h6443123.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665804/0fe68448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665804/22328428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665804/b2416364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite | Down duvets, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665804/827f20d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Touring Club Milan, A Radisson Collection Hotel [](https://www.expedia.co.uk/Milan-Hotels-Radisson-Collection-Palazzo-Touring-Club.h64665804.Hotel-Information) Centro Storico, 0.2 mi from San Sebastiano 9.4/10 Exceptional (205 reviews) "Great property- always top notch service and location cannot be beat!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom £359 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Milan-Hotels-Radisson-Collection-Palazzo-Touring-Club.h64665804.Hotel-Information) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/49000000/48710000/48703800/48703782/b4b8ffac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/49000000/48710000/48703800/48703782/537b714f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/49000000/48710000/48703800/48703782/df01c43c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![48-inch flat-screen TV with cable channels](https://images.trvl-media.com/lodging/49000000/48710000/48703800/48703782/b4abee28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ODSweet Duomo Milano Hotel [](https://www.expedia.co.uk/Milan-Hotels-ODSweet-Duomo-Milano-Hotel.h48703782.Hotel-Information) Centro Storico, 0.2 mi from San Sebastiano 9.2/10 Wonderful (178 reviews) "I love this hotel, the room was beautiful, the rooftop restaurant was amazing and the staff as well." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roslyn £283 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-ODSweet-Duomo-Milano-Hotel.h48703782.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/980000/977300/977287/7fd0e2d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (MONTENAPOLEONE) | Terrace/patio](https://images.trvl-media.com/lodging/1000000/980000/977300/977287/de2def82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977287/de9ad9d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Park King) | Bathroom | Designer toiletries, hair dryer, bidet, towels](https://images.trvl-media.com/lodging/1000000/980000/977300/977287/88917178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Hyatt Milano [](https://www.expedia.co.uk/Milan-Hotels-Park-Hyatt-Milano.h977287.Hotel-Information) Centro Storico, 0.3 mi from San Sebastiano 9.6/10 Exceptional (287 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa £1,216 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-Park-Hyatt-Milano.h977287.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12540000/12539500/12539421/98b1d589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12540000/12539500/12539421/e99c31f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12540000/12539500/12539421/8ea071fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12540000/12539500/12539421/ba3f1ca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ostello Bello Milano Duomo [](https://www.expedia.co.uk/Milan-Hotels-Ostello-Bello.h12539421.Hotel-Information) 0.3 mi from San Sebastiano 9.4/10 Exceptional (265 reviews) "Very well ran with great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brendan £124 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Milan-Hotels-Ostello-Bello.h12539421.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-15&endDate=2026-04-16®ionId=553248621532507514&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top San Sebastiano Hotel Reviews ![Hotel Dei Cavalieri Milano Duomo](https://images.trvl-media.com/lodging/1000000/20000/12900/12833/330dba44_y.jpg) ### Hotel Dei Cavalieri Milano Duomo 10/10 Excellent "Ms. Serena from the front desk was very kind to us. " [](https://expedia.co.uk/Milan-Hotels-Hotel-Dei-Cavalieri-Milano-Duomo.h12833.Hotel-Information) ![Hotel Berna](https://images.trvl-media.com/lodging/1000000/30000/26300/26287/162f6716_y.jpg) ### Hotel Berna 10/10 Excellent "The breakfast buffet was excellent. " [](https://expedia.co.uk/Milan-Hotels-Hotel-Berna.h26287.Hotel-Information) ![Rosa Grand Milano - Starhotels Collezione](https://images.trvl-media.com/lodging/1000000/10000/2900/2875/0f96b8f5_y.jpg) ### Rosa Grand Milano - Starhotels Collezione 10/10 Excellent "Breakfast was a huge selection! Rooms and amenities were one of kind! Very classy" [](https://expedia.co.uk/Milan-Hotels-Rosa-Grand-Milano-Starhotels-Collezione.h2875.Hotel-Information) ![Hotel Brunelleschi](https://images.trvl-media.com/lodging/1000000/20000/14300/14220/d215030e_y.jpg) ### Hotel Brunelleschi 10/10 Excellent "Room is clean, breakfast is good, and staff is friendly. Location is very convenient." [](https://expedia.co.uk/Milan-Hotels-Hotel-Brunelleschi.h14220.Hotel-Information) ![Tivoli President Milano Hotel](https://images.trvl-media.com/lodging/1000000/10000/2100/2095/8098e8aa_y.jpg) ### Tivoli President Milano Hotel 8/10 Good "Clean room, good bar" [](https://expedia.co.uk/Milan-Hotels-NH-Collection-Milano-President.h2095.Hotel-Information) ![Milan Retreats Duomo](https://images.trvl-media.com/lodging/45000000/44240000/44236400/44236363/749558de_y.jpg) ### Milan Retreats Duomo 10/10 Excellent "Great location. Easy check in. Loved it." [](https://expedia.co.uk/Milan-Hotels-Milan-Retreats-Duomo.h44236363.Hotel-Information) ![Hotel Rio](https://images.trvl-media.com/lodging/18000000/17750000/17748900/17748884/611028e0_y.jpg) ### Hotel Rio 8/10 Good "The room was tidy, although the bathroom was tired and cramped" [](https://expedia.co.uk/Milan-Hotels-Hotel-Rio.h17748884.Hotel-Information) ![Sina De la Ville](https://images.trvl-media.com/lodging/1000000/30000/20200/20187/716aa47b_y.jpg) ### Sina De la Ville 6/10 Okay "Great location, good staff, spacious room. However, the hotel building AC was only operating on heating mode (as it was end of March) and the room was too warm and therefore difficult to sleep in (had to open windows, but close them before sleeping due to the street noise). Breakfast quality was below average. " [](https://expedia.co.uk/Milan-Hotels-Sina-De-La-Ville.h20187.Hotel-Information) ![ibis Milano Centro](https://images.trvl-media.com/lodging/1000000/910000/905600/905544/3201398a_y.jpg) ### ibis Milano Centro 10/10 Excellent "Easy and well positioned" [](https://expedia.co.uk/Milan-Hotels-Ibis-Milano-Centro.h905544.Hotel-Information) ## Hotels near other San Sebastiano attractions ### Biblioteca Ambrosiana One of Europe’s first public libraries is home to Leonardo da Vinci’s Codex Atlanticus, which is housed alongside a huge book and art collection. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6077526) ### Via Torino During your visit to Milan, you can browse for the perfect souvenirs at Via Torino. Make time to visit the area's stunning cathedral or simply enjoy its charming cafes. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6216999) ### Chiesa di San Sepolcro Chiesa di San Sepolcro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Discover the area's acclaimed art galleries and shops. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532507515) ### Chiesa di Sant'Alessandro in Zebedia Chiesa di Sant'Alessandro in Zebedia is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's shops or stunning cathedral to your travel plans. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532506989) ### Chiesa Santa Maria Presso di San Satiro Chiesa Santa Maria Presso di San Satiro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's stunning cathedral or shops to your travel plans. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6077542) ### Museo Mangini Bonomi You can study the exhibits at Museo Mangini Bonomi, a museum with a storied past, during your holiday in Milan. Experience the area's acclaimed art galleries and fascinating museums. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532507512) ### Casa Ferrario You can study the exhibits at Casa Ferrario, a museum with a storied past, during your trip to Milan. Discover the area's fascinating museums and shops. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532507506) ### Church of San Giorgio al Palazzo Church of San Giorgio al Palazzo is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Discover the area's fascinating museums and stunning cathedral. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532506040) ## Frequently asked questions ### What's the area like around San Sebastiano? ### What's the best place to stay near San Sebastiano? ### How many hotels will I be able to find close to San Sebastiano? ### If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund? ### What can I see and do near San Sebastiano? ### How can I get to San Sebastiano?