A harbor with numerous boats, cranes, and a cityscape in the background.

San Antonio Holidays

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  • Your San Antonio Holiday

    Put together a custom holiday package to San Antonio and get ready to experience this incredible city how you like. Consider staying in the neighbourhood of Llolleo, which is great for coastal beaches and much more. Fill your spare time with visits to Rocas de Santo Domingo Beach, Vina Casa Marin Winery and Rocas de Santo Domingo Golf Club, some of the things you should see during your trip to San Antonio. Don't delay exploring this city any longer. Your dream San Antonio holiday is a couple of clicks away with Expedia.

    Discover the most popular places to visit in San Antonio

    Hacienda San Juan

    You can enjoy a tasting or tour at Hacienda San Juan during your travels to San Antonio. While you're in the area, stroll along the marina.

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    Centro Cultural San Antonio

    Enjoy an outing to Centro Cultural San Antonio during your stay in San Antonio. While you're in the area, stroll along the marina.

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    Centro Cultural de San Antonio

    Enjoy an outing to Centro Cultural de San Antonio during your stay in San Antonio. While you're in the area, stroll along the marina.

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    What to do in San Antonio

    Full Day Tour Isla Negra Island + Pomaire + Undurraga Vineyard from Santiago

    Isla Negra, Pablo Neruda's House, and San Alfonso del Mar

    £90

    per adult

    0% of travellers recommend

    Pablo Neruda's House in Isla Negra

    Full Day Trip to Isla Negra, San Alfonso & Undurraga Vineyard

    £67

    per adult

    0% of travellers recommend

    Isla Negra with Undurraga

    Isla Negra with Undurraga

    £90

    per adult

    0% of travellers recommend

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    San Antonio Hotel Deals

    Hotel Puerto Mayor

    A wooden building with a curved roof, surrounded by a well-maintained garden with various plants and flowers.
    • Address: Av 21 de Mayo 758, San Antonio, 2661336, CL
    • Location: 0.4 mi from San Antonio
    • Star rating: 3/5
    • Guest rating: 7.2/10 (Good, 40 reviews)
    • Price: £60, 17 Nov - 18 Nov
    • Review: I had a very nice stay at the Puerto Mayor. It was a good value for the cost especially since it included breakfast. The hotel personnel were pleasant and the room was quiet. I stayed there before a cruise and the cab ride to the terminal only took a few minutes. That was a real convenience. The hotel was within sight of the ship and no hotel was any nearer. I got to San Antonio by bus from Santiago and the taxi ride from the bus terminal to the hotel only took about 15 minutes.

    Hostal el Campito

    A room with a curved staircase, a dining area with a table and chairs, and large windows with a view of the outdoors.
    • Address: 323 Chorrillos, San Antonio, Valparaíso, 2661250, CL
    • Location: 0.7 mi from San Antonio
    • Star rating: 1/5
    • Price: £21, 13 Nov - 14 Nov

    Hotel Boutique Lagunillas Casablanca

    A swimming pool with a red edge, lounge chairs, and a person in the water.
    • Address: Avenida Rojas Montt, sitio 11, Casablanca, 2480000, CL
    • Location: 13.7 mi from San Antonio
    • Star rating: 3.5/5
    • Guest rating: 9.4/10 (Exceptional, 52 reviews)
    • Price: £182, 16 Nov - 17 Nov
    • Review: Don’t ecpect any ammenities on your room. Not even water, coffee or tea. For a cup of coffee needed to wait till 8:30am. Bugs all over the bed. Not worth the price at all.

    B&B Rocas Santo Domingo

    A spacious living area with a high ceiling, wooden beams, a dining table with chairs, and a fruit bowl.
    • Address: Central 24, Santo Domingo, San Antonio, CL
    • Location: 4.4 mi from San Antonio
    • Star rating: 3/5
    • Guest rating: 9.8/10 (Exceptional, 28 reviews)
    • Price: £94, 13 Nov - 14 Nov
    • Review: This place is an absolute gym. Alejandra and Jorge are the friendliest people and make you feel so welcome that it feels like home. For breakfast she had fresh juice, watermelon juice that was to die for. I will definitely be back because I felt like family.

    Cinque Colori

    A wooden deck with a green plastic chair, a view of the ocean, and a building with a window.
    • Address: Vicuña Mackenna 395, Algarrobo, Valparaiso, 2710000, CL
    • Location: 17.3 mi from San Antonio
    • Star rating: 3/5
    • Guest rating: 9.4/10 (Exceptional, 54 reviews)
    • Price: £67, 15 Nov - 16 Nov
    • Review: "Hermosa habitación desde la que se ve y escucha el mar, amplia, con pequeñita terraza (3er piso). El lugar es privilegiado ya que esta frente a playa tranquila y de vista despejada (sin edificios), buen desayuno y goza de silencio lo que es un privilegio. La atención del personal puede mejorarse con capacitación (escuchar al cliente y estar disponible en recepción si quiere considerarse hotel), la limpieza es impresionante en cafa rincón de la casa, bosca en el 1er piso posee un calido living...

    Centro Turístico Cabañas Quirinal

    A wooden sign with 'Quirinal' written on it, flanked by two gates.
    • Address: 747 Avenida Las Salinas, El Tabo, Región de Valparaíso, 2690000, CL
    • Location: 6 mi from San Antonio
    • Star rating: 2.5/5
    • Guest rating: 9.6/10 (Exceptional, 4 reviews)
    • Price: £71, 13 Nov - 14 Nov
    • Review: Clean Kind and courteous staff

    Departamento en Santo domingo Tricao

    A bedroom with a bed, a TV, and a balcony with a view of trees.
    • Address: Los eucaliptus, Santo Domingo, Valparaíso, 2720000, CL
    • Location: 4.4 mi from San Antonio
    • Star rating: 2.5/5
    • Price: £173, additional charges may apply, 30 Nov - 1 Dec

    Winery Boutique Hotel

    A balcony with wicker furniture and a potted plant, overlooking a coastal view with houses and boats.
    • Address: Avenida Dr. Guillermo Mucke 110, Algarrobo, Valparaiso, 2710000, CL
    • Location: 15.3 mi from San Antonio
    • Star rating: 4/5
    • Guest rating: 7.6/10 (Good, 43 reviews)
    • Price: £62, 15 Nov - 16 Nov
    • Review: Photos online are dated and do not reflect the poor quality of the room condition. We paid to stay in the top room, yet no working wifi, extremely tatty furniture, bathroom and ill fitting wood effect floors. No cupboards for hanging clothes and difficult to navigate to the room as in an extension, with no lift, narrow corridors and stairs. For the price, it is extremely expensive with a cheap breakfast. Better to stay in some of the wonderful new beachfront apartments on Air BnB.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Frequently Asked Questions

    How much does a San Antonio travel package cost?

    Our San Antonio packages, which start at just , are an ideal way to save big bucks. Pick your preferred hotels, flights and more to create your ideal itinerary.

    If I'm not able to travel, can I cancel my San Antonio travel package?

    Because we know life can throw you a few curveballs, the answer is yes. For further details, head to our Customer Service Portal. But generally speaking, if you've booked your package in the last 24 hours, you may be able to change or cancel it for free. Your airline, hotel or car rental company may charge a fee if you made your booking a while ago.

    How do I get a cheap travel package to San Antonio?

    Track down flights that fit your schedule, add a hotel to your booking and watch the savings stack up with a San Antonio travel package. It's that easy! From hotels and flights to rental cars and activities, Expedia makes travelling on the cheap easy. And with more than 550 airlines and 1,000,000 hotel options globally to select from, you won't be short of choice.

    Does Expedia offer Book Now, Pay Later San Antonio holidays?

    Good news! We do. Expedia has teamed up with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply pick the payment plan that suits you best during checkout and take the stress out of budgeting for your next trip. Remember to bundle your flights, accommodation and activities with Expedia to get the biggest bang for your holiday buck. Browse our flexible payment options below:

    • Pay monthly holidays: If paying bite-sized amounts each month is something that would work for you, Klarna offers just that! Paying in convenient monthly instalments will make that dream holiday possible.
    • Pay in instalments holidays: Like the idea of paying down your holiday in multiple transactions? Consider this Book Now, Pay Later option with Klarna.
    • Low deposit holidays: Hitting the "book now" button is easier with this payment plan. Put down a small deposit on your holiday and then start packing your suitcase.

    Where should I stay in San Antonio?

    With loads to explore in San Antonio, we suggest you lock in a hotel close to its attractions. San Antonio Port, Hacienda San Juan and Maípo River Wetland Park are some good ones to add to your itinerary.

    What are the top hotels in San Antonio?

    Get your trip off to a fantastic start by booking a stay at Hotel Casino San Antonio by Enjoy. It's one of most sought-after hotels in San Antonio. Another comfortable option is Winery Boutique Hotel.

    How far in advance should I book my San Antonio holiday?

    It all depends on the air carrier, but you can normally look up international flights on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally nab a cheaper seat only weeks before their intended journey.

    What does an Expedia San Antonio travel package include?

    That depends on what you're looking for. If you're travelling alone, you might decide to bundle flights and hotels. Bringing the whole crew to San Antonio? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the flexibility to tailor-make your travel package.

    What should I know before booking a San Antonio travel package?

    When you book your flights, hotels and car rentals together, you'll pick up incredible discounts. Whether you're planning an island getaway in a villa or want to stay in a convenient hotel in the city, Expedia will help make it happen.

    Can I choose my airline with a San Antonio Expedia travel package?

    With a travel package, you're the one in charge. Whether you'd prefer to fly to San Antonio in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.

    * Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.