San Antonio Holidays from £1,043

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Your San Antonio Holiday

Put together a custom holiday package to San Antonio and get ready to experience this incredible city how you like. Consider staying in the neighbourhood of Llolleo, which is great for coastal beaches and much more. Fill your spare time with visits to Rocas de Santo Domingo Beach, Vina Casa Marin Winery and Rocas de Santo Domingo Golf Club, some of the things you should see during your trip to San Antonio. Don't delay exploring this city any longer. Your dream San Antonio holiday is a couple of clicks away with Expedia.

Top San Antonio Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Boutique Castillo Rojo

Hotel Boutique Castillo Rojo

4 out of 5
Bellavista
Price was £1,130, price is now £1,043 per person
£1,043
per person
29 Sept - 4 Oct
found 20 hours ago
Return direct flight included
London (LON) to Santiago (SCL)
9.6/10 Exceptional! (610 reviews)
Really fun stay good location

Reviewed on 8 Jul 2025

Le Rêve Boutique Hotel

Le Rêve Boutique Hotel

4 out of 5
Providencia
Price was £1,354, price is now £1,203 per person
£1,203
per person
29 Sept - 4 Oct
found 20 hours ago
Return direct flight included
London (LON) to Santiago (SCL)
9.8/10 Exceptional! (446 reviews)
Great location, we walked to San Cristobal Hill and local dining and took a short Uber ride to the Palace, Plaza del Armas and other downtown sites. Jose organized pickup from the airport and transfers to and from Valle Nevado. The breakfast was good, tea, coffee and water available all day. Great stay.

Reviewed on 17 Aug 2025

Casa Bueras Boutique Hotel

Casa Bueras Boutique Hotel

4.5 out of 5
Downtown Santiago
Price was £1,169, price is now £1,044 per person
£1,044
per person
29 Sept - 4 Oct
found 20 hours ago
Return direct flight included
London (LON) to Santiago (SCL)
9.2/10 Wonderful! (496 reviews)
The hotel staff was really accommodating and attentive. The breakfast was delicious and our room was spacious and quiet. Also, the hotel is neat, clean and beautifully decorated!

Reviewed on 28 Jun 2025

Hotel Plaza San Francisco

Hotel Plaza San Francisco

4 out of 5
Downtown Santiago
Price was £1,252, price is now £1,125 per person
£1,125
per person
29 Sept - 4 Oct
found 20 hours ago
Return direct flight included
London (LON) to Santiago (SCL)
9.2/10 Wonderful! (929 reviews)
Extra friendly staff! Great gym and breakfast

Reviewed on 8 Jun 2025

Best Western Premier Marina Las Condes

Best Western Premier Marina Las Condes

4 out of 5
Las Condes
Price was £1,530, price is now £1,378 per person
£1,378
per person
29 Sept - 4 Oct
found 20 hours ago
Return direct flight included
London (LON) to Santiago (SCL)
9/10 Wonderful! (895 reviews)
Overall I would recommend however I knocked a star off as although the reception areas/restaurants are 4*, the rooms are a bit basic and feel like they need some TLC compared to other 4* I have stayed in. Special thanks go to the especially friendly and helpful concierge/doormen! If I were to stay in Santiago again I’d likely consider Bellavista/downtown as I personally found Las Condes a bit quiet and further out than ideal. Also ate at the restaurant several times and the food is amazing.

Reviewed on 5 Jul 2025

San Antonio Essential Information

Language
Spanish
Currency
Chilean pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
85,700
Max Temp Winter
18ºC
Max Temp Summer
27ºC
Top Sights
Rocas de Santo Domingo Beach, Pablo Neruda Museum and Vina Casa Marin Winery

Top hotels in San Antonio

Hotel Casino San Antonio by Enjoy

Hotel Casino San Antonio by Enjoy

3.5 out of 5
Dr. Nestor Fernandez Thomas No. 83, San Antonio
Fully refundableReserve now, pay when you stay
The price is £51 per night from 17 Sept to 18 Sept
£51
17 Sept - 18 Sept
7.8/10 Good! (312 reviews)
"Very nice hotel with a GREAT VIEW, one thing they have to inpruve, they dont have a restaurant, they said that soon is coming one"

Reviewed on 20 Apr 2025

Hotel Casino San Antonio by Enjoy
Hotel Puerto Mayor

Hotel Puerto Mayor

3 out of 5
Av 21 de Mayo 758, San Antonio
Great Location for a pre–Ocean Cruise Stay
"I had a very nice stay at the Puerto Mayor. It was a good value for the cost especially since it included breakfast. The hotel personnel were pleasant and the room was quiet. I stayed there before a cruise and the cab ride to the terminal only took a few minutes. That was a real convenience. The ..."

Reviewed on 17 Apr 2023

Get rates
Hotel Puerto Mayor
Hostal el Campito

Hostal el Campito

1 out of 5
323 Chorrillos, San Antonio, Valparaíso
The price is £38 per night from 26 Aug to 27 Aug
£38
26 Aug - 27 Aug
Hostal el Campito
See all 167 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
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Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in San Antonio

Full Day Private Shore Tour Santiago from San Antonio Cruise Port

Full Day Private Shore Tour Santiago from San Antonio Cruise Port

£246
per adult
Full Day Private Shore Tour Santiago from San Antonio Cruise Port
Tour to Parque Tricao + Aviario and Pomaire full day from Santiago

Tour to Parque Tricao + Aviario and Pomaire full day from Santiago

£133
per adult
Tour to Parque Tricao + Aviario and Pomaire full day from Santiago
Discover the Tricao Park Aviary in a Full Day

Tricao Park full day - The largest aviary in LATAM

£124
per adult
Tricao Park full day - The largest aviary in LATAM
See all activities in San Antonio

Frequently asked questions

How much does a San Antonio travel package cost?
Our San Antonio packages, which start at just £1,043, are an ideal way to save big bucks. Pick your preferred hotels, flights and more to create your ideal itinerary.
If I'm not able to travel, can I cancel my San Antonio travel package?
Because we know life can throw you a few curveballs, the answer is yes. For further details, head to our Customer Service Portal. But generally speaking, if you've booked your package in the last 24 hours, you may be able to change or cancel it for free. Your airline, hotel or car rental company may charge a fee if you made your booking a while ago.
How do I get a cheap travel package to San Antonio?
Track down flights that fit your schedule, add a hotel to your booking and watch the savings stack up with a San Antonio travel package. It's that easy! From hotels and flights to rental cars and activities, Expedia makes travelling on the cheap easy. And with more than 550 airlines and 1,000,000 hotel options globally to select from, you won't be short of choice.
Does Expedia offer Book Now, Pay Later San Antonio holidays?
Good news! We do. Expedia has teamed up with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply pick the payment plan that suits you best during checkout and take the stress out of budgeting for your next trip. Remember to bundle your flights, accommodation and activities with Expedia to get the biggest bang for your holiday buck. Browse our flexible payment options below:

  • Pay monthly holidays: If paying bite-sized amounts each month is something that would work for you, Klarna offers just that! Paying in convenient monthly instalments will make that dream holiday possible.
  • Pay in instalments holidays: Like the idea of paying down your holiday in multiple transactions? Consider this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: Hitting the "book now" button is easier with this payment plan. Put down a small deposit on your holiday and then start packing your suitcase.

Where should I stay in San Antonio?
With loads to explore in San Antonio, we suggest you lock in a hotel close to its attractions. San Antonio Port, Hacienda San Juan and Maípo River Wetland Park are some good ones to add to your itinerary.
What are the top hotels in San Antonio?
Get your trip off to a fantastic start by booking a stay at Hotel Casino San Antonio by Enjoy. It's one of most sought-after hotels in San Antonio. Another comfortable option is Winery Boutique Hotel.
How far in advance should I book my San Antonio holiday?
It all depends on the air carrier, but you can normally look up international flights on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally nab a cheaper seat only weeks before their intended journey.
What does an Expedia San Antonio travel package include?
That depends on what you're looking for. If you're travelling alone, you might decide to bundle flights and hotels. Bringing the whole crew to San Antonio? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the flexibility to tailor-make your travel package.
What should I know before booking a San Antonio travel package?
When you book your flights, hotels and car rentals together, you'll pick up incredible discounts. Whether you're planning an island getaway in a villa or want to stay in a convenient hotel in the city, Expedia will help make it happen.
Can I choose my airline with a San Antonio Expedia travel package?
With a travel package, you're the one in charge. Whether you'd prefer to fly to San Antonio in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.