Río Sereno Holidays from £349
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top Río Sereno Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
MARINN PLACE Financial District
Bella Vista
Price was £464, price is now £349 per person
£349
per person
2 Aug - 6 Aug
found 1 day ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
9/10 Wonderful! (359 reviews)
Friendly staff and the bed was very comfortable as usual. Breakfast was good and I noticed the restaurant was remodeled to a modern esthetic. It was an overall good stay and I will be staying there again on my next trip to Panama.
Reviewed on 31 May 2026
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was £942, price is now £463 per person
£463
per person
2 Aug - 6 Aug
found 12 hours ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
9.2/10 Wonderful! (1,003 reviews)
The location is great !,
Great food and service !
Reviewed on 29 May 2026
Megapolis Hotel Panamá
San Francisco
Save 100% on your flight
Price was £777, price is now £489 per person
£489
per person
2 Aug - 6 Aug
found 1 day ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
8.4/10 Very Good! (1,538 reviews)
La habitación tenia una hermosa vista, muy limpia, desde nuestra llegada su personal fue correcta, amable y muy servicial, los desayunos fueron exquisitos a otro nivel y había de todo muy cerca de todo.
Reviewed on 26 May 2026
Sofitel Legend Casco Viejo, Panama City
Casco Viejo
Save 100% on your flight
Price was £1,156, price is now £813 per person
£813
per person
2 Aug - 6 Aug
found 12 hours ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
9.8/10 Exceptional! (654 reviews)
My friends and I booked a room here and loved it so much. We spent one day at the pool and Kevin was so accommodating to our needs. The entire team we came across had such a pleasant aura and the property is absolutely beautiful.
Reviewed on 31 May 2026
Top hotels in Río Sereno
Hotel Finca Lerida
Alto Quiel Los Naranjos Chiriqui
The price is £120 per night from 9 Jun to 10 Jun
£120
9 Jun - 10 Jun
includes taxes & fees
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Volcan, Via Cerro Punta Volcan Chiriqui
Fully refundable
The price is £93 per night from 10 Jun to 11 Jun
£93
10 Jun - 11 Jun
includes taxes & fees
8.2/10 Very Good! (260 reviews)
"I really like the restaurant attendants the were very helpful"
Reviewed on 25 May 2026
Casa Grande Bambito Resort
Calle El Manantial Paso Ancho Chiriqui
8.4/10 Very Good! (99 reviews)
"We went for 3 days to the Junior Suite 1. First day there was a wedding. Noise all night long When we got there, the TV did not work. Wifi slow and sometimes it went down. Antes on the sink, the staff told me that "usually happens". No mosquito screen. You need to sleep with windows opens, which ..."
Reviewed on 15 Jan 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
