Default HTG hotel image

Search Hotels Near Poplar Bluff Regional Medical Center, Poplar Bluff

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Filter by

Star rating

Guest rating

Our top choices for Poplar Bluff Regional Medical Center hotels

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.
Terrace/patio
Exterior
Pool

1. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
0.8 mi from Poplar Bluff Regional Medical Center
United States
Rhonda
£77
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Poplar Bluff
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
A corner market with a refrigerated display case and a pantry area.
A reception area with a wooden counter, a coffee machine, and a display of pastries.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

2. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
0.1 mi from Poplar Bluff Regional Medical Center
United States
Vicki
£86
includes taxes & fees
11 Oct - 12 Oct
Fairfield Inn & Suites by Marriott Poplar Bluff
A spacious lobby with a reception desk, seating area, and large windows.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
An indoor swimming pool with a clear view of the outside through large windows.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

3. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
1.1 mi from Poplar Bluff Regional Medical Center
United States
Dean
£80
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Poplar Bluff
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.
A motel with a prominent '66' sign, large windows, and a flat roof.

4. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
1.3 mi from Poplar Bluff Regional Medical Center
United States
Cindy
£67
includes taxes & fees
5 Oct - 6 Oct
Motel 6 Poplar Bluff, MO
A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.
A hotel lobby with a coffee station, seating area, and a television screen.
A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.
A hotel with a covered entrance, multiple windows, and a yellow facade.

5. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
1 mi from Poplar Bluff Regional Medical Center
United States
Muhammad
£64
includes taxes & fees
1 Nov - 2 Nov
Comfort Inn Poplar Bluff North
A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.
A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.
A laundry area with two stacked washers and dryers, a control panel, and a beige wall with a wooden panel above the dryers.
A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

6. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
0.7 mi from Poplar Bluff Regional Medical Center
United States
Diana
£57
includes taxes & fees
17 Oct - 18 Oct
Super 8 by Wyndham Poplar Bluff Missouri
A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.
A wooden deck with a railing leading to a building with a metal roof and a brown door.
A calm lake with a wooden dock and a forested island in the distance.
A bedroom with a wooden bed, a bench, and a window.

7. Lake Wappapello

Lake Wappapello
3.7 mi from Poplar Bluff Regional Medical Center
United States
Tonya
£72
includes taxes & fees
5 Oct - 6 Oct
Lake Wappapello
View all properties

Compare popular hotels close to Poplar Bluff Regional Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.
Hampton Inn Poplar Bluff
9.4
Exceptional
960 reviews
View
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
Fairfield Inn & Suites by Marriott Poplar Bluff
9.4
Exceptional
966 reviews
View
A spacious lobby with a reception desk, seating area, and large windows.
Drury Inn & Suites Poplar Bluff
9.4
Exceptional
1,001 reviews
View
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
Motel 6 Poplar Bluff, MO
8.0
Very good
1,004 reviews
View
A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.
Comfort Inn Poplar Bluff North
7.8
Good
440 reviews
View

Top Poplar Bluff Regional Medical Center Hotel Reviews

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

10/10 Excellent
"Debbie at the front desk is perfect."
Tim 2-night trip
Posted 3 hours ago
Holiday Inn Poplar Bluff by IHG
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent
"Terrific base accommodation. Clean, efficient. I use this place whenever I’m in the area. I’m"
Herman 1-night trip
Posted 1 day ago
Motel 6 Poplar Bluff, MO
Home Sweet Home, Spacious Sunroom & Fun Deck!

Home Sweet Home, Spacious Sunroom & Fun Deck!

10/10 Excellent
"Ease of check in and out. Clean-Excellent sleeping space. Had everything we needed. Price reasonable-Loved our stay. If need to stay in area again, will definitely stay here."
Shirley O. 4-night trip
Posted 6 days ago
Home Sweet Home, Spacious Sunroom & Fun Deck!
Lake Wappapello

Lake Wappapello

10/10 Excellent
"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from the park. We ordered deli sandwiches from here and picked up some icecream. The sandwiches were delicious and the store had pretty much whatever you might need. The checkin process was great with good communication about which cabin to go to, what the door code was etc... We plan to come back for a longer stay so we can have another evening around the firepit and see all of the stars. Great place to stay."
Dottie 1-night trip
Posted 3 weeks ago
Lake Wappapello
40-Acre Poplar Bluff Nature Lovers Paradise!

40-Acre Poplar Bluff Nature Lovers Paradise!

10/10 Excellent
"A nice stay"
sandra p. 3-night trip
Posted 1 month ago
40-Acre Poplar Bluff Nature Lovers Paradise!
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

8/10 Good
"Everything was good"
Joshua L. 3-night trip
Posted 1 month ago
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Historic home in the heart of Poplar Bluff

Historic home in the heart of Poplar Bluff

10/10 Excellent
"What a unique stay! The most beautiful vrbo we have ever stayed in. Thank you so much!! As antique lovers this place was a total dream!!! Within walking distance from neat local restaurants and shops as well! "
Jonah B. 3-night trip
Posted 11 months ago
Historic home in the heart of Poplar Bluff

Frequently asked questions

What's the area like around Poplar Bluff Regional Medical Center?
Poplar Bluff Regional Medical Center is located in Poplar Bluff. Travellers like this family-friendly area for its restaurants. You'll find 19 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay near Poplar Bluff Regional Medical Center?
Adjacent to Poplar Bluff Regional Medical Center, Fairfield Inn & Suites by Marriott Poplar Bluff is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices within a short distance include Holiday Inn Poplar Bluff by IHG and Hampton Inn Poplar Bluff.
How many hotels will I be able to find close to Poplar Bluff Regional Medical Center?
Expedia has 19 hotels and other accommodation options a few miles from Poplar Bluff Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Poplar Bluff Regional Medical Center, will I receive a refund?
Yes, most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best deals available near Poplar Bluff Regional Medical Center.
What can I see and do near Poplar Bluff Regional Medical Center?
You'll want to browse the exhibits at Mo-Ark Regional Railroad Museum and Margaret Harwell Art Museum. You might plan a visit to Black River Coliseum or Ozark Ridge Golf Course while you're in the area. Poplar Bluff History Museum and North Main Street Historic District are both worth a visit while you're out exploring.