Title: The Best Hotels Closest to Opelousas Museum And Interpretive Center in Opelousas - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Opelousas](https://expedia.co.uk/Opelousas-Holiday-Rentals.d9235.Travel-Guide-HolidayRentals)[Opelousas Museum And Interpretive Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Opelousas-Museum-And-Interpretive-Center.d914100320129433600.Car-Hire-Guide)[Opelousas Museum And Interpretive Center Holidays](https://expedia.co.uk/Opelousas-Museum-And-Interpretive-Center-Opelousas.d914100320129433600.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [2 Apr - 3 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=914100320129433600&startDate=2026-04-02&endDate=2026-04-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Apr - 4 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=914100320129433600&startDate=2026-04-03&endDate=2026-04-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=914100320129433600&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=914100320129433600&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Opelousas Museum And Interpretive Center hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/808200/808193/2034d673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/808200/808193/841402c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/810000/808200/808193/7ca4b478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/810000/808200/808193/0f0d2f80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Opelousas by IHG [](https://www.expedia.co.uk/Lafayette-Hotels-Holiday-Inn-Hotel-Suites-Opelousas.h808193.Hotel-Information) 1.6 mi from Opelousas Museum And Interpretive Center 9.2/10 Wonderful (216 reviews) "Really enjoyed the stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felisha £116 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Lafayette-Hotels-Holiday-Inn-Hotel-Suites-Opelousas.h808193.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950153/575372e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950153/c29fe2ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950153/b10d15b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950153/69a91ca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Opelousas [](https://www.expedia.co.uk/Lafayette-Hotels-Hampton-Inn-Opelousas.h19950153.Hotel-Information) 1.3 mi from Opelousas Museum And Interpretive Center 8.4/10 Very good (354 reviews) "Staff was really kind and respectful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ella £101 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Lafayette-Hotels-Hampton-Inn-Opelousas.h19950153.Hotel-Information) ![Casino](https://images.trvl-media.com/lodging/5000000/4020000/4016100/4016020/c0a326e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4020000/4016100/4016020/816ac57f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4020000/4016100/4016020/f5e68e9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/5000000/4020000/4016100/4016020/f90a0ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Evangeline Downs Hotel, an Ascend Collection Hotel [](https://www.expedia.co.uk/Lafayette-Hotels-Evangeline-Downs-Hotel.h4016020.Hotel-Information) 1.4 mi from Opelousas Museum And Interpretive Center 8.2/10 Very good (764 reviews) "Everything was amazing… def coming back" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miranda £100 includes taxes & fees 27 Apr - 28 Apr [](https://www.expedia.co.uk/Lafayette-Hotels-Evangeline-Downs-Hotel.h4016020.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2570000/2561100/2561044/7e509cb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Opelousas [](https://www.expedia.co.uk/Opelousas-Hotels-Spark-By-Hilton-Opelousas.h2561044.Hotel-Information) 1.8 mi from Opelousas Museum And Interpretive Center 7.6/10 Good (401 reviews) "Everyone and everything in the room was amazing" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jasmie £79 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Opelousas-Hotels-Spark-By-Hilton-Opelousas.h2561044.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/520000/518600/518503/c9d67f60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/520000/518600/518503/9361e563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/520000/518600/518503/1bf717f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/520000/518600/518503/92112bca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Opelousas [](https://www.expedia.co.uk/Lafayette-Hotels-Days-Inn-Suites-By-Wyndham-Opelousas.h518503.Hotel-Information) 1.6 mi from Opelousas Museum And Interpretive Center 7.0/10 Good (717 reviews) "nice stay, clean room, and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alkinetta £62 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Lafayette-Hotels-Days-Inn-Suites-By-Wyndham-Opelousas.h518503.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/42100/42097/2a36eb20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, free toiletries, towels](https://images.trvl-media.com/lodging/1000000/50000/42100/42097/3a142bc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42100/42097/77fc3b83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/42100/42097/605abdfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Opelousas, LA [](https://www.expedia.co.uk/Opelousas-Hotels-Studio-6-Opelousas.h42097.Hotel-Information) 1.6 mi from Opelousas Museum And Interpretive Center 5.6/10 (267 reviews) "The worst stay ever." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diendre £58 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/Opelousas-Hotels-Studio-6-Opelousas.h42097.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21800/21762/59153378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21800/21762/7f44c8d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/21800/21762/b7f916a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/30000/21800/21762/d3faf5a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Opelousas, LA [](https://www.expedia.co.uk/Lafayette-Hotels-Motel-6-Opelousas.h21762.Hotel-Information) 4.1 mi from Opelousas Museum And Interpretive Center 6.8/10 (429 reviews) "Love it " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Imani £53 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Lafayette-Hotels-Motel-6-Opelousas.h21762.Hotel-Information) ![Hypo-allergenic bedding, free minibar items, desk, laptop workspace](https://images.trvl-media.com/lodging/108000000/107450000/107443300/107443289/8cd50107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107450000/107443300/107443289/413716ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/108000000/107450000/107443300/107443289/245ce14b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/108000000/107450000/107443300/107443289/985edc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Klaus [](https://www.expedia.co.uk/Washington-Hotels-Hotel-Klaus.h107443289.Hotel-Information) 5.7 mi from Opelousas Museum And Interpretive Center 9.8/10 Exceptional (43 reviews) "Great little boutique hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) robert £119 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Washington-Hotels-Hotel-Klaus.h107443289.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/108000000/107610000/107608900/107608870/c74ac47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/108000000/107610000/107608900/107608870/b6c07842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/108000000/107610000/107608900/107608870/901fa635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/108000000/107610000/107608900/107608870/3cce6893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lafleur Guest House [](https://www.expedia.co.uk/Washington-Hotels-Lafleur-Guest-House.h107608870.Hotel-Information) 5.7 mi from Opelousas Museum And Interpretive Center £173 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/Washington-Hotels-Lafleur-Guest-House.h107608870.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-16&endDate=2026-04-17®ionId=914100320129433600&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Opelousas Museum And Interpretive Center | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ----------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/808200/808193/2034d673.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express & Suites Opelousas by IHG | 3.0 star property | 9.2Wonderful216 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/20000000/19960000/19950200/19950153/575372e3.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn Opelousas | 2.5 star property | 8.4Very good354 reviews | View | | | | | | | ![Casino](https://images.trvl-media.com/lodging/5000000/4020000/4016100/4016020/c0a326e5.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Evangeline Downs Hotel, an Ascend Collection Hotel | 3.0 star property | 8.2Very good764 reviews | View | | | | | | | ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2570000/2561100/2561044/7e509cb0.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Spark by Hilton Opelousas | 2.5 star property | 7.6Good401 reviews | View | | | | | | | ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/520000/518600/518503/c9d67f60.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Days Inn & Suites by Wyndham Opelousas | 2.0 star property | 7.0Good717 reviews | View | | | | | | ## Top Opelousas Museum And Interpretive Center Hotel Reviews ![Days Inn & Suites by Wyndham Opelousas](https://images.trvl-media.com/lodging/1000000/520000/518600/518503/c9d67f60_y.jpg) ### Days Inn & Suites by Wyndham Opelousas 10/10 Excellent "Yes" [](https://expedia.co.uk/Lafayette-Hotels-Days-Inn-Suites-By-Wyndham-Opelousas.h518503.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Lafayette Oil Center](https://images.trvl-media.com/lodging/37000000/36490000/36485800/36485717/7d78deae_y.jpg) ### La Quinta Inn & Suites by Wyndham Lafayette Oil Center 8/10 Good "The breakfast was not that good. If you like breads and cereal and waffles, you’ll be fine. I need protein in the morning and the eggs and sausage were horrible. " [](https://expedia.co.uk/Lafayette-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Lafayette-Oil-Center.h36485717.Hotel-Information) ![Evangeline Downs Hotel, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/5000000/4020000/4016100/4016020/c0a326e5_y.jpg) ### Evangeline Downs Hotel, an Ascend Collection Hotel 6/10 Okay "Ben walls, scary elevator. Indoor pool was closed. Things were falling apart, subpar continental breakfast scariest elevator I have ever been on." [](https://expedia.co.uk/Lafayette-Hotels-Evangeline-Downs-Hotel.h4016020.Hotel-Information) ![Motel 6 Opelousas, LA](https://images.trvl-media.com/lodging/1000000/30000/21800/21762/59153378_y.jpg) ### Motel 6 Opelousas, LA 8/10 Good "The rooms are clean, it has a good parking lot, the staff is very friendly and the air conditioning works well, it also has a very good price. " [](https://expedia.co.uk/Lafayette-Hotels-Motel-6-Opelousas.h21762.Hotel-Information) ![Comfort Inn Lafayette North I-10](https://images.trvl-media.com/lodging/1000000/800000/793900/793828/7b0c226c_y.jpg) ### Comfort Inn Lafayette North I-10 6/10 Okay "The hotel staff was very kind. This is an older hotel that has had some updates. The room floor was not very clean, but the bathroom and beds had been cleaned. The night we stayed someone burnt toast in the lobby at 8am which resulted in the fire alarms going off and they had a hard time getting them to stop. We packed quickly and left because of the chaos." [](https://expedia.co.uk/Lafayette-Hotels-Baymont-By-Wyndham-Lafayette-Airport.h793828.Hotel-Information) ![Drury Inn & Suites Lafayette, LA](https://images.trvl-media.com/lodging/2000000/1080000/1076500/1076487/6860c646_y.jpg) ### Drury Inn & Suites Lafayette, LA 10/10 Excellent "Parking was safe and easy. The staff was very nice and gave good recommendations. " [](https://expedia.co.uk/Lafayette-Hotels-Drury-Inn-Suites-Lafayette.h1076487.Hotel-Information) ![Spark by Hilton Opelousas](https://images.trvl-media.com/lodging/3000000/2570000/2561100/2561044/7e509cb0_y.jpg) ### Spark by Hilton Opelousas 10/10 Excellent "Staff went above and beyond " [](https://expedia.co.uk/Opelousas-Hotels-Spark-By-Hilton-Opelousas.h2561044.Hotel-Information) ![Microtel Inn & Suites by Wyndham Scott/Lafayette](https://images.trvl-media.com/lodging/1000000/290000/285000/284947/ee48788f_y.jpg) ### Microtel Inn & Suites by Wyndham Scott/Lafayette 8/10 Good "I stay here often. Highl the" [](https://expedia.co.uk/Lafayette-Hotels-Microtel-Inn-Suites-By-Wyndham-ScottLafayette.h284947.Hotel-Information) ![Sonesta ES Suites Lafayette Airport Extended Stay ](https://images.trvl-media.com/lodging/1000000/130000/126800/126752/14f9621e_y.jpg) ### Sonesta ES Suites Lafayette Airport Extended Stay 8/10 Good "Na na na" [](https://expedia.co.uk/Lafayette-Hotels-Sonesta-ES-Suites-Lafayette-Airport.h126752.Hotel-Information) ## Hotels near other Opelousas Museum And Interpretive Center attractions ### Opelousas Public Library Opelousas Public Library is just one of the places to see in Opelousas, so why not enjoy the other things to explore during your travels? While in the area, you can find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=914103443738824704) ### Fireman's Museum You can spend an afternoon studying the exhibits at Fireman's Museum during your travels in Opelousas. While in the area, you can find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=914101638480969728) ### Opelousas Historic District Find out about the history of Opelousas when you spend time at Opelousas Historic District. While in the area, you can find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=914102549221654528) ### St. Landry Catholic Church 4.1/5 (26 reviews) After visiting St. Landry Catholic Church, make a plan to see the other sights and activities in Opelousas. While in the area, you can find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532644537) ### Louisiana Orphan Train Museum 4.0/5 (17 reviews) You can browse the exhibits at Louisiana Orphan Train Museum, a museum with a storied past, during your holiday in Opelousas. While in the area, you can find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532644536) ### Jim Bowie Museum You can spend an afternoon exploring the galleries in Jim Bowie Museum during your trip to Opelousas. While in the area, you can find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=914101626426593280) ### Rural African American Museum 4.2/5 (10 reviews) You can spend an afternoon exploring the galleries in Rural African American Museum during your trip to Opelousas. While in the area, you can find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=724958618887630848) ### North Park North Park is just one of the places to see in Opelousas, so why not enjoy the other things to explore during your travels? While in the area, you can find time to visit its casinos. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=914102600958394368) ## Frequently asked questions ### What's the area like around Opelousas Museum And Interpretive Center? ### Where is the best place to stay near Opelousas Museum And Interpretive Center? ### How many hotels can I expect to find close to Opelousas Museum And Interpretive Center? ### If I need to cancel the hotel reservation for my stay near Opelousas Museum And Interpretive Center, will I receive a refund?