Title: Hotels in Old Appleton, MO - Best Old Appleton Hotels from £48 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Old Appleton](https://expedia.co.uk/Old-Appleton-Holiday-Rentals.d553248634983492471.Travel-Guide-HolidayRentals)[Old Appleton Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Old-Appleton.d553248634983492471.Car-Hire-Guide)[Old Appleton Holidays](https://expedia.co.uk/Old-Appleton.d553248634983492471.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Old Appleton, MO from £48 ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Old Appleton Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&travelerType=family_friendly) ## Check prices for these dates Tonight [26 Sept - 27 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983492471&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983492471&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983492471&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983492471&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Old Appleton hotels and places to stay ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/4e8bbceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/7f26b79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville Perryville 8.4/10 Very good (912) " Love the stay and staff was great " £62 includes taxes & fees 2 Oct - 3 Oct [](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1016) "Was a clean room, nice staff, good parking " £71 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/668f3d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/d42a6e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG Perryville 9.4/10 Exceptional (510) "Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! " £72 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (625) "Friendly staff, very clean and pleasant environment." £68 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast ](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/6b56391d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/12e65c55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/082d2613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 Perryville 6.6/10 (118) "Right town, close to enough. " £58 includes taxes & fees 7 Oct - 8 Oct [](https://www.expedia.co.uk/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5dd1852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (414) "It was easy and quiet and an easy check in " £49 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/e7849830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/0ac21fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Desk, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/8b8e9c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville Perryville 6.8/10 (411) "Was a nice place." £61 includes taxes & fees 27 Sept - 28 Sept [](https://www.expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/9a57fa49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (643) "nice stay" £48 includes taxes & fees 2 Oct - 3 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/bb7f277a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/a758bb0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau Jackson 8.2/10 Very good (734) "Great area, fast check in, quiet, very spacious" £72 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau Cape Girardeau 9.6/10 Exceptional (65) "Great overall stay" £86 includes taxes & fees 2 Oct - 3 Oct [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=553248634983492471&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOld-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOld-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels) ## Top Old Appleton Hotel Reviews ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "this place is awesome! evening snacks and drinks (a meal really!) and very nice breakfast comfortable bed and beautiful grounds-quite rural, but Dairy Queen across the road. easy and safe seeming parking " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "Brand new hotel and it’s not even shown on Google maps. Great condition and service!" [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Town House Inn](//images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg) ### Town House Inn 10/10 Excellent "It was easy and quiet and an easy check in " [](https://expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Hot Tub & Creek Views: Secluded Perryville Cabin](//images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/762b23c1_y.jpg) ### Hot Tub & Creek Views: Secluded Perryville Cabin 10/10 Excellent "i stayed at the cabin for a week, and enjoyed the peace and quiet of being in the middle of nowhere. i took long walks with my dog, lounged in the hot tub (very nice), gathered eggs from the chickens, learned the history of the cabin, and got together with friends living close by. it's not too far away from perryville, so i made a few trips to town." [](https://expedia.co.uk/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115013833.Hotel-Information) ![Beautiful location in the secluded woods ](//images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/193ecf29_y.jpg) ### Beautiful location in the secluded woods 10/10 Excellent "This was an amazing getaway! So secluded and private....surrounded by nature..." [](https://expedia.co.uk/Pomona-Hotels-Beautiful-Location-In-The-Secluded-Woods.h103080140.Hotel-Information) ![Super 8 by Wyndham Perryville](//images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg) ### Super 8 by Wyndham Perryville 10/10 Excellent "The hotel is nice. Centrally located to Walmart Restaurants and Dispensary. The rooms are clean comfortable beds. The pool and gym are well maintained. The brea" [](https://expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Notting Hill Cottage](//images.trvl-media.com/lodging/49000000/49000000/48991900/48991852/9fab7427_y.jpg) ### Notting Hill Cottage 10/10 Excellent "We had an amazing girls' weekend at this beautiful cabin! The view was stunning, the decor cozy, and we enjoyed the hot tub. We loved catching up and making memories together. Can't wait to do it again!" [](https://expedia.co.uk/Alto-Pass-Hotels-Notting-Hill-Cottage.h48991852.Hotel-Information) ![Secluded Cabin. Art. Fast WiFi. Fireplace. New Kitchen](//images.trvl-media.com/lodging/20000000/19790000/19785200/19785140/0ef68f21_y.jpg) ### Secluded Cabin. Art. Fast WiFi. Fireplace. New Kitchen 10/10 Excellent "Our family had a great time. We did lots of hiking locally, visited a winery and a local orchard. We cooked our meals and the kitchen and grilled out with ease. Kids loved the loft beds to hang out and sleep. Daughter loved the butterflies outside too. It was close enough to travel to several trailheads with ease. You are a little ways from town which is a feature but make sure you are good on gas and groceries. We stopped at Kroger on our way in. " [](https://expedia.co.uk/Pomona-Hotels-Art-Fast-Wifi-Fire-Pit-New-Kitchen-Secluded.h19785140.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau](//images.trvl-media.com/lodging/104000000/103750000/103741400/103741323/503e8265_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau 8/10 Good "Nice place " [](https://expedia.co.uk/Jackson-Hotels-Best-Western-Plus-Jackson-Cape-Girardeau.h103741323.Hotel-Information) ## More cheap stays in Old Appleton ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St, Perryville, MO £72 12 Oct - 13 Oct includes taxes & fees 9.2/10 Wonderful! (508 reviews) [](https://expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Perryville 1119 Vincent Dr, Perryville, MO £62 2 Oct - 3 Oct includes taxes & fees 8.4/10 Very Good! (911 reviews) [](https://expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn 2011 North Kingshighway, Cape Girardeau, MO £48 2 Oct - 3 Oct includes taxes & fees 7/10 Good! (643 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Town House Inn 517 E Jackson Blvd, Jackson, MO £49 28 Sept - 29 Sept includes taxes & fees 7.6/10 Good! (414 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Cape Girardeau 2520 Veterans Memorial Dr, Cape Girardeau, MO £86 2 Oct - 3 Oct includes taxes & fees 9.6/10 Exceptional! (61 reviews) [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Comfort Suites Jackson-Cape Girardeau](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites Jackson-Cape Girardeau 2904 Old Orchard Rd, Jackson, MO £72 12 Oct - 13 Oct includes taxes & fees 8/10 Very Good! (733 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Allenville Hotels](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Benton Hotels](https://www.expedia.co.uk/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bertrand Hotels](https://www.expedia.co.uk/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Blodgett Hotels](https://www.expedia.co.uk/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Bloomsdale Hotels](https://www.expedia.co.uk/Bloomsdale-Hotels.d3000444549.Travel-Guide-Hotels) - [Adults Only Resorts & in Cape Girardeau](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Adults-Only-Resorts.0-0-d820-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Historic Hotels in Cape Girardeau](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Historic-Hotel.0-0-d820-tHistoricHotel.Travel-Guide-Filter-Hotels) - 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[Pilot Knob Holiday Rentals](https://www.expedia.co.uk/Pilot-Knob-Holiday-Rentals.d3000008143.Travel-Guide-HolidayRentals) - [Things to do in Southeast Missouri](https://www.expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) - [Book Hotels in Old Appleton on Expedia.com](https://www.expedia.com/Old-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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