Title: Hotels in Old Appleton, MO - Best Old Appleton Hotels from £49 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Old Appleton](https://expedia.co.uk/Old-Appleton-Holiday-Rentals.d553248634983492471.Travel-Guide-HolidayRentals)[Old Appleton Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Old-Appleton.d553248634983492471.Car-Hire-Guide)[Old Appleton Holidays](https://expedia.co.uk/Old-Appleton.d553248634983492471.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Old Appleton, MO from £49 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Old Appleton Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-01-10&d1=2026-01-10&endDate=2026-01-12&d2=2026-01-12&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-01-10&d1=2026-01-10&endDate=2026-01-12&d2=2026-01-12&lodging=APARTMENT) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-01-10&d1=2026-01-10&endDate=2026-01-12&d2=2026-01-12&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-01-10&d1=2026-01-10&endDate=2026-01-12&d2=2026-01-12&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Old+Appleton%2C+Missouri%2C+United+States+of+America®ionId=553248634983492471&latLong=37.597273%2C-89.712878&adults=2&startDate=2026-01-10&d1=2026-01-10&endDate=2026-01-12&d2=2026-01-12&amenities=PETS) ## Check prices for these dates Tonight [27 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983492471&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Dec - 29 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983492471&startDate=2025-12-28&endDate=2025-12-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983492471&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983492471&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Old Appleton hotels ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (104) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas £75 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/9a57fa49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau North [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Cape Girardeau 7.2/10 Good (686) "Overall was wonderful customer service and breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie £49 includes taxes & fees 8 Jan - 9 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (426) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie £51 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 9.0/10 Wonderful (677) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) GUY £67 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/bb7f277a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) Jackson 8.2/10 Very good (740) "Room was clean and affordable for one night. The morning person could have been more attentive to me being there for breakfast. No greeting at all and sat on her phone. I was the only one down in the breakfast area. Be more aware of her surroundings while working alone. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori £64 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) Jackson 9.6/10 Exceptional (1003) "Breakfast was great- staff was welcoming. Will stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura £65 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/668f3d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/c6e7fccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/d42a6e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG [](https://www.expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) Perryville 9.2/10 Wonderful (543) "lean, updated rooms, friendly staff and great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda £77 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/327c3e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/06b8cd59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Lofts [](https://www.expedia.co.uk/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) Perryville 9.2/10 Wonderful (17) "Great place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric [](https://www.expedia.co.uk/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/7f26b79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville [](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) Perryville 8.4/10 Very good (942) "Always a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven £56 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Desk, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/8b8e9c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/e7849830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/97771aac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville [](https://www.expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) Perryville 6.8/10 (415) "Was a nice place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lesliee £53 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/26f852d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/12e65c55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/082d2613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 [](https://www.expedia.co.uk/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) Perryville 6.6/10 (124) "Nice place would recommend Mary Jane’s if you’re looking for good food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £62 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-10&endDate=2026-01-11®ionId=553248634983492471&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOld-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOld-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels) ## Top Old Appleton Hotel Reviews ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Great location! Great staff well above and beyond. Will definitely stay again." [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "Hotel was very clean, quiet and has a great location! " [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg) ### Town House Inn 10/10 Excellent "Everything was excellent and comfortable beds " [](https://expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Notting Hill Cottage](https://images.trvl-media.com/lodging/49000000/49000000/48991900/48991852/9fab7427_y.jpg) ### Notting Hill Cottage 10/10 Excellent "The house was perfect for our needs! this is the third time we have stayed there, and it never disappoints!" [](https://expedia.co.uk/Alto-Pass-Hotels-Notting-Hill-Cottage.h48991852.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg) ### Super 8 by Wyndham Perryville 10/10 Excellent "The room and common area was very clean and attractive. But breakfast was a big disapp ointment. Maybe they ran out of bacon or sausage but it wasn't refilled so all of this left and 8:30 was waffles cereal and scrambled eggs." [](https://expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Beautiful location in the secluded woods ](https://images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/193ecf29_y.jpg) ### Beautiful location in the secluded woods 10/10 Excellent "Great host. Secluded location. Very nice house that was spotless." [](https://expedia.co.uk/Pomona-Hotels-Beautiful-Location-In-The-Secluded-Woods.h103080140.Hotel-Information) ![Hot Tub & Creek Views: Secluded Perryville Cabin](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/762b23c1_y.jpg) ### Hot Tub & Creek Views: Secluded Perryville Cabin 10/10 Excellent "We were celebrating a 50th birthday and a ladies reunion with life long friends. The location was perfect! Cell service and internet are spotty which made for a perfect unplugged get away. I wish the hot tub had been a little more secure to get in and out of...but at our ages we are extra careful lol Hoping to make this an annual trip! Just watch out for the walnuts!!! Lol" [](https://expedia.co.uk/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115013833.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4_y.jpg) ### Days Inn by Wyndham Perryville 10/10 Excellent "Clean " [](https://expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Gorgeous 1856 Log Cabin, Completely Renovated](https://images.trvl-media.com/lodging/113000000/112870000/112868700/112868642/673b3050_y.jpg) ### Gorgeous 1856 Log Cabin, Completely Renovated 10/10 Excellent "incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together." [](https://expedia.co.uk/Cape-Girardeau-Hotels-Gorgeous-1856-Log-Cabin.h112868642.Hotel-Information) ## More cheap stays in Old Appleton ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn 2011 North Kingshighway Cape Girardeau MO £49 8 Jan - 9 Jan 2026 includes taxes & fees 7/10 Good! (686 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Perryville 1500 Liberty Street Perryville MO £53 5 Jan - 6 Jan 2026 includes taxes & fees 6.8/10 (415 reviews) [](https://expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Perryville 1119 Vincent Dr Perryville MO £56 4 Jan - 5 Jan 2026 includes taxes & fees 8.4/10 Very Good! (941 reviews) [](https://expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Quality Inn Perryville I-55](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Perryville I-55 1517 S. Perryville Blvd. Perryville MO £62 29 Dec - 30 Dec includes taxes & fees 6.6/10 (124 reviews) [](https://expedia.co.uk/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Cape Girardeau 2520 Veterans Memorial Dr Cape Girardeau MO £75 4 Jan - 5 Jan 2026 includes taxes & fees 9.4/10 Exceptional! (103 reviews) [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St Perryville MO £77 1 Jan - 2 Jan 2026 includes taxes & fees 9.2/10 Wonderful! (543 reviews) [](https://expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Old Appleton? ### What are some of the best holiday rentals that Old Appleton has to offer? ### If I need to cancel my hotel reservation in Old Appleton, will I receive a refund? ### What is staying in Old Appleton like? ### What should I see while I'm in Old Appleton? ### What's the weather like in Old Appleton? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Allenville Hotels ](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Benton Hotels ](https://www.expedia.co.uk/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bertrand Hotels ](https://www.expedia.co.uk/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Blodgett Hotels ](https://www.expedia.co.uk/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Bloomsdale Hotels ](https://www.expedia.co.uk/Bloomsdale-Hotels.d3000444549.Travel-Guide-Hotels) - [Adults Only Resorts & in Cape Girardeau ](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Adults-Only-Resorts.0-0-d820-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Historic Hotels in Cape Girardeau ](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Historic-Hotel.0-0-d820-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Cape Girardeau Hotels ](https://www.expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Desloge Hotels ](https://www.expedia.co.uk/Desloge-Hotels.d55671.Travel-Guide-Hotels) - [Doe Run Hotels ](https://www.expedia.co.uk/Doe-Run-Hotels.d3000349343.Travel-Guide-Hotels) - [Farmington Hotels ](https://www.expedia.co.uk/Farmington-Hotels.d6058764.Travel-Guide-Hotels) - [Flat River Hotels ](https://www.expedia.co.uk/Flat-River-Hotels.d183474.Travel-Guide-Hotels) - [Fredericktown Hotels ](https://www.expedia.co.uk/Fredericktown-Hotels.d55114.Travel-Guide-Hotels) - [French Village Hotels ](https://www.expedia.co.uk/French-Village-Hotels.d553248635975849064.Travel-Guide-Hotels) - [Friedheim Hotels ](https://www.expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) - [Glen Allen Hotels ](https://www.expedia.co.uk/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Jackson Hotels ](https://www.expedia.co.uk/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Junction City Hotels ](https://www.expedia.co.uk/Junction-City-Hotels.d553248634983410095.Travel-Guide-Hotels) - [Marble Hill Hotels ](https://www.expedia.co.uk/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [Marquand Hotels ](https://www.expedia.co.uk/Marquand-Hotels.d553248634983260789.Travel-Guide-Hotels) - [Miner Hotels ](https://www.expedia.co.uk/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels) - [New Offenburg Hotels ](https://www.expedia.co.uk/New-Offenburg-Hotels.d3000349478.Travel-Guide-Hotels) - [Oran Hotels ](https://www.expedia.co.uk/Oran-Hotels.d3000445386.Travel-Guide-Hotels) - [Park Hills Hotels ](https://www.expedia.co.uk/Park-Hills-Hotels.d183485.Travel-Guide-Hotels) - [Perryville Hotels ](https://www.expedia.co.uk/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Sedgewickville Hotels ](https://www.expedia.co.uk/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Sikeston ](https://www.expedia.co.uk/Sikeston-Hotels-Gay-Friendly-Hotel.0-0-d6058766-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Sikeston ](https://www.expedia.co.uk/Sikeston-Hotels-Hotels-With-Indoor-Pools.0-0-d6058766-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Resorts in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotel-Resorts.d6058763-aaHotelResorts.Travel-Guide-Accommodation) - [Golf Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Golf-Hotels.0-0-d6058763-tGolfHotels.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotel-With-Connecting-Rooms.0-0-d6058763-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotels-With-Smoking-Rooms.0-0-d6058763-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-La-Quinta-Inn-Suites.0-0-d6058763--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Luxury-Hotel.0-0-d6058763-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Pet-Friendly-Hotel.0-0-d6058763-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Romantic-Hotel.0-0-d6058763-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Spa-Hotels.0-0-d6058763-tSpaHotels.Travel-Guide-Filter-Hotels) - [Southeast Missouri Hotels ](https://www.expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels) - [Hotels near Southeast Missouri State University ](https://www.expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [St Mary Hotels ](https://www.expedia.co.uk/St-Mary-Hotels.d3000445480.Travel-Guide-Hotels) - [Ste Genevieve Hotels ](https://www.expedia.co.uk/Ste-Genevieve-Hotels.d183502.Travel-Guide-Hotels) - [Valles Mines Hotels ](https://www.expedia.co.uk/Valles-Mines-Hotels.d3000349575.Travel-Guide-Hotels) - [Weingarten Hotels ](https://www.expedia.co.uk/Weingarten-Hotels.d553248635975847364.Travel-Guide-Hotels) - [Flights to Bonne Terre ](https://www.expedia.co.uk/Cheap-Flights-To-Bonne-Terre.d55598.Travel-Guide-Flights) - [Flights to Cape Girardeau ](https://www.expedia.co.uk/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights) - [Flights to Desloge ](https://www.expedia.co.uk/Cheap-Flights-To-Desloge.d55671.Travel-Guide-Flights) - [Flights to Park Hills ](https://www.expedia.co.uk/Cheap-Flights-To-Park-Hills.d183485.Travel-Guide-Flights) - [Flights to Wappapello ](https://www.expedia.co.uk/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights) - [Flights from Cape Girardeau Municipal ](https://www.expedia.co.uk/lp/airports/cgi/flights-from-cape-girardeau-municipal-airport) - [Flights from Sikeston Memorial Municipal ](https://www.expedia.co.uk/lp/airports/sik/flights-from-sikeston-memorial-municipal-airport) - [Flights from Park Hills ](https://www.expedia.co.uk/lp/flights/183485/flights-from-park-hills) - [Flights from Ste Genevieve ](https://www.expedia.co.uk/lp/flights/183502/flights-from-ste-genevieve) - [Flights from Pilot Knob ](https://www.expedia.co.uk/lp/flights/3000008143/flights-from-pilot-knob) - [Flights from Bertrand ](https://www.expedia.co.uk/lp/flights/3000349285/flights-from-bertrand) - [Flights from Doe Run ](https://www.expedia.co.uk/lp/flights/3000349343/flights-from-doe-run) - [Flights from Fredericktown ](https://www.expedia.co.uk/lp/flights/55114/flights-from-fredericktown) - [Flights from Marquand ](https://www.expedia.co.uk/lp/flights/553248634983260789/flights-from-marquand) - [Flights from Altenburg ](https://www.expedia.co.uk/lp/flights/553248634983289075/flights-from-altenburg) - [Flights from Zalma ](https://www.expedia.co.uk/lp/flights/553248634983373716/flights-from-zalma) - [Flights from Frohna ](https://www.expedia.co.uk/lp/flights/553248634983521632/flights-from-frohna) - [Flights from Wyatt ](https://www.expedia.co.uk/lp/flights/553248634983534991/flights-from-wyatt) - [Flights from Scott City ](https://www.expedia.co.uk/lp/flights/553248634983544376/flights-from-scott-city) - [Flights from Bonne Terre ](https://www.expedia.co.uk/lp/flights/55598/flights-from-bonne-terre) - [Flights from Jackson ](https://www.expedia.co.uk/lp/flights/55765/flights-from-jackson) - [Flights from Farmington ](https://www.expedia.co.uk/lp/flights/6058764/flights-from-farmington) - [Flights from Sikeston ](https://www.expedia.co.uk/lp/flights/6058766/flights-from-sikeston) - [Flights from Arcadia ](https://www.expedia.co.uk/lp/flights/6346857/flights-from-arcadia) - [Flights from Cape Girardeau ](https://www.expedia.co.uk/lp/flights/820/flights-from-cape-girardeau) - [Flights from Atlanta (ATL) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/atl/cgi/atlanta-to-cape-girardeau) - [Flights from Birmingham (BHM) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/bhm/cgi/birmingham-to-cape-girardeau) - [Flights from Mumbai (BOM) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/bom/cgi/mumbai-to-cape-girardeau) - [Flights from Sedalia (DMO) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/dmo/cgi/sedalia-to-cape-girardeau) - [Flights from Dublin (DUB) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/dub/cgi/dublin-to-cape-girardeau) - [Flights from New York (JFK) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/jfk/cgi/new-york-to-cape-girardeau) - [Flights from London (LHR) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/lhr/cgi/london-to-cape-girardeau) - [Flights from Lewiston (LWS) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/lws/cgi/lewiston-to-cape-girardeau) - [Flights from Chicago (MDW) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/mdw/cgi/chicago-to-cape-girardeau) - [Flights from Stow (MMN) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/mmn/cgi/stow-to-cape-girardeau) - [Flights from Pasco (PSC) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/psc/cgi/pasco-to-cape-girardeau) - [Flights from St. Louis (STL) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/stl/cgi/st-louis-to-cape-girardeau) - [Flights from Tijuana (TIJ) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/tij/cgi/tijuana-to-cape-girardeau) - [Visit Bonne Terre ](https://www.expedia.co.uk/Bonne-Terre.dx55598) - [Visit Farmington ](https://www.expedia.co.uk/Farmington.dx6058764) - [Visit Fredericktown ](https://www.expedia.co.uk/Fredericktown.dx55114) - [Leadwood Holidays ](https://www.expedia.co.uk/Leadwood.d3000349432.Holidays-City-Breaks) - [Sikeston Holidays ](https://www.expedia.co.uk/Sikeston.d6058766.Holidays-City-Breaks) - [Visit Sikeston ](https://www.expedia.co.uk/Sikeston.dx6058766) - [Visit Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri.dx6058763) - [Ste Genevieve Holidays ](https://www.expedia.co.uk/Ste-Genevieve.d183502.Holidays-City-Breaks) - [Ski Holiday Packages Southeast Missouri ](https://www.expedia.co.uk/lp/theme-holidays/ski-holidays/6058763/Southeast-Missouri) - [Rental cars Cape Girardeau Municipal airport ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau-Municipal.d6026978.Car-Hire-Guide) - [Car hire Cape Girardeau ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau.d820.Car-Hire-Guide) - [Car hire Ste Genevieve ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Ste-Genevieve.d183502.Car-Hire-Guide) - [Island Car Rentals Rental Cars in Cobalt ](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Cobalt.d553248634983153223-c1132.Car-Rental-Guide-Suppliers) - [Redspot Rental Cars in Oran ](https://www.expedia.co.uk/Redspot-Car-Rentals-In-Oran.d3000445386-c1078.Car-Rental-Guide-Suppliers) - [United Rental Cars in Southeast Missouri ](https://www.expedia.co.uk/United-Car-Rentals-In-Southeast-Missouri.d6058763-c1088.Car-Rental-Guide-Suppliers) - [Charleston Holiday Rentals ](https://www.expedia.co.uk/Charleston-Holiday-Rentals.d7182.Travel-Guide-HolidayRentals) - [Doe Run Holiday Rentals ](https://www.expedia.co.uk/Doe-Run-Holiday-Rentals.d3000349343.Travel-Guide-HolidayRentals) - [Pilot Knob Holiday Rentals ](https://www.expedia.co.uk/Pilot-Knob-Holiday-Rentals.d3000008143.Travel-Guide-HolidayRentals) - [Things to do in Southeast Missouri ](https://www.expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) - [Book Hotels in Old Appleton on Expedia.com ](https://www.expedia.com/Old-Appleton-Hotels.d553248634983492471.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app