Title: All Hotels by Small Luxury Hotels in Mediterranean Region - 2026 Updated Prices | Expedia.co.uk [Mediterranean Region Travel Guide](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide)[Mediterranean Region Holidays](https://expedia.co.uk/Mediterranean-Region.d844522342175883264.Holidays-City-Breaks) ![Mazarrón, Spain](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by Small Luxury Hotels in Mediterranean Region from £186 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [26 Dec - 27 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-12-26&endDate=2025-12-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mediterranean Region Small Luxury Hotels ![View from property](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/fa75df6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/358cbffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/16472e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Gallery (Colosseum View) | View from room](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/eed75016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Manfredi – Small Luxury Hotels of the World [](https://www.expedia.co.uk/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) Rome City Centre 9.0/10 Wonderful (641) "The rooftop restaurant for breakfast was amazing.. eat and enjoy the view of the coliseum, and archeological dig… Amazing food selection " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie £348 includes taxes & fees 14 Jan - 15 Jan 2026 [](https://www.expedia.co.uk/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) ![Suite (Babuino) | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/2b5bcf04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/a4520c11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/37c8bc67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/6ffc0628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Babuino 181 – Small Luxury Hotels of the World [](https://www.expedia.co.uk/Rome-Hotels-Babuino-181-Small-Luxury-Hotels-Of-The-World.h3483637.Hotel-Information) Rome City Centre 9.4/10 Exceptional (415) "great location, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) maura £186 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Rome-Hotels-Babuino-181-Small-Luxury-Hotels-Of-The-World.h3483637.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-09&endDate=2026-01-10®ionId=844522342175883264&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Small-Luxury-Hotels.0-0-d844522342175883264--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Small-Luxury-Hotels.0-0-d844522342175883264--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels) ## Top Mediterranean Region Hotel Reviews ![Arc la Rambla](https://images.trvl-media.com/lodging/1000000/570000/560400/560394/057df268_y.jpg) ### Arc la Rambla 10/10 Excellent "Very helpful staff, comfortable stay, excellent breafast and great location!!!" [](https://expedia.co.uk/Barcelona-Hotels-Arc-La-Rambla.h560394.Hotel-Information) ![Hotel Acta Moa- New Opening](https://images.trvl-media.com/lodging/118000000/117140000/117137400/117137301/1fd8b13a_y.jpg) ### Hotel Acta Moa- New Opening 10/10 Excellent "Excellent place end good staffs " [](https://expedia.co.uk/Lisbon-District-Hotels-Acta-Moa.h117137301.Hotel-Information) ![Hotel Regina](https://images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/e8709f28_y.jpg) ### Hotel Regina 10/10 Excellent "Yes, the room is kept and cleaned daily." [](https://expedia.co.uk/Madrid-Hotels-Hotel-Regina.h1170158.Hotel-Information) ![Hotel Dei Mellini](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/db6d1bc9_y.jpg) ### Hotel Dei Mellini 10/10 Excellent "Only complaint was someone had a barking dog in the room next to us. Other than that it was a great stay." [](https://expedia.co.uk/Rome-Hotels-Hotel-Dei-Mellini.h63399.Hotel-Information) ![Barcelona Airport Hotel](https://images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg) ### Barcelona Airport Hotel 10/10 Excellent "Good spread of breakfast. The front desk staff were helpful and friendly." [](https://expedia.co.uk/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Hard Rock Hotel Madrid](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f79da699_y.jpg) ### Hard Rock Hotel Madrid 10/10 Excellent "Great service " [](https://expedia.co.uk/Madrid-Hotels-Hard-Rock-Hotel-Madrid.h66906927.Hotel-Information) ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06_y.jpg) ### Hotel Quirinale 10/10 Excellent "Staff great. Wonderful hotel." [](https://expedia.co.uk/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Novotel Madrid Center](https://images.trvl-media.com/lodging/1000000/20000/17200/17125/ab11cb60_y.jpg) ### Novotel Madrid Center 10/10 Excellent "Great hotel" [](https://expedia.co.uk/Madrid-Hotels-Novotel-Madrid-Center.h17125.Hotel-Information) ![Latroupe Prado](https://images.trvl-media.com/lodging/93000000/92170000/92166200/92166187/b85212c1_y.jpg) ### Latroupe Prado 10/10 Excellent "Clean and quiet" [](https://expedia.co.uk/Madrid-Hotels-Latroupe-Madrid.h92166187.Hotel-Information)