Title: All Hotels by Small Luxury Hotels in Mediterranean Region - 2025 Updated Prices | Expedia.co.uk [Mediterranean Region Travel Guide](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide)[Mediterranean Region Holidays](https://expedia.co.uk/Mediterranean-Region.d844522342175883264.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/9/abc24df6f2e3266327aa8b559e87e79a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by Small Luxury Hotels in Mediterranean Region from £211 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [11 Nov - 12 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-11-11&endDate=2025-11-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Nov - 13 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-11-12&endDate=2025-11-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mediterranean Region Small Luxury Hotels Hotels ![Suite (Babuino) | 1 bedroom, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/2b5bcf04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/37c8bc67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | 1 bedroom, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/6ffc0628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | 1 bedroom, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/a4520c11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Babuino 181 – Small Luxury Hotels of the World Rome City Centre 9.4/10 Exceptional (409) "Hotel is lovely" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) roberta £211 includes taxes & fees 8 Dec - 9 Dec [](https://www.expedia.co.uk/Rome-Hotels-Babuino-181-Small-Luxury-Hotels-Of-The-World.h3483637.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/fa75df6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/16472e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Gallery (Colosseum View) | View from room](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/eed75016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/ca6626d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Manfredi – Small Luxury Hotels of the World Rome City Centre 9.0/10 Wonderful (631) "Wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reagan £366 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-25&endDate=2025-11-26®ionId=844522342175883264&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Small-Luxury-Hotels.0-0-d844522342175883264--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Small-Luxury-Hotels.0-0-d844522342175883264--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels) ## Top Mediterranean Region Hotel Reviews ![Hyatt Regency Barcelona Tower](//images.trvl-media.com/lodging/2000000/1340000/1338000/1337977/3f36a705_y.jpg) ### Hyatt Regency Barcelona Tower 10/10 Excellent "Beautiful hotel. Great staff" [](https://expedia.co.uk/Barcelona-Hotels-Hyatt-Regency-Barcelona-Tower.h1337977.Hotel-Information) ![Hard Rock Hotel Madrid](//images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f79da699_y.jpg) ### Hard Rock Hotel Madrid 10/10 Excellent "Loved it. Place was nice. Staff was professional and helpful. " [](https://expedia.co.uk/Madrid-Hotels-Hard-Rock-Hotel-Madrid.h66906927.Hotel-Information) ![Lamaro Hotel](//images.trvl-media.com/lodging/1000000/10000/3400/3388/a07cf64a_y.jpg) ### Lamaro Hotel 10/10 Excellent "Enjoyed this hotel and the rooftop bar a lot. It was so clean and quiet. Perfect stay in Barcelona. " [](https://expedia.co.uk/Barcelona-Hotels-Hotel-Colon-Barcelona.h3388.Hotel-Information) ![Arc la Rambla](//images.trvl-media.com/lodging/1000000/570000/560400/560394/057df268_y.jpg) ### Arc la Rambla 10/10 Excellent "Great location! Very clean, large room, comfortable beds." [](https://expedia.co.uk/Barcelona-Hotels-Arc-La-Rambla.h560394.Hotel-Information) ![Zleep Hotel Madrid Airport](//images.trvl-media.com/lodging/84000000/83330000/83323200/83323148/c45c31cc_y.jpg) ### Zleep Hotel Madrid Airport 10/10 Excellent "Excelente todo" [](https://expedia.co.uk/Madrid-Hotels-Zleep-Hotel-Madrid-Airport.h83323148.Hotel-Information) ![Hotel Riu Plaza España](//images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f_y.jpg) ### Hotel Riu Plaza España 10/10 Excellent "Espectacular muy buen servicio todo limpio y excelente ubicación " [](https://expedia.co.uk/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) ![Barcelona Airport Hotel](//images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg) ### Barcelona Airport Hotel 10/10 Excellent "Convenient, clean, model and spacious. Highly recommended. Shuttle late night and early morning. " [](https://expedia.co.uk/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![citizenM Rome Isola Tiberina](//images.trvl-media.com/lodging/95000000/94710000/94706900/94706900/2bd1dac3_y.jpg) ### citizenM Rome Isola Tiberina 10/10 Excellent "Cappuccino in the morning and a clean, quiet room. They allowed us an early check in too. " [](https://expedia.co.uk/Rome-Hotels-CitizenM-Rome-Isola-Tiberina.h94706900.Hotel-Information) ![Swandor Hotels & Resort Topkapi Palace - All Inclusive](//images.trvl-media.com/lodging/2000000/1280000/1271900/1271843/6ea3cfe9_y.jpg) ### Swandor Hotels & Resort Topkapi Palace - All Inclusive 10/10 Excellent "🙂" [](https://expedia.co.uk/Antalya-Hotels-Swandor-Hotels-Resort-Topkapi-Palace-All-Inclusive.h1271843.Hotel-Information)