Title: All Hotels by Small Luxury Hotels in Mediterranean Region - 2026 Updated Prices | Expedia.co.uk [Mediterranean Region Travel Guide](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide)[Mediterranean Region Holidays](https://expedia.co.uk/Mediterranean-Region.d844522342175883264.Holidays-City-Breaks) ![Mazarrón, Spain](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248633936349954/597750c4-7c4e-4a36-b33c-904705e647c4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [11 Feb - 12 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Feb - 13 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mediterranean Region Small Luxury Hotels ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/7d6d9ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/358cbffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/f163216b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Suite, 1 King Bed, Ground Floor (Colosseum View) | View from room](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/4d277572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Manfredi – Small Luxury Hotels of the World [](https://www.expedia.co.uk/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) Rome City Centre 9.0/10 Wonderful (647 reviews) "Absolutely loved this property. The location was perfect, room was spacious and comfortable. We loved ending our evenings in the court with a view of the Colosseum. Staff were friendly and helpful. Loved that it is a smaller property and felt cozy and like home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittney £347 includes taxes & fees 18 Feb - 19 Feb [](https://www.expedia.co.uk/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/4c316ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/2f87dbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room, Annex Building | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/5682d098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/830b3511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Babuino 181 – Small Luxury Hotels of the World [](https://www.expedia.co.uk/Rome-Hotels-Babuino-181-Small-Luxury-Hotels-Of-The-World.h3483637.Hotel-Information) Rome City Centre 9.4/10 Exceptional (419 reviews) "great location, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) maura £158 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Rome-Hotels-Babuino-181-Small-Luxury-Hotels-Of-The-World.h3483637.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-25&endDate=2026-02-26®ionId=844522342175883264&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Small-Luxury-Hotels.0-0-d844522342175883264--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Small-Luxury-Hotels.0-0-d844522342175883264--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels) ## Top Mediterranean Region Hotel Reviews ![Arc la Rambla](https://images.trvl-media.com/lodging/1000000/570000/560400/560394/057df268_y.jpg) ### Arc la Rambla 10/10 Excellent "Very helpful staff and a very good quality hotel " [](https://expedia.co.uk/Barcelona-Hotels-Arc-La-Rambla.h560394.Hotel-Information) ![Hard Rock Hotel Madrid](https://images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f79da699_y.jpg) ### Hard Rock Hotel Madrid 10/10 Excellent "My #1 option in Madrid. I have stayed 5 or 6 times. " [](https://expedia.co.uk/Madrid-Hotels-Hard-Rock-Hotel-Madrid.h66906927.Hotel-Information) ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06_y.jpg) ### Hotel Quirinale 10/10 Excellent "The hotel was great ! Spotlessly clean , lovely large room and bathroom . The breakfast was plentiful with a large selection of choice both hot and cold. We loved the location - just a stroll to the sights of the Coliseum and Trevi Fountain. A lovely stay in Rome! " [](https://expedia.co.uk/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Hotel Emperador](https://images.trvl-media.com/lodging/1000000/10000/1000/915/2f47a159_y.jpg) ### Hotel Emperador 10/10 Excellent "Clean rooms, friendly staff, and excellent location " [](https://expedia.co.uk/Madrid-Hotels-Hotel-Emperador.h915.Hotel-Information) ![Grand Hyatt Athens](https://images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f_y.jpg) ### Grand Hyatt Athens 10/10 Excellent "Nice staff, clean room, nice breakfast. " [](https://expedia.co.uk/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) ![Palais Moulay Said & SPA](https://images.trvl-media.com/lodging/112000000/111800000/111799600/111799505/b255f715_y.jpg) ### Palais Moulay Said & SPA 10/10 Excellent "Very good place" [](https://expedia.co.uk/Marrakech-Hotels-Riad-Moulay-Said-SPA.h111799505.Hotel-Information) ![Hotel Riu Plaza España](https://images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f_y.jpg) ### Hotel Riu Plaza España 10/10 Excellent "Everything was great. The only thing was a little crowded, the elevators and the breakfast. But the hotel’s location was excellent. " [](https://expedia.co.uk/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) ![Athens Gate Hotel](https://images.trvl-media.com/lodging/1000000/30000/22200/22143/2f328705_y.jpg) ### Athens Gate Hotel 10/10 Excellent "Spotless room, amazing staff and location." [](https://expedia.co.uk/Athens-Hotels-Athens-Gate-Hotel.h22143.Hotel-Information) ![Trastevere Roma | UNA Esperienze](https://images.trvl-media.com/lodging/75000000/74060000/74055900/74055827/0d267171_y.jpg) ### Trastevere Roma | UNA Esperienze 10/10 Excellent "Everything about our stay here was exceptional except for the restaurant upstairs. We had 1 meal here and it was the worst meal we had in Rome. There are restaurants all around this hotel." [](https://expedia.co.uk/Rome-Hotels-UNAHOTELS-Trastevere-Roma.h74055827.Hotel-Information)