Title: All Hotels by Small Luxury Hotels in Mediterranean Region - 2025 Updated Prices | Expedia.co.uk

  

[Mediterranean Region Travel Guide](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide)[Mediterranean Region Holidays](https://expedia.co.uk/Mediterranean-Region.d844522342175883264.Holidays-City-Breaks)

![](https://mediaim.expedia.com/destination/9/abc24df6f2e3266327aa8b559e87e79a.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Search Hotels by Small Luxury Hotels in Mediterranean Region from £428

![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg)

### 

Change your mind

Book hotels with free cancellation

![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)

### 

Treat yourself

Save instantly and earn perks with One Key

[Learn about One Key](https://www.expedia.co.uk/welcome-one-key)

![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)

### 

Be picky

Search almost a million properties worldwide

## Check prices for these dates

Tonight

[20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-09-20&endDate=2025-09-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-09-21&endDate=2025-09-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Mediterranean Region Small Luxury Hotels Hotels

## Our top choices for Mediterranean Region Small Luxury Hotels

![Suite (Babuino) | 1 bedroom, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/2b5bcf04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/37c8bc67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite | 1 bedroom, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/6ffc0628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3490000/3483700/3483637/aeeb8fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Babuino 181 – Small Luxury Hotels of the World

Rome City Centre

9.4/10

Exceptional

(399)

"Lovely, clean and great location. "

£428

includes taxes & fees

21 Sept - 22 Sept

[](https://www.expedia.co.uk/Rome-Hotels-Babuino-181-Small-Luxury-Hotels-Of-The-World.h3483637.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/fa75df6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/16472e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/ca6626d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/2000000/1070000/1065700/1065602/358cbffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palazzo Manfredi – Small Luxury Hotels of the World

Rome City Centre

9.0/10

Wonderful

(618)

"Beautiful hotel"

£556

includes taxes & fees

14 Oct - 15 Oct

[](https://www.expedia.co.uk/Rome-Hotels-Palazzo-Manfredi-Small-Luxury-Hotels-Of-The-World.h1065602.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-04&endDate=2025-10-05&regionId=844522342175883264&adults=2&sort=RECOMMENDED&openPlayBack=true)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Small-Luxury-Hotels.0-0-d844522342175883264--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Small-Luxury-Hotels.0-0-d844522342175883264--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels)

## Top Mediterranean Region Hotel Reviews

![Grand Hyatt Athens](//images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f_y.jpg)

### Grand Hyatt Athens

10/10 Excellent

"Friendly staff, clean rooms, great food options"

[](https://expedia.co.uk/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information)

![Hotel Regina](//images.trvl-media.com/lodging/2000000/1180000/1170200/1170158/559c033d_y.jpg)

### Hotel Regina

10/10 Excellent

"Beautiful hotel! Modern, clean and quiet. Across the street from the Four Seasons at half the price. You’ll love this hotel. "

[](https://expedia.co.uk/Madrid-Hotels-Hotel-Regina.h1170158.Hotel-Information)

![Grand Hyatt Barcelona](//images.trvl-media.com/lodging/1000000/20000/17400/17348/792b4779_y.jpg)

### Grand Hyatt Barcelona

10/10 Excellent

"Great property that is well maintained with attentive staff. The area is a ways off from the center though. Positive are that it's super quiet. Negatives are that there are limited dining options in the immediate vecinity."

[](https://expedia.co.uk/Barcelona-Hotels-Hotel-SOFIA-Barcelona.h17348.Hotel-Information)

![Corinthia Lisbon](//images.trvl-media.com/lodging/1000000/10000/4100/4014/b31c4e2f_y.jpg)

### Corinthia Lisbon

10/10 Excellent

"Great service and beautiful property."

[](https://expedia.co.uk/Lisbon-District-Hotels-Corinthia-Lisbon.h4014.Hotel-Information)

![Hotel Riu Plaza España](//images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f_y.jpg)

### Hotel Riu Plaza España

10/10 Excellent

"This hotel is at the center of Madrid perfect location, close to everything, lots of dining options and the staff was super friendly- Luis was super fun my fellow Dominican, kitchen staff very professional as well and attentive. Will be back for sure! "

[](https://expedia.co.uk/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information)

![INNSiDE by Melia Barcelona Apolo](//images.trvl-media.com/lodging/1000000/70000/68700/68689/81eaf4dd_y.jpg)

### INNSiDE by Melia Barcelona Apolo

10/10 Excellent

"Very central to everything including tours"

[](https://expedia.co.uk/Barcelona-Hotels-Hotel-Barcelona-Apolo.h68689.Hotel-Information)

![Senator Barajas Hotel](//images.trvl-media.com/lodging/1000000/20000/17300/17281/9a9d4c37_y.jpg)

### Senator Barajas Hotel

10/10 Excellent

"The staff was very nice"

[](https://expedia.co.uk/Madrid-Hotels-Senator-Barajas.h17281.Hotel-Information)

![Akra Antalya](//images.trvl-media.com/lodging/1000000/30000/21700/21663/1add5596_y.jpg)

### Akra Antalya

10/10 Excellent

"Really a very good place"

[](https://expedia.co.uk/Antalya-Hotels-Akra-Hotel.h21663.Hotel-Information)

![iQ Hotel Roma](//images.trvl-media.com/lodging/4000000/3550000/3546400/3546384/5d733e75_y.jpg)

### iQ Hotel Roma

10/10 Excellent

"Overall very good. Staff was very helpful with booking taxi on our checkout at 3am since our flight was at 6 am so no trains. Bathroom shower was a bit small but ok. Close to Train station. Walkable to Trevi fountain and Colosseum. Pretty good restaurant on the rooftop. Mini fridge with free drinks and small snacks which were great after roaming around in hot weather. Would stay again. "

[](https://expedia.co.uk/Rome-Hotels-IQ-Hotel-Roma.h3546384.Hotel-Information)