Title: All Hotels by Relais & Chateaux in Mediterranean Region - 2025 Updated Prices | Expedia.co.uk [Mediterranean Region Travel Guide](https://expedia.co.uk/Mediterranean-Region.dx844522342175883264)[Hotels in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Hotels.d844522342175883264.Travel-Guide-Hotels)[Holiday Rentals in Mediterranean Region](https://expedia.co.uk/Mediterranean-Region-Holiday-Rentals.d844522342175883264.Travel-Guide-HolidayRentals)[Flights to Mediterranean Region](https://expedia.co.uk/Cheap-Flights-To-Mediterranean-Region.d844522342175883264.Travel-Guide-Flights)[Mediterranean Region Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mediterranean-Region.d844522342175883264.Car-Hire-Guide)[Mediterranean Region Holidays](https://expedia.co.uk/Mediterranean-Region.d844522342175883264.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/9/abc24df6f2e3266327aa8b559e87e79a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by Relais & Chateaux in Mediterranean Region from £253 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=844522342175883264&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mediterranean Region Relais & Chateaux Hotels ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/372ab6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/e2ae3d67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7064e389.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/10000/3700/3654/7604df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Raphaël – Relais & Châteaux Rome City Centre 9.2/10 Wonderful (1001) "Staff was amazing, Harp player at breakfast was wonderful. And the food choices was so good!" £253 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Rome-Hotels-Bio-Hotel-Raphael-Relais-Chateaux.h3654.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=844522342175883264&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Relais-Chateaux.0-0-d844522342175883264--bRelaisChateaux.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMediterranean-Region-Hotels-Relais-Chateaux.0-0-d844522342175883264--bRelaisChateaux.Travel-Guide-Filter-Hotels) ## Top Mediterranean Region Hotel Reviews ![Hotel Quirinale](//images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06_y.jpg) ### Hotel Quirinale 10/10 Excellent "Fantastic stay, centrally located with every amenity. " [](https://expedia.co.uk/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Barcelona Airport Hotel](//images.trvl-media.com/lodging/2000000/1440000/1440000/1439964/ab2f831e_y.jpg) ### Barcelona Airport Hotel 10/10 Excellent "Very convenient airport shuttle. Restaurant opens until 1:00 am to accommodate late check-in. Complimentary mini bar. Very tasty breakfast with great selection of fresh fruits." [](https://expedia.co.uk/Barcelona-Hotels-Barcelona-Airport-Hotel.h1439964.Hotel-Information) ![Hard Rock Hotel Madrid](//images.trvl-media.com/lodging/67000000/66910000/66907000/66906927/f79da699_y.jpg) ### Hard Rock Hotel Madrid 10/10 Excellent "Great staff and very clean. My only complaint was I couldn't get the shower gel out of the bottle!!" [](https://expedia.co.uk/Madrid-Hotels-Hard-Rock-Hotel-Madrid.h66906927.Hotel-Information) ![Napoleon Hotel](//images.trvl-media.com/lodging/1000000/10000/6600/6548/9e2b5c71_y.jpg) ### Napoleon Hotel 10/10 Excellent "Jane at front desk was very helpful and and shuttle was convenient and professional " [](https://expedia.co.uk/Rome-Hotels-Napoleon-Hotel.h6548.Hotel-Information) ![Andante Hotel](//images.trvl-media.com/lodging/5000000/4870000/4868200/4868126/0651d54b_y.jpg) ### Andante Hotel 10/10 Excellent "Two things that I am not completely happy with: 1. No coffee pot in my room. 2. The neighborhood is a bit mixed, but very safe, as there are a lot of police. Otherwise I would have given 5 stars." [](https://expedia.co.uk/Barcelona-Hotels-Andante-Hotel.h4868126.Hotel-Information) ![Grand Hyatt Athens](//images.trvl-media.com/lodging/1000000/30000/21100/21031/dbfe795f_y.jpg) ### Grand Hyatt Athens 10/10 Excellent "Clean rooms " [](https://expedia.co.uk/Athens-Hotels-Grand-Hyatt-Athens.h21031.Hotel-Information) ![Hotel Riu Plaza España](//images.trvl-media.com/lodging/30000000/29350000/29345500/29345493/42fcab3f_y.jpg) ### Hotel Riu Plaza España 10/10 Excellent "Great location. Friendly staff. Easy check inn and out " [](https://expedia.co.uk/Madrid-Hotels-Hotel-Riu-Plaza-Espana.h29345493.Hotel-Information) ![Latroupe Prado](//images.trvl-media.com/lodging/93000000/92170000/92166200/92166187/b85212c1_y.jpg) ### Latroupe Prado 10/10 Excellent "Everything was great except breakfast, was horrible." [](https://expedia.co.uk/Madrid-Hotels-Latroupe-Madrid.h92166187.Hotel-Information) ![Royal Ramblas](//images.trvl-media.com/lodging/1000000/10000/5500/5469/c09b05ed_y.jpg) ### Royal Ramblas 10/10 Excellent "Firts of all we came to the hotel at 10:00am. And the girl was able to provide us a room. Sadly i forgot her name, but we really apreciate this comodity. Desk people always helpful. At the time of leaving we left the hotel at 7:00am, and Hector was able to set up a picnick breakfast before leaving. That we really apreciate. Rooms always clean and towels changed every day. Those Dominican Rep ladies are excellent. Hotel clean, very modern and comfortable. Bed mattress also god. And enoght space to keep your belongins ready to use. In the rigth place if coming from the airtport and take the aerobus. Next to the plaza catalunya to go every where with metro. Great restaurants and atractions near. " [](https://expedia.co.uk/Barcelona-Hotels-Royal-Ramblas.h5469.Hotel-Information)