A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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4 Oct - 5 Oct
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Our top choices for Mcleod Regional Medical Center hotels

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

1. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
0.4 mi from Mcleod Regional Medical Center
United States
Ivette
£85
includes taxes & fees
12 Oct - 13 Oct
Hyatt Place Florence Downtown
A restaurant with brick walls, framed awards, and a bar area.
A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.
A bar area with a curved counter, multiple stools, and a brick wall backdrop.
A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

2. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
0.5 mi from Mcleod Regional Medical Center
United States
Ankh
£102
includes taxes & fees
1 Nov - 2 Nov
Hotel Florence, Tapestry Collection by Hilton
A sign for the Rodeway Inn.

3. Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
0.7 mi from Mcleod Regional Medical Center
United States
F
£37
includes taxes & fees
2 Nov - 3 Nov
Rodeway Inn Florence Downtown
A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.
A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.
A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.
A modern kitchen with grey cabinets, stainless steel appliances, and bar stools.

4. The Urban Flats

The Urban Flats
0.5 mi from Mcleod Regional Medical Center
£326
includes taxes & fees
14 Oct - 15 Oct
The Urban Flats
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

5. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
3.4 mi from Mcleod Regional Medical Center
United States
Windia
£76
includes taxes & fees
11 Oct - 12 Oct
Park Inn by Radisson Florence, SC
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A hotel pool area with two pools, a lifeguard stand, and a towel service station.
A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.
A coffee station with two coffee machines and a display of coffee pods and cups.

6. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
5 mi from Mcleod Regional Medical Center
United States
Leigh
£96
includes taxes & fees
11 Oct - 12 Oct
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel lobby with a reception desk, seating area, and a television screen.
A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

7. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
4.3 mi from Mcleod Regional Medical Center
United States
Mila
£86
includes taxes & fees
25 Oct - 26 Oct
Comfort Inn & Suites Florence Center Area
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

8. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
3.4 mi from Mcleod Regional Medical Center
United States
HOMERO
£55
includes taxes & fees
5 Oct - 6 Oct
Howard Johnson by Wyndham Florence
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
A corridor with shelves stocked with snacks and a frozen food display.

9. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
3.6 mi from Mcleod Regional Medical Center
United States
Ashokraju
£104
includes taxes & fees
7 Oct - 8 Oct
Hampton Inn & Suites Florence-North-I-95
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
An outdoor kitchen area with a grill, a pool, and a covered seating area.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.
A conference room with round tables, chairs, and a carpeted floor.

10. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
5 mi from Mcleod Regional Medical Center
United States
Tishia
£121
includes taxes & fees
18 Oct - 19 Oct
Staybridge Suites Florence - Civic Center by IHG
A hotel entrance with a stone facade, glass doors, and a number '501' above.
A corner market with shelves stocked with snacks and beverages, and two large refrigerators.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

11. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
4.3 mi from Mcleod Regional Medical Center
United States
Felecia
£100
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott Florence I-20
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.
A modern lounge area with seating, tables, and a pool table.
A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

12. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
3.7 mi from Mcleod Regional Medical Center
United States
Tiffany
£90
includes taxes & fees
11 Oct - 12 Oct
Tru by Hilton Florence I-95
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern lounge area with a sofa, armchairs, and small tables.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.
A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

13. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
4.3 mi from Mcleod Regional Medical Center
United States
Crystal
£96
includes taxes & fees
1 Nov - 2 Nov
TownePlace Suites by Marriott Florence
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.
A hotel with a modern design, featuring a prominent sign for the 'Country Inn & Suites by Radisson.'
A modern cafeteria with long wooden tables, green chairs, and yellow accents.

14. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
3.4 mi from Mcleod Regional Medical Center
United States
Tienia
£74
includes taxes & fees
18 Oct - 19 Oct
Spark by Hilton Florence North I-95, SC
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A hotel with a modern design, featuring multiple floors and a parking lot.
A modern hotel lobby with a fireplace, seating area, and a reception desk.
A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.

15. Residence Inn Marriott Florence

Residence Inn Marriott Florence
4.5 mi from Mcleod Regional Medical Center
United States
TERRENCE
£94
includes taxes & fees
1 Nov - 2 Nov
Residence Inn Marriott Florence
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
An outdoor patio area with brick walls, a fire pit, and outdoor seating.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

16. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
5.7 mi from Mcleod Regional Medical Center
United States
Christopher
£111
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A spacious lobby with a reception desk, seating area, and large windows.
An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.
A spacious lobby with a large fireplace, comfortable seating, and potted plants.
A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

17. Hilton Garden Inn Florence

Hilton Garden Inn Florence
4.5 mi from Mcleod Regional Medical Center
United States
Derrick
£100
includes taxes & fees
11 Oct - 12 Oct
Hilton Garden Inn Florence
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
A modern coffee station with a counter, coffee machines, and a seating area with chairs.
A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.

18. Comfort Suites Florence I-95

Comfort Suites Florence I-95
3.6 mi from Mcleod Regional Medical Center
United States
Denise
£75
includes taxes & fees
25 Oct - 26 Oct
Comfort Suites Florence I-95
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A lobby with a fireplace, seating area, and a television.
A hotel lobby with a reception desk, seating area, and a welcome mat.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

19. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
4.5 mi from Mcleod Regional Medical Center
United States
Ryan
£96
includes taxes & fees
11 Oct - 12 Oct
Hampton Inn & Suites Florence Center
A hotel room with a desk, chair, bed, and a yellow sofa.
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

20. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
4.7 mi from Mcleod Regional Medical Center
Canada
Noémie
£75
includes taxes & fees
18 Oct - 19 Oct
Quality Inn & Suites Florence Civic Center
View all properties

Top Mcleod Regional Medical Center Hotel Reviews

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent
"Edward was amazing helping straighten out an issue with my Expedia booking"
Cynthia 1-night trip
Posted 14 hours ago
Spark by Hilton Florence North I-95, SC
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

8/10 Good
"The room was clean and it was a peaceful and quiet night of sleep. I appreciated the comfy bed and pillows. The air took awhile to actually cool the room off but it got cold after awhile (1+ hours). The breakfast was disappointing as the non-bread options were not replenished. I understand this at 9:55am. Not at 9.20am. The staff seemed annoyed to answer questions about the lack of breakfast food options or if they were being replenished."
Leah 1-night trip
Posted 2 days ago
Park Inn by Radisson Florence, SC
Best Western Inn

Best Western Inn

10/10 Excellent
"Clean rooms and friendly staff and great breakfast"
Steward Heikes 1-night trip
Posted 7 days ago
Best Western Inn
Pineapple House: Historic. Southern Charm. Walk Downtown.

Pineapple House: Historic. Southern Charm. Walk Downtown.

10/10 Excellent
"Absolutely beautiful home in a quiet, safe neighborhood. It had everything I needed for an incredible stay. Excellent water pressure in shower. Comfortable bed, beautiful decor, snacks, water, and communication with owner was excellent. Easy check in and check out. Thank you for your hospitality and for being so welcoming during my stay. This is THE place to stay in Florence, SC. Thank you again. I will return in the future."
Leanna F. 3-night trip
Posted 3 weeks ago
Pineapple House: Historic. Southern Charm. Walk Downtown.
Come Stay A While

Come Stay A While

10/10 Excellent
"Loved the in unit washer and dryer. The house was visibly clean and smelled clean. Plenty of towels. The kitchen had cutting boards and pots and pans. Very comfortable and nice neighborhood. Host was very responsive."
Anndria C. 14-night trip
Posted 3 months ago
Come Stay A While

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?
Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 18 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Mcleod Regional Medical Center?
Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.
How many hotels can I expect to find near Mcleod Regional Medical Center?
Expedia has 18 hotels and other accommodation options within a mile from Mcleod Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals close to Mcleod Regional Medical Center.
What can I see and do near Mcleod Regional Medical Center?
You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.