Title: The Best Hotels Closest to Mayo Clinic Health System in Lake City - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Lake City](https://expedia.co.uk/Lake-City-Holiday-Rentals.d123282.Travel-Guide-HolidayRentals)[Mayo Clinic Health System Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mayo-Clinic-Health-System.d624554369980018688.Car-Hire-Guide)[Mayo Clinic Health System Holidays](https://expedia.co.uk/Mayo-Clinic-Health-System-Lake-City.d624554369980018688.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [10 Feb - 11 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624554369980018688&startDate=2026-02-10&endDate=2026-02-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Feb - 12 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624554369980018688&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624554369980018688&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624554369980018688&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Mayo Clinic Health System hotels ![Indoor pool](https://images.trvl-media.com/lodging/1000000/910000/905800/905781/0815a82d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/910000/905800/905781/339049a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/910000/905800/905781/93bb801e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/910000/905800/905781/16288ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Lake City [](https://www.expedia.co.uk/Red-Wing-Hotels-AmericInn-By-Wyndham-Lake-City.h905781.Hotel-Information) 0.2 mi from Mayo Clinic Health System 9.0/10 Wonderful (647 reviews) "Wonderful stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alan £79 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Red-Wing-Hotels-AmericInn-By-Wyndham-Lake-City.h905781.Hotel-Information) ![Condo, 3 Bedrooms, Pool Access, Lake View | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/78000000/77970000/77960400/77960311/ec7db4bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/78000000/77970000/77960400/77960311/2d10de2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 3 Bedrooms, Pool Access, Lake View | In-room dining](https://images.trvl-media.com/lodging/78000000/77970000/77960400/77960311/cc34b1d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/78000000/77970000/77960400/77960311/03de0295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunset Motel [](https://www.expedia.co.uk/Lake-City-Hotels-Sunset-Motel.h77960311.Hotel-Information) 0.2 mi from Mayo Clinic Health System 9.0/10 Wonderful (161 reviews) "Sunset Motel exceeded my expectations! The property is clean with a great view of the lake just across the street. Check in is a breeze and staff is very communicative. Highly recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Abby £83 includes taxes & fees 13 Feb - 14 Feb [](https://www.expedia.co.uk/Lake-City-Hotels-Sunset-Motel.h77960311.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/d54840be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/df1235ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/e1720891.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Single Room | Individually decorated, individually furnished, desk, soundproofing](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/e51df0cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Round Barn Farm B & B Event Center [](https://www.expedia.co.uk/Red-Wing-Hotels-Round-Barn-Farm-B-B-Event-Center.h46980893.Hotel-Information) 10.4 mi from Mayo Clinic Health System 10/10 Exceptional (40 reviews) "Beautiful property with great hosts! Strongly recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Austin [](https://www.expedia.co.uk/Red-Wing-Hotels-Round-Barn-Farm-B-B-Event-Center.h46980893.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25®ionId=624554369980018688&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Mayo Clinic Health System Hotel Reviews ![Sunset Motel](https://images.trvl-media.com/lodging/78000000/77970000/77960400/77960311/03de0295_y.jpg) ### Sunset Motel 10/10 Excellent "Glad they added a plug in for phone charger. Touch lamps. Easy check in check out ststem" [](https://expedia.co.uk/Lake-City-Hotels-Sunset-Motel.h77960311.Hotel-Information) ![St James Hotel, a Historic Hotel of America](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/c90b9231_y.jpg) ### St James Hotel, a Historic Hotel of America 10/10 Excellent "The room and linens were pristine. Front desk staff were available and helpful. The hotel food was very good. A lovely small town " [](https://expedia.co.uk/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![Vacation rental or event venue on Lake Pepin](https://images.trvl-media.com/lodging/60000000/59010000/59003200/59003187/b4e43d2c_y.jpg) ### Vacation rental or event venue on Lake Pepin 10/10 Excellent "Deb is great and the property is fantastic. I absolutely love coming to the Maiden Rock Retreat. Everything is nice and clean and it's a great experience. Thank you for everything, Deb!" [](https://expedia.co.uk/Maiden-Rock-Hotels-Vacation-Rental-Or-Event-Venue-On-Lake-Pepin.h59003187.Hotel-Information) ![The Alton House - Come experience tiny house living in beautiful Pepin!](https://images.trvl-media.com/lodging/108000000/107320000/107318700/107318679/eb859c47_y.jpg) ### The Alton House - Come experience tiny house living in beautiful Pepin! 10/10 Excellent "Adorable tiny home! We had everything we needed for a two night stay, including the most comfortable bed. Excellent location for the wedding we attended. Appreciate the prompt communication and ease of check in/check out process. We look forward to coming back to Pepin in warmer weather and will not hesitate to book this home again! " [](https://expedia.co.uk/Pepin-Hotels-The-Alton-House-Come-Experience-Tiny-House-Living-In-Beautiful-Pepin.h107318679.Hotel-Information) ![AmericInn by Wyndham Lake City](https://images.trvl-media.com/lodging/1000000/910000/905800/905781/0815a82d_y.jpg) ### AmericInn by Wyndham Lake City 10/10 Excellent "Clean. Upgraded room for no extra charge! Cleanliness was Superior all the way around with the pool and the room and the hallways and the breakfast area!" [](https://expedia.co.uk/Red-Wing-Hotels-AmericInn-By-Wyndham-Lake-City.h905781.Hotel-Information) ![NEW Build Home with Indoor Oasis | Game Room | Bunkroom](https://images.trvl-media.com/lodging/118000000/117470000/117466400/117466334/ed117ebd_y.jpg) ### NEW Build Home with Indoor Oasis | Game Room | Bunkroom 10/10 Excellent "Yes they did and we had everything we needed " [](https://expedia.co.uk/Wabasha-Hotels-NEW-Build-Home-With-Outdoor-Oasis-Game-Room-Bunkroom.h117466334.Hotel-Information) ![40 Acre Wooded Retreat Overlooking Lake Pepin with Lakefront](https://images.trvl-media.com/lodging/20000000/19400000/19392800/19392720/015d7c18_y.jpg) ### 40 Acre Wooded Retreat Overlooking Lake Pepin with Lakefront 10/10 Excellent "Beautiful, large cabin overlooking Lake Pepin! Kitchen was well stocked with everything we needed to cook for a group of 8 moms. Beds were super comfortable, but more open sleeping arrangements without a ton of privacy unless you were in the downstairs bedroom. Lots of towels, cleaning supplies. We did not use the hot tub, but great option for guests. Hope to stay again in the future!" [](https://expedia.co.uk/Maiden-Rock-Hotels-40-Acre-Wooded-Retreat-Overlooking-Lake-Pepin-With-Lakefront.h19392720.Hotel-Information) ![Peace of Pepin 3BR house with 2nd Story Hot Tub and Across from Public Beach](https://images.trvl-media.com/lodging/112000000/111810000/111807200/111807149/b2727cbe_y.jpg) ### Peace of Pepin 3BR house with 2nd Story Hot Tub and Across from Public Beach 10/10 Excellent "Great house. Everything you need!" [](https://expedia.co.uk/Pepin-Hotels-Charming-3-Bedroom-House-With-2nd-Story-Hot-Tub-And-Across-From-Public-Beach.h111807149.Hotel-Information) ![Scenic, waterfront home on Lake Pepin with HOT TUB](https://images.trvl-media.com/lodging/92000000/91140000/91136600/91136600/3fba91cb_y.jpg) ### Scenic, waterfront home on Lake Pepin with HOT TUB 10/10 Excellent "Everything was flawless. Best stocked kitchen I’ve ever seen. Comfy afghans, lovely surroundings without all that kitsch. Hot tub beyond compare… somebody stop me" [](https://expedia.co.uk/Pepin-Hotels-Scenic.h91136600.Hotel-Information) ## Hotels near other Mayo Clinic Health System attractions ### North End Park North End Park is just one of the places to see in Lake City, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the lakeside. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=920054647470092288) ### Lake City Golf Enjoy a round of golf in Lake City at Lake City Golf. While you're in the area, stroll along the lakeside. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=920055675867033600) ### Gold Star Mothers Park After visiting Gold Star Mothers Park, make a plan to see the other sights and activities in Lake City. While you're in the area, stroll along the lakeside. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=920055491967950848) ### Hok-Si-La Park Explore the great outdoors at Hok-Si-La Park, a lovely green space in Lake City. While you're in the area, stroll along the lakeside. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=915525954867195904) ### McCahill Ball Field McCahill Ball Field is just one of the places to see in Lake City, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the lakeside. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=920054794797129728) ### Underwood Park & Fields After visiting Underwood Park & Fields, make a plan to see the other sights and activities in Lake City. While you're in the area, stroll along the lakeside. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=920054444123942912) ### Ohuta Park Ohuta Park is just one of the places to see in Lake City, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the lakeside. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=920054626515349504) ### The Jewel Golf Club Enjoy a round of golf in Lake City at The Jewel Golf Club. While you're in the area, stroll along the lakeside. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=920055663584223232) ## Frequently asked questions ### What's the area like around Mayo Clinic Health System? ### Where is the best place to stay close to Mayo Clinic Health System? ### How many hotels are there close to Mayo Clinic Health System? ### If I need to cancel the hotel reservation for my stay near Mayo Clinic Health System, will I receive a refund? ### What can I see and do near Mayo Clinic Health System?