The Best Hotels Closest to Mark Twain Boyhood Home and Museum in Hannibal - 2026 Updated Prices

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Our top choices for Mark Twain Boyhood Home and Museum hotels

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A compact kitchen with a refrigerator, microwave, and sink.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

1. Riverside Inn Hannibal

0.1 mi from Mark Twain Boyhood Home and Museum

Jack

£158

includes taxes & fees

30 Sept - 1 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

2. Best Western On The River

< 0.1 mi from Mark Twain Boyhood Home and Museum

Raymond

£96

includes taxes & fees

5 Oct - 6 Oct

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

3. Lighthouse Inn & Suites

0.4 mi from Mark Twain Boyhood Home and Museum

Kari

£147

includes taxes & fees

30 Sept - 1 Oct

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A large, two-story house with a porch and a sign indicating 'ONE WAY'.

A fireplace with decorative elements, framed pictures, and a vase of red flowers.

A dining area with a table set for four, surrounded by wooden chairs. A chandelier hangs above the table, and a lamp provides additional lighting.

4. Garden House Bed and Breakfast

0.2 mi from Mark Twain Boyhood Home and Museum

Edward

£68

includes taxes & fees

7 Oct - 8 Oct

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A hotel room with two beds, a window with red curtains, an air conditioning unit, and two bedside lamps.

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."

5. Motel 6 Hannibal, MO

1.8 mi from Mark Twain Boyhood Home and Museum

Donna B

£50

includes taxes & fees

8 Oct - 9 Oct

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted artwork.

A patio with red Adirondack chairs and a table, surrounded by a pebble border.

6. Super 8 by Wyndham Hannibal

1.9 mi from Mark Twain Boyhood Home and Museum

Betty

£54

includes taxes & fees

29 Oct - 30 Oct

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

7. Sleep Inn & Suites Hannibal West

4.1 mi from Mark Twain Boyhood Home and Museum

Patricia

£102

includes taxes & fees

11 Oct - 12 Oct

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

8. Quality Inn & Suites Hannibal West

4 mi from Mark Twain Boyhood Home and Museum

Gayle

£69

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, a sofa, a desk, and a lamp.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

9. Comfort Inn & Suites - Hannibal

3 mi from Mark Twain Boyhood Home and Museum

Jerry

£66

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a wooden headboard, a nightstand with a phone and lamp, and a large sunset painting above the beds.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

A reception area with a marble counter, a 'Days Inn' sign, and a welcome mat.

A corner kitchenette with a refrigerator, coffee maker, and food display.

10. Days Inn by Wyndham Hannibal

3.1 mi from Mark Twain Boyhood Home and Museum

Christian

£45

includes taxes & fees

5 Oct - 6 Oct

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A kitchen with wooden cabinets, a granite countertop, and various food items and kitchen appliances.

A hotel room with two beds, a desk, a chair, and a telephone.

11. Howard Johnson BY Wyndham Hannibal

3.1 mi from Mark Twain Boyhood Home and Museum

Debbie

£55

includes taxes & fees

4 Oct - 5 Oct

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A gym with cardio equipment, mirrored walls, and a view of a Pepsi store outside.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

12. Baymont by Wyndham Hannibal

3.1 mi from Mark Twain Boyhood Home and Museum

brian

£54

includes taxes & fees

1 Oct - 2 Oct

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Compare popular hotels close to Mark Twain Boyhood Home and Museum

Property	Property class	Guest rating
Riverside Inn Hannibal	9.6 Exceptional 199 reviews	View
Best Western On The River	8.8 Excellent 1,013 reviews	View
Lighthouse Inn & Suites	8.8 Excellent 46 reviews	View
Garden House Bed and Breakfast	8.4 Very good 53 reviews	View
Motel 6 Hannibal, MO	7.4 Good 1,001 reviews	View

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Best Western On The River

10/10 Excellent

"The hotel is sleek and modern without being fancy. The location was fantastic, the staff was very helpful, and the pool was a lovely way to start or end the day."

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

10/10 Excellent

"We went for a weekend to check out Hannibal. The property is walkable to just about everything! We really enjoyed all of the food options close by. Vino was our favorite—especially if you need somewhere to eat after 8pm. The host had so much available to us, and even left some snacks and a couple of water bottles. My husband and I are both grad students, so we needed the WiFi for a bit while we were there to do homework, and it worked really well. The library felt very clean and comfortable. Perfect for the two of us. We will definitely be back."

Comfort Inn & Suites - Hannibal

10/10 Excellent

"Rooms were clean. Staff was friendly."

Quality Inn & Suites Hannibal West

8/10 Good

"This was a great stop on our Mississippi River travels"

Riverside Inn Hannibal

10/10 Excellent

"Great place to stay!!"

Motel 6 Hannibal, MO

10/10 Excellent

"Friendly staff."

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

10/10 Excellent

"Loved this house perfect for what we needed."

Garden House Bed and Breakfast....Cozy 1895 Queen Anne Victorian,

8/10 Good

"We really enjoyed our stay and especially loved the cat hostess. We are both cat lovers and are without cats at the moment so that was just sweet. We were disappointed to find that breakfast wasn’t served at the bed-and-breakfast and which was advertised on the in the listing, but our host said that it was a separate add-on, Chris, our host was very helpful when we accidentally left a bag behind and we had to drive over and pick it up from him. He was very gracious to meet us."

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

8/10 Good

"This house is very old and interesting with some interesting history. I love old houses and this place has some unique details. The pool was an added detail that we didn’t use much, but would be fun for families with children. The surrounding back yard was very private and shady. Convenient to downtown and the river."

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a trip to Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savour the top-notch restaurants.

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Planters Barn Theater

8.8/10 (22 reviews)

Get tickets for a show at Planters Barn Theater, a popular theatre in Hannibal. While in this walkable area, you can savour the top-notch restaurants.

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Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)

You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your holiday in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Bluff City Theater

7.6/10 (5 reviews)

Get tickets for a show at Bluff City Theater, a theatre with a story to tell in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Molly Brown Museum and Home

8.4/10 (64 reviews)

You can browse the exhibits at Molly Brown Museum and Home, a museum with a story of its own, during your holiday in Hannibal. While in this walkable area, you can savour the top-notch restaurants.

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Lovers Leap

8.8/10 (171 reviews)

Find out about the history of Hannibal when you spend time at Lovers Leap. While in this walkable area, you can savour the top-notch restaurants.

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Riverview Park

You can find out about the history of Hannibal when you stop by Riverview Park. While in this family-friendly area, you can savour the top-notch restaurants.

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Sodalis Nature Preserve

Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Frequently asked questions

What's the area like around Mark Twain Boyhood Home and Museum?

Mark Twain Boyhood Home and Museum is located in a welcoming area of Hannibal known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 40 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Mark Twain Boyhood Home and Museum?

Adjacent to Mark Twain Boyhood Home and Museum, Best Western On The River is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Lighthouse Inn & Suites and Garden House Bed and Breakfast.

How many hotels will I find near Mark Twain Boyhood Home and Museum?

Expedia has 40 hotels and other accommodation options within a mile from Mark Twain Boyhood Home and Museum.

If I need to cancel the hotel reservation for my stay near Mark Twain Boyhood Home and Museum, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Mark Twain Boyhood Home and Museum.

What can I see and do near Mark Twain Boyhood Home and Museum?

You'll want to browse the exhibits at Jim's Journey: The Huck Finn Freedom Center and Molly Brown Museum and Home. Mark Twain Memorial Lighthouse, Rockcliffe Mansion and Mark Twain Cave are notable landmarks to explore if you're in the area. You can enjoy live performances at Bluff City Theater and Planters Barn Theater.

Search Hotels Near Mark Twain Boyhood Home and Museum, Hannibal

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Mark Twain Boyhood Home and Museum hotels

1. Riverside Inn Hannibal

2. Best Western On The River

3. Lighthouse Inn & Suites

4. Garden House Bed and Breakfast

5. Motel 6 Hannibal, MO

6. Super 8 by Wyndham Hannibal

7. Sleep Inn & Suites Hannibal West

8. Quality Inn & Suites Hannibal West

9. Comfort Inn & Suites - Hannibal

10. Days Inn by Wyndham Hannibal

11. Howard Johnson BY Wyndham Hannibal

12. Baymont by Wyndham Hannibal

Compare popular hotels close to Mark Twain Boyhood Home and Museum

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Best Western On The River

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

Comfort Inn & Suites - Hannibal

Quality Inn & Suites Hannibal West

Riverside Inn Hannibal

Motel 6 Hannibal, MO

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Garden House Bed and Breakfast....Cozy 1895 Queen Anne Victorian,

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

Planters Barn Theater

Jim's Journey: The Huck Finn Freedom Center

Bluff City Theater

Molly Brown Museum and Home

Lovers Leap

Riverview Park

Sodalis Nature Preserve

Frequently asked questions