Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5
Nectar
Collect Nectar points
Nectar
Collect Nectar points
Nectar
Collect Nectar points

Save up to 17% by booking Flight + Hotel.

Search 590,000 properties and 550 airlines worldwide.


Main Street Cultural District Vacation Packages

Main Street Cultural District is just one of the neighborhoods in Ames, a place that 59,000 people call home.

Packages in Main Street Cultural District

Expedia has hotel and flight packages that will give you instant savings. You will have one less thing to stress about when you buy hotel and flight packages with us. With the extra money, now you'll be able to do a little extra shopping in Main Street Cultural District.

Save up to 17% when you get your Main Street Cultural District package deal.

You can select from approximately 400 partner airlines and 321,000 worldwide hotels on our comprehensive international database of lodgings and flights.

Your Ames getaway will seem that much nicer with Expedia's competitive prices.

Almost all accommodation purchases can be cancelled with no added fees from us.

Main Street Cultural District Vacation Packages

Main Street Cultural District sits 35 miles to the north of Des Moines International Airport and 2 miles from the heart of the city.

Ready to go to some nearby tourist sites? Two of the first-rate ones are Octagon Center for the Arts and Furman Aquatic Center. Many also like to go to Brunnier Art Museum and Iowa State Center.

Sports lovers should get tickets for Jack Trice Stadium to see the Iowa State Cyclones playing their visiting rivals. On game days, follow the endless sea of cardinal and gold to the stadium. After the final siren sounds, join fellow college football enthusiasts at a nearby bar or pub for a few post-game beverages.

Accommodation in Main Street Cultural District

Before you get going, make a booking for one of the 20 Main Street Cultural District lodgings listed on Expedia's hotel website.

The Holiday Inn Express & Suites Ames and Holiday Inn Ames Conference Center - ISU are the main lodgings in and around Main Street Cultural District.


Top Hotel Deals

See all 31 Hotels in Main Street Cultural District
Microtel Inn & Suites by Wyndham Ames £44
Microtel Inn & Suites by Wyndham Ames

Microtel Inn & Suites by Wyndham Ames

2216 Se 16th St, Ames
     
    3.9
    of 5, from 857 reviews
    2.0 out of 5.0

    Located in the heart of Ames, this hotel is within 3 miles (5 km) of Octagon Center for the Arts, Reiman Gardens and Jack Trice Stadium. Main Street Cultural District and Hilton Coliseum are also within 6 miles (10 km).

    Baymont by Wyndham Ames £52
    Baymont by Wyndham Ames

    Baymont by Wyndham Ames

    1605 S Dayton Ave, Ames
       
      3.4
      of 5, from 415 reviews
      2.0 out of 5.0

      Situated in Ames, this hotel is within 3 miles (5 km) of Octagon Center for the Arts, Reiman Gardens and Jack Trice Stadium. Main Street Cultural District and Hilton Coliseum are also within 6 miles (10 km).

      Red Roof Inn Ames £48
      Red Roof Inn Ames

      Red Roof Inn Ames

      1400 S Dayton Place, Ames
         
        3.9
        of 5, from 451 reviews
        2.5 out of 5.0

        Situated in a rural location, this hotel is 2.6 mi (4.2 km) from Octagon Center for the Arts and within 6 miles (10 km) of Main Street Cultural District and Jack Trice Stadium. Reiman Gardens and Hilton Coliseum are also within 6 miles (10 km).

        Gateway Hotel and Conference Center £74
        Gateway Hotel and Conference Center

        Gateway Hotel and Conference Center

        2100 Green Hills Drive, Ames
           
          4.3
          of 5, from 768 reviews
          3.0 out of 5.0

          Situated near the airport, this hotel is within 2 miles (3 km) of Reiman Gardens, Jack Trice Stadium and Stephens Auditorium. Hilton Coliseum and Iowa State Center are also within 2 miles (3 km).

          AmericInn by Wyndham Ames £73
          AmericInn by Wyndham Ames

          AmericInn by Wyndham Ames

          2507 SE 16th St., Ames
             
            4.2
            of 5, from 212 reviews
            2.5 out of 5.0

            Situated in Ames, this hotel is 2.9 mi (4.6 km) from Octagon Center for the Arts and within 6 miles (10 km) of Jack Trice Stadium and Hilton Coliseum. Brunnier Art Museum and Iowa State Center are also within 6 miles (10 km).

            Econo Lodge Ames £48
            Econo Lodge Ames

            Econo Lodge Ames

            2600 Se 16th St, Ames
               
              3.6
              of 5, from 439 reviews
              2.0 out of 5.0

              Situated in Ames, this hotel is 2.8 mi (4.6 km) from Octagon Center for the Arts and within 6 miles (10 km) of Jack Trice Stadium and Main Street Cultural District. Reiman Gardens and Hilton Coliseum are also within 6 miles (10 km).

              TownePlace Suites by Marriott Ames £99
              TownePlace Suites by Marriott Ames

              TownePlace Suites by Marriott Ames

              1523 South Dayton Avenue, Ames
                 
                4.6
                of 5, from 34 reviews
                2.5 out of 5.0

                Situated in Ames, this hotel is within 3 miles (5 km) of Octagon Center for the Arts, Reiman Gardens and Jack Trice Stadium. Stephens Auditorium and Hilton Coliseum are also within 6 miles (10 km).

                Holiday Inn Express & Suites Ames £75
                Holiday Inn Express & Suites Ames

                Holiday Inn Express & Suites Ames

                2600 E 13th St, Ames
                   
                  4.0
                  of 5, from 164 reviews
                  2.5 out of 5.0

                  Located in the heart of Ames, this hotel is 2.3 mi (3.7 km) from Octagon Center for the Arts and within 6 miles (10 km) of Main Street Cultural District and Farm House Museum. Veenker Memorial Golf Course and Iowa State University are also within 6 miles (10 km).

                  Top Deals on Flights

                  These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.