COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Book Looe Key National Marine Sanctuary Holidays
Holiday Travel Guide

Top things to do in Looe Key National Marine Sanctuary

Top Trending Hotels Near Looe Key National Marine Sanctuary

Key Home With Open Water Access!!
Key Home With Open Water Access!!
31464 Ave G, Big Pine Key, FL
Get Rates

Located in Sands, this holiday home is 1.1 mi (1.7 km) from National Key Deer Refuge Visitor Center and within 6 miles (10 km) of No Name Key and Cook Island. ...

Key Home With Open Water Access!!
2 Bedroom Accommodation in Big Pine Key
2 Bedroom Accommodation in Big Pine Key
31508 Avenue F, Big Pine Key, FL
Get Rates

Located in Sands, this holiday home is 1.1 mi (1.7 km) from National Key Deer Refuge Visitor Center and within 6 miles (10 km) of No Name Key and Cook Island. ...

2 Bedroom Accommodation in Big Pine Key
3 BEDROOM BEACH HOUSE CLOSE TO BEACH & KEY WEST
3 BEDROOM BEACH HOUSE CLOSE TO BEACH & KEY WEST
31557 Ave A, Big Pine Key, FL
The price is £555 per night from 20 Apr to 21 Apr

Located in Sands, this holiday home is 0.9 mi (1.4 km) from National Key Deer Refuge Visitor Center and within 6 miles (10 km) of No Name Key and Cook Island. ...

4.2/5Very Good! (11 reviews)
Wonderful beach house

"The house is really nice. We had a great time staying there. Very close to La Honda beach - which has a lot of cool tide pools full of Horseshoe crabs, hermit crabs, sea slugs, etc... Big grocery store close by (Winn Dixie)."…"

Reviewed on 19 Jan 2021

3 BEDROOM BEACH HOUSE CLOSE TO BEACH & KEY WEST
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Looe Key National Marine Sanctuary Flight + Hotel Deals

Solé Miami, A Noble House Resort
Fontainebleau Miami Beach
EAST Miami
Don't see what you're looking for?
See all available trips from London to Looe Key National Marine Sanctuary
View all trips

Popular places to visit in Looe Key National Marine Sanctuary

Book Looe Key National Marine Sanctuary Holidays

Choose two or more items and save on your trip:

Top Hotel Deals

Key Home With Open Water Access!!
Key Home With Open Water Access!!
31464 Ave G, Big Pine Key, FL
Key Home With Open Water Access!!
2 Bedroom Accommodation in Big Pine Key
2 Bedroom Accommodation in Big Pine Key
31508 Avenue F, Big Pine Key, FL
2 Bedroom Accommodation in Big Pine Key
3 BEDROOM BEACH HOUSE CLOSE TO BEACH & KEY WEST
3 BEDROOM BEACH HOUSE CLOSE TO BEACH & KEY WEST
31557 Ave A, Big Pine Key, FL
The price is £555 per night from 20 Apr to 21 Apr
3 BEDROOM BEACH HOUSE CLOSE TO BEACH & KEY WEST
Old Wooden Bridge Marina
Old Wooden Bridge Marina
2.5 out of 5
1791 Bogie Drive, Big Pine Key, FL
Old Wooden Bridge Marina
Fishermen`s Paradise
Fishermen`s Paradise
31473 Warner Street, Big Pine Key, FL
Fishermen`s Paradise
Prince`s Keys Serenity
Prince`s Keys Serenity
30349 Prince Road, Big Pine Key, FL
Prince`s Keys Serenity
Welcome to Casa Del Mar 305 5251254
Welcome to Casa Del Mar 305 5251254
1733 Sunrise Dr, Big Pine Key, FL
Welcome to Casa Del Mar 305 5251254
Welcome to Casa Del Mar 305 5251254
Welcome to Casa Del Mar 305 5251254
1733 Sunrise Dr, Big Pine Key, FL
Welcome to Casa Del Mar 305 5251254
New Listing 3bd/2bt Sleeps 8 "sunset Paradise Villa" on Canal Big Pine Key
New Listing 3bd/2bt Sleeps 8 "sunset Paradise Villa" on Canal Big Pine Key
30363 Cardinal Ln, Big Pine Key, FL
New Listing 3bd/2bt Sleeps 8 "sunset Paradise Villa" on Canal Big Pine Key
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.