We had a great stay at the Best Western in Lohr! I was with my family and we had 5 people with 2 rooms. The rooms were very spacious, and there was plenty of room for a roll-away bed in the 3 person room.
Only thing to "complain" about was that there was no AC in a nicely renovated hotel. Totally get that most hotels in Germany don't have AC (at least the ones we stayed in), but it would have been nice. They did place a fan in the room to make it more comfortable. The windows also opened which was nice at night (except for the occasional bug that would fly into the room).
Lovely hotel, lovely breakfast, lovely staff. Definitely worth the stop.