Title: The Best Hotels Closest to Guana Tolomato Matanzas National Estuarine Research Reserve in Ponte Vedra Beach - 2026 Updated Prices | Expedia.co.uk [Guana Tolomato Matanzas National Estuarine Research Reserve Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Guana-Tolomato-Matanzas-National-Estuarine-Research-Reserve.d553248621532654534.Car-Hire-Guide)[Guana Tolomato Matanzas National Estuarine Research Reserve Holidays](https://expedia.co.uk/Guana-Tolomato-Matanzas-National-Estuarine-Research-Reserve-South-Ponte-Vedra-Beach.d553248621532654534.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [25 Mar - 26 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532654534&startDate=2026-03-25&endDate=2026-03-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [26 Mar - 27 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532654534&startDate=2026-03-26&endDate=2026-03-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532654534&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532654534&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Guana Tolomato Matanzas National Estuarine Research Reserve hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17600/17534/93e1dcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/17600/17534/8229b5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/17600/17534/1574a719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/20000/17600/17534/4f8331aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn St Augustine Historic District Area [](https://www.expedia.co.uk/St-Augustine-Hotels-Southern-Oaks-Inn.h17534.Hotel-Information) 7.3 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 8.6/10 Excellent (2,040 reviews) "Clean room, good breakfast, friendly staff, comfy bed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mary £56 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Southern-Oaks-Inn.h17534.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/116000000/115970000/115968900/115968821/w3840h2557x0y3-1ec82091.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/116000000/115970000/115968900/115968821/w3840h2557x0y3-2c9ce287.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/116000000/115970000/115968900/115968821/ea52925e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115970000/115968900/115968821/b9c771e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton St. Augustine I-95 [](https://www.expedia.co.uk/St-Augustine-Hotels-Tru-By-Hilton-St-Augustine-I-95.h115968821.Hotel-Information) 9.1 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.2/10 Wonderful (233 reviews) "Clean rooms, great friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Earl £81 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Tru-By-Hilton-St-Augustine-I-95.h115968821.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/93000000/92420000/92418500/92418478/0bfd4cdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/93000000/92420000/92418500/92418478/9f85a766.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92420000/92418500/92418478/83f4b199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92420000/92418500/92418478/42c86566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites St. Augustine Historic District Area [](https://www.expedia.co.uk/St-Augustine-Hotels-Comfort-Suites.h92418478.Hotel-Information) 7.1 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.2/10 Wonderful (1,650 reviews) "Nice spacious room, clean, friendly staff and good location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olivia £91 includes taxes & fees 22 Apr - 23 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Comfort-Suites.h92418478.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/870000/869100/869006/b165807e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/870000/869100/869006/4b69925b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/870000/869100/869006/ac0a1c45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/870000/869100/869006/b894a02d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn St. Augustine Historic District [](https://www.expedia.co.uk/St-Augustine-Hotels-Rodeway-Inn-St-Augustine.h869006.Hotel-Information) 7.2 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 8.4/10 Very good (1,011 reviews) "Very clean hotel, staff was helpful, room was clean, bed was confortable. Will definitely stay there again." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Yann £47 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Rodeway-Inn-St-Augustine.h869006.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1350000/1340500/1340428/aedbbba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1350000/1340500/1340428/cd9c94d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Townhome, 1 King Bed (Room 37) | Living area | 32-inch LED TV with cable channels](https://images.trvl-media.com/lodging/2000000/1350000/1340500/1340428/w4080h2571x0y0-015d2e59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Townhome, 1 King Bed (Room 36) | Individually decorated, individually furnished, soundproofing](https://images.trvl-media.com/lodging/2000000/1350000/1340500/1340428/8b2c9d20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cozy Inn [](https://www.expedia.co.uk/St-Augustine-Hotels-The-Cozy-Inn.h1340428.Hotel-Information) 7.7 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.4/10 Exceptional (1,000 reviews) "The room was clean and the staff very nice. We had 2 very pleasant nights at The Cozy Inn." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kellie £87 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-The-Cozy-Inn.h1340428.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/220000/210300/210286/b866e23a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/220000/210300/210286/2c070cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/220000/210300/210286/c83940bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/220000/210300/210286/8815a377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn St. Augustine - World Golf by IHG [](https://www.expedia.co.uk/St-Augustine-Hotels-Holiday-Inn-St-Augustine-World-Golf.h210286.Hotel-Information) 8.4 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 6.8/10 (1,000 reviews) "Breakfast was good. Room was clean and bed was fairly comfortable. I enjoyed my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beau £74 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Holiday-Inn-St-Augustine-World-Golf.h210286.Hotel-Information) ![Standard Room, 1 King Bed, Accessible (Communications, Roll-In Shower) | Exterior](https://images.trvl-media.com/lodging/61000000/60660000/60652000/60651972/b84a12f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/61000000/60660000/60652000/60651972/c7d413a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/61000000/60660000/60652000/60651972/e2d8da5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/61000000/60660000/60652000/60651972/9f2ab37d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express St. Augustine - Vilano Beach by IHG [](https://www.expedia.co.uk/St-Augustine-Hotels-Holiday-Inn-Express-St-Augustine-Vilano-Beach.h60651972.Hotel-Information) 7.6 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.8/10 Exceptional (703 reviews) "The room was comfortable and breakfast was good too" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason £114 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Holiday-Inn-Express-St-Augustine-Vilano-Beach.h60651972.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/810000/809000/808920/1dcdaed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/810000/809000/808920/0bdf76db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/810000/809000/808920/9829d150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809000/808920/b6ab9541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Sands Beach Boutique Inn - 1 Acre Private Beach [](https://www.expedia.co.uk/St-Augustine-Hotels-Ocean-Sands-Beach-Inn.h808920.Hotel-Information) 6.3 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 8.8/10 Excellent (711 reviews) "The property and the amenities are very nice and welcoming. We really enjoyed our stay overall. The ocean view was an unexpected bonus. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike £152 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Ocean-Sands-Beach-Inn.h808920.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/3000000/2350000/2345700/2345615/20d36edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2350000/2345700/2345615/3233fb71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gold Room - Premium in private Cottage (Adults 21+ Only) | Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/3000000/2350000/2345700/2345615/1fe106e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/3000000/2350000/2345700/2345615/92a08ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carriage Way Inn [](https://www.expedia.co.uk/St-Augustine-Hotels-Carriage-Way-Bed-Breakfast.h2345615.Hotel-Information) 8.9 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.8/10 Exceptional (745 reviews) "Very nice bed & breakfast. Would definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £141 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Carriage-Way-Bed-Breakfast.h2345615.Hotel-Information) ![Standard Studio, Balcony, Harbour View | Living area | 40-inch TV with cable channels](https://images.trvl-media.com/lodging/111000000/110870000/110864200/110864149/bf067415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, Balcony, Harbour View | Living area | 40-inch TV with cable channels](https://images.trvl-media.com/lodging/111000000/110870000/110864200/110864149/2d5403f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, Balcony, Harbour View | Living area | 40-inch TV with cable channels](https://images.trvl-media.com/lodging/111000000/110870000/110864200/110864149/5b0eace8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio, Balcony, Harbour View | Individually decorated, individually furnished, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110870000/110864200/110864149/a8a92424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn at Camachee Harbor by Coolvacay [](https://www.expedia.co.uk/St-Augustine-Hotels-Inn-At-Camachee-Harbor.h110864149.Hotel-Information) 7.5 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.4/10 Exceptional (280 reviews) "Very clean and accommodating staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose Miguel £131 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Inn-At-Camachee-Harbor.h110864149.Hotel-Information) ![Family Apartment, 1 King Bed with Sofa bed, Kitchen, Courtyard View | Private kitchen | Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/112000000/111280000/111272900/111272843/47c2e6c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment, Multiple Beds, Kitchen, Courtyard View | Private kitchen | Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/112000000/111280000/111272900/111272843/a1c576b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Studio, 1 Queen Bed, Courtyard View, Ground Floor | Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/112000000/111280000/111272900/111272843/d7b2fa6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment, Multiple Beds, Kitchen, Courtyard View | Living area | 50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/112000000/111280000/111272900/111272843/58d0c668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Haleys Court Boutique Motel [](https://www.expedia.co.uk/St-Augustine-Hotels-Haleys-Court-Boutique-Motel.h111272843.Hotel-Information) 7.6 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.8/10 Exceptional (150 reviews) "Cute 1940’s motel with an amazing renovation. Loved the style, cleanliness, location, and amenities, including laundry facilities. I hope to stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tara £132 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/St-Augustine-Hotels-Haleys-Court-Boutique-Motel.h111272843.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11110000/11109400/11109384/10762db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/12000000/11110000/11109400/11109384/6876f9a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11110000/11109400/11109384/c9841b36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11110000/11109400/11109384/c040186a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Castillo Inn [](https://www.expedia.co.uk/St-Augustine-Hotels-Scottish-Inn.h11109384.Hotel-Information) 8.3 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 6.6/10 (764 reviews) "The check in process was very easy, the staff was very nice. Very friendly, the location was perfect. The overall cleanliness was good and the beds were very comfortable. I would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) tanya £62 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Scottish-Inn.h11109384.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/12000000/11480000/11476600/11476563/f0272d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![KING BED SECOND FLOOR | Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11480000/11476600/11476563/a281d3d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![KING BED GROUND FLOOR | Bathroom | Combined shower/bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11480000/11476600/11476563/3c4fc658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/12000000/11480000/11476600/11476563/a369b439.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Economy Inn [](https://www.expedia.co.uk/St-Augustine-Hotels-Economy-Inn.h11476563.Hotel-Information) 8.3 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 8.6/10 Excellent (560 reviews) "Great area, lots of cute shops and restaurants , nearby and easy walking distance to the historic area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARY £60 includes taxes & fees 1 Apr - 2 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Economy-Inn.h11476563.Hotel-Information) ![Room, 1 King Bed, Non Smoking | Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2030000/2027700/2027601/fd1d7597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2030000/2027700/2027601/a9776dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2030000/2027700/2027601/5437c78d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/3000000/2030000/2027700/2027601/2367ab7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham St. Augustine [](https://www.expedia.co.uk/St-Augustine-Hotels-La-Quinta-Inn-Suites-By-Wyndham-St-Augustine.h2027601.Hotel-Information) 8.8 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 7.8/10 Good (1,483 reviews) "Nice room and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto £55 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-La-Quinta-Inn-Suites-By-Wyndham-St-Augustine.h2027601.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/55200/55182/b1baa93b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/55200/55182/75427b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/60000/55200/55182/e189538f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/55200/55182/434c18e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Augustine US1 North [](https://www.expedia.co.uk/St-Augustine-Hotels-Hampton-Inn-St-Augustine-Historic-District.h55182.Hotel-Information) 7.7 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 8.4/10 Very good (1,002 reviews) "great staff good location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale £95 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Hampton-Inn-St-Augustine-Historic-District.h55182.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/13000000/12780000/12770800/12770740/6e902437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12780000/12770800/12770740/b53f8485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12780000/12770800/12770740/4a458485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Desk, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/13000000/12780000/12770800/12770740/a1dfdf44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Smart Stay Inn [](https://www.expedia.co.uk/St-Augustine-Hotels-The-Smart-Stay-Inn.h12770740.Hotel-Information) 9 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 8.6/10 Excellent (2,023 reviews) "Great place to stopover for the night. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mari £70 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/St-Augustine-Hotels-The-Smart-Stay-Inn.h12770740.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/75000000/74100000/74098300/74098255/5bd1e151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/75000000/74100000/74098300/74098255/a6a0ab2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/75000000/74100000/74098300/74098255/b2f78273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74100000/74098300/74098255/450f270d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place St. Augustine/Vilano Beach [](https://www.expedia.co.uk/St-Augustine-Hotels-Hyatt-Place-St-AugustineVilano-Beach.h74098255.Hotel-Information) 7.6 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.4/10 Exceptional (1,233 reviews) "Everything was great, wonderful place, staff & location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl L £124 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Hyatt-Place-St-AugustineVilano-Beach.h74098255.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/50000/41500/41440/87c134e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/41500/41440/d0955cea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/41500/41440/6ca0284c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/41500/41440/802a812c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance St. Augustine Historic Downtown Hotel [](https://www.expedia.co.uk/St-Augustine-Hotels-Renaissance-St-Augustine-Historic-Downtown-Hotel.h41440.Hotel-Information) 8.6 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 9.4/10 Exceptional (462 reviews) "Room was big and very comfortable and clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracey £171 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Renaissance-St-Augustine-Historic-Downtown-Hotel.h41440.Hotel-Information) ![Beach House - 2nd Floor | Living area | 32-inch TV with cable channels](https://images.trvl-media.com/lodging/2000000/1420000/1414000/1413974/d72ecd13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/2000000/1420000/1414000/1413974/5b41ba97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![King Jacuzzi - 2nd Floor | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1420000/1414000/1413974/dc3b14fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach House - 2nd Floor | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1420000/1414000/1413974/w1280h1105x0y0-639c33d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oceanview Lodge [](https://www.expedia.co.uk/St-Augustine-Hotels-Oceanview-Lodge.h1413974.Hotel-Information) 7.7 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 8.8/10 Excellent (1,000 reviews) "A great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wendy £116 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-Oceanview-Lodge.h1413974.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/7000/6922/26836a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/7000/6922/a04272cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7000/6922/e17a8ad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/7000/6922/e8761eaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ponce St. Augustine Hotel [](https://www.expedia.co.uk/St-Augustine-Hotels-The-Ponce-St-Augustine-Hotel.h6922.Hotel-Information) 8.3 mi from Guana Tolomato Matanzas National Estuarine Research Reserve 8.2/10 Very good (1,413 reviews) "Friendly staff, clean room, nice showers, comfortable bed! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dayven £84 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Augustine-Hotels-The-Ponce-St-Augustine-Hotel.h6922.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-09&endDate=2026-04-10®ionId=553248621532654534&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | ----------------- | --------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17600/17534/93e1dcc7.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Quality Inn St Augustine Historic District Area | 3.0 star property | 8.6Excellent2,040 reviews | View | | | | | | | ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/116000000/115970000/115968900/115968821/w3840h2557x0y3-1ec82091.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Tru By Hilton St. Augustine I-95 | 2.5 star property | 9.2Wonderful233 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/93000000/92420000/92418500/92418478/0bfd4cdb.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Comfort Suites St. Augustine Historic District Area | 2.5 star property | 9.2Wonderful1,650 reviews | View | | | | | | | ![Reception](https://images.trvl-media.com/lodging/1000000/870000/869100/869006/b165807e.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Rodeway Inn St. Augustine Historic District | 2.0 star property | 8.4Very good1,011 reviews | View | | | | | | | ![Front of property](https://images.trvl-media.com/lodging/2000000/1350000/1340500/1340428/aedbbba2.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)The Cozy Inn | 2.0 star property | 9.4Exceptional1,000 reviews | View | | | | | | ## Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel Reviews ![Ocean front single family home fully fenced yard!](https://images.trvl-media.com/lodging/25000000/24090000/24089100/24089079/701b7332_y.jpg) ### Ocean front single family home fully fenced yard! 10/10 Excellent "The property was awesome and provide the perfect respite for our family. Our pets were welcome as well. Highly recommend this rental and the area as a whole." [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-Ocean-Front-Single-Family-Home-Fully-Fenced-Yard.h24089079.Hotel-Information) ![Sandy Feet Retreat Beach Front, Sleeps 8 Adults and 3 Children](https://images.trvl-media.com/lodging/68000000/67380000/67371100/67371049/42a24814_y.jpg) ### Sandy Feet Retreat Beach Front, Sleeps 8 Adults and 3 Children 10/10 Excellent "The house was just as described and the host was quick to reply to my questions. Everything was clean and the beds were comfortable. I packed way more than I needed to because they had just about everything we needed to enjoy a day on the beach, umbrellas, beach towels, sand toys, and chairs are available to use. There were also child/dog gates available which we used to put at the top of the stairs outside so the dogs could have some time off leashes, which they enjoyed. We enjoyed everything about this house and will definitely stay there again if we travel back to Florida. " [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-Meticulously-Maintained-Oceanfront-Home-Sleeps-10.h67371049.Hotel-Information) ![Spacious Oceanfront 4 br/3ba Close to TPC and St Augustine](https://images.trvl-media.com/lodging/58000000/57890000/57882800/57882751/w1024h767x0y1-2b7e3455_y.jpg) ### Spacious Oceanfront 4 br/3ba Close to TPC and St Augustine 10/10 Excellent "Excellent house, beautifully maintained and ideally located on the beach, offering stunning views of both sunrise and sunset at the horizon. Each room is spacious and thoughtfully designed, and the kitchen is one of the most expansive and well-equipped I have seen in a property like this. Thanks for good memories " [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-Spacious-Oceanfront-4-Br3ba-Close-To-TPC-And-St-Augustine.h57882751.Hotel-Information) ![Beachfront Paradise Ponte Vedra](https://images.trvl-media.com/lodging/125000000/124820000/124816200/124816191/ef8c5daa_y.jpg) ### Beachfront Paradise Ponte Vedra 8/10 Good "We had a wonderful stay at Beach Front Paradise in Ponte Vedra. The home was very clean and comfortable, and we really appreciated the thoughtful touches throughout the property. While there are a few minor repairs that could be addressed, they did not take away from our overall experience.The beach access was truly the best part of this stay. Being just a few steps from the back door made it incredibly convenient, and we loved that the property provided plenty of beach items and toys to enjoy. The peaceful, natural beach setting made it easy to relax and unwind.The morning views were absolutely priceless. Sitting and listening to the ocean while watching the sunrise made this trip especially memorable. Overall, we had a very relaxing stay and really enjoyed the location and easy access to such a beautiful stretch of beach. " [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-Beachfront-Paradise-Ponte-Vedra.h124816191.Hotel-Information) ![Weekend Special Escape The Cold and Warm Your Heart at The Blue Gem Beach House](https://images.trvl-media.com/lodging/102000000/101360000/101355900/101355899/w1093h773x0y0-8d4e4a98_y.jpg) ### Weekend Special Escape The Cold and Warm Your Heart at The Blue Gem Beach House 10/10 Excellent "Wonderful stay at the Blue Gem. The views are amazing, the house was well equipped, and host was kind and attentive. We hope to visit again next year." [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-Kick-Off-2026-At-The-Blue-Gem-Beach-House-A-Beautiful-Beginning.h101355899.Hotel-Information) ![Turtle's Nest - Wren Beach Rentals by Portoro](https://images.trvl-media.com/lodging/103000000/102770000/102762100/102762079/1ce08056_y.jpg) ### Turtle's Nest - Wren Beach Rentals by Portoro 10/10 Excellent "Unobstructed beach front property that offers everything described and then some. Look forward to staying again in the future! " [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-Turtles-Nest-Wren-Beach-Rentals-By-Portoro.h102762079.Hotel-Information) ![Oceanfront Private Beach Access, Groups & Families](https://images.trvl-media.com/lodging/92000000/91900000/91894500/91894443/a77d8fd2_y.jpg) ### Oceanfront Private Beach Access, Groups & Families 10/10 Excellent "Lovely house right on the each, steps from the beach with an unobstucted view. Plenty of room for a family. Big common room. Large oceanfront deck. The hosts responded immediately to our questions. It was a seamless visit. I will stay here again." [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-Oceanfront-Privacy-Mid-Century-Modern-Vibe.h91894443.Hotel-Information) ![South Ponte Vedra Oceanfront Estate](https://images.trvl-media.com/lodging/97000000/96450000/96443100/96443063/w1200h799x0y1-dac3f8f7_y.jpg) ### South Ponte Vedra Oceanfront Estate 10/10 Excellent "Absolutely fabulous " [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-South-Ponte-Vedra-Oceanfront-Estate.h96443063.Hotel-Information) ![BonVue Oceanfront House in Ponte Vedra Beach / St Aug](https://images.trvl-media.com/lodging/64000000/63750000/63742500/63742426/e6281d9e_y.jpg) ### BonVue Oceanfront House in Ponte Vedra Beach / St Aug 10/10 Excellent "The house was great and the view was fantastic! We had a wonderful time and will return next year." [](https://expedia.co.uk/Ponte-Vedra-Beach-Hotels-Pure-Bliss-Oceanfront-House-In-Ponte-Vedra-Beach-St-Aug.h63742426.Hotel-Information) ## Hotels near other Guana Tolomato Matanzas National Estuarine Research Reserve attractions ### Guana Pine State Park and Wildlife Management Area Explore the lovely green spaces of Guana Pine State Park and Wildlife Management Area and enjoy the golf courses in Ponte Vedra Beach. Wander the beautiful beaches and seaside in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654535) ### South Ponte Vedra Beach Why not spend a lazy afternoon at South Ponte Vedra Beach during your trip to Ponte Vedra Beach? [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=813536013130342400) ### Guana River Wildlife Management Area You can take time to visit Guana River Wildlife Management Area during your travels to Ponte Vedra Beach. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874555415348887552) ### Water + Stone Gallery You can browse the exhibits at Water + Stone Gallery, a museum with a storied past, during your travels to St. Augustine. Wander the beautiful beaches and seaside in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561885960) ### Castle Otttis Castle Otttis is just one of the places to see in St. Augustine, so why not enjoy the other things to explore during your travels? Wander the beautiful beaches and seaside in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561885958) ### Usina Beach Why not spend a care-free afternoon at Usina Beach during your travels in South Ponte Vedra Beach? [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248623743246783) ### The Schoolyard The Schoolyard is just one of the places to see in Nocatee, so why not enjoy the other things to explore during your travels? [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=874556908927959040) ## Frequently asked questions ### What's the area like around Guana Tolomato Matanzas National Estuarine Research Reserve? ### What's the best hotel to stay close to Guana Tolomato Matanzas National Estuarine Research Reserve? ### How many hotels should I expect to find close to Guana Tolomato Matanzas National Estuarine Research Reserve? ### If I need to cancel the hotel reservation for my stay near Guana Tolomato Matanzas National Estuarine Research Reserve, will I receive a refund?