Search Hotels Near Guana Tolomato Matanzas National Estuarine Research Reserve, Ponte Vedra Beach

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6 Nov - 7 Nov
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7 Nov - 8 Nov
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6 Nov - 8 Nov
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13 Nov - 15 Nov

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Our top choices for Guana Tolomato Matanzas National Estuarine Research Reserve hotels

A modern breakfast area with a self-service counter, seating, and a beverage station.

1. Tru By Hilton St. Augustine I-95

Tru By Hilton St. Augustine I-95
2.5 star property
9.1 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
9.4 out of 10, Exceptional, (497 reviews)
"Awesome stay, quiet and super friendly staff!"
United States
Holly
The price is £75
includes taxes & fees
30 Nov - 1 Dec
Tru By Hilton St. Augustine I-95
A spacious indoor area with hexagonal tile flooring, multiple seating arrangements including bar stools and tables, ceiling fans, and hanging pendant lights.

2. Hyatt Place St. Augustine/Vilano Beach

Hyatt Place St. Augustine/Vilano Beach
3.0 star property
7.6 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
9.2 out of 10, Wonderful, (1,630 reviews)
"Clean room, location, breakfast"
United States
Brenna
The price is £104
includes taxes & fees
18 Nov - 19 Nov
Hyatt Place St. Augustine/Vilano Beach
A reception area with leather sofas, a glass coffee table, and a reception desk.

3. Regency Inn & Suites

Regency Inn & Suites
2.0 star property
12 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.4 out of 10, Very good, (1,307 reviews)
"Front desk staff very nice, its a good location near the beach and restaurants."
United States
Joel
The price is £52
includes taxes & fees
8 Nov - 9 Nov
Regency Inn & Suites
A hot tub with a metal ladder, surrounded by lounge chairs and a pool.

4. The Smart Stay Inn

The Smart Stay Inn
2.5 star property
9 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.6 out of 10, Excellent, (2,208 reviews)
"Clean, friendly, wonderful breakfast"
United States
Jeremy
The price is £59
includes taxes & fees
11 Nov - 12 Nov
The Smart Stay Inn
An aerial view of a beach with a long pier extending into the ocean, adjacent to a sandy shore with buildings and parked cars.

5. Ocean Breeze Inn

Ocean Breeze Inn
2.0 star property
11.9 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.2 out of 10, Very good, (1,166 reviews)
"Very kind staff, if I return to this area,, I will definitely stay here again. Beautiful town."
United States
David
The price is £53
includes taxes & fees
8 Nov - 9 Nov
Ocean Breeze Inn
A modern hotel lobby with a stone accent wall, a round dining table, and comfortable seating.

6. Fairfield Inn & Suites by Marriott St. Augustine I-95

Fairfield Inn & Suites by Marriott St. Augustine I-95
3.0 star property
8.8 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.8 out of 10, Excellent, (1,002 reviews)
"Room was nice, clean and spacious, hot breakfast was delicious, lots of shopping, restaurants nearby, will definitely stay again"
United States
Brian
The price is £77
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott St. Augustine I-95
A covered corridor with a tiled floor, wooden ceiling, and green pillars.

7. Holiday Inn Express St. Augustine - Vilano Beach by IHG

Holiday Inn Express St. Augustine - Vilano Beach by IHG
3.5 star property
7.6 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
9.8 out of 10, Exceptional, (767 reviews)
"Breakfast staff was exceptional…everyone working was friendly, kind, and gracious. It was an excellent stay!"
United States
Kevin
The price is £128
includes taxes & fees
19 Nov - 20 Nov
Holiday Inn Express St. Augustine - Vilano Beach by IHG
A hotel with a swimming pool, multiple balconies, and lounge chairs.

8. Hampton Inn St. Augustine Beach

Hampton Inn St. Augustine Beach
2.5 star property
12.2 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.8 out of 10, Excellent, (1,001 reviews)
"Location was very good - breakfast was great !"
United States
Phillisa
The price is £105
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn St. Augustine Beach
A table with a bottle of Meomi wine and two glasses, overlooking a beach with rough waves.

9. The Saint Augustine Beach House

The Saint Augustine Beach House
2.5 star property
7.7 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
9.6 out of 10, Exceptional, (697 reviews)
"We really enjoyed our stay!"
United States
Jessica
The price is £212
includes taxes & fees
16 Nov - 17 Nov
The Saint Augustine Beach House
An upper front porch with a white floor, black railings, and two rocking chairs.

10. Zora's Sojourn

Zora's Sojourn
3.0 star property
9.3 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
10.0 out of 10, Exceptional, (15 reviews)
"We had a wonderful stay! The place was very nice, clean, and well kept. Everything was exactly as described, and you can tell the owners take great care of the property. We really enjoyed our time here and felt comfortable throughout our stay. We would definitely love to come back and highly recommend it to anyone looking for a great place to stay!"
United States
Daniela
The price is £108
includes taxes & fees
7 Nov - 8 Nov
Zora's Sojourn
A modern kitchen with white countertops, a stainless steel sink, a coffee maker, and a window with a view of the outside.

11. Haleys Court Boutique Motel

Haleys Court Boutique Motel
2.0 star property
7.6 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
9.8 out of 10, Exceptional, (209 reviews)
"What an adorable place to stay! In walking distance to the beach, the grocery store, and places to eat. Absolutely loved our stay and will be back! ❤️"
United States
Paula
The price is £121
includes taxes & fees
9 Nov - 10 Nov
Haleys Court Boutique Motel
A spacious hotel lobby with a reception desk, seating area with sofas, and a large window providing natural light.

12. Comfort Suites St. Augustine Historic District Area

Comfort Suites St. Augustine Historic District Area
2.5 star property
7.1 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
9.2 out of 10, Wonderful, (1,803 reviews)
"Great staff, clean room, great breakfast"
United States
Sandra
The price is £90
includes taxes & fees
8 Nov - 9 Nov
Comfort Suites St. Augustine Historic District Area
A hotel room with two beds, a desk, a chair, a mirror, and artwork on the wall.

13. Days Inn by Wyndham St. Augustine I-95/Outlet Mall

Days Inn by Wyndham St. Augustine I-95/Outlet Mall
2.0 star property
9 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.4 out of 10, Very good, (162 reviews)
"Great value for money stay. Perfect for an overnight."
United States
Chrishando
The price is £53
includes taxes & fees
15 Nov - 16 Nov
Days Inn by Wyndham St. Augustine I-95/Outlet Mall
A modern kitchen with white cabinets and a stainless steel oven.

14. Inn at Camachee Harbor by Coolvacay

Inn at Camachee Harbor by Coolvacay
2.0 star property
7.5 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
9.4 out of 10, Exceptional, (348 reviews)
"Great location and apartment was super clean"
United States
Osmide
The price is £114
includes taxes & fees
8 Nov - 9 Nov
Inn at Camachee Harbor by Coolvacay
A building with a covered porch, outdoor lighting, and greenery.

15. Quality Inn St Augustine Historic District Area

Quality Inn St Augustine Historic District Area
3.0 star property
7.3 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.4 out of 10, Very good, (2,244 reviews)
"Great service nice rooms and beautiful location"
United States
Weston
The price is £56
includes taxes & fees
8 Nov - 9 Nov
Quality Inn St Augustine Historic District Area
A garden with a palm tree, a fountain, and potted plants with pink flowers.

16. Merida Inn and Suites

Merida Inn and Suites
2.0 star property
7.7 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.0 out of 10, Very good, (481 reviews)
"this place is just ok. make sure you have your own toiletries."
United States
Jay
The price is £59
includes taxes & fees
7 Dec - 8 Dec
Merida Inn and Suites
A hotel reception desk with a dark wood finish, two computer monitors, and a sign that reads 'Quality by Choice Hotels'.

17. Quality Inn St. Augustine Outlet Mall

Quality Inn St. Augustine Outlet Mall
2.5 star property
8.8 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.2 out of 10, Very good, (1,000 reviews)
"Very low price; good breakfast; refrigerator, microwave; everything I needed. Receptionist was very friendly."
United States
Cecilia
The price is £55
includes taxes & fees
7 Dec - 8 Dec
Quality Inn St. Augustine Outlet Mall
A balcony with two chairs and a table, overlooking a beach and buildings.

18. Hampton Inn & Suites St. Augustine-Vilano Beach

Hampton Inn & Suites St. Augustine-Vilano Beach
2.5 star property
7.7 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.6 out of 10, Excellent, (1,002 reviews)
"It was just a really nice stay"
United States
PAUL
The price is £81
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites St. Augustine-Vilano Beach
An outdoor patio with a striped sofa, yellow chairs, and a table.

19. Home2 Suites by Hilton St. Augustine I-95

Home2 Suites by Hilton St. Augustine I-95
3.0 star property
8.7 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.8 out of 10, Excellent, (1,000 reviews)
"Great"
United States
Jerron
The price is £81
includes taxes & fees
15 Nov - 16 Nov
Home2 Suites by Hilton St. Augustine I-95
A modern bar area with wooden bar counters, black bar stools, and a variety of bottles and glasses.

20. Courtyard by Marriott St Augustine I-95

Courtyard by Marriott St Augustine I-95
3.0 star property
8.8 mi from Guana Tolomato Matanzas National Estuarine Research Reserve
8.6 out of 10, Excellent, (1,002 reviews)
"Clean room, elegant lobby, decent bar area"
United States
Tam
The price is £69
includes taxes & fees
11 Nov - 12 Nov
Courtyard by Marriott St Augustine I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern breakfast area with a self-service counter, seating, and a beverage station.
Tru By Hilton St. Augustine I-95
2.5 star property
9.4
Exceptional
497 reviews
View
A spacious indoor area with hexagonal tile flooring, multiple seating arrangements including bar stools and tables, ceiling fans, and hanging pendant lights.
Hyatt Place St. Augustine/Vilano Beach
3.0 star property
9.2
Wonderful
1,630 reviews
View
A reception area with leather sofas, a glass coffee table, and a reception desk.
Regency Inn & Suites
2.0 star property
8.4
Very good
1,307 reviews
View
A hot tub with a metal ladder, surrounded by lounge chairs and a pool.
The Smart Stay Inn
2.5 star property
8.6
Excellent
2,208 reviews
View
An aerial view of a beach with a long pier extending into the ocean, adjacent to a sandy shore with buildings and parked cars.
Ocean Breeze Inn
2.0 star property
8.2
Very good
1,166 reviews
View

Other attractions near Guana Tolomato Matanzas National Estuarine Research Reserve

Guana Pine State Park and Wildlife Management Area

8.6/10 (9 reviews)
Explore the lovely green spaces of Guana Pine State Park and Wildlife Management Area and enjoy the golf courses in Ponte Vedra Beach. Wander the beautiful beaches and seaside in the area.
See properties

Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel Reviews

A table with a bottle of Meomi wine and two glasses, overlooking a beach with rough waves.
The Saint Augustine Beach House

The Saint Augustine Beach House

The Saint Augustine Beach House
Vilano Beach

10/10 Excellent

Great location.. very clean.. friendly staff.. nice complementary breakfast.. & the view is awesome.. wonderful stay!
United Kingdom
colby
Reviewed August 11, 2026
The Saint Augustine Beach House

Frequently Asked Questions

What's the area like around Guana Tolomato Matanzas National Estuarine Research Reserve?

Guana Tolomato Matanzas National Estuarine Research Reserve is located in a family-friendly area of Ponte Vedra Beach known for its interesting historical sites and major shopping area. If you're looking for a convenient place to stay, take a look at the 49 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay close to Guana Tolomato Matanzas National Estuarine Research Reserve?

Comfort Suites St. Augustine Historic District Area is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. You'll find it 7.1 mi (11.5 km) from Guana Tolomato Matanzas National Estuarine Research Reserve.

How many hotels should I expect to find close to Guana Tolomato Matanzas National Estuarine Research Reserve?

Expedia has 49 hotels and other accommodation options within a mile from Guana Tolomato Matanzas National Estuarine Research Reserve.

If I need to cancel the hotel reservation for my stay near Guana Tolomato Matanzas National Estuarine Research Reserve, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals available near Guana Tolomato Matanzas National Estuarine Research Reserve.