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I go to Frankfurt every year for the same conference and I usually stay at the Marriott adjacent to Aparthotel. This was the first year I stayed at Aparthotel and I have definitely been missing out. You get way more for a much better price at the Aparthotel than at the Marriott. This is where I am ...
Shuttle service was free although a little behind schedule. Take this into account when selecting your departure time. Staff was very welcoming. Its proximity to the airport is highly appreciated.