Beginning of main content

Florida Keys Hotel Guide - Design Hotel in Florida Keys, United States of America

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Florida Keys Hotels

Search Flight + Hotel

Advanced options

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Florida Keys Design Hotel

See all 265 Hotels in Florida Keys
The Marquesa Hotel
The Marquesa Hotel
600 Fleming Street, Key West
3.5 out of 5.0
4.9 out of 5 (108 reviews)
Hide review
Charming secluded oasis two blocks from Duval St Excellent staff, great location, historic Key West ambience, quiet/tropical courtyard with 2 pools. A revisit designation.
  7 May 2017

£192

£192
The Gates Hotel Key West
The Gates Hotel Key West
3824 N Roosevelt Blvd, Key West
4.0 out of 5.0
4.3 out of 5 (278 reviews)
Hide review
Nice and clean hotel but away from main drag It was very clean and nice plush towels and beddings. Clean and not-crowded salt pool by tiki bar. We had 3kids with us and it accommodated us good for 3 nights. It has small fridge we can put water. It is away from main hub of key west though. There is shuttle.
  4 May 2017

£142

£142
Azul del Mar
Azul del Mar
104300 Overseas Highway, Key Largo
3.5 out of 5.0
4.4 out of 5 (71 reviews)
Hide review
Oasis in Key Largo The Azul is a great, quiet oasis in close proximity to the various attractions of Key Largo. The staff was courteous and extremely helpful in making our time in Key Largo an excellent stay. The architecture of the building is wonderful. I would highly recommend this oasis for your next stay in Key ...
  24 Mar 2017
Weatherstation Inn
Weatherstation Inn
57 Front St, Key West
2.5 out of 5.0
4.7 out of 5 (111 reviews)
Hide review
Beautiful historic Inn. Appreciated the quiet location.
  22 Apr 2017

£217

£217
Artist House Key West
Artist House Key West
534 Eaton Street, Key West
3.5 out of 5.0
4.4 out of 5 (17 reviews)
Hide review
Cozy Retreat Staff was very friendly and helpful. Quick bike ride or walk to Duval St. And Mallory square. A bit noisy but we were given ear plugs due to the ghost tours and general traffic in area.
  5 May 2017

£130

£130
Almond Tree Inn
Almond Tree Inn
512 Truman Ave, Key West
3.5 out of 5.0
4.8 out of 5 (289 reviews)
Hide review
A very nice hotel within walking distance of all t Very pleasant and comfortable. My wife and I enjoyed our visit and would definetly return to this hotel.
  4 May 2017

£240

£240
Artist House on Fleming
Artist House on Fleming
1016 Fleming St., Key West
3.5 out of 5.0
4.6 out of 5 (22 reviews)
Hide review
Great location for peace & quiet, but still close. Artist House was super clean, spacious and exactly as advertised. Great outdoor spaces to relax and an easy walk to Duval. The staff is super friendly, low key and very accommodating. Overall just a great place to stay.
  10 Apr 2017

£154

£154
The Saint Hotel Key West, Autograph Collection
The Saint Hotel Key West, Autograph Collection
417 Eaton Street, Key West
3.5 out of 5.0
4.4 out of 5 (86 reviews)
Hide review
Great Location to Duval and all the activities We really enjoyed The Saint and the fact we could walk about everywhere we wanted. The people were super nice and the hotel had a fun new vibe about it. Beautiful pool. And somehow tucked right in the middle of everything. Our room was super small but that was all that was available. Was prices but ...
  11 May 2017

£164

£164
Drop Anchor Resort and Marina
Drop Anchor Resort and Marina
84959 Overseas Highway, 222, Islamorada
3.0 out of 5.0
4.2 out of 5 (296 reviews)
Hide review
Nice hotel on the water The facility is older but very clean and the staff extremely nice.
  3 May 2017

£108

£108
Orchid Key Inn
Orchid Key Inn
1004 Duval St, Key West
3.5 out of 5.0
4.7 out of 5 (328 reviews)
Hide review
Beautiful oasis tucked away on Duval Street The front desk staff (Kim) was very accommodating. She suggested "highlight" activities for us to make the most of our stay. She even took care of making reservations for us to sail on the sunset cruise. The area around the motel and especially the pool is landscaped so beautifully. The motel is ...
  22 May 2017

£229

£229
Map

Recently booked Florida Keys hotels

Artist House on Fleming
3.5 out of 5.0
Last booking: 4 minutes ago
Fairfield Inn and Suites Key West
2.5 out of 5.0
Last booking: 9 minutes ago
Duval House
3.0 out of 5.0
Last booking: 9 minutes ago
Lime Tree Bay Resort
3.5 out of 5.0
Last booking: 9 minutes ago
Amy Slate's Amoray Dive Resort
2.0 out of 5.0
Last booking: 14 minutes ago
Hyatt Place Marathon Florida Keys
3.0 out of 5.0
Last booking: 22 minutes ago
Sombrero Resort & Marina
2.0 out of 5.0
Last booking: 24 minutes ago
The Marker Waterfront Resort Key West
4.0 out of 5.0
Last booking: 30 minutes ago
Fiesta Key RV Resort
2.5 out of 5.0
Last booking: 35 minutes ago

Pocket Guide: Design Hotel Hotels in Florida Keys

Find a Boutique Hotel in Florida Keys

Sometimes the sprawling chain resorts of the Florida Keys can feel a little overwhelming. For something smaller and more individual, stay in a Florida Keys boutique hotel. The local architecture of the area, often with the porches and pillars typical of the Queen Anne style, has led to many unique and beautifully designed smaller boutique hotels.

Stay in stylishly appointed rooms in smaller, more personalised accommodation all across the keys. The majority of Florida Keys’ boutique hotels are in Key West, but there are also options on Islamorada and Key Largo.

Artistic Attractions in Florida Keys

People rushing to the beach in Florida Keys often miss the region’s lively arts scene. Visit the three Key West Art and Historical Society sites to survey artwork by local painters and sculptors. Fort East Martello, one of the society’s three buildings, features sculptures of repurposed junk turned into art by Stanley Papio. The society’s base, in Customs House, also hosts galleries of paintings by Florida Keys residents.

One way to see other art galleries in Florida Keys is to join an art walk. Groups in both Islamorada and Key West go for regular strolls around the neighbourhoods, visiting galleries and sharing ideas.

Stay in a Boutique Hotel during a Florida Keys Festival

Florida Keys has a seemingly constant cycle of arts events across the region. Key Largo, for instance, has an annual film festival dedicated to the work of one of Hollywood’s greatest actors, Humphrey Bogart.

Every November, Key West also holds its own film festival, which welcomes world-famous actors and directors. Most of the islands, from the bigger ones to the tiny Pigeon Key, will host at least one music and art festival at some point during the year. For family fun, don’t miss the Key Largo Pirates’ Fest, when buccaneers invade the island for three days.

The Florida Keys brim with cultural events and boast a vibrant arts scene. Choose a beautiful boutique hotel in Florida Keys and get out about experience its artistic side.